메뉴 건너뛰기




Volumn 24, Issue 5, 2009, Pages 671-675

The bone anabolic carotenoid β-cryptoxanthin enhances transforming growth factor-β1-induced SMAD activation in MC3T3 preosteoblasts

Author keywords

cryptoxanthin; Bone formation; Osteoblast; Osteoporosis; SMAD; Transforming growth factor 1

Indexed keywords

BETA CRYPTOXANTHIN; BONE MORPHOGENETIC PROTEIN 2; LUCIFERASE; SMAD PROTEIN; TRANSFORMING GROWTH FACTOR BETA1;

EID: 70350761408     PISSN: 11073756     EISSN: 1791244X     Source Type: Journal    
DOI: 10.3892/ijmm_00000278     Document Type: Article
Times cited : (27)

References (31)
  • 1
    • 33646396235 scopus 로고    scopus 로고
    • Estrogen deficiency and bone loss: An inflammatory tale
    • Weitzmann MN and Pacifici R: Estrogen deficiency and bone loss: an inflammatory tale. J Clin Invest 116: 1186-1194, 2006.
    • (2006) J Clin Invest , vol.116 , pp. 1186-1194
    • Weitzmann, M.N.1    Pacifici, R.2
  • 2
    • 0001223839 scopus 로고    scopus 로고
    • Isoflavone and bone metabolism: Its cellular mechanism and preventive role in bone loss
    • Yamaguchi M: Isoflavone and bone metabolism: Its cellular mechanism and preventive role in bone loss. J Health Sci 48: 209-222, 2002.
    • (2002) J Health Sci , vol.48 , pp. 209-222
    • Yamaguchi, M.1
  • 3
    • 33750815738 scopus 로고    scopus 로고
    • Regulatory mechanism of food factors in bone metabolism and prevention of osteoporosis
    • Yamaguchi M: Regulatory mechanism of food factors in bone metabolism and prevention of osteoporosis. Yakugaku Zasshi 126: 1117-1137, 2006.
    • (2006) Yakugaku Zasshi , vol.126 , pp. 1117-1137
    • Yamaguchi, M.1
  • 4
    • 1542323775 scopus 로고    scopus 로고
    • Effect of carotenoid on calcium content and alkaline phosphatase activity in rat femoral tissues in vitro: The unique anabolic effect of β-cryptoxanthin
    • Yamaguchi M and Uchiyama S: Effect of carotenoid on calcium content and alkaline phosphatase activity in rat femoral tissues in vitro: The unique anabolic effect of β-cryptoxanthin. Biol Pharm Bull 26: 1188-1191, 2003.
    • (2003) Biol Pharm Bull , vol.26 , pp. 1188-1191
    • Yamaguchi, M.1    Uchiyama, S.2
  • 5
    • 1442330871 scopus 로고    scopus 로고
    • β-Cryptoxanthin stimulates bone formation and inhibits bone resorption in tissue culture in vitro
    • Yamaguchi M and Uchiyama S: β-Cryptoxanthin stimulates bone formation and inhibits bone resorption in tissue culture in vitro. Mol Cell Biochem 258: 137-144, 2004.
    • (2004) Mol Cell Biochem , vol.258 , pp. 137-144
    • Yamaguchi, M.1    Uchiyama, S.2
  • 6
    • 23044450344 scopus 로고    scopus 로고
    • β-Cryptoxanthin stimulates cell proliferation and transcriptional activity in osteoblastic MC3T3-E1 cells
    • Uchiyama S and Yamaguchi M: β-Cryptoxanthin stimulates cell proliferation and transcriptional activity in osteoblastic MC3T3-E1 cells. Int J Mol Med 15: 675-681, 2005.
    • (2005) Int J Mol Med , vol.15 , pp. 675-681
    • Uchiyama, S.1    Yamaguchi, M.2
  • 7
    • 24944457944 scopus 로고    scopus 로고
    • β-Cryptoxanthin stimulates cell differentiation and mineralization in osteoblastic MC3T3-E1 cells
    • Uchiyama S and Yamaguchi M: β-Cryptoxanthin stimulates cell differentiation and mineralization in osteoblastic MC3T3-E1 cells. J Cell Biochem 95: 1224-1234, 2005.
    • (2005) J Cell Biochem , vol.95 , pp. 1224-1234
    • Uchiyama, S.1    Yamaguchi, M.2
  • 8
    • 1542345606 scopus 로고    scopus 로고
    • Inhibitory effect of β-cryptoxanthin on osteoclast-like cell formation in mouse marrow cultures
    • Uchiyama S and Yamaguchi M: Inhibitory effect of β-cryptoxanthin on osteoclast-like cell formation in mouse marrow cultures. Biochem Pharmacol 67: 1297-1305, 2004.
    • (2004) Biochem Pharmacol , vol.67 , pp. 1297-1305
    • Uchiyama, S.1    Yamaguchi, M.2
  • 9
    • 33746397992 scopus 로고    scopus 로고
    • β-Cryptoxanthin stimulates apoptotic cell death and suppresses cell function in osteoclastic cells: Change in their related gene expression
    • Uchiyama S and Yamaguchi M: β-Cryptoxanthin stimulates apoptotic cell death and suppresses cell function in osteoclastic cells: Change in their related gene expression. J Cell Biochem 98: 1185-1195, 2006.
    • (2006) J Cell Biochem , vol.98 , pp. 1185-1195
    • Uchiyama, S.1    Yamaguchi, M.2
  • 10
    • 16544384663 scopus 로고    scopus 로고
    • Oral administration of β-cryptoxanthin induces anabolic effects on bone components in the femoral tissues of rats in vivo
    • Uchiyama S, Sumida T and Yamaguchi M: Oral administration of β-cryptoxanthin induces anabolic effects on bone components in the femoral tissues of rats in vivo. Biol Pharm Bull 27: 232-235, 2004.
    • (2004) Biol Pharm Bull , vol.27 , pp. 232-235
    • Uchiyama, S.1    Sumida, T.2    Yamaguchi, M.3
  • 11
    • 24944449444 scopus 로고    scopus 로고
    • Oral administration of β-cryptoxanthin prevents bone loss in streptozotocin-diabetic rats in vivo
    • Uchiyama S and Yamaguchi M: Oral administration of β-cryptoxanthin prevents bone loss in streptozotocin-diabetic rats in vivo. Biol Pharm Bull 28: 1766-1769, 2005.
    • (2005) Biol Pharm Bull , vol.28 , pp. 1766-1769
    • Uchiyama, S.1    Yamaguchi, M.2
  • 12
    • 33644876408 scopus 로고    scopus 로고
    • Oral administration of β-cryptoxanthin prevents bone loss in ovariectomized rats
    • Uchiyama S and Yamaguchi M: Oral administration of β-cryptoxanthin prevents bone loss in ovariectomized rats. Int J Mol Med 17: 15-20, 2006.
    • (2006) Int J Mol Med , vol.17 , pp. 15-20
    • Uchiyama, S.1    Yamaguchi, M.2
  • 13
    • 33845410105 scopus 로고    scopus 로고
    • Effect of β-cryptoxanthin on circulating bone metabolic markers: Intake of juice (Citrus unshiu) supplemented with β-cryptoxanthin has an effect in menopausal women
    • Yamaguchi M, Igarashi A, Uchiyama S, Sugawara K, Sumida T, Morita S, Ogawa H, Nishitani M and Kajimoto Y: Effect of β-cryptoxanthin on circulating bone metabolic markers: Intake of juice (Citrus unshiu) supplemented with β-cryptoxanthin has an effect in menopausal women. J Health Sci 52: 758-768, 2006.
    • (2006) J Health Sci , vol.52 , pp. 758-768
    • Yamaguchi, M.1    Igarashi, A.2    Uchiyama, S.3    Sugawara, K.4    Sumida, T.5    Morita, S.6    Ogawa, H.7    Nishitani, M.8    Kajimoto, Y.9
  • 15
    • 37749020890 scopus 로고    scopus 로고
    • Sugiura M, Nakamura M, Ogawa K, Ikoma Y, Ando F and Yano M: Bone mineral density in post-menopausal female subjects is associated with serum antioxidant carotenoids. Osteoporos Int 19: 211-219-720, 2008.
    • Sugiura M, Nakamura M, Ogawa K, Ikoma Y, Ando F and Yano M: Bone mineral density in post-menopausal female subjects is associated with serum antioxidant carotenoids. Osteoporos Int 19: 211-219-720, 2008.
  • 17
    • 48749115029 scopus 로고    scopus 로고
    • β-Cryptoxanthin and bone metabolism: The preventive role in osteoporosis
    • Yamaguchi M: β-Cryptoxanthin and bone metabolism: The preventive role in osteoporosis. J Health Sci 54: 356-369, 2008.
    • (2008) J Health Sci , vol.54 , pp. 356-369
    • Yamaguchi, M.1
  • 18
    • 0025128655 scopus 로고
    • Receptors for insulin-like growth factor-I and -II in osteoblast-enriched cultures from fetal rat bone
    • Centrella M, McCarthy TL and Canalis E: Receptors for insulin-like growth factor-I and -II in osteoblast-enriched cultures from fetal rat bone. Endocrinology 126: 39-44, 1990.
    • (1990) Endocrinology , vol.126 , pp. 39-44
    • Centrella, M.1    McCarthy, T.L.2    Canalis, E.3
  • 19
    • 0033680723 scopus 로고    scopus 로고
    • Role of activator protein 1 transcriptional activity in the regulation of gene expression by transforming growth factor β1 and bone morphogenic protein 2 in ROS 17/2.8 osteoblast-like cells
    • Palcy S, Bolivar I and Goltzman D: Role of activator protein 1 transcriptional activity in the regulation of gene expression by transforming growth factor β1 and bone morphogenic protein 2 in ROS 17/2.8 osteoblast-like cells. J Bone Miner Res 15: 2352-2361, 2000.
    • (2000) J Bone Miner Res , vol.15 , pp. 2352-2361
    • Palcy, S.1    Bolivar, I.2    Goltzman, D.3
  • 20
    • 34447509873 scopus 로고    scopus 로고
    • Endogenous TNFalpha lowers maximum peak bone mass and inhibits osteoblastic SMAD activation, through NF-kappaB
    • Li Y, Li A, Strait K, Zhang H, Nanes MS and Weitzmann MN: Endogenous TNFalpha lowers maximum peak bone mass and inhibits osteoblastic SMAD activation, through NF-kappaB. J Bone Miner Res 22: 646-655, 2007.
    • (2007) J Bone Miner Res , vol.22 , pp. 646-655
    • Li, Y.1    Li, A.2    Strait, K.3    Zhang, H.4    Nanes, M.S.5    Weitzmann, M.N.6
  • 22
    • 69549122467 scopus 로고    scopus 로고
    • The bone anabolic carotenoids β-hydroxycinnamic acid and β-cryptoxanthin antagonize NF-?B activation in MC3T3 preosteoblasts
    • Yamaguchi M and Weitzmann MN: The bone anabolic carotenoids β-hydroxycinnamic acid and β-cryptoxanthin antagonize NF-?B activation in MC3T3 preosteoblasts. Mol Med Rep 2: 641-644, 2009.
    • (2009) Mol Med Rep , vol.2 , pp. 641-644
    • Yamaguchi, M.1    Weitzmann, M.N.2
  • 24
    • 0032983542 scopus 로고    scopus 로고
    • Isolation and characterization of MC3T3-E1 preosteoblast subclones with distinct in vitro and in vivo differentiation/mineralization potential
    • Wang D, Christensen K, Chawla K, Xiao G, Krebsbach PH and Franceschi RT: Isolation and characterization of MC3T3-E1 preosteoblast subclones with distinct in vitro and in vivo differentiation/mineralization potential. J Bone Miner Res 14: 893-903, 1999.
    • (1999) J Bone Miner Res , vol.14 , pp. 893-903
    • Wang, D.1    Christensen, K.2    Chawla, K.3    Xiao, G.4    Krebsbach, P.H.5    Franceschi, R.T.6
  • 25
    • 1542314236 scopus 로고    scopus 로고
    • Transforming growth factor beta-mediated transcriptional repression of c-myc is dependent on direct binding of SMAD3 to a novel repressive SMAD binding element
    • Fredderick JP, Liberati NT, Waddell DS, Shi Y and Wang XF: Transforming growth factor beta-mediated transcriptional repression of c-myc is dependent on direct binding of SMAD3 to a novel repressive SMAD binding element. Mol Cell Biol 24: 2546-2559, 2004.
    • (2004) Mol Cell Biol , vol.24 , pp. 2546-2559
    • Fredderick, J.P.1    Liberati, N.T.2    Waddell, D.S.3    Shi, Y.4    Wang, X.F.5
  • 26
    • 53049087888 scopus 로고    scopus 로고
    • Bone morphogenetic protein-SMAD pathway as drug targets for osteoporosis and cancer therapy
    • Li B: Bone morphogenetic protein-SMAD pathway as drug targets for osteoporosis and cancer therapy. Endocr Metab Immune Disord Drug Targets 8: 208-219, 2008.
    • (2008) Endocr Metab Immune Disord Drug Targets , vol.8 , pp. 208-219
    • Li, B.1
  • 27
    • 65949109906 scopus 로고    scopus 로고
    • Reactive oxygen species the generation of urokinase plasminogen activator in human hepatoma cells via MAPK pathways after treatment with hepatocytes growth factor
    • Lee KH and Kim JR: Reactive oxygen species the generation of urokinase plasminogen activator in human hepatoma cells via MAPK pathways after treatment with hepatocytes growth factor. Exp Mol Med 41: 180-188, 2009.
    • (2009) Exp Mol Med , vol.41 , pp. 180-188
    • Lee, K.H.1    Kim, J.R.2
  • 29
    • 0001869451 scopus 로고    scopus 로고
    • Bone formation: Osteoblast lineage cells, growth factor, matrix protein, and the mineralization process
    • Favus MJ ed, 4th edition, Lippincott Williams & Wilkins Press, New York, pp
    • Lian JB, Stein GS, Canalis E, Roky PG and Boskey AL: Bone formation: Osteoblast lineage cells, growth factor, matrix protein, and the mineralization process. In: Primer on the Metabolic Bone Disease and Disorders of Mineral Metabolism. Favus MJ (ed). (4th edition). Lippincott Williams & Wilkins Press, New York, pp14-29, 1999.
    • (1999) Primer on the Metabolic Bone Disease and Disorders of Mineral Metabolism , pp. 14-29
    • Lian, J.B.1    Stein, G.S.2    Canalis, E.3    Roky, P.G.4    Boskey, A.L.5
  • 30
    • 0016755849 scopus 로고
    • Studies on matrix vesicles isolated from chick epiphyseal cartilage. Association of pyrophosphatase and ATPase activities with alkaline phosphatase
    • Majeska RJ and Wuthier RE: Studies on matrix vesicles isolated from chick epiphyseal cartilage. Association of pyrophosphatase and ATPase activities with alkaline phosphatase. Biochim Biophys Acta 391: 51-60, 1975.
    • (1975) Biochim Biophys Acta , vol.391 , pp. 51-60
    • Majeska, R.J.1    Wuthier, R.E.2
  • 31
    • 0030796595 scopus 로고    scopus 로고
    • Vitamin A and carotenoid stimulate differentiation of mouse osteoblastic cells
    • Park CK, Ishimi Y, Ohmura M, Yamaguchi M and Ikegami S: Vitamin A and carotenoid stimulate differentiation of mouse osteoblastic cells. J Nutr Sci Vitaminol 43: 281-296, 1997.
    • (1997) J Nutr Sci Vitaminol , vol.43 , pp. 281-296
    • Park, C.K.1    Ishimi, Y.2    Ohmura, M.3    Yamaguchi, M.4    Ikegami, S.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.