-
1
-
-
84872212304
-
-
HHT Foundation International website (2011)
-
HHT Foundation International website (2011)
-
-
-
-
2
-
-
77955880114
-
Hereditary haemorrhagic telangiectasia: Pathophysiology, diagnosis and treatment
-
20870325 10.1016/j.blre.2010.07.001 1:CAS:528:DC%2BC3cXhsVWmtL%2FO
-
Shovlin CL (2010) Hereditary haemorrhagic telangiectasia: pathophysiology, diagnosis and treatment. Blood Rev 24(6):203-219
-
(2010)
Blood Rev
, vol.24
, Issue.6
, pp. 203-219
-
-
Shovlin, C.L.1
-
3
-
-
67649199928
-
Hereditary haemorrhagic telangiectasia: A clinical and scientific review
-
PMCID: 2986493
-
Govani FS, Shovlin CL (2009) Hereditary haemorrhagic telangiectasia: a clinical and scientific review. Eur J Hum Genet 17(7):860-871. PMCID: 2986493
-
(2009)
Eur J Hum Genet
, vol.17
, Issue.7
, pp. 860-871
-
-
Govani, F.S.1
Shovlin, C.L.2
-
4
-
-
0030050973
-
Mutations in the activin receptor-like kinase 1 gene in hereditary haemorrhagic telangiectasia type 2
-
DOI 10.1038/ng0696-189
-
Johnson DW, Berg JN, Baldwin MA, Gallione CJ, Marondel I, Yoon SJ et al (1996) Mutations in the activin receptor-like kinase 1 gene in hereditary haemorrhagic telangiectasia type 2. Nat Genet 13(2):189-195 (Pubitemid 26000439)
-
(1996)
Nature Genetics
, vol.13
, Issue.2
, pp. 189-195
-
-
Johnson, D.W.1
Berg, J.N.2
Baldwin, M.A.3
Gallione, C.J.4
Marondel, I.5
Yoon -, S.J.6
Stenzel, T.T.7
Speer, M.8
Pericak-Vance, M.A.9
Diamond, A.10
Guttmacher, A.E.11
Jackson, C.E.12
Attisano, L.13
Kucherlapati, R.14
Porteous, M.E.M.15
Marchuk, D.A.16
-
5
-
-
0028171579
-
Endoglin, a TGF-beta binding protein of endothelial cells, is the gene for hereditary haemorrhagic telangiectasia type 1
-
7894484 10.1038/ng1294-345 1:CAS:528:DyaK2MXitl2hsLo%3D
-
McAllister KA, Grogg KM, Johnson DW, Gallione CJ, Baldwin MA, Jackson CE et al (1994) Endoglin, a TGF-beta binding protein of endothelial cells, is the gene for hereditary haemorrhagic telangiectasia type 1. Nat Genet 8(4):345-351
-
(1994)
Nat Genet
, vol.8
, Issue.4
, pp. 345-351
-
-
McAllister, K.A.1
Grogg, K.M.2
Johnson, D.W.3
Gallione, C.J.4
Baldwin, M.A.5
Jackson, C.E.6
-
6
-
-
0033534572
-
Endoglin is an accessory protein that interacts with the signaling receptor complex of multiple members of the transforming growth factor-β superfamily
-
DOI 10.1074/jbc.274.2.584
-
Barbara NP, Wrana JL, Letarte M (1999) Endoglin is an accessory protein that interacts with the signaling receptor complex of multiple members of the transforming growth factor-beta superfamily. J Biol Chem 274(2):584-594 (Pubitemid 29058021)
-
(1999)
Journal of Biological Chemistry
, vol.274
, Issue.2
, pp. 584-594
-
-
Barbara, N.P.1
Wrana, J.L.2
Letarte, M.3
-
7
-
-
21644452716
-
Interaction and functional interplay between endoglin and ALK-1, two components of the endothelial transforming growth factor-β receptor complex
-
DOI 10.1002/jcp.20311
-
Blanco FJ, Santibanez JF, Guerrero-Esteo M, Langa C, Vary CP, Bernabeu C (2005) Interaction and functional interplay between endoglin and ALK-1, two components of the endothelial transforming growth factor-beta receptor complex. J Cell Physiol 204(2):574-584 (Pubitemid 40934653)
-
(2005)
Journal of Cellular Physiology
, vol.204
, Issue.2
, pp. 574-584
-
-
Blanco, F.J.1
Santibanez, J.F.2
Guerrero-Esteo, M.3
Langa, C.4
Vary, C.P.H.5
Bernabeu, C.6
-
8
-
-
70449392400
-
Real-time imaging of de novo arteriovenous malformation in a mouse model of hereditary hemorrhagic telangiectasia
-
PMCID: 2769195
-
Park SO, Wankhede M, Lee YJ, Choi EJ, Fliess N, Choe SW et al (2009) Real-time imaging of de novo arteriovenous malformation in a mouse model of hereditary hemorrhagic telangiectasia. J Clin Invest 119(11):3487-3496. PMCID: 2769195
-
(2009)
J Clin Invest
, vol.119
, Issue.11
, pp. 3487-3496
-
-
Park, S.O.1
Wankhede, M.2
Lee, Y.J.3
Choi, E.J.4
Fliess, N.5
Choe, S.W.6
-
9
-
-
0031039041
-
Mapping of a major genetic modifier of embryonic lethality in TGFβ1 knockout mice
-
DOI 10.1038/ng0297-207
-
Bonyadi M, Rusholme SA, Cousins FM, Su HC, Biron CA, Farrall M et al (1997) Mapping of a major genetic modifier of embryonic lethality in TGF beta 1 knockout mice. Nat Genet 15(2):207-211 (Pubitemid 27061646)
-
(1997)
Nature Genetics
, vol.15
, Issue.2
, pp. 207-211
-
-
Bonyadi, M.1
Rusholme, S.A.B.2
Cousins, F.M.3
Su, H.C.4
Biron, C.A.5
Farrall, M.6
Akhurst, R.J.7
-
10
-
-
0034970744
-
Potential role of modifier genes influencing transforming growth factor-beta1 levels in the development of vascular defects in endoglin heterozygous mice with hereditary hemorrhagic telangiectasia
-
PMCID: 1891990
-
Bourdeau A, Faughnan ME, McDonald ML, Paterson AD, Wanless IR, Letarte M (2001) Potential role of modifier genes influencing transforming growth factor-beta1 levels in the development of vascular defects in endoglin heterozygous mice with hereditary hemorrhagic telangiectasia. Am J Pathol 158(6):2011-2020. PMCID: 1891990
-
(2001)
Am J Pathol
, vol.158
, Issue.6
, pp. 2011-2020
-
-
Bourdeau, A.1
Faughnan, M.E.2
McDonald, M.L.3
Paterson, A.D.4
Wanless, I.R.5
Letarte, M.6
-
11
-
-
0141752813
-
Arterial endothelium-specific activin receptor-like kinase 1 expression suggests its role in arterialization and vascular remodeling
-
DOI 10.1161/01.RES.0000095246.40391.3B
-
Seki T, Yun J, Oh SP (2003) Arterial endothelium-specific activin receptor-like kinase 1 expression suggests its role in arterialization and vascular remodeling. Circ Res 93(7):682-689 (Pubitemid 37222165)
-
(2003)
Circulation Research
, vol.93
, Issue.7
, pp. 682-689
-
-
Seki, T.1
Yun, J.2
Oh, S.P.3
-
12
-
-
67449146883
-
Emerging role of bone morphogenetic proteins in angiogenesis
-
19502096 10.1016/j.cytogfr.2009.05.001 1:CAS:528:DC%2BD1MXnsFaitLw%3D
-
David L, Feige JJ, Bailly S (2009) Emerging role of bone morphogenetic proteins in angiogenesis. Cytokine Growth Factor Rev 20(3):203-212
-
(2009)
Cytokine Growth Factor Rev
, vol.20
, Issue.3
, pp. 203-212
-
-
David, L.1
Feige, J.J.2
Bailly, S.3
-
13
-
-
42549158413
-
Bone morphogenetic protein-9 is a circulating vascular quiescence factor
-
DOI 10.1161/CIRCRESAHA.107.165530
-
David L, Mallet C, Keramidas M, Lamande N, Gasc JM, Dupuis-Girod S et al (2008) Bone morphogenetic protein-9 is a circulating vascular quiescence factor. Circ Res 102(8):914-922 (Pubitemid 351591550)
-
(2008)
Circulation Research
, vol.102
, Issue.8
, pp. 914-922
-
-
David, L.1
Mallet, C.2
Keramidas, M.3
Lamande, N.4
Gasc, J.-M.5
Dupuis-Girod, S.6
Plauchu, H.7
Feige, J.-J.8
Bailly, S.9
-
14
-
-
33847369980
-
Identification of BMP9 and BMP10 as functional activators of the orphan activin receptor-like kinase 1 (ALK1) in endothelial cells
-
DOI 10.1182/blood-2006-07-034124
-
David L, Mallet C, Mazerbourg S, Feige JJ, Bailly S (2007) Identification of BMP9 and BMP10 as functional activators of the orphan activin receptor-like kinase 1 (ALK1) in endothelial cells. Blood 109(5):1953-1961 (Pubitemid 46348192)
-
(2007)
Blood
, vol.109
, Issue.5
, pp. 1953-1961
-
-
David, L.1
Mallet, C.2
Mazerbourg, S.3
Feige, J.-J.4
Bailly, S.5
-
15
-
-
41449101847
-
Crosstalk between vascular endothelial growth factor, notch, and transforming growth factor-β in vascular morphogenesis
-
DOI 10.1161/CIRCRESAHA.107.167171, PII 0000301220080328000005
-
Holderfield MT, Hughes CC (2008) Crosstalk between vascular endothelial growth factor, notch, and transforming growth factor-beta in vascular morphogenesis. Circ Res 102(6):637-652 (Pubitemid 351457853)
-
(2008)
Circulation Research
, vol.102
, Issue.6
, pp. 637-652
-
-
Holderfield, M.T.1
Hughes, C.C.W.2
-
16
-
-
21644461778
-
Crystal structure of BMP-9 and functional interactions with pro-region and receptors
-
DOI 10.1074/jbc.M503328200
-
Brown MA, Zhao Q, Baker KA, Naik C, Chen C, Pukac L et al (2005) Crystal structure of BMP-9 and functional interactions with pro-region and receptors. J Biol Chem 280(26):25111-25118 (Pubitemid 40934603)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.26
, pp. 25111-25118
-
-
Brown, M.A.1
Zhao, Q.2
Baker, K.A.3
Naik, C.4
Chen, C.5
Pukac, L.6
Singh, M.7
Tsareva, T.8
Parice, Y.9
Mahoney, A.10
Roschke, V.11
Sanya, I.12
Choe, S.13
-
17
-
-
77956187467
-
Signaling by members of the TGF-beta family in vascular morphogenesis and disease
-
20656490 10.1016/j.tcb.2010.06.006 1:CAS:528:DC%2BC3cXhtFWqsLbI
-
Pardali E, Goumans MJ, ten Dijke P (2010) Signaling by members of the TGF-beta family in vascular morphogenesis and disease. Trends Cell Biol 20(9):556-567
-
(2010)
Trends Cell Biol
, vol.20
, Issue.9
, pp. 556-567
-
-
Pardali, E.1
Goumans, M.J.2
Ten Dijke, P.3
-
18
-
-
38349173601
-
ALK5- and TGFBR2-independent role of ALK1 in the pathogenesis of hereditary hemorrhagic telangiectasia type 2
-
PMCID: 2200847
-
Park SO, Lee YJ, Seki T, Hong KH, Fliess N, Jiang Z et al (2008) ALK5- and TGFBR2-independent role of ALK1 in the pathogenesis of hereditary hemorrhagic telangiectasia type 2. Blood 111(2):633-642. PMCID: 2200847
-
(2008)
Blood
, vol.111
, Issue.2
, pp. 633-642
-
-
Park, S.O.1
Lee, Y.J.2
Seki, T.3
Hong, K.H.4
Fliess, N.5
Jiang, Z.6
-
19
-
-
30944436695
-
Nonoverlapping expression patterns of ALK1 and ALK5 reveal distinct roles of each receptor in vascular development
-
DOI 10.1038/labinvest.3700376, PII 3700376
-
Seki T, Hong KH, Oh SP (2006) Nonoverlapping expression patterns of ALK1 and ALK5 reveal distinct roles of each receptor in vascular development. Lab Invest A J Tech Methods Pathol 86(2):116-129 (Pubitemid 43117592)
-
(2006)
Laboratory Investigation
, vol.86
, Issue.2
, pp. 116-129
-
-
Seki, T.1
Hong, K.-H.2
Oh, S.P.3
-
20
-
-
0037007226
-
Balancing the activation state of the endothelium via two distinct TGF-β type I receptors
-
DOI 10.1093/emboj/21.7.1743
-
Goumans MJ, Valdimarsdottir G, Itoh S, Rosendahl A, Sideras P, ten Dijke P (2002) Balancing the activation state of the endothelium via two distinct TGF-beta type I receptors. EMBO J 21(7):1743-1753 (Pubitemid 34614630)
-
(2002)
EMBO Journal
, vol.21
, Issue.7
, pp. 1743-1753
-
-
Goumans, M.-J.1
Valdimarsdottir, G.2
Itoh, S.3
Rosendahl, A.4
Sideras, P.5
Ten Dijke, P.6
-
21
-
-
0037114702
-
Activin receptor-like kinase 1 is implicated in the maturation phase of angiogenesis
-
DOI 10.1182/blood.V100.13.4495
-
Lamouille S, Mallet C, Feige JJ, Bailly S (2002) Activin receptor-like kinase 1 is implicated in the maturation phase of angiogenesis. Blood 100(13):4495-4501 (Pubitemid 35429690)
-
(2002)
Blood
, vol.100
, Issue.13
, pp. 4495-4501
-
-
Lamouille, S.1
Mallet, C.2
Felge, J.-J.3
Bailly, S.4
-
22
-
-
33746998477
-
ALK1 signalling analysis identifies angiogenesis related genes and reveals disparity between TGF-β and constitutively active receptor induced gene expression
-
DOI 10.1186/1471-2261-6-13
-
Lux A, Salway F, Dressman HK, Kroner-Lux G, Hafner M, Day PJ et al (2006) ALK1 signalling analysis identifies angiogenesis related genes and reveals disparity between TGF-beta and constitutively active receptor induced gene expression. BMC Cardiovasc Disord 6:13 (Pubitemid 44202717)
-
(2006)
BMC Cardiovascular Disorders
, vol.6
, pp. 13
-
-
Lux, A.1
Salway, F.2
Dressman, H.K.3
Kroner-Lux, G.4
Hafner, M.5
Day, P.J.R.6
Marchuk, D.A.7
Garland, J.8
-
23
-
-
33750565365
-
TGFβ1 induces vasculogenesis and inhibits angiogenic sprouting in an embryonic stem cell differentiation model: Respective contribution of ALK1 and ALK5
-
DOI 10.1634/stemcells.2005-0494
-
Mallet C, Vittet D, Feige JJ, Bailly S (2006) TGFbeta1 induces vasculogenesis and inhibits angiogenic sprouting in an embryonic stem cell differentiation model: respective contribution of ALK1 and ALK5. Stem Cells 24(11):2420-2427 (Pubitemid 44674302)
-
(2006)
Stem Cells
, vol.24
, Issue.11
, pp. 2420-2427
-
-
Mallet, C.1
Vittet, D.2
Feige, J.-J.3
Bailly, S.4
-
24
-
-
0036888627
-
Targets of transcriptional regulation by two distinct type I receptors for transforming growth factor-β in human umbilical vein endothelial cells
-
DOI 10.1002/jcp.10170
-
Ota T, Fujii M, Sugizaki T, Ishii M, Miyazawa K, Aburatani H et al (2002) Targets of transcriptional regulation by two distinct type I receptors for transforming growth factor-beta in human umbilical vein endothelial cells. J Cell Physiol 193(3):299-318 (Pubitemid 35265950)
-
(2002)
Journal of Cellular Physiology
, vol.193
, Issue.3
, pp. 299-318
-
-
Ota, T.1
Fujii, M.2
Sugizaki, T.3
Ishii, M.4
Miyazawa, K.5
Aburatani, H.6
Miyazono, K.7
-
25
-
-
0141428794
-
Controlling the angiogenic switch: A balance between two distinct TGF-β receptor signaling pathways
-
DOI 10.1016/S1050-1738(03)00142-7, PII S1050173803001427
-
Goumans MJ, Lebrin F, Valdimarsdottir G (2003) Controlling the angiogenic switch: a balance between two distinct TGF-b receptor signaling pathways. Trends Cardiovasc Med 13(7):301-307 (Pubitemid 37159396)
-
(2003)
Trends in Cardiovascular Medicine
, vol.13
, Issue.7
, pp. 301-307
-
-
Goumans, M.-J.1
Lebrin, F.2
Valdimarsdottir, G.3
-
26
-
-
12944273545
-
Activin receptor-like kinase 1 modulates transforming growth factor-β1 signaling in the regulation of angiogenesis
-
DOI 10.1073/pnas.97.6.2626
-
Oh SP, Seki T, Goss KA, Imamura T, Yi Y, Donahoe PK et al (2000) Activin receptor-like kinase 1 modulates transforming growth factor-beta 1 signaling in the regulation of angiogenesis. Proc Nat Acad Sci USA 97(6):2626-2631 (Pubitemid 30159221)
-
(2000)
Proceedings of the National Academy of Sciences of the United States of America
, vol.97
, Issue.6
, pp. 2626-2631
-
-
Oh, S.P.1
Seki, T.2
Goss, K.A.3
Imamura, T.4
Yi, Y.5
Donahoe, P.K.6
Li, L.7
Miyazono, K.8
Ten Dijke, P.9
Kim, S.10
Li, E.11
-
27
-
-
0036340364
-
Disruption of acvrl1 increases endothelial cell number in zebrafish cranial vessels
-
Roman BL, Pham VN, Lawson ND, Kulik M, Childs S, Lekven AC et al (2002) Disruption of acvrl1 increases endothelial cell number in zebrafish cranial vessels. Development 129(12):3009-3019 (Pubitemid 34874278)
-
(2002)
Development
, vol.129
, Issue.12
, pp. 3009-3019
-
-
Roman, B.L.1
Pham, V.N.2
Lawson, N.D.3
Kulik, M.4
Childs, S.5
Lekven, A.C.6
Garrity, D.M.7
Moon, R.T.8
Fishman, M.C.9
Lechleider, R.J.10
Wienstein, B.M.11
-
28
-
-
34247331476
-
BMP-9 signals via ALK1 and inhibits bFGF-induced endothelial cell proliferation and VEGF-stimulated angiogenesis
-
DOI 10.1242/jcs.002949
-
Scharpfenecker M, van Dinther M, Liu Z, van Bezooijen RL, Zhao Q, Pukac L et al (2007) BMP-9 signals via ALK1 and inhibits bFGF-induced endothelial cell proliferation and VEGF-stimulated angiogenesis. J Cell Sci 120(Pt 6):964-972 (Pubitemid 46638511)
-
(2007)
Journal of Cell Science
, vol.120
, Issue.6
, pp. 964-972
-
-
Scharpfenecker, M.1
Van Dinther, M.2
Liu, Z.3
Van Bezooijen, R.L.4
Zhao, Q.5
Pukac, L.6
Lowik, C.W.G.M.7
Ten Dijke, P.8
-
29
-
-
0033757655
-
Arteriovenous malformations in mice lacking activin receptor-like kinase-1
-
11062473 10.1038/81634 1:CAS:528:DC%2BD3cXotVWhsb0%3D
-
Urness LD, Sorensen LK, Li DY (2000) Arteriovenous malformations in mice lacking activin receptor-like kinase-1. Nat Genet 26(3):328-331
-
(2000)
Nat Genet
, vol.26
, Issue.3
, pp. 328-331
-
-
Urness, L.D.1
Sorensen, L.K.2
Li, D.Y.3
-
30
-
-
67650188576
-
Bone morphogenetic protein (BMP) and activin type II receptors balance BMP9 signals mediated by activin receptor-like kinase-1 in human pulmonary artery endothelial cells
-
PMCID: 2708876
-
Upton PD, Davies RJ, Trembath RC, Morrell NW (2009) Bone morphogenetic protein (BMP) and activin type II receptors balance BMP9 signals mediated by activin receptor-like kinase-1 in human pulmonary artery endothelial cells. J Biol Chem 284(23):15794-15804. PMCID: 2708876
-
(2009)
J Biol Chem
, vol.284
, Issue.23
, pp. 15794-15804
-
-
Upton, P.D.1
Davies, R.J.2
Trembath, R.C.3
Morrell, N.W.4
-
31
-
-
0035865227
-
Ephrin-B2 selectively marks arterial vessels and neovascularization sites in the adult, with expression in both endothelial and smooth-muscle cells
-
DOI 10.1006/dbio.2000.0112
-
Gale NW, Baluk P, Pan L, Kwan M, Holash J, DeChiara TM et al (2001) Ephrin-B2 selectively marks arterial vessels and neovascularization sites in the adult, with expression in both endothelial and smooth-muscle cells. Dev Biol 230(2):151-160 (Pubitemid 32171414)
-
(2001)
Developmental Biology
, vol.230
, Issue.2
, pp. 151-160
-
-
Gale, N.W.1
Baluk, P.2
Pan, L.3
Kwan, M.4
Holash, J.5
DeChiara, T.M.6
McDonald, D.M.7
Yancopoulos, G.D.8
-
32
-
-
0035865049
-
Expression of ephrinB2 identifies a stable genetic difference between arterial and venous vascular smooth muscle as well as endothelial cells, and marks subsets of microvessels at sites of adult neovascularization
-
DOI 10.1006/dbio.2000.9957
-
Shin D, Garcia-Cardena G, Hayashi S, Gerety S, Asahara T, Stavrakis G et al (2001) Expression of ephrinB2 identifies a stable genetic difference between arterial and venous vascular smooth muscle as well as endothelial cells, and marks subsets of microvessels at sites of adult neovascularization. Dev Biol 230(2):139-150 (Pubitemid 32171413)
-
(2001)
Developmental Biology
, vol.230
, Issue.2
, pp. 139-150
-
-
Shin, D.1
Garcia-Cardena, G.2
Hayashi, S.-I.3
Gerety, S.4
Asahara, T.5
Stavrakis, G.6
Isner, J.7
Folkman, J.8
Gimbrone Jr., M.A.9
Anderson, D.J.10
-
33
-
-
77949357053
-
Notch1 activation in mice causes arteriovenous malformations phenocopied by ephrinB2 and EphB4 mutants
-
PMCID: 2849749
-
Krebs LT, Starling C, Chervonsky AV, Gridley T (2010) Notch1 activation in mice causes arteriovenous malformations phenocopied by ephrinB2 and EphB4 mutants. Genesis 48(3):146-150. PMCID: 2849749
-
(2010)
Genesis
, vol.48
, Issue.3
, pp. 146-150
-
-
Krebs, L.T.1
Starling, C.2
Chervonsky, A.V.3
Gridley, T.4
-
34
-
-
77951200415
-
Ephrin-B2 regulates endothelial cell morphology and motility independently of Eph-receptor binding
-
PMCID: 2848112
-
Bochenek ML, Dickinson S, Astin JW, Adams RH, Nobes CD (2010) Ephrin-B2 regulates endothelial cell morphology and motility independently of Eph-receptor binding. J Cell Sci 123(Pt 8):1235-1246. PMCID: 2848112
-
(2010)
J Cell Sci
, vol.123
, Issue.PART 8
, pp. 1235-1246
-
-
Bochenek, M.L.1
Dickinson, S.2
Astin, J.W.3
Adams, R.H.4
Nobes, C.D.5
-
35
-
-
78649651321
-
EphB4 promotes site-specific metastatic tumor cell dissemination by interacting with endothelial cell-expressed ephrinb2
-
10.1158/1541-7786.MCR-09-0453 1:CAS:528:DC%2BC3cXht12ksLnM
-
Heroult M, Schaffner F, Pfaff D, Prahst C, Kirmse R, Kutschera S et al (2010) EphB4 promotes site-specific metastatic tumor cell dissemination by interacting with endothelial cell-expressed ephrinb2. Mol Cancer Res MCR 8(10):1297-1309
-
(2010)
Mol Cancer Res MCR
, vol.8
, Issue.10
, pp. 1297-1309
-
-
Heroult, M.1
Schaffner, F.2
Pfaff, D.3
Prahst, C.4
Kirmse, R.5
Kutschera, S.6
-
36
-
-
77953022206
-
Ephrin-B2 regulates VEGFR2 function in developmental and tumour angiogenesis
-
20445540 10.1038/nature08995 1:CAS:528:DC%2BC3cXls12qurw%3D
-
Sawamiphak S, Seidel S, Essmann CL, Wilkinson GA, Pitulescu ME, Acker T et al (2010) Ephrin-B2 regulates VEGFR2 function in developmental and tumour angiogenesis. Nature 465(7297):487-491
-
(2010)
Nature
, vol.465
, Issue.7297
, pp. 487-491
-
-
Sawamiphak, S.1
Seidel, S.2
Essmann, C.L.3
Wilkinson, G.A.4
Pitulescu, M.E.5
Acker, T.6
-
37
-
-
77953029002
-
Ephrin-B2 controls VEGF-induced angiogenesis and lymphangiogenesis
-
20445537 10.1038/nature09002 1:CAS:528:DC%2BC3cXls12qur4%3D
-
Wang Y, Nakayama M, Pitulescu ME, Schmidt TS, Bochenek ML, Sakakibara A et al (2010) Ephrin-B2 controls VEGF-induced angiogenesis and lymphangiogenesis. Nature 465(7297):483-486
-
(2010)
Nature
, vol.465
, Issue.7297
, pp. 483-486
-
-
Wang, Y.1
Nakayama, M.2
Pitulescu, M.E.3
Schmidt, T.S.4
Bochenek, M.L.5
Sakakibara, A.6
-
38
-
-
0042121208
-
Angiogenic sprouting and capillary lumen formation modeled by human umbilical vein endothelial cells (HUVEC) in fibrin gels: The role of fibroblasts and Angiopoietin-1
-
DOI 10.1016/S0026-2862(03)00045-1
-
Nakatsu MN, Sainson RC, Aoto JN, Taylor KL, Aitkenhead M, Perez-del-Pulgar S et al (2003) Angiogenic sprouting and capillary lumen formation modeled by human umbilical vein endothelial cells (HUVEC) in fibrin gels: the role of fibroblasts and Angiopoietin-1 small star, filled. Microvasc Res 66(2):102-112 (Pubitemid 36962872)
-
(2003)
Microvascular Research
, vol.66
, Issue.2
, pp. 102-112
-
-
Nakatsu, M.N.1
Sainson, R.C.A.2
Aoto, J.N.3
Taylor, K.L.4
Aitkenhead, M.5
Perez-del-Pulgar, S.6
Carpenter, P.M.7
Hughes, C.C.W.8
-
39
-
-
67449088036
-
The unfolded protein response is necessary but not sufficient to compensate for defects in disulfide isomerization
-
PMCID: 2667727
-
Kim JH, Zhao Y, Pan X, He X, Gilbert HF (2009) The unfolded protein response is necessary but not sufficient to compensate for defects in disulfide isomerization. J Biol Chem 284(16):10400-10408. PMCID: 2667727
-
(2009)
J Biol Chem
, vol.284
, Issue.16
, pp. 10400-10408
-
-
Kim, J.H.1
Zhao, Y.2
Pan, X.3
He, X.4
Gilbert, H.F.5
-
40
-
-
0033554723
-
Id1 and Id3 are required for neurogenesis, angiogenesis and vascularization of tumour xenografts
-
DOI 10.1038/44334
-
Lyden D, Young AZ, Zagzag D, Yan W, Gerald W, O'Reilly R et al (1999) Id1 and Id3 are required for neurogenesis, angiogenesis and vascularization of tumour xenografts [see comments]. Nature 401(6754):670-677 (Pubitemid 29485206)
-
(1999)
Nature
, vol.401
, Issue.6754
, pp. 670-677
-
-
Lyden, D.1
Young, A.Z.2
Zagzag, D.3
Yan, W.4
Gerald, W.5
O'Reilly, R.6
Bader, B.L.7
Hynes, R.O.8
Zhuang, Y.9
Manova, K.10
Benezra, R.11
-
41
-
-
20444495706
-
Cell-autonomous notch signaling regulates endothelial cell branching and proliferation during vascular tubulogenesis
-
DOI 10.1096/fj.04-3172fje
-
Sainson RC, Aoto J, Nakatsu MN, Holderfield M, Conn E, Koller E et al (2005) Cell-autonomous notch signaling regulates endothelial cell branching and proliferation during vascular tubulogenesis. FASEB J 19(8):1027-1029 (Pubitemid 40827740)
-
(2005)
FASEB Journal
, vol.19
, Issue.8
, pp. 1027-1029
-
-
Sainson, R.C.A.1
Aoto, J.2
Nakatsu, M.N.3
Holderfield, M.4
Conn, E.5
Koller, E.6
Hughes, C.C.W.7
-
42
-
-
80054712998
-
The requirement for fibroblasts in angiogenesis: Fibroblast-derived matrix proteins are essential for endothelial cell lumen formation
-
PMCID: 3192859
-
Newman AC, Nakatsu MN, Chou W, Gershon PD, Hughes CC (2011) The requirement for fibroblasts in angiogenesis: fibroblast-derived matrix proteins are essential for endothelial cell lumen formation. Mol Biol Cell 22(20):3791-3800. PMCID: 3192859
-
(2011)
Mol Biol Cell
, vol.22
, Issue.20
, pp. 3791-3800
-
-
Newman, A.C.1
Nakatsu, M.N.2
Chou, W.3
Gershon, P.D.4
Hughes, C.C.5
-
43
-
-
34848842778
-
Activin receptor-like kinase 1 inhibits human microvascular endothelial cell migration: Potential roles for JNK and ERK
-
DOI 10.1002/jcp.21126
-
David L, Mallet C, Vailhe B, Lamouille S, Feige JJ, Bailly S (2007) Activin receptor-like kinase 1 inhibits human microvascular endothelial cell migration: potential roles for JNK and ERK. J Cell Physiol 213(2):484-489 (Pubitemid 47509730)
-
(2007)
Journal of Cellular Physiology
, vol.213
, Issue.2
, pp. 484-489
-
-
David, L.1
Mallet, C.2
Vailhe, B.3
Lamouille, S.4
Feige, J.-J.5
Bailly, S.6
-
44
-
-
0033082959
-
Roles of ephrinB ligands and EphB receptors in cardiovascular development: Demarcation of arterial/venous domains, vascular morphogenesis, and sprouting angiogenesis
-
Adams RH, Wilkinson GA, Weiss C, Diella F, Gale NW, Deutsch U et al (1999) Roles of ephrinB ligands and EphB receptors in cardiovascular development: demarcation of arterial/venous domains, vascular morphogenesis, and sprouting angiogenesis. Genes Dev 13(3):295-306 (Pubitemid 29095801)
-
(1999)
Genes and Development
, vol.13
, Issue.3
, pp. 295-306
-
-
Adams, R.H.1
Wilkinson, G.A.2
Weiss, C.3
Diella, F.4
Gale, N.W.5
Deutsch, U.6
Risau, W.7
Klein, R.8
-
45
-
-
0037815292
-
VEGF guides angiogenic sprouting utilizing endothelial tip cell filopodia
-
DOI 10.1083/jcb.200302047
-
Gerhardt H, Golding M, Fruttiger M, Ruhrberg C, Lundkvist A, Abramsson A et al (2003) VEGF guides angiogenic sprouting utilizing endothelial tip cell filopodia. J Cell Biol 161(6):1163-1177 (Pubitemid 36870177)
-
(2003)
Journal of Cell Biology
, vol.161
, Issue.6
, pp. 1163-1177
-
-
Gerhardt, H.1
Golding, M.2
Fruttiger, M.3
Ruhrberg, C.4
Lundkvist, A.5
Abramsson, A.6
Jeltsch, M.7
Mitchell, C.8
Alitalo, K.9
Shima, D.10
Betsholtz, C.11
-
46
-
-
0035794134
-
The basic helix-loop-helix transcription factor HESR1 regulates endothelial cell tube formation
-
11069914 10.1074/jbc.M008506200 1:CAS:528:DC%2BD3MXhslShsbw%3D
-
Henderson AM, Wang SJ, Taylor AC, Aitkenhead M, Hughes CC (2001) The basic helix-loop-helix transcription factor HESR1 regulates endothelial cell tube formation. J Biol Chem 276(9):6169-6176
-
(2001)
J Biol Chem
, vol.276
, Issue.9
, pp. 6169-6176
-
-
Henderson, A.M.1
Wang, S.J.2
Taylor, A.C.3
Aitkenhead, M.4
Hughes, C.C.5
-
47
-
-
33745186201
-
HESR1/CHF2 suppresses VEGFR2 transcription independent of binding to E-boxes
-
16782059 10.1016/j.bbrc.2006.05.177 1:CAS:528:DC%2BD28XmtlWrs7w%3D
-
Holderfield MT, Henderson Anderson AM, Kokubo H, Chin MT, Johnson RL, Hughes CC (2006) HESR1/CHF2 suppresses VEGFR2 transcription independent of binding to E-boxes. Biochem Biophys Res Commun 346(3):637-648
-
(2006)
Biochem Biophys Res Commun
, vol.346
, Issue.3
, pp. 637-648
-
-
Holderfield, M.T.1
Henderson Anderson, A.M.2
Kokubo, H.3
Chin, M.T.4
Johnson, R.L.5
Hughes, C.C.6
-
48
-
-
0036433637
-
Notch activation during endothelial cell network formation in vitro targets the basic HLH transcription factor HESR-1 and downregulates VEGFR-2/KDR expression
-
DOI 10.1006/mvre.2002.2443
-
Taylor KL, Henderson AM, Hughes CC (2002) Notch Activation during Endothelial Cell Network Formation in Vitro Targets the Basic HLH Transcription Factor HESR-1 and Downregulates VEGFR-2/KDR Expression. Microvasc Res 64(3):372-383 (Pubitemid 35370739)
-
(2002)
Microvascular Research
, vol.64
, Issue.3
, pp. 372-383
-
-
Taylor, K.L.1
Henderson, A.M.2
Hughes, C.C.W.3
-
49
-
-
22244470426
-
Endothelial expression of constitutively active Notch4 elicits reversible arteriovenous malformations in adult mice
-
PMCID: 1175015
-
Carlson TR, Yan Y, Wu X, Lam MT, Tang GL, Beverly LJ et al (2005) Endothelial expression of constitutively active Notch4 elicits reversible arteriovenous malformations in adult mice. Proc Natl Acad Sci 102(28):9884-9889. PMCID: 1175015
-
(2005)
Proc Natl Acad Sci
, vol.102
, Issue.28
, pp. 9884-9889
-
-
Carlson, T.R.1
Yan, Y.2
Wu, X.3
Lam, M.T.4
Tang, G.L.5
Beverly, L.J.6
-
50
-
-
73449088332
-
Biology of vascular malformations of the brain
-
PMCID: 2810509
-
Leblanc GG, Golanov E, Awad IA, Young WL (2009) Biology of vascular malformations of the brain. Stroke 40(12):e694-e702. PMCID: 2810509
-
(2009)
Stroke
, vol.40
, Issue.12
-
-
Leblanc, G.G.1
Golanov, E.2
Awad, I.A.3
Young, W.L.4
-
51
-
-
63649138023
-
Arterial-venous specification during development
-
19286613 10.1161/CIRCRESAHA.108.188805 1:CAS:528:DC%2BD1MXisFeltbc%3D
-
Swift MR, Weinstein BM (2009) Arterial-venous specification during development. Circ Res 104(5):576-588
-
(2009)
Circ Res
, vol.104
, Issue.5
, pp. 576-588
-
-
Swift, M.R.1
Weinstein, B.M.2
-
52
-
-
72649087067
-
Notch-1 signalling is activated in brain arteriovenous malformations in humans
-
PMCID: 2792368
-
ZhuGe Q, Zhong M, Zheng W, Yang GY, Mao X, Xie L et al (2009) Notch-1 signalling is activated in brain arteriovenous malformations in humans. Brain 132(Pt 12):3231-3241. PMCID: 2792368
-
(2009)
Brain
, vol.132
, Issue.PART 12
, pp. 3231-3241
-
-
ZhuGe, Q.1
Zhong, M.2
Zheng, W.3
Yang, G.Y.4
Mao, X.5
Xie, L.6
-
53
-
-
59649092177
-
The control of vascular integrity by endothelial cell junctions: Molecular basis and pathological implications
-
19217423 10.1016/j.devcel.2009.01.004 1:CAS:528:DC%2BD1MXis1aksrw%3D
-
Dejana E, Tournier-Lasserve E, Weinstein BM (2009) The control of vascular integrity by endothelial cell junctions: molecular basis and pathological implications. Dev Cell 16(2):209-221
-
(2009)
Dev Cell
, vol.16
, Issue.2
, pp. 209-221
-
-
Dejana, E.1
Tournier-Lasserve, E.2
Weinstein, B.M.3
-
55
-
-
80455178772
-
ChIP-seq reveals cell type-specific binding patterns of BMP-specific Smads and a novel binding motif
-
PMCID: 3203580
-
Morikawa M, Koinuma D, Tsutsumi S, Vasilaki E, Kanki Y, Heldin CH et al (2011) ChIP-seq reveals cell type-specific binding patterns of BMP-specific Smads and a novel binding motif. Nucleic Acids Res 39(20):8712-8727. PMCID: 3203580
-
(2011)
Nucleic Acids Res
, vol.39
, Issue.20
, pp. 8712-8727
-
-
Morikawa, M.1
Koinuma, D.2
Tsutsumi, S.3
Vasilaki, E.4
Kanki, Y.5
Heldin, C.H.6
-
56
-
-
79955448391
-
Interaction between alk1 and blood flow in the development of arteriovenous malformations
-
PMCID: 3062425
-
Corti P, Young S, Chen CY, Patrick MJ, Rochon ER, Pekkan K et al (2011) Interaction between alk1 and blood flow in the development of arteriovenous malformations. Development 138(8):1573-1582. PMCID: 3062425
-
(2011)
Development
, vol.138
, Issue.8
, pp. 1573-1582
-
-
Corti, P.1
Young, S.2
Chen, C.Y.3
Patrick, M.J.4
Rochon, E.R.5
Pekkan, K.6
-
57
-
-
77952343641
-
BMP-9 induces proliferation of multiple types of endothelial cells in vitro and in vivo
-
20406889 10.1242/jcs.061556 1:CAS:528:DC%2BC3cXotFGrsLY%3D
-
Suzuki Y, Ohga N, Morishita Y, Hida K, Miyazono K, Watabe T (2010) BMP-9 induces proliferation of multiple types of endothelial cells in vitro and in vivo. J Cell Sci 123(Pt 10):1684-1692
-
(2010)
J Cell Sci
, vol.123
, Issue.PART 10
, pp. 1684-1692
-
-
Suzuki, Y.1
Ohga, N.2
Morishita, Y.3
Hida, K.4
Miyazono, K.5
Watabe, T.6
-
58
-
-
76249086873
-
Hereditary hemorrhagic telangiectasia/avastin
-
19998344
-
Davidson TM, Olitsky SE, Wei JL (2010) Hereditary hemorrhagic telangiectasia/avastin. The Laryngoscope 120(2):432-435
-
(2010)
The Laryngoscope
, vol.120
, Issue.2
, pp. 432-435
-
-
Davidson, T.M.1
Olitsky, S.E.2
Wei, J.L.3
|