Screening of selective histone deacetylase inhibitors by proteochemometric modeling

BMC Bioinformatics

Volumn 13, Issue 1, 2012, Pages

  Wu, Dingfeng ^a   Huang, Qi ^a   Zhang, Yida ^a   Zhang, Qingchen ^a   Liu, Qi ^a   Gao, Jun ^a,b   Cao, Zhiwei ^a   Zhu, Ruixin ^a,c  

^a TONGJI UNIVERSITY   (China)

^b SHANGHAI MARITIME UNIVERSITY   (China)

^c LIAONING UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

Author keywords

Histone deacetylases inhibitors; Proteochemometric; Selective inhibitors

Indexed keywords

ANTITUMOR DRUGS; BEST MODEL; CROSS-TERMS; DESCRIPTORS; HDAC INHIBITORS; HISTONE DEACETYLASE INHIBITOR; HISTONE DEACETYLASES; ISOFORMS; PCM MODEL; PREDICTIVE ABILITIES; PROTEIN STRUCTURES; PROTEOCHEMOMETRIC; Q-TESTS; SELECTIVE INHIBITORS; SEQUENCE SIMILARITY; SIDE EFFECT; STRUCTURE SIMILARITY;

PROTEINS;

ANTINEOPLASTIC AGENT; HISTONE DEACETYLASE; HISTONE DEACETYLASE INHIBITOR; ISOPROTEIN; LIGAND;

ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; DRUG SCREENING; HUMAN; METABOLISM; METHODOLOGY; NEOPLASM;

ANTINEOPLASTIC AGENTS; DRUG SCREENING ASSAYS, ANTITUMOR; HISTONE DEACETYLASE INHIBITORS; HISTONE DEACETYLASES; HUMANS; LIGANDS; MODELS, MOLECULAR; NEOPLASMS; PROTEIN ISOFORMS;

MLCS; MLOWN;

EID: 84865189658     PISSN: None     EISSN: 14712105     Source Type: Journal    
DOI: 10.1186/1471-2105-13-212     Document Type: Article

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