Mesd is a universal inhibitor of wnt coreceptors lrp5 and lrp6 and blocks wnt/β-catenin signaling in cancer cells

Biochemistry

Volumn 49, Issue 22, 2010, Pages 4635-4643

  Lu, Wenyan ^a   Liu, Chia Chen ^b   Thottassery, Jaideep V ^a   Bu, Guojun ^b   Li, Yonghe ^a  

^a SOUTHERN RESEARCH INSTITUTE   (United States)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CANCER CELLS; CATENIN SIGNALING; CELL SURFACES; CORECEPTORS; HIGH AFFINITY; LOW DENSITY LIPOPROTEINS; PROSTATE CANCERS; SCLEROSTIN;

CELL MEMBRANES; CELL PROLIFERATION; PHOSPHORYLATION; PROTEINS;

SIGNALING;

BETA CATENIN; CHAPERONE; DICKKOPF 1 PROTEIN; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN 5; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN 6; PROTEIN MESD; SCLEROSTIN; UNCLASSIFIED DRUG; WNT PROTEIN; WNT3A PROTEIN;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CANCER CELL; CELL PROLIFERATION; CELL SURFACE; CONTROLLED STUDY; NONHUMAN; PRIORITY JOURNAL; PROSTATE CANCER; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

ANIMALS; ANTINEOPLASTIC AGENTS; BETA CATENIN; BONE MORPHOGENETIC PROTEINS; CELL LINE; CELL LINE, TUMOR; CELL MEMBRANE; CHO CELLS; CRICETINAE; CRICETULUS; GENETIC MARKERS; GROWTH INHIBITORS; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; LDL-RECEPTOR RELATED PROTEINS; MICE; MOLECULAR CHAPERONES; PROTEIN BINDING; SIGNAL TRANSDUCTION; WNT PROTEINS;

EID: 77953100335     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi1001486     Document Type: Article

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