Omega-3 fatty acid deficiency augments risperidone-induced hepatic steatosis in rats: Positive association with stearoyl-CoA desaturase

Pharmacological Research

Volumn 66, Issue 4, 2012, Pages 283-291

  McNamara, Robert K ^a   Magrisso, I Jack ^a   Hofacer, Rylon ^a   Jandacek, Ronald ^a   Rider, Therese ^a   Tso, Patrick ^a   Benoit, Stephen C ^a  

^a UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

Author keywords

Atypical antipsychotic; Glucose; Liver; Oleic acid; Omega 3 fatty acids; Polyunsaturated fatty acids; Rat; Risperidone; Stearoyl CoA desaturase 1; Triglycerides

Indexed keywords

ACYL COENZYME A DESATURASE; GLUCOSE; MESSENGER RNA; OMEGA 3 FATTY ACID; OMEGA 6 FATTY ACID; RISPERIDONE; TRIACYLGLYCEROL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; DIETARY INTAKE; DISEASE EXACERBATION; ENZYME ACTIVITY; ESSENTIAL FATTY ACID DEFICIENCY; FATTY ACID BLOOD LEVEL; FATTY LIVER; FLUID INTAKE; FOOD COMPOSITION; FOOD INTAKE; GLUCOSE BLOOD LEVEL; LIPID COMPOSITION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; TRIACYLGLYCEROL BLOOD LEVEL;

ANIMALS; ANTIPSYCHOTIC AGENTS; BLOOD GLUCOSE; DIET; EATING; FATTY ACIDS, OMEGA-3; FATTY LIVER; GENE EXPRESSION REGULATION; LIVER; MALE; RATS; RATS, LONG-EVANS; RISPERIDONE; RNA, MESSENGER; STEAROYL-COA DESATURASE; TRIGLYCERIDES;

EID: 84865029085     PISSN: 10436618     EISSN: 10961186     Source Type: Journal    
DOI: 10.1016/j.phrs.2012.06.010     Document Type: Article

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