Differential effects of antipsychotic medications on polyunsaturated fatty acid biosynthesis in rats: Relationship with liver delta6-desaturase expression

Schizophrenia Research

Volumn 129, Issue 1, 2011, Pages 57-65

  McNamara, Robert K ^a   Jandacek, Ronald ^a   Rider, Therese ^a   Tso, Patrick ^a   Cole Strauss, Allyson ^a,b   Lipton, Jack W ^a,b  

^a UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^b MICHIGAN STATE UNIVERSITY   (United States)

Author keywords

Arachidonic acid; Delta5 desaturase (Fads1); Delta6 desaturase (Fads2); Docosahexaenoic acid; Elongase (Elovl2, Elovl5); Erythrocytes; Frontal cortex; Heart; Plasma; Polyunsaturated fatty acids; Rat

Indexed keywords

ARACHIDONIC ACID; DOCOSAHEXAENOIC ACID; HALOPERIDOL; OLANZAPINE; OMEGA 3 FATTY ACID; OMEGA 6 FATTY ACID; PALIPERIDONE; POLYUNSATURATED FATTY ACID; QUETIAPINE; RISPERIDONE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CHRONIC DRUG ADMINISTRATION; CONTROLLED STUDY; DELTA5 DESATURASE GENE; DELTA6 DESATURASE GENE; ELONGASE 2 GENE; ELONGASE 5 GENE; ERYTHROCYTE; FATTY ACID SYNTHESIS; FRONTAL CORTEX; GENE; GENE EXPRESSION; HEART; LIPID COMPOSITION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; UPREGULATION;

ANIMALS; ANTIPSYCHOTIC AGENTS; BENZODIAZEPINES; DIBENZOTHIAZEPINES; DRINKING WATER; FATTY ACIDS, OMEGA-3; FATTY ACIDS, OMEGA-6; FATTY ACIDS, UNSATURATED; HALOPERIDOL; ISOXAZOLES; LINOLEOYL-COA DESATURASE; LIVER; MALE; PYRIMIDINES; RATS; RATS, LONG-EVANS; RISPERIDONE; RNA, MESSENGER;

EID: 79956143583     PISSN: 09209964     EISSN: 15732509     Source Type: Journal    
DOI: 10.1016/j.schres.2011.03.006     Document Type: Article

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