High-efficiency gene transfer and selection of human hematopoietic progenitor cells with a hybrid EBV/retroviral vector expressing the green fluorescence protein

Cancer Research

Volumn 58, Issue 1, 1998, Pages 14-19

  Grignani, Francesco ^b,c   Kinsella, Todd ^d   Mencarelli, Amedea ^b   Valtieri, Mauro ^c   Riganelli, Daniela ^b   Grignani, Fausto ^b   Lanfrancone, Luisa ^a   Peschle, Cesare ^c,e   Nolan, Garry P ^d   Pelicci, Pier Giuseppe ^a,b  

^a EUROPEAN INSTITUTE OF ONCOLOGY   (Italy)

^b UNIVERSITY OF PERUGIA   (Italy)

^c ISTITUTO SUPERIORE DI SANITÀ   (Italy)

^d STANFORD UNIVERSITY   (United States)

^e THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DNA REPLICATION ORIGIN; EPSTEIN BARR VIRUS; EXPRESSION VECTOR; FLUORESCENCE ACTIVATED CELL SORTER; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; RETROVIRUS;

3T3 CELLS; ANIMALS; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; HEMATOPOIETIC STEM CELLS; HERPESVIRUS 4, HUMAN; HUMANS; LUMINESCENT PROTEINS; MICE; RETROVIRIDAE; TUMOR CELLS, CULTURED;

EID: 0031984816     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (19)

1. Bagnis, C., Chabannon, C, and Mannoni, P. Gene transfer into haemopoietic cells: a challenge for gene therapy. Gene Ther., 3: 362-364, 1996.
2. Malcom, K., and Brenner, M. D. Gene transfer to hematopoietic cells. N. Engl. J. Med., 5: 337-339, 1996.
3. Chalfie, M., Tu, Y., Euskirchen, G., Ward, W. W., and Prasher, D. C. Green fluorescent protein as a marker for gene expression. Science (Washington DC), 263: 802-805, 1994.
4. Kinsella, T. M., and Nolan, G. P. Episomal vectors rapidly and stably produce high-titer recombinant retrovirus. Hum. Gene Ther., 7: 1405-1413, 1996.
5. Gabbianelli, M., Sargiacomo, M., Pelosi, E., Testa, U., Isacchi, G., and Peschle, C. "Pure" human hematopoietic progenitors: permissive action of basic fibroblast growth factor. Science (Washington DC), 249: 1561-1564, 1990.
6. Labbaye, C., Valtieri, M., Barberi, T., Meccia, E., Masella, B., Pelosi, E., Condorelli, L., Teta, U., and Peschle, C. Differential expression and functional role of GATA-2, NF-E2 and GATA-1 in normal adult hematopoiesis. J. Clin. Invest., 95: 2346-2358, 1995.
7. Rizzuto, R., Brini, M., Pizzo, P., Murgia, M., and Pozzan, T. Chimeric green fluorescent protein as a tool for visualizing subcellular organelles in living cells. Curr. Biol., 5: 635-642, 1995.
8. Guerriero, R., Testa, U., Gabbianelli, M., Mattia, G., Montesoro, E., Macioce, G., Pace, A., Ziegler, B., Hassa, H. J., and Peschle, C. Unilineage megakaryocytic proliferation and differentiation of purified hematopoietic progenitors in serum-free liquid culture. Blood, 86: 3725-3736, 1995.
9. Gabbianelli, M., Pelosi, E., Montesoro, E., Valtieri, M., Luchetti, L., Samoggia, P., Vitelli, L., Barberi, T., Testa, U., Lyman, S., and Peschle, C. Multi-level effects of FLT3 ligand on human hematopoiesis: expansion of putative stem cells and proliferation of granulomonocytic progenitors/monocytic precursors. Blood, 86: 1661-1670, 1995.
10. Valtieri, M., Schirò, R., Chelucci, C., Masella, B., Testa, U., Casella, I., Montesoro, E., Mariani, G., Hassan, J. H., and Peschle, C. Efficient transfer of selectable and membrane reporter genes in hematopoietic progenitor and stem cells purified from peripheral blood. Cancer Res., 54: 4398-4404, 1994.
11. Sambrook, J., Fritsch, E. F., and Maniatis, T. Molecular Cloning: A Laboratory Manual. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press, 1989.
12. Heim, R., Cubitt, A. B., and Tsien, R. Y. Improved green fluorescence. Nature (Lond.), 373: 663-664, 1995.
13. Pelicci, G., Lanfrancone, L., Grignani, F., McGlade, J., Cavallo, F., Forni, G., Nicoletti, I., Grignani, F., Pawson, T., and Pelicci, P. G. A novel transforming protein (SHC) with a SH2 domain is implicated in mitogenic signal transduction. Cell, 70: 93-104, 1992.
14. Flenghi, L., Fagioli, M., Tomassoni, L., Pileri, S., Gambacorta, M., Pacini, R., Grignani, F., Casini, T., Ferrucci, P. F., Martelli, M. F., Pelicci, P. G., and Falini, B. Characterization of a new monoclonal antibody (PG-M3) directed against the amino-terminal portion of the PML gene product: immunocytochemical evidence for high expression of PML proteins on activated macrophages, endothelial cells, and epithelia. Blood, 85: 1871-1880, 1995.
15. Bonini, C., Ferrari, G., Verzeletti, S., Servida, P., Zappone, E., Ruggieri, L., Ponzoni, M., Rossini, S., Mavilio, F., Traversari, C., and Bordignon, C. HSV-TK gene transfer into donor lymphocytes for control of allogenic graft-versus-leukemia. Science (Washington DC), 276: 1719-1724, 1997.
16. Pandolfi, P. P., Grignani, F., Alcalay, M., Mencarelli, A., Biondi, A., LoCoco, F., Grignani, F., and Pelicci, P. G. Structure and origin of the acute promyelocytic leukemia myl/RAR α cDNA and characterization of its retinoid-binding and transactivation properties. Oncogene, 6: 1285-1292, 1991.
17. Migliaccio, E., Mele, S., Salcini, A. E., Pelicci, G., Lai, K. M., Superti-Furga, G., Pawson, T., Di Fiore, P. P., Lanfrancone, L., and Pelicci, P. G. Opposite effects of the p52shc/p46shc and p66shc splicing isoforms on the EGF receptor-MAP kinase-fos signalling pathway. EMBO J., 16: 706-716, 1997.
18. Machl, A. W., Planitzer, S., and Kubbies, M. A novel, membrane receptor-based retroviral vector for Fanconi anemia group C gene therapy. Gene Ther., 4: 339-345, 1997.
19. Migita, M., Medin, J. A., Pawliuk, R., Jacobson, S., Nagle, J. W., Anderson, S., Amiri, M., Humphries, R. K., and Karlsson, S. Selection of transduced CD34+ progenitors and enzymatic correction of cells from Gaucher patients, with bicistronic vectors. Proc. Natl. Acad. Sci. USA, 92: 12075-12079, 1995.