Elucidating the sources of β-catenin dynamics in human neural progenitor cells

PLoS ONE

Volumn 7, Issue 8, 2012, Pages

  Mazemondet, Orianne ^a   John, Mathias ^b   Leye, Stefan ^a   Rolfs, Arndt ^a   Uhrmacher, Adelinde M ^a  

^a UNIVERSITY OF ROSTOCK   (Germany)

^b UNIV LILLE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; WNT PROTEIN;

ARTICLE; CELL CYCLE G1 PHASE; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL CYCLE PHASE; CELL POPULATION; HUMAN; HUMAN CELL; MATHEMATICAL ANALYSIS; MATHEMATICAL MODEL; NERVE CELL; NERVE CELL DIFFERENTIATION; NEURAL STEM CELL; PROTEIN LOCALIZATION; RVM CELL; SIGNAL TRANSDUCTION; STOCHASTIC MODEL;

BETA CATENIN; CELL CYCLE; CELL DIFFERENTIATION; CELL NUCLEUS; COMPUTATIONAL BIOLOGY; COMPUTER SIMULATION; HUMANS; KINETICS; MODELS, STATISTICAL; MODELS, THEORETICAL; NEURODEGENERATIVE DISEASES; NEURONS; SIGNAL TRANSDUCTION; STEM CELLS; STOCHASTIC PROCESSES; TIME FACTORS; TISSUE THERAPY; WNT PROTEINS;

EID: 84865191067     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0042792     Document Type: Article

References (60)

1. Lindvall O, Kokaia Z, Martinez-Serrano A, ((2004)) Stem cell therapy for human neurodegenerative disorders-how to make it work. Nature Medicine 10:: S42--S50.
2. Clelland CD, Barker RA, Watts C, ((2008)) Cell therapy in huntington disease. Neurosurgical Focus 24 (3-4):: E8.
3. Donato R, Miljan EA, Hines SJ, Aouabdi S, Pollock K, et al. ((2007)) Differential development of neuronal physiological responsiveness in two human neural stem cell lines. BMC Neuroscience 8:: 36.
4. Wood-Kaczmar A, Gandhi S, Yao Z, Abramov ASY, Miljan EA, et al. ((2008)) Pink1 is necessary for long term survival and mitochondrial function in human dopaminergic neurons. PLoS ONE 3 (6):: e2455.
5. Le MT, Xie H, Zhou B, Chia PH, Rizk P, et al. ((2009)) Microrna-125b promotes neuronal differentiation in human cells by repressing multiple targets. Molecular and Cellular Biology 29 (19):: 5290--5305.
6. Morgan PJ, Ortinau S, Frahm J, Krueger N, Rolfs A, et al. ((2009)) Protection of neurons derived from human neural progenitor cells by veratridine. Neuroreport 20:: 1225--1229.
7. Castelo-Branco G, Wagner J, Rodriguez FJ, Kele J, Sousa K, et al. ((2003)) Differential regulation of midbrain dopaminergic neuron development by wnt-1, wnt-3a, and wnt-5a. PNAS 100 (22):: 12747--12752.
8. Michaelidis TM, Lie DC, ((2008)) Wnt signaling and neural stem cells: caught in the Wnt web. Cell Tissue Research 331:: 193--210.
9. Israsena N, Hu M, Fu W, Kan L, Kessler JA, ((2004)) The presence of FGF2 signaling determines whether beta-catenin exerts effects on proliferation or neuronal differentiation of neural stem cells. Developmental Biology 268:: 220--231.
10. Schmöle AC, Brennführer A, Karapetyan G, Jaster R, Pews-Davtyan A, et al. ((2010)) Novel indolylmaleimide acts as GSK-3β inhibitor in human neural progenitor cells. Bioorganic & Medicinal Chemistry 18:: 6785--6795.
11. Hübner R, Schmöle AC, Liedmann A, Frech MJ, Rolfs A, et al. ((2010)) Differentiation of human neural progenitor cells regulated by Wnt-3a. Biochemical and Biophysical Research Communications 400:: 358--362.
12. Mazemondet O, Hubner R, Frahm J, Koczan D, Bader B, et al. ((2011)) Quantitative and kinetic profile of Wnt/β-catenin signaling components during human neural progenitor cell differentiation. Cellular & Molecular Biology Letters 16:: 515--538.
13. Lustig B, Jerchow B, Sachs M, Weiler S, Pietsch T, et al. ((2002)) Negative feedback loop of wnt signaling through upregulation of conductin/axin2 in colorectal and liver tumors. Molecular and Cellular Biology 22 (4):: 1184--1193.
14. ten Berge D, Kurek D, Blauwkamp T, Koole W, Maas A, et al. ((2011)) Embryonic stem cells require Wnt proteins to prevent differentiation to epiblast stem cells. Nature Cell Biology 13:: 1070--1075.
15. Wexler EM, Paucer A, Kornblum HI, Palmer TD, Geschwind DH, ((2009)) Endogenous Wnt signaling maintains neural progenitor cell potency. Stem Cells 27:: 1130--1141.
16. Chenn A, Walsh CA, ((2002)) Regulation of cerebral cortical size by control of cell cycle exit in neural precursors. Science 297:: 365.
17. Canning CA, Lee L, Irving C, Mason I, Jones CM, ((2007)) Sustauned interactive Wnt and FGF signaling is required to maintain isthmic identity. Developmental Biology 305 (1):: 276--286.
18. Gillespie DT, ((1977)) Exact stochastic simulation of coupled chemical reactions. Journal of Physical Chemistry 81:: 2340--2361.
19. McAdams HH, Arkin A, ((1999)) It's a noisy business! Genetic regulation at the nanomolar scale. Trends in Genetics 15:: 65--69.
20. Kholodenko BN, ((2006)) Cell-signalling dynamics in time and space. Nature Reviews Molecular Cell Biology 7:: 165--176.
21. Wilkinson DJ, ((2009)) Stochastic modelling for quantitative description of heterogeneous biological systems. Nature Reviews Genetics 10:: 122--133.
22. Wolkenhauer O, Ullah M, Kolch W, Cho KH, ((2004)) Modelling and simulation of intracellular dynamics: Choosing an appropriate framework. IEEE T Nanobiosci 3:: 200--207.
23. Lee E, Salic A, Krüger R, Heinrich R, Kirschner MW, ((2003)) The roles of apc and axin derived from experimental and theoretical analysis of the wnt pathway. PLoS Biol 1:: 116--132.
24. Cho KH, Baek S, Sung MH, ((2006)) Wnt pathway mutations selected by optimal beta-catenin signaling for tumorigenesis. FEBS Letters 580:: 3665--3670.
25. Wawra C, Kühl M, Kestler HA, ((2007)) Extended analyses of the wnt/beta-catenin pathway: Robustness and oscillatory behaviour. FEBS Letters 581:: 4043--4048.
26. Mirams GR, Byrne HM, King JR, ((2010)) A multiple timescale analysis of a mathematical modelof the wnt/beta-catenin signalling pathway. Journal Mathematical Biology 60:: 131--160.
27. van Leeuwen IM, Byrne HM, Jensen OE, King JR, ((2007)) Elucidating the interactions between the adhesive and transcriptional functions of β-catenin in normal and cancerous cells. Journal of Theoretical Biology 247:: 77--102.
28. Kofahl B, Wolf J, ((2010)) Mathematical modelling of wnt/β-catenin signalling. Biochemical Society Transactions 38 (5):: 1281--1285.
29. Towbin H, Staehelin T, Gordon J, ((1979)) Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: Procedure and some applications. PNAS 76:: 4350--4354.
30. Naito AT, Shiojima I, Akazawa H, Hidaka K, Morisaki T, et al. ((2006)) Developmental stagespecific biphasic roles of Wnt/β-catenin signaling in cardiomyogenesis and hematopoiesis. PNAS 103:: 19812--19817.
31. Ueno S, Weidinger G, Osugi T, Kohn AD, Golob JL, et al. ((2007)) Biphasic role for Wnt/β-catenin signaling in cardiac specification in zebrafish and embryonic stem cells. PNAS 104:: 9685--9690.
32. Israsena N, Hu M, Fu W, Kan L, Kessler JA, ((2004)) The presence of FGF2 signaling determines whether β-catenin exerts effects on proliferation or neuronal differentiation of neural stem cells. Developmental Biology 268:: 220--231.
33. Krieghoff E, Behrens J, Mayr B, ((2006)) Nucleo-cytoplasmic distribution of beta-catenin is regulated by retention. Journal of Cell Science 119:: 1453--1463.
34. Tymchyshyn O, Kwiatkowska M (2008) Combining intra- and inter-cellular dynamics to investigate intestinal homeostasis. In: Formal Methods in Systems Biology: First International Workshop, FMSB 2008, Cambridge, UK, June 4-5, 2008, Proceedings. Springer, pp. 63-76.
35. Fradkin LG, Dura JM, Noordermeer JN, ((2010)) Ryks: new partners for Wnts in the developing and regenerating nervous system. Trends in Neurosciences 33:: 84--92.
36. Sethi JK, Vidal-Puig A, ((2010)) Wnt signalling and the control of cellular metabolism. Biochemical Journal 427:: 1--17.
37. Städeli R, Hoffmans R, Basler K, ((2006)) Transcription under the control of nuclear Arm/β-catenin. Current Biology 16:: R378--R385.
38. Schmitz Y, Wolkenhauer O, Rateitschak K, ((2011)) Nucleo-cytoplasmic shuttling of apc can maximize β-catenin/TCF concentration. Journal of Theoretical Biology 279 (1):: 132--142.
39. Mazemondet O, John M, Maus C, Uhrmacher AM, Rolfs A (2009) Intergrating diverse reaction types into stochastic models- a signaling pathway case study in the imperative pi-calculus. In: Rossetti MD, Hill RR, Johansson B, Dunkin A, Ingalls RG, editors, Proceedings of the 2009 Winter Simulation Conference. pp. 932-943.
40. Tan CW, Gardiner BS, Hirokawa Y, Layton MJ, Smith DW, et al. ((2012)) Wnt signalling pathway parameters for mammalian cells. PLoS One 7:: e31882.
41. Bundschuh R, ((2003)) The role of dimerization in noise reduction of simple genetic networks. Journal of Theoretical Biology 220:: 261--269.
42. Morishita Y, ((2004)) Noise-reduction through interaction in gene expression and biochemical reaction processes. Journal of Theoretical Biology 228:: 315--325.
43. Orrell D, Ramsey S, Marelli M, Smith J, Petersen T, et al. ((2006)) Feedback control of stochastic noise in the yeast galactose utilization pathway. Physica D: Nonlinear Phenomena 217:: 64--76.
44. Alam S, Sen A, Behie LA, Kallos MS, ((2004)) Cell cycle kinetics of expanding populations of neural stem and progenitor cells in vitro. Biotechnology and bioengineering 88:: 332--347.
45. Lorenowicz MJ, Korswagen HC, ((2009)) Sailing with the wnt: Charting the wnt processing and secretion route. Experimental Cell Research 315:: 2683--2689.
46. Coudreuse D, Korswagen HC, ((2007)) The making of Wnt: new insights into Wnt maturation, sorting and secretion. Development 134:: 3--12.
47. Semënov MV, Tamai H, Brott BK, Kühl M, Sokol S, et al. ((2001)) Head inducer Dickkopf-1 is a ligand for Wnt coreceptor LRP6. Current Biology 11:: 951--961.
48. Lu W, Liu CC, Thottassery JV, Bu G, Liang Y, ((2010)) Mesd is a universal inhibitor of Wnt coreceptors LRP5 and LRP6 and block Wnt/beta-catenin signaling in cancer cells. Biochemistry 49:: 4635--4643.
49. McNeill H, Woodgett JR, ((2010)) When pathways collide: collaboration and connivance among signalling proteins in development. Nature Reviews Molecular Cell Biology 11:: 404--413.
50. Cotter D, Honavar M, Lovestone S, Raymond L, Kerwin R, et al. ((1999)) Disturbance of Notch-1 and Wnt signalling proteins in neuroglial balloon cells and adbnormal large neurons in focal cortical dysplasia in human cortex. Acta Neuropathologica 98:: 465--472.
51. Kim D, Rath O, Kolch W, Cho KH, ((2007)) A hidden oncogenic positive feedback loop caused by crosstalk between wnt and erk pathways. Oncogene 26:: 4571--4579.
52. Schilling M, Maiwalk T, Bohl S, Kollmann M, Kreutz C, et al. ((2005)) Computational processing and error reduction strategies for standardized quantitative data in biological networks. FEBS Journal 272:: 6400--6411.
53. Hoops S, Sahle S, Gauges R, Lee C, Pahle J, et al. ((2006)) Copasi-a complex pathway simulator. Bioinformatics 22 (24):: 3067--3074.
54. Hooke R, Jeeves TA, ((1961)) "direct search" solution of numerical and statistical problems. Journal of the Association for Computing Machinery 8:: 212--229.
55. Olivier BG, Snoep JJ, ((2004)) Web-based kinetic modelling using jws online. Bioinformatics 20:: 2143--2144.
56. Gibson MA, Bruck J, ((2000)) Efficient exact stochastic simulation of chemical systems with many species and many channels. Journal of Physical Chemistry 104:: 1876--1889.
57. Himmelspach J, Uhrmacher A (2007) Plug'n simulate. In: Proc. of the Annual Simulation Symposium. IEEE Computer Society, pp. 137-143. URL http://dx.doi.org/10.1109/ANSS.2007.34.
58. Ciocchetta F, ((2009)) Bio-pepa with events. Transactions on Computational Systems Biology XI:: 45--68.
59. Schlicht R, Winkler G, ((2008)) A delay stochastic process with applications in molecular biology. Journal of mathematical biology 57:: 613--648.
60. Novere NL, Hucka M, Mi H, Moodie S, Schreiber F, et al. ((2009)) The systems biology graphical notation. Nat Biotech 27:: 735--741.