PI3K/Akt pathway mediates high glucose-induced lipid accumulation in human renal proximal tubular cells via spliced XBP-1

Journal of Cellular Biochemistry

Volumn 113, Issue 10, 2012, Pages 3288-3298

  Zhao, Song ^a   Zhu, Lin ^a   Duan, Huijun ^a   Liu, Shuxia ^a   Liu, Qingjuan ^a   Liu, Wei ^a   Hao, Jun ^a  

^a HEBEI MEDICAL UNIVERSITY   (China)

Author keywords

high glucose; lipogenesis; PI3K AKT; renal proximal tubular cells; XBP 1

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; ACETYL COENZYME A CARBOXYLASE; ADIPOPHILIN; FATTY ACID SYNTHASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; SHORT HAIRPIN RNA; TRIACYLGLYCEROL; X BOX BINDING PROTEIN 1;

ARTICLE; CONTROLLED STUDY; ENZYME INHIBITION; GENE SILENCING; GLUCOSE INTAKE; HUMAN; HUMAN CELL; KIDNEY PROXIMAL TUBULE; KIDNEY TUBULE CELL; LIPID STORAGE; LIPOGENESIS; PRIORITY JOURNAL; PROTEIN PROCESSING; SIGNAL TRANSDUCTION; UPREGULATION;

CELL LINE; CHROMONES; DNA-BINDING PROTEINS; FATTY ACID SYNTHETASE COMPLEX, TYPE I; GENE SILENCING; GENETIC VECTORS; GLUCOSE; HUMANS; IMMUNOHISTOCHEMISTRY; KIDNEY TUBULES, PROXIMAL; LIPID METABOLISM; LIPOGENESIS; MORPHOLINES; PHOSPHATIDYLINOSITOL 3-KINASES; PROTEIN SPLICING; PROTO-ONCOGENE PROTEINS C-AKT; RNA, MESSENGER; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TIME FACTORS; TRANSCRIPTION FACTORS; TRANSFECTION; TRIGLYCERIDES;

EID: 84865039539     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.24207     Document Type: Article

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