Tetrameric structure of the GlfT2 galactofuranosyltransferase reveals a scaffold for the assembly of mycobacterial arabinogalactan

Journal of Biological Chemistry

Volumn 287, Issue 33, 2012, Pages 28132-28143

  Wheatley, Robert W ^a   Zheng, Ruixiang Blake ^a,b   Richards, Michele R ^a,b   Lowary, Todd L ^a,b   Ng, Kenneth K S ^a,b  

^a UNIVERSITY OF CALGARY   (Canada)

^b UNIVERSITY OF ALBERTA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVE SITE; ARABINOGALACTAN; C-TERMINAL DOMAINS; CENTRAL CORE; GALACTANS; GLYCOSIDIC LINKAGES; GLYCOSYLTRANSFERASES; HOMOTETRAMERS; KINETIC STUDY; MEMBRANE BILAYERS; MEMBRANE BINDING; MULTIDOMAIN STRUCTURE; MYCOBACTERIAL; MYCOBACTERIAL CELLS; N-TERMINALS; POSITIVELY CHARGED; PROCESSIVITY; PROTOMERS; SITE DIRECTED MUTAGENESIS; TETRAMERIC STRUCTURES;

BIOCHEMISTRY; ENZYMES; X RAY CRYSTALLOGRAPHY;

CRYSTAL STRUCTURE;

ARABINOGALACTAN; GALACTOFURANOSYLTRANSFERASE 2; GLYCOSYLTRANSFERASE; SCAFFOLD PROTEIN; TETRAMER; UNCLASSIFIED DRUG; URIDINE DIPHOSPHATE;

ALPHA HELIX; AMINO TERMINAL SEQUENCE; ARTICLE; BACTERIAL CELL WALL; BILAYER MEMBRANE; CARBOHYDRATE SYNTHESIS; CARBOXY TERMINAL SEQUENCE; CATALYSIS; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME CONFORMATION; ENZYME LOCALIZATION; ENZYME STRUCTURE; ENZYME SUBSTRATE COMPLEX; HYDROPHOBICITY; MEMBRANE BINDING; MOLECULAR DOCKING; MOLECULAR RECOGNITION; MYCOBACTERIUM; NONHUMAN; NUCLEOTIDE BINDING SITE; PRIORITY JOURNAL; PROTEIN DOMAIN; SITE DIRECTED MUTAGENESIS; STRUCTURE ANALYSIS; SURFACE PROPERTY; X RAY CRYSTALLOGRAPHY;

BACTERIAL PROTEINS; CRYSTALLOGRAPHY, X-RAY; GALACTANS; GALACTOSE; GALACTOSYLTRANSFERASES; KINETICS; MUTAGENESIS, SITE-DIRECTED; MYCOBACTERIUM TUBERCULOSIS; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, TERTIARY; URIDINE DIPHOSPHATE;

EID: 84865045770     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.347484     Document Type: Article

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