C-ABL modulates MAP kinases activation downstream of VEGFR-2 signaling by direct phosphorylation of the adaptor proteins GRB2 and NCK1

Angiogenesis

Volumn 15, Issue 2, 2012, Pages 187-197

  Anselmi, Francesca ^a   Orlandini, Maurizio ^a   Rocchigiani, Marina ^a   De Clemente, Caterina ^a   Salameh, Ahmad ^a   Lentucci, Claudia ^a   Oliviero, Salvatore ^a   Galvagni, Federico ^a  

^a UNIVERSITY OF SIENA   (Italy)

Author keywords

ABL; Angiogenesis; NCK; Signal transduction; VEGF

Indexed keywords

ABELSON KINASE; ADAPTOR PROTEIN; GROWTH FACTOR RECEPTOR BOUND PROTEIN 2; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; NCK1 PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN TYROSINE KINASE; STRESS ACTIVATED PROTEIN KINASE; TYROSINE; UNCLASSIFIED DRUG; VASCULOTROPIN A; VASCULOTROPIN RECEPTOR 2; GRB2 PROTEIN, HUMAN; IMATINIB; NCK PROTEIN; ONCOPROTEIN; PIPERAZINE DERIVATIVE; PROTEIN KINASE INHIBITOR; PYRIMIDINE DERIVATIVE; SIGNAL TRANSDUCING ADAPTOR PROTEIN;

ANGIOGENESIS; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; IN VITRO STUDY; NEGATIVE FEEDBACK; PRIORITY JOURNAL; PROTEIN FUNCTION; RNA INTERFERENCE; SIGNAL TRANSDUCTION; CELL CULTURE; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; GENETICS; IMMUNOLOGY; METABOLISM; MUTATION; PHOSPHORYLATION; PHYSIOLOGY;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; CELLS, CULTURED; ENDOTHELIAL CELLS; ENZYME ACTIVATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GRB2 ADAPTOR PROTEIN; HUMANS; MAP KINASE SIGNALING SYSTEM; MUTATION; NEOVASCULARIZATION, PHYSIOLOGIC; ONCOGENE PROTEINS; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; PIPERAZINES; PROTEIN KINASE INHIBITORS; PROTO-ONCOGENE PROTEINS C-ABL; PYRIMIDINES; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-2;

EID: 84865153310     PISSN: 09696970     EISSN: 15737209     Source Type: Journal    
DOI: 10.1007/s10456-012-9252-6     Document Type: Article

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