Nucleo-cytoplasmic shuttling of APC can maximize Β-catenin/TCF concentration

Journal of Theoretical Biology

Volumn 279, Issue 1, 2011, Pages 132-142

  Schmitz, Yvonne ^a   Wolkenhauer, Olaf ^a,b   Rateitschak, Katja ^a  

^a UNIVERSITY OF ROSTOCK   (Germany)

^b STELLENBOSCH UNIVERSITY   (South Africa)

Author keywords

Intracellular transport; Mathematical model; Retention; Steady state analysis; Wnt pathway

Indexed keywords

APC PROTEIN; BETA CATENIN; WNT PROTEIN;

BIOLOGICAL ANALYSIS; COMPUTER SIMULATION; CYTOPLASM; ENZYME ACTIVITY; GENE EXPRESSION; NUMERICAL MODEL; PARAMETERIZATION; PROTEIN;

ALGORITHM; ARTICLE; CELL COMPARTMENTALIZATION; CELL FUNCTION; CELL METABOLISM; CELL NUCLEUS MEMBRANE; COMPLEX FORMATION; CONTROLLED STUDY; CYTOPLASM VESICLE; INTRACELLULAR SPACE; INTRACELLULAR TRANSPORT; MATHEMATICAL COMPUTING; MATHEMATICAL MODEL; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN INTERACTION; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; STEADY STATE;

ADENOMATOUS POLYPOSIS COLI PROTEIN; BETA CATENIN; CELL NUCLEUS; FACILITATED DIFFUSION; KINETICS; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; TCF TRANSCRIPTION FACTORS; WNT PROTEINS;

EID: 79953767798     PISSN: 00225193     EISSN: 10958541     Source Type: Journal    
DOI: 10.1016/j.jtbi.2011.03.018     Document Type: Article

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