Tumor necrosis factor α represses bone morphogenetic protein (BMP) signaling by interfering with the DNA binding of smads through the activation of NF-κB

Journal of Biological Chemistry

Volumn 284, Issue 51, 2009, Pages 35987-35995

  Yamazaki, Masato ^a   Fukushima, Hidefumi ^a   Shin, Masashi ^a   Katagiri, Takenobu ^b   Doi, Takahiro ^c   Takahashi, Tetsu ^a   Jimi, Eijiro ^a  

^a KYUSHU DENTAL COLLEGE   (Japan)

^b SAITAMA MEDICAL UNIVERSITY   (Japan)

^c RIKEN BIORESOURCE CENTER   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ALKALINE PHOSPHATASE ACTIVITY; BONE FORMATION; BONE MORPHOGENETIC PROTEINS; CHROMATIN IMMUNOPRECIPITATION; DNA BINDING; DOMINANT NEGATIVE; DOSE-DEPENDENT MANNER; IN-VITRO; IN-VIVO; MC3T3-E1 CELL; MESENCHYMAL CELLS; MOBILITY SHIFT ASSAYS; MOLECULAR MECHANISM; MOUSE EMBRYONIC FIBROBLASTS; NUCLEAR TRANSLOCATIONS; OSTEOBLAST DIFFERENTIATION; OVER-EXPRESSION; PROMOTER ACTIVITIES; TARGET GENES; TUMOR NECROSIS FACTORS;

BONE; CELL CULTURE; COMPLEXATION; DNA; ELECTROPHORESIS; GENES; GLYCOPROTEINS; MACROPHAGES; NUCLEIC ACIDS; SIGNALING; TUMORS;

PROTEINS;

3 (4 METHYLPHENYLSULFONYL) 2 PROPENENITRILE; ALKALINE PHOSPHATASE; BONE MORPHOGENETIC PROTEIN; BONE MORPHOGENETIC PROTEIN 2; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; SMAD1 PROTEIN; SMAD4 PROTEIN; SMAD5 PROTEIN; SMAD8 PROTEIN; SYNAPTOTAGMIN I; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ARTICLE; CELL FUNCTION; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DNA BINDING; DOSE RESPONSE; ELECTROPHORESIS; EMBRYO; ENZYME ACTIVATION; ENZYME INHIBITION; GEL MOBILITY SHIFT ASSAY; GENE OVEREXPRESSION; GENE REPRESSION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION;

ACTIVE TRANSPORT, CELL NUCLEUS; ANIMALS; BONE MORPHOGENETIC PROTEIN 2; CELL LINE; CELL NUCLEUS; MICE; MICE, KNOCKOUT; NITRILES; SIGNAL TRANSDUCTION; SMAD PROTEINS; SULFONES; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR-ALPHA;

EID: 72149132820     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.070540     Document Type: Article

References (41)

1. Urist, M. R. (1965) Science 150, 893-899
2. Wozney, J. M., Rosen, V., Celeste, A. J., Mitsock, L. M., Whitters, M. J., Kriz, R. W., Hewick, R. M., and Wang, E. A. (1988) Science 242, 1528-1534
3. Miyazono, K., Maeda, S., and Imamura, T. (2005) Cytokine Growth Factor Rev. 16, 251-263
4. Massagué, J., Seoane, J., and Wotton, D. (2005) Genes Dev. 19, 2783-2810
5. Katagiri, T., Yamaguchi, A., Komaki, M., Abe, E., Takahashi, N., Ikeda, T., Rosen, V., Wozney, J. M., Fujisawa-Sehara, A., and Suda, T. (1994) J. Cell Biol. 127, 1755-1766
6. Kusumoto, K., Bessho, K., Fujimura, K., Akioka, J., Okubo, Y., Wang, Y., Iizuka, T., and Ogawa, Y. (2002) J. Int. Med. Res. 30, 251-259
7. Vaidya, R., Sethi, A., Bartol, S., Jacobson, M., Coe, C., and Craig, J. G. (2008) J. Spinal Disord. Tech. 21, 557-562
8. Buma, P., Arts, J. J., Gardeniers, J. W., Verdonschot, N., and Schreurs, B. W. (2008) J. Biomed. Mater. Res. B Appl. Biomater. 84, 231-239
9. Canalis, E. (1987) Endocrinology 121, 1596-1604
10. Nakase, T., Takaoka, K., Masuhara, K., Shimizu, K., Yoshikawa, H., and Ochi, T. (1997) Bone 21, 17-21
11. Gilbert, L., He, X., Farmer, P., Boden, S., Kozlowski, M., Rubin, J., and Nanes, M. S. (2000) Endocrinology 141, 3956-3964
12. Nanes, M. S. (2003) Gene 321, 1-15
13. Chen, G., and Goeddel, D. V. (2002) Science 296, 1634-1635
14. Bradley, J. R. (2008) J. Pathol. 214, 149-160
15. Ghosh, S., and Hayden, M. S. (2008) Nat. Rev. Immunol. 8, 837-848
16. Karin, M. (2008) Cell Res. 18, 334-342
17. ten Dijke, P. (2006) Curr. Med. Res. Opin. 22, S7-11
18. Haÿ, E., Lemonnier, J., Fromigué, O., and Marie, P. J. (2001) J. Biol. Chem. 276, 29028-29036
19. Haÿ, E., Lemonnier, J., Fromigué, O., Guénou, H., and Marie, P. J. (2004) J. Biol. Chem. 279, 1650-1658
20. Doi, T. S., Takahashi, T., Taguchi, O., Azuma, T., and Obata, Y. (1997) J. Exp. Med. 185, 953-961
21. Katagiri, T., Imada, M., Yanai, T., Suda, T., Takahashi, N., and Kamijo, R. (2002) Genes Cells 7, 949-960
22. Dignam, J. D., Lebovitz, R. M., and Roeder, R. G. (1983) Nucleic Acids Res. 11, 1475-1489
23. Mukai, T., Otsuka, F., Otani, H., Yamashita, M., Takasugi, K., Inagaki, K., Yamamura, M., and Makino, H. (2007) Biochem. Biophys. Res. Commun. 356, 1004-1010
24. Yamamoto, N., Akiyama, S., Katagiri, T., Namiki, M., Kurokawa, T., and Suda, T. (1997) Biochem. Biophys. Res. Commun. 238, 574-580
25. Nishimura, R., Hata, K., Harris, S. E., Ikeda, F., and Yoneda, T. (2002) Bone 31, 303-312
26. Sapkota, G., Alarcón, C., Spagnoli, F. M., Brivanlou, A. H., and Massagué, J. (2007) Mol. Cell 25, 441-454
27. Ishida, W., Hamamoto, T., Kusanagi, K., Yagi, K., Kawabata, M., Takehara, K., Sampath, T. K., Kato, M., and Miyazono, K. (2000) J. Biol. Chem. 275, 6075-6079
28. Ralston, S. H., Russell, R. G., and Gowen, M. (1990) J. Bone Miner. Res. 5, 983-988
29. Pacifici, R., Brown, C., Puscheck, E., Friedrich, E., Slatopolsky, E., Maggio, D., McCracken, R., and Avioli, L. V. (1991) Proc. Natl. Acad. Sci. U.S.A. 88, 5134-5138
30. Ammann, P., Rizzoli, R., Bonjour, J. P., Bourrin, S., Meyer, J. M., Vassalli, P., and Garcia, I. (1997) J. Clin. Invest. 99, 1699-1703
31. Choy, E. H., and Panayi, G. S. (2001) N. Engl. J. Med. 344, 907-916
32. Ranganathan, P. (2008) Curr. Opin. Mol. Ther. 10, 562-567
33. Cenci, S., Weitzmann, M. N., Roggia, C., Namba, N., Novack, D., Woodring, J., and Pacifici, R. (2000) J. Clin. Invest. 106, 1229-1237
34. Kaneki, H., Guo, R., Chen, D., Yao, Z., Schwarz, E. M., Zhang, Y. E., Boyce, B. F., and Xing, L. (2006) J. Biol. Chem. 281, 4326-4333
35. Li, Y., Li, A., Strait, K., Zhang, H., Nanes, M. S., and Weitzmann, M. N. (2007) J. Bone Miner. Res. 22, 646-655
36. Gilbert, L. C., Rubin, J., and Nanes, M. S. (2005) Am. J. Physiol. Endocrinol. Metab. 288, E1011-E1018
37. Eliseev, R. A., Schwarz, E. M., Zuscik, M. J., O'Keefe, R. J., Drissi, H., and Rosier, R. N. (2006) Exp. Cell Res. 312, 40-50
38. Komori, T., Yagi, H., Nomura, S., Yamaguchi, A., Sasaki, K., Deguchi, K., Shimizu, Y., Bronson, R. T., Gao, Y. H., Inada, M., Sato, M., Okamoto, R., Kitamura, Y., Yoshiki, S., and Kishimoto, T. (1997) Cell 89, 755-764
39. Nakashima, K., Zhou, X., Kunkel, G., Zhang, Z., Deng, J. M., Behringer, R. R., and de Crombrugghe, B. (2002) Cell 108, 17-29
40. Gilbert, L., He, X., Farmer, P., Rubin, J., Drissi, H., van Wijnen, A. J., Lian, J. B., Stein, G. S., and Nanes, M. S. (2002) J. Biol. Chem. 277, 2695-2701
41. Lu, X., Gilbert, L., He, X., Rubin, J., and Nanes, M. S. (2006) J. Biol. Chem. 281, 6297-6306