STD-NMR studies of two acceptor substrates of GlfT2, a galactofuranosyltransferase from Mycobacterium tuberculosis: Epitope mapping studies

Bioorganic and Medicinal Chemistry

Volumn 18, Issue 14, 2010, Pages 5123-5128

  Szczepina, Monica G ^a   Zheng, Ruixiang B ^b   Completo, Gladys C ^b   Lowary, Todd L ^b   Pinto, B Mario ^a  

^a SIMON FRASER UNIVERSITY   (Canada)

^b UNIVERSITY OF ALBERTA   (Canada)

Author keywords

Epitope mapping; Galactofuranosyltransferase; GlfT2; STD NMR; Trisaccharide substrates

Indexed keywords

GALACTAN; GALACTOFURANOSYLTRANSFERASE; NUCLEOTIDE; POLYMER; PROTEIN GLFT1; PROTEIN GLFT2; TETRASACCHARIDE; TRANSFERASE; TRISACCHARIDE; UNCLASSIFIED DRUG; URIDINE DIPHOSPHATE; URIDINE DIPHOSPHATE GALACTOFURANOSE;

ANALYTIC METHOD; ARTICLE; CARBOHYDRATE SYNTHESIS; ENZYME ACTIVE SITE; ENZYME MECHANISM; EPITOPE MAPPING; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; NUCLEAR OVERHAUSER EFFECT; PHOSPHORUS NUCLEAR MAGNETIC RESONANCE; PROTON NUCLEAR MAGNETIC RESONANCE;

CARBOHYDRATE SEQUENCE; CATALYTIC DOMAIN; GALACTOSE; GALACTOSYLTRANSFERASES; MOLECULAR SEQUENCE DATA; MYCOBACTERIUM TUBERCULOSIS; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PROTEIN BINDING; SUBSTRATE SPECIFICITY; TRISACCHARIDES; URIDINE DIPHOSPHATE;

MYCOBACTERIUM TUBERCULOSIS;

EID: 77955320710     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2010.05.069     Document Type: Article

References (32)

1. For perspective and current statistics: T.M. Daniel Respir. Med. 100 2006 1862
2. For perspective and current statistics: http://www.who.int/tb/en/.
3. S. Mahapatra, J. Basu, P.J. Brennan, and D.C. Crick S.T. Cole, K.D. Eisenach, D.N. McMurray, J.W.R. Jacobs, Tuberculosis and the Tubercle Bacillus 2005 American Society for Microbiology Washington, DC 275
4. T.L. Lowary B.O. Fraser-Reid, K. Tatsuta, J. Thiem, Glycoscience: Chemistry and Chemical Biology Vol. 3 2001 Springer Berlin 2005
5. G.S. Besra, K.H. Khoo, M.R. McNeil, A. Dell, H.R. Morris, and P.J. Brennan Biochemistry 34 1995 4257
6. L.J. Alderwick, E. Radmacher, M. Seidel, R. Gande, P.G. Hitchen, H.R. Morris, A. Dell, H. Sahm, L. Eggeling, and G.S. Besra J. Biol. Chem. 280 2005 32362
7. R.M. de Lederkremer, and W. Colli Glycobiology 5 1995 547
8. S.M. Beverley, K.L. Owens, M. Showalter, C.L. Griffith, T.L. Doering, V.C. Jones, and M.R. McNeil Eukaryot. Cell 4 2005 1147
9. W. Morelle, M. Bernard, J.P. Debeaupuis, M. Buitrago, M. Tabouret, and J.P. Latge Eukaryot. Cell 4 2005 1308
10. J.B. Houseknecht, and T.L. Lowary Curr. Opin. Chem. Biol. 5 2001 677
11. M.R. Richards, and T.L. Lowary ChemBioChem 10 2009 1920
12. S. Berg, D. Kaur, M. Jackson, and P.J. Brennan Glycobiology 17 2007 35R
13. S. Bhamidi, M.S. Scherman, C.D. Rithner, J.E. Prenni, D. Chatterjee, K.H. Khoo, and M.R. McNeil J. Biol. Chem. 283 2008 12992
14. P.H. Tam, and T.L. Lowary Curr. Opin. Chem. Biol. 13 2009 618
15. M. Belanova, P. Dianiskova, P.J. Brennan, G.C. Completo, N.L. Rose, T.L. Lowary, and K. Mikusova J. Bacteriol. 190 2008 1141
16. K. Mikusova, M. Belanova, J. Kordulakova, K. Honda, M.R. McNeil, S. Mahapatra, D.C. Crick, and P.J. Brennan J. Bacteriol. 188 2006 6592
17. K. Mikusova, T. Yagi, R. Stern, M.R. McNeil, G.S. Besra, D.C. Crick, and P.J. Brennan J. Biol. Chem. 275 2000 33890
18. L. Kremer, L.G. Dover, C. Morehouse, P. Hitchin, M. Everett, H.R. Morris, A. Dell, P.J. Brennan, M.R. McNeil, C. Flaherty, K. Duncan, and G.S. Besra J. Biol. Chem. 276 2001 26430
19. L.J. Alderwick, L.G. Dover, N. Veerapen, S.S. Gurcha, L. Kremer, D.L. Roper, A.K. Pathak, R.C. Reynolds, and G.S. Besra Protein Expr. Purif. 58 2008 332
20. N.L. Rose, G.C. Completo, S.J. Lin, M. McNeil, M.M. Palcic, and T.L. Lowary J. Am. Chem. Soc. 128 2006 6721
21. J.F. May, R.A. Splain, C. Brotschi, and L.L. Kiessling Proc. Natl. Acad. Sci. U.S.A. 106 2009 11851
22. M.G. Szczepina, R.B. Zheng, G.C. Completo, T.L. Lowary, and B.M. Pinto ChemBioChem 10 2009 2052
23. G.C. Completo, and T.L. Lowary J. Org. Chem. 73 2008 4513
24. M. Mayer, and B. Meyer Angew. Chem., Int. Ed. 38 1999 1784
25. C.A. Fyfe, and D.H. Brouwer J. Am. Chem. Soc. 128 2006 11860
26. T. Weimar, B. Stoffer, B. Svensson, and B.M. Pinto Biochemistry 39 2000 300
27. M.A. Macnaughtan, M. Kamar, G. Alvarez-Manilla, A. Venot, J. Glushka, J.M. Pierce, and J.H. Prestegard J. Mol. Biol. 366 2007 1266
28. F. Pan, M. Jackson, Y.F. Ma, and M. McNeil J. Bacteriol. 183 2001 3991
29. B.C. de Jong, D.M. Israelski, E.L. Corbett, and P.M. Small Annu. Rev. Med. 55 2004 283
30. N.L. Rose, R.B. Zheng, J. Pearcey, R. Zhou, G.C. Completo, and T.L. Lowary Carbohydr. Res. 343 2008 2130
31. J. Angulo, B. Langpap, A. Blume, T. Biet, B. Meyer, N.R. Krishna, H. Peters, M.M. Palcic, and T. Peters J. Am. Chem. Soc. 128 2006 13529
32. R.E. Lee, P.J. Brennan, and G.S. Besra Glycobiology 7 1997 1121