메뉴 건너뛰기




Volumn 40, Issue 12, 2009, Pages

Biology of vascular malformations of the brain

Author keywords

Angiogenesis; Arteriovenous malformation; Cerebral hemorrhage; Genetics; Physiologic; Vascular malformations

Indexed keywords

ACTIVIN RECEPTOR LIKE KINASE 1; ANGIOGENIC FACTOR; CCM 1 PROTEIN; CCM 2 PROTEIN; CCM 3 PROTEIN; DOXYCYCLINE; ENDOGLIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MINOCYCLINE; REGULATOR PROTEIN; SMAD4 PROTEIN; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 2; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG; VASCULOTROPIN;

EID: 73449088332     PISSN: 00392499     EISSN: None     Source Type: Journal    
DOI: 10.1161/STROKEAHA.109.563692     Document Type: Review
Times cited : (178)

References (94)
  • 1
    • 0038222578 scopus 로고    scopus 로고
    • Prospective, population-based detection of intracranial vascular malformations in adults: The Scottish Intracranial Vascular Malformation Study (SIVMS)
    • DOI 10.1161/01.STR.0000069018.90456.C9
    • Al-Shahi R, Bhattacharya JJ, Currie DG, Papanastassiou V, Ritchie V, Roberts RC, Sellar RJ, Warlow CP. Prospective, population-based detection of intracranial vascular malformations in adults: the Scottish Intracranial Vascular Malformation Study (SIVMS). Stroke. 2003;34: 1163-1169. (Pubitemid 36547507)
    • (2003) Stroke , vol.34 , Issue.5 , pp. 1163-1169
    • Al-Shahi, R.1    Bhattacharya, J.J.2    Currie, D.G.3    Papanastassiou, V.4    Ritchie, V.5    Roberts, R.C.6    Sellar, R.J.7    Warlow, C.P.8
  • 2
    • 0032920232 scopus 로고    scopus 로고
    • Mechanisms of angiogenesis in the brain
    • Plate KH. Mechanisms of angiogenesis in the brain. J Neuropathol Exp Neurol. 1999;58:313-320.
    • (1999) J Neuropathol Exp Neurol , vol.58 , pp. 313-320
    • Plate, K.H.1
  • 3
    • 30744477950 scopus 로고    scopus 로고
    • From angiogenesis to neuropathology
    • Greenberg DA, Jin K. From angiogenesis to neuropathology. Nature. 2005;438:954-959.
    • (2005) Nature , vol.438 , pp. 954-959
    • Greenberg, D.A.1    Jin, K.2
  • 5
    • 0035427865 scopus 로고    scopus 로고
    • Immunogold study of interendothelial junction-associated and glucose transporter proteins during postnatal maturation of the mouse blood-brain barrier
    • Vorbrodt AW, Dobrogowska DH, Tarnawski M. Immunogold study of interendothelial junction-associated and glucose transporter proteins during postnatal maturation of the mouse blood-brain barrier. J Neurocytol. 2001; 30:705-716.
    • (2001) J Neurocytol , vol.30 , pp. 705-716
    • Vorbrodt, A.W.1    Dobrogowska, D.H.2    Tarnawski, M.3
  • 6
    • 0035038659 scopus 로고    scopus 로고
    • The cephalic neural crest provides pericytes and smooth muscle cells to all blood vessels of the face and forebrain
    • Etchevers HC, Vincent C, Le Douarin NM, Couly GF. The cephalic neural crest provides pericytes and smooth muscle cells to all blood vessels of the face and forebrain. Development. 2001;128:1059-1068.
    • (2001) Development , vol.128 , pp. 1059-1068
    • Etchevers, H.C.1    Vincent, C.2    Le Douarin, N.M.3    Couly, G.F.4
  • 7
    • 0027362473 scopus 로고
    • Neovascularization and the appearance of morphological characteristics of the blood-brain barrier in the embryonic mouse central nervous system
    • Bauer HC, Bauer H, Lametschwandtner A, Amberger A, Ruiz P, Steiner M. Neovascularization and the appearance of morphological characteristics of the blood-brain barrier in the embryonic mouse central nervous system. Brain Res Dev Brain Res. 1993;75:269-278.
    • (1993) Brain Res Dev Brain Res , vol.75 , pp. 269-278
    • Bauer, H.C.1    Bauer, H.2    Lametschwandtner, A.3    Amberger, A.4    Ruiz, P.5    Steiner, M.6
  • 8
    • 0032482202 scopus 로고    scopus 로고
    • PDGF, TGF-beta, and het-erotypic cell-cell interactions mediate endothelial cell-induced recruitment of 10t1/2 cells and their differentiation to a smooth muscle fate
    • Hirschi KK, Rohovsky SA, D'Amore PA. PDGF, TGF-beta, and het-erotypic cell-cell interactions mediate endothelial cell-induced recruitment of 10t1/2 cells and their differentiation to a smooth muscle fate. J Cell Biol. 1998;141:805-814.
    • (1998) J Cell Biol , vol.141 , pp. 805-814
    • Hirschi, K.K.1    Rohovsky, S.A.2    D'Amore, P.A.3
  • 9
    • 0032768156 scopus 로고    scopus 로고
    • Role of PDGF-B and PDGFR-beta in recruitment of vascular smooth muscle cells and pericytes during embryonic blood vessel formation in the mouse
    • Hellstrom M, Kalen M, Lindahl P, Abramsson A, Betsholtz C. Role of PDGF-B and PDGFR-beta in recruitment of vascular smooth muscle cells and pericytes during embryonic blood vessel formation in the mouse. Development. 1999;126:3047-3055.
    • (1999) Development , vol.126 , pp. 3047-3055
    • Hellstrom, M.1    Kalen, M.2    Lindahl, P.3    Abramsson, A.4    Betsholtz, C.5
  • 13
    • 0025180876 scopus 로고
    • Learning causes synaptogenesis, whereas motor activity causes angio-genesis, in cerebellar cortex of adult rats
    • Black JE, Isaacs KR, Anderson BJ, Alcantara AA, Greenough WT. Learning causes synaptogenesis, whereas motor activity causes angio-genesis, in cerebellar cortex of adult rats. Proc Natl Acad Sci U S A. 1990;87:5568-5572.
    • (1990) Proc Natl Acad Sci U S A , vol.87 , pp. 5568-5572
    • Black, J.E.1    Isaacs, K.R.2    Anderson, B.J.3    Alcantara, A.A.4    Greenough, W.T.5
  • 14
    • 33845794061 scopus 로고    scopus 로고
    • Whisker stimulation enhances angiogenesis in the barrel cortex following focal ischemia in mice
    • Whitaker VR, Cui L, Miller S, Yu SP, Wei L. Whisker stimulation enhances angiogenesis in the barrel cortex following focal ischemia in mice. J Cereb Blood Flow Metab. 2007;27:57-68.
    • (2007) J Cereb Blood Flow Metab , vol.27 , pp. 57-68
    • Whitaker, V.R.1    Cui, L.2    Miller, S.3    Yu, S.P.4    Wei, L.5
  • 15
    • 33646346397 scopus 로고    scopus 로고
    • Chronic hypoxia and the cerebral circulation
    • Xu K, Lamanna JC. Chronic hypoxia and the cerebral circulation. J Appl Physiol. 2006;100:725-730.
    • (2006) J Appl Physiol , vol.100 , pp. 725-730
    • Xu, K.1    Lamanna, J.C.2
  • 16
    • 0033560932 scopus 로고    scopus 로고
    • Distinct roles for the small GTPases cdc42 and rho in endothelial responses to shear stress
    • Li S, Chen BP, Azuma N, Hu YL, Wu SZ, Sumpio BE, Shyy JY, Chien S. Distinct roles for the small GTPases cdc42 and rho in endothelial responses to shear stress. J Clin Invest. 1999;103:1141-1150.
    • (1999) J Clin Invest , vol.103 , pp. 1141-1150
    • Li, S.1    Chen, B.P.2    Azuma, N.3    Hu, Y.L.4    Wu, S.Z.5    Sumpio, B.E.6    Shyy, J.Y.7    Chien, S.8
  • 17
    • 0037071892 scopus 로고    scopus 로고
    • Coordinated interaction of neurogenesis and angiogenesis in the adult songbird brain
    • Louissaint A Jr, Rao S, Leventhal C, Goldman SA. Coordinated interaction of neurogenesis and angiogenesis in the adult songbird brain. Neuron. 2002;34:945-960.
    • (2002) Neuron , vol.34 , pp. 945-960
    • Louissaint Jr., A.1    Rao, S.2    Leventhal, C.3    Goldman, S.A.4
  • 18
    • 12844268496 scopus 로고    scopus 로고
    • Estradiol regulates angiopoietin-1 mRNA expression through estrogen receptor-alpha in a rodent experimental stroke model
    • Ardelt AA, McCullough LD, Korach KS, Wang MM, Munzenmaier DH, Hurn PD. Estradiol regulates angiopoietin-1 mRNA expression through estrogen receptor-alpha in a rodent experimental stroke model. Stroke. 2005;36:337-341.
    • (2005) Stroke , vol.36 , pp. 337-341
    • Ardelt, A.A.1    McCullough, L.D.2    Korach, K.S.3    Wang, M.M.4    Munzenmaier, D.H.5    Hurn, P.D.6
  • 19
    • 27944446867 scopus 로고    scopus 로고
    • The role of angiopoietins during angiogenesis in gliomas
    • Reiss Y, Machein MR, Plate KH. The role of angiopoietins during angiogenesis in gliomas. Brain Pathol. 2005;15:311-317.
    • (2005) Brain Pathol , vol.15 , pp. 311-317
    • Reiss, Y.1    MacHein, M.R.2    Plate, K.H.3
  • 21
    • 0002245133 scopus 로고
    • Pathology of vascular malformations of the brain
    • Wilson C, Stein B, eds Baltimore: Williams & Wilkins
    • McCormick W. Pathology of vascular malformations of the brain. In: Wilson C, Stein B, eds. Pathology of Vascular Malformations of the Brain. Baltimore: Williams & Wilkins; 1984:44-63.
    • (1984) Pathology of Vascular Malformations of the Brain , pp. 44-63
    • McCormick, W.1
  • 22
    • 9144241086 scopus 로고    scopus 로고
    • Perinidal dilated capillary networks in cerebral arteriovenous malformations
    • discussion 168-170
    • Sato S, Kodama N, Sasaki T, Matsumoto M, Ishikawa T. Perinidal dilated capillary networks in cerebral arteriovenous malformations. Neuro-surgery. 2004;54:163-168; discussion 168-170.
    • (2004) Neuro-surgery , vol.54 , pp. 163-168
    • Sato, S.1    Kodama, N.2    Sasaki, T.3    Matsumoto, M.4    Ishikawa, T.5
  • 23
    • 0025940451 scopus 로고
    • Natural history of the cavernous angioma
    • Robinson JR, Awad IA, Little JR. Natural history of the cavernous angioma. J Neurosurg. 1991;75:709-714.
    • (1991) J Neurosurg , vol.75 , pp. 709-714
    • Robinson, J.R.1    Awad, I.A.2
  • 25
    • 0024494723 scopus 로고
    • Angiographic follow-up study of cerebral arteriovenous malformations with reference to their enlargement and regression
    • Minakawa T, Tanaka R, Koike T, Takeuchi S, Sasaki O. Angiographic follow-up study of cerebral arteriovenous malformations with reference to their enlargement and regression. Neurosurgery. 1989;24:68-74.
    • (1989) Neurosurgery , vol.24 , pp. 68-74
    • Minakawa, T.1    Tanaka, R.2    Koike, T.3    Takeuchi, S.4    Sasaki, O.5
  • 26
    • 0034433472 scopus 로고    scopus 로고
    • Dynamic nature of cavernous malformations: A prospective magnetic resonance imaging study with volumetric analysis
    • Clatterbuck RE, Moriarity JL, Elmaci I, Lee RR, Breiter SN, Rigamonti D. Dynamic nature of cavernous malformations: a prospective magnetic resonance imaging study with volumetric analysis. J Neurosurg. 2000; 93:981-986.
    • (2000) J Neurosurg , vol.93 , pp. 981-986
    • Clatterbuck, R.E.1    Moriarity, J.L.2    Elmaci, I.3    Lee, R.R.4    Breiter, S.N.5    Rigamonti, D.6
  • 28
    • 33847689037 scopus 로고    scopus 로고
    • Growth and regression of arteriovenous malformations in a patient with hereditary hemorrhagic telangiectasia. Case report
    • Du R, Hashimoto T, Tihan T, Young WL, Perry V, Lawton MT. Growth and regression of arteriovenous malformations in a patient with hereditary hemorrhagic telangiectasia. Case report. J Neurosurg. 2007;106: 470-477.
    • (2007) J Neurosurg , vol.106 , pp. 470-477
    • Du, R.1    Hashimoto, T.2    Tihan, T.3    Young, W.L.4    Perry, V.5    Lawton, M.T.6
  • 29
    • 0025971543 scopus 로고
    • Cavernous malformations and capillary telangiectasia: A spectrum within a single pathological entity
    • Rigamonti D, Johnson PC, Spetzler RF, Hadley MN, Drayer BP. Cavernous malformations and capillary telangiectasia: a spectrum within a single pathological entity. Neurosurgery. 1991;28:60-64.
    • (1991) Neurosurgery , vol.28 , pp. 60-64
    • Rigamonti, D.1    Johnson, P.C.2    Spetzler, R.F.3    Hadley, M.N.4    Drayer, B.P.5
  • 30
    • 0025129826 scopus 로고
    • Ultrastructure and three-dimensional organization of the telangiectases of hereditary hemorrhagic telangiectasia
    • Braverman IM, Keh A, Jacobson BS. Ultrastructure and three-dimensional organization of the telangiectases of hereditary hemorrhagic telangiectasia. J Invest Dermatol. 1990;95:422-427.
    • (1990) J Invest Dermatol , vol.95 , pp. 422-427
    • Braverman, I.M.1    Keh, A.2    Jacobson, B.S.3
  • 33
    • 33744900611 scopus 로고    scopus 로고
    • Patterns of expression of the three cerebral cavernous malformation (CCM) genes during embryonic and postnatal brain development
    • Petit N, Blecon A, Denier C, Tournier-Lasserve E. Patterns of expression of the three cerebral cavernous malformation (CCM) genes during embryonic and postnatal brain development. Gene Expr Patterns. 2006; 6:495-503.
    • (2006) Gene Expr Patterns , vol.6 , pp. 495-503
    • Petit, N.1    Blecon, A.2    Denier, C.3    Tournier-Lasserve, E.4
  • 36
    • 48249109455 scopus 로고    scopus 로고
    • Ccm1 cell autonomously regulates endothelial cellular morphogenesis and vascular tubulogenesis in zebrafish
    • Hogan BM, Bussmann J, Wolburg H, Schulte-Merker S. Ccm1 cell autonomously regulates endothelial cellular morphogenesis and vascular tubulogenesis in zebrafish. Hum Mol Genet. 2008;17:2424-2432.
    • (2008) Hum Mol Genet , vol.17 , pp. 2424-2432
    • Hogan, B.M.1    Bussmann, J.2    Wolburg, H.3    Schulte-Merker, S.4
  • 39
    • 59649086507 scopus 로고    scopus 로고
    • Tissue-specific conditional Ccm2 knockout mice establish the essential role of endothelial CCM2 in angiogenesis: Implications for human cerebral cavernous malformations
    • Boulday G, Blecon A, Petit N, Chareyre F, Garcia LA, Niwa-Kawakita M, Giovannini M, Tournier-Lasserve E. Tissue-specific conditional Ccm2 knockout mice establish the essential role of endothelial CCM2 in angiogenesis: implications for human cerebral cavernous malformations. Dis Model Mech. 2009;2:168-177.
    • (2009) Dis Model Mech , vol.2 , pp. 168-177
    • Boulday, G.1    Blecon, A.2    Petit, N.3    Chareyre, F.4    Garcia, L.A.5    Niwa-Kawakita, M.6    Giovannini, M.7    Tournier-Lasserve, E.8
  • 40
    • 66349137330 scopus 로고    scopus 로고
    • Functional analyses of human and zebrafish 18-amino acid in-frame deletion pave the way for domain mapping of the cerebral cavernous malformation 3 protein
    • Voss K, Stahl S, Hogan BM, Reinders J, Schleider E, Schulte-Merker S, Felbor U. Functional analyses of human and zebrafish 18-amino acid in-frame deletion pave the way for domain mapping of the cerebral cavernous malformation 3 protein. Hum Mutat. 2009;30:1003-1011.
    • (2009) Hum Mutat , vol.30 , pp. 1003-1011
    • Voss, K.1    Stahl, S.2    Hogan, B.M.3    Reinders, J.4    Schleider, E.5    Schulte-Merker, S.6    Felbor, U.7
  • 43
    • 41049094560 scopus 로고    scopus 로고
    • Endoglin in angiogenesis and vascular diseases
    • ten Dijke P, Goumans MJ, Pardali E. Endoglin in angiogenesis and vascular diseases. Angiogenesis. 2008;11:79-89.
    • (2008) Angiogenesis , vol.11 , pp. 79-89
    • Ten Dijke, P.1    Goumans, M.J.2    Pardali, E.3
  • 44
    • 0032720393 scopus 로고    scopus 로고
    • A murine model of hereditary hemorrhagic telangiectasia
    • Bourdeau A, Dumont DJ, Letarte M. A murine model of hereditary hemorrhagic telangiectasia. J Clin Invest. 1999;104:1343-1351.
    • (1999) J Clin Invest , vol.104 , pp. 1343-1351
    • Bourdeau, A.1    Dumont, D.J.2    Letarte, M.3
  • 45
    • 0037380583 scopus 로고    scopus 로고
    • Mouse model for hereditary hemorrhagic telangiectasia has a generalized vascular abnormality
    • Torsney E, Charlton R, Diamond AG, Burn J, Soames JV, Arthur HM. Mouse model for hereditary hemorrhagic telangiectasia has a generalized vascular abnormality. Circulation. 2003;107:1653-1657.
    • (2003) Circulation , vol.107 , pp. 1653-1657
    • Torsney, E.1    Charlton, R.2    Diamond, A.G.3    Burn, J.4    Soames, J.V.5    Arthur, H.M.6
  • 49
    • 0141752813 scopus 로고    scopus 로고
    • Arterial endothelium-specific activin receptor-like kinase 1 expression suggests its role in arterialization and vascular remodeling
    • Seki T, Yun J, Oh SP. Arterial endothelium-specific activin receptor-like kinase 1 expression suggests its role in arterialization and vascular remodeling. Circ Res. 2003;93:682-689.
    • (2003) Circ Res , vol.93 , pp. 682-689
    • Seki, T.1    Yun, J.2    Oh, S.P.3
  • 50
    • 0035666199 scopus 로고    scopus 로고
    • Endoglin expression in early development is associated with vasculogenesis and angiogenesis
    • Jonker L, Arthur HM. Endoglin expression in early development is associated with vasculogenesis and angiogenesis. Mech Dev. 2002;110: 193-196.
    • (2002) Mech Dev , vol.110 , pp. 193-196
    • Jonker, L.1    Arthur, H.M.2
  • 52
    • 0033673419 scopus 로고    scopus 로고
    • Endoglin is overexpressed after arterial injury and is required for transforming growth factor-beta-induced inhibition of smooth muscle cell migration
    • Ma X, Labinaz M, Goldstein J, Miller H, Keon WJ, Letarte M, O'Brien E. Endoglin is overexpressed after arterial injury and is required for transforming growth factor-beta-induced inhibition of smooth muscle cell migration. Arterioscler Thromb Vasc Biol. 2000;20:2546-2552.
    • (2000) Arterioscler Thromb Vasc Biol , vol.20 , pp. 2546-2552
    • Ma, X.1    Labinaz, M.2    Goldstein, J.3    Miller, H.4    Keon, W.J.5    Letarte, M.6    O'Brien, E.7
  • 54
    • 0033757655 scopus 로고    scopus 로고
    • Arteriovenous malformations in mice lacking activin receptor-like kinase-1
    • Urness LD, Sorensen LK, Li DY. Arteriovenous malformations in mice lacking activin receptor-like kinase-1. Nat Genet. 2000;26:328-331.
    • (2000) Nat Genet , vol.26 , pp. 328-331
    • Urness, L.D.1    Sorensen, L.K.2    Li, D.Y.3
  • 55
    • 33646828684 scopus 로고    scopus 로고
    • Ultrastructure of perinidal capillaries in cerebral arteriovenous malformations
    • discussion 961-970
    • Tu J, Stoodley MA, Morgan MK, Storer KP. Ultrastructure of perinidal capillaries in cerebral arteriovenous malformations. Neurosurgery. 2006; 58:961-970; discussion 961-970.
    • (2006) Neurosurgery , vol.58 , pp. 961-970
    • Tu, J.1    Stoodley, M.A.2    Morgan, M.K.3    Storer, K.P.4
  • 57
    • 16444373524 scopus 로고    scopus 로고
    • A role for endoglin in coupling eNOS activity and regulating vascular tone revealed in hereditary hemorrhagic telangiectasia
    • Toporsian M, Gros R, Kabir MG, Vera S, Govindaraju K, Eidelman DH, Husain M, Letarte M. A role for endoglin in coupling eNOS activity and regulating vascular tone revealed in hereditary hemorrhagic telangiectasia. Circ Res. 2005;96:684-692.
    • (2005) Circ Res , vol.96 , pp. 684-692
    • Toporsian, M.1    Gros, R.2    Kabir, M.G.3    Vera, S.4    Govindaraju, K.5    Eidelman, D.H.6    Husain, M.7    Letarte, M.8
  • 58
    • 0043164827 scopus 로고    scopus 로고
    • Loss of distinct arterial and venous boundaries in mice lacking endoglin, a vascular-specific TGFbeta coreceptor
    • Sorensen LK, Brooke BS, Li DY, Urness LD. Loss of distinct arterial and venous boundaries in mice lacking endoglin, a vascular-specific TGFbeta coreceptor. Dev Biol. 2003;261:235-250.
    • (2003) Dev Biol , vol.261 , pp. 235-250
    • Sorensen, L.K.1    Brooke, B.S.2    Li, D.Y.3    Urness, L.D.4
  • 62
    • 16844378663 scopus 로고    scopus 로고
    • Biallelic somatic and germ line CCM1 truncating mutations in a cerebral cavernous malformation lesion
    • Gault J, Shenkar R, Recksiek P, Awad IA. Biallelic somatic and germ line CCM1 truncating mutations in a cerebral cavernous malformation lesion. Stroke. 2005;36:872-874.
    • (2005) Stroke , vol.36 , pp. 872-874
    • Gault, J.1    Shenkar, R.2    Recksiek, P.3    Awad, I.A.4
  • 63
    • 60549102885 scopus 로고    scopus 로고
    • Biallelic somatic and germline mutations in cerebral cavernous malformations (Ccm): Evidence for a two-hit mechanism of ccm pathogenesis
    • Akers AL, Johnson E, Steinberg GK, Zabramski JM, Marchuk DA. Biallelic somatic and germline mutations in cerebral cavernous malformations (Ccm): evidence for a two-hit mechanism of ccm pathogenesis. Hum Mol Genet. 2009;18:919-930.
    • (2009) Hum Mol Genet , vol.18 , pp. 919-930
    • Akers, A.L.1    Johnson, E.2    Steinberg, G.K.3    Zabramski, J.M.4    Marchuk, D.A.5
  • 65
    • 60549083320 scopus 로고    scopus 로고
    • A two-hit mechanism causes cerebral cavernous malformations: Complete inactivation of CCM1 CCM2 or CCM3 in affected endothelial cells
    • Pagenstecher A, Stahl S, Sure U, Felbor U. A two-hit mechanism causes cerebral cavernous malformations: complete inactivation of CCM1, CCM2 or CCM3 in affected endothelial cells. Hum Mol Genet. 2009;18: 911-918.
    • (2009) Hum Mol Genet , vol.18 , pp. 911-918
    • Pagenstecher, A.1    Stahl, S.2    Sure, U.3    Felbor, U.4
  • 66
    • 7244251522 scopus 로고    scopus 로고
    • Loss of p53 sensitizes mice with a mutation in Ccm1 (Krit1) to development of cerebral vascular malformations
    • Plummer NW, Gallione CJ, Srinivasan S, Zawistowski JS, Louis DN, Marchuk DA. Loss of p53 sensitizes mice with a mutation in Ccm1 (Krit1) to development of cerebral vascular malformations. Am J Pathol. 2004;165:1509-1518.
    • (2004) Am J Pathol , vol.165 , pp. 1509-1518
    • Plummer, N.W.1    Gallione, C.J.2    Srinivasan, S.3    Zawistowski, J.S.4    Louis, D.N.5    Marchuk, D.A.6
  • 67
    • 33745670360 scopus 로고    scopus 로고
    • Intracranial aneurysms: Links among inflammation, hemodynamics and vascular remodeling
    • Hashimoto T, Meng H, Young WL. Intracranial aneurysms: links among inflammation, hemodynamics and vascular remodeling. Neurol Res. 2006;28:372-380.
    • (2006) Neurol Res , vol.28 , pp. 372-380
    • Hashimoto, T.1    Meng, H.2    Young, W.L.3
  • 68
    • 33748579570 scopus 로고    scopus 로고
    • Expression of hypoxia-inducible factor-1 and vascular endothelial growth factor in response to venous hypertension
    • discussion 687-696
    • Zhu Y, Lawton MT, Du R, Shwe Y, Chen Y, Shen F, Young WL, Yang GY. Expression of hypoxia-inducible factor-1 and vascular endothelial growth factor in response to venous hypertension. Neurosurgery. 2006; 59:687-696; discussion 687-696.
    • (2006) Neurosurgery , vol.59 , pp. 687-696
    • Zhu, Y.1    Lawton, M.T.2    Du, R.3    Shwe, Y.4    Chen, Y.5    Shen, F.6    Young, W.L.7    Yang, G.Y.8
  • 72
    • 18244390729 scopus 로고    scopus 로고
    • Coexpression of angiogenic factors in brain arteriovenous malformations
    • DOI 10.1227/01.NEU.0000157925.19676.C3
    • Hashimoto T, Wu Y, Lawton MT, Yang GY, Barbaro NM, Young WL. Coexpression of angiogenic factors in brain arteriovenous malformations. Neurosurgery. 2005;56:1058-1065; discussion 1058-1065. (Pubitemid 40628114)
    • (2005) Neurosurgery , vol.56 , Issue.5 , pp. 1058-1065
    • Hashimoto, T.1    Wu, Y.2    Lawton, M.T.3    Yang, G.-Y.4    Barbaro, N.M.5    Young, W.L.6
  • 73
    • 3042824996 scopus 로고    scopus 로고
    • Pathobiology of human cerebrovascular malformations: Basic mechanisms and clinical relevance
    • discussion 16-17
    • Gault J, Sarin H, Awadallah NA, Shenkar R, Awad IA. Pathobiology of human cerebrovascular malformations: basic mechanisms and clinical relevance. Neurosurgery. 2004;55:1-16; discussion 16-17.
    • (2004) Neurosurgery , vol.55 , pp. 1-16
    • Gault, J.1    Sarin, H.2    Awadallah, N.A.3    Shenkar, R.4    Awad, I.A.5
  • 75
  • 76
    • 0141737798 scopus 로고    scopus 로고
    • Reinduced expression of developmental proteins (nestin, small heat shock protein) in and around cerebral arteriovenous malformations
    • Ha Y, Kim TS, Yoon DH, Cho YE, Huh SG, Lee KC. Reinduced expression of developmental proteins (nestin, small heat shock protein) in and around cerebral arteriovenous malformations. Clin Neuropathol. 2003;22:252-261.
    • (2003) Clin Neuropathol , vol.22 , pp. 252-261
    • Ha, Y.1    Kim, T.S.2    Yoon, D.H.3    Cho, Y.E.4    Huh, S.G.5    Lee, K.C.6
  • 77
    • 37149043250 scopus 로고    scopus 로고
    • Oligoclonal immune response in cerebral cavernous malformations. Laboratory investigation
    • Shi C, Shenkar R, Batjer HH, Check IJ, Awad IA. Oligoclonal immune response in cerebral cavernous malformations. Laboratory investigation. J Neurosurg. 2007;107:1023-1026.
    • (2007) J Neurosurg , vol.107 , pp. 1023-1026
    • Shi, C.1    Shenkar, R.2    Batjer, H.H.3    Check, I.J.4    Awad, I.A.5
  • 82
    • 0034925464 scopus 로고    scopus 로고
    • Ultrastructural and immunocytochemical evidence that an incompetent blood-brain barrier is related to the pathophysiology of cavernous malformations
    • Clatterbuck RE, Eberhart CG, Crain BJ, Rigamonti D. Ultrastructural and immunocytochemical evidence that an incompetent blood-brain barrier is related to the pathophysiology of cavernous malformations. J Neurol Neurosurg Psychiatry. 2001;71:188-192.
    • (2001) J Neurol Neurosurg Psychiatry , vol.71 , pp. 188-192
    • Clatterbuck, R.E.1    Eberhart, C.G.2    Crain, B.J.3    Rigamonti, D.4
  • 83
    • 32044438698 scopus 로고    scopus 로고
    • Ultrastructural characteristics of hemorrhagic, nonhemorrhagic, and recurrent cavernous malformations
    • Tu J, Stoodley MA, Morgan MK, Storer KP. Ultrastructural characteristics of hemorrhagic, nonhemorrhagic, and recurrent cavernous malformations. J Neurosurg. 2005;103:903-909.
    • (2005) J Neurosurg , vol.103 , pp. 903-909
    • Tu, J.1    Stoodley, M.A.2    Morgan, M.K.3    Storer, K.P.4
  • 84
    • 39549094209 scopus 로고    scopus 로고
    • Feasibility of minocycline and doxycycline use as potential vasculostatic therapy for brain vascular malformations: Pilot study of adverse events and tolerance
    • Frenzel T, Lee CZ, Kim H, Quinnine NJ, Hashimoto T, Lawton MT, Guglielmo BJ, McCulloch CE, Young WL. Feasibility of minocycline and doxycycline use as potential vasculostatic therapy for brain vascular malformations: pilot study of adverse events and tolerance. Cerebrovasc Dis. 2008;25:157-163.
    • (2008) Cerebrovasc Dis , vol.25 , pp. 157-163
    • Frenzel, T.1    Lee, C.Z.2    Kim, H.3    Quinnine, N.J.4    Hashimoto, T.5    Lawton, M.T.6    Guglielmo, B.J.7    McCulloch, C.E.8    Young, W.L.9
  • 85
    • 58149326884 scopus 로고    scopus 로고
    • Hemorrhage from cavernous malformations of the brain: Definition and reporting standards. Angioma Alliance Scientific Advisory Board
    • Al-Shahi Salman R, Berg MJ, Morrison L, Awad IA. Hemorrhage from cavernous malformations of the brain: definition and reporting standards. Angioma Alliance Scientific Advisory Board. Stroke. 2008;39:3222-3230.
    • (2008) Stroke , vol.39 , pp. 3222-3230
    • Al-Shahi Salman, R.1    Berg, M.J.2    Morrison, L.3    Awad, I.A.4
  • 86
    • 60149112895 scopus 로고    scopus 로고
    • Outcome after spontaneous and arteriovenous malformation-related intracerebral haemorrhage: Population-based studies
    • van Beijnum J, Lovelock CE, Cordonnier C, Rothwell PM, Klijn CJ, Al-Shahi Salman R. Outcome after spontaneous and arteriovenous malformation-related intracerebral haemorrhage: population-based studies. Brain. 2009;132:537-543.
    • (2009) Brain , vol.132 , pp. 537-543
    • Van Beijnum, J.1    Lovelock, C.E.2    Cordonnier, C.3    Rothwell, P.M.4    Klijn, C.J.5    Al-Shahi Salman, R.6
  • 88
    • 35548936992 scopus 로고    scopus 로고
    • KRIT-1/CCM1 is a RAP1 effector that regulates endothelial cell cell junctions
    • Glading A, Han J, Stockton RA, Ginsberg MH. KRIT-1/CCM1 is a RAP1 effector that regulates endothelial cell cell junctions. J Cell Biol. 2007; 179:247-254.
    • (2007) J Cell Biol , vol.179 , pp. 247-254
    • Glading, A.1    Han, J.2    Stockton, R.A.3    Ginsberg, M.H.4
  • 90
    • 67649397771 scopus 로고    scopus 로고
    • Cerebral cavernous malformation 2 protein promotes SMAD ubiquitin regulatory factor 1-mediated RhoA degradation in endothelial cells
    • Crose LE, Hilder TL, Sciaky N, Johnson GL. Cerebral cavernous malformation 2 protein promotes SMAD ubiquitin regulatory factor 1-mediated RhoA degradation in endothelial cells. J Biol Chem. 2009; 284:13301-13305.
    • (2009) J Biol Chem , vol.284 , pp. 13301-13305
    • Crose, L.E.1    Hilder, T.L.2    Sciaky, N.3    Johnson, G.L.4
  • 91
    • 34250330782 scopus 로고    scopus 로고
    • Pdcd10 interacts with Ste20-related kinase MST4 to promote cell growth and transformation via modulation of the ERK pathway
    • Ma X, Zhao H, Shan J, Long F, Chen Y, Chen Y, Zhang Y, Han X, Ma D. Pdcd10 interacts with Ste20-related kinase MST4 to promote cell growth and transformation via modulation of the ERK pathway. Mol Biol Cell. 2007;18:1965-1978.
    • (2007) Mol Biol Cell , vol.18 , pp. 1965-1978
    • Ma, X.1    Zhao, H.2    Shan, J.3    Long, F.4    Chen, Y.5    Chen, Y.6    Zhang, Y.7    Han, X.8    Ma, D.9
  • 92
    • 58149230979 scopus 로고    scopus 로고
    • TGF-beta signaling in vascular biology and dysfunction
    • Goumans MJ, Liu Z, ten Dijke P. TGF-beta signaling in vascular biology and dysfunction. Cell Res. 2009;19:116-127.
    • (2009) Cell Res , vol.19 , pp. 116-127
    • Goumans, M.J.1    Liu, Z.2    Ten Dijke, P.3
  • 93
    • 36448936383 scopus 로고    scopus 로고
    • TGFbeta-SMAD signal transduction: Molecular specificity and functional flexibility
    • Schmierer B, Hill CS. TGFbeta-SMAD signal transduction: molecular specificity and functional flexibility. Nat Rev Mol Cell Biol. 2007;8: 970-982.
    • (2007) Nat Rev Mol Cell Biol , vol.8 , pp. 970-982
    • Schmierer, B.1    Hill, C.S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.