Arylazolyl(azinyl)thioacetanilide. Part 9#: Synthesis and biological investigation of thiazolylthioacetamides derivatives as a novel class of potential antiviral agents

Archives of Pharmacal Research

Volumn 35, Issue 6, 2012, Pages 975-986

  Zhan, Peng ^a   Wang, Liu ^a   Liu, Hong ^a   Chen, Xuwang ^a   Li, Xiao ^a   Jiang, Xin ^a   Zhang, Qiangqiang ^a   Liu, Xinyong ^a   Pannecouque, Christophe ^b   Naesens, Lieve ^b   De Clercq, Erik ^b   Liu, Ailin ^c   Du, Guanhua ^c  

^a SHANDONG UNIVERSITY   (China)

^b REGA INSTITUTE FOR MEDICAL RESEARCH   (Belgium)

^c INSTITUTE OF MATERIA MEDICA   (China)

Author keywords

Bioactivity; HIV; Influenza virus; NNRTIs; SAR; Synthesis; Thiazolylthioacetamides

Indexed keywords

2 (2 AMINO 4 (2,4 DIBROMOPHENYL)THIAZOL 5 YLTHIO) N (2 BROMOPHENYL)ACETAMIDE; 2 (2 AMINO 4 (2,4 DIBROMOPHENYL)THIAZOL 5 YLTHIO) N (2 CHLOROPHENYL)ACETAMIDE; 2 (2 AMINO 4 (2,4 DIBROMOPHENYL)THIAZOL 5 YLTHIO) N (2 CHLOROPYRIDIN 3 YL)ACETAMIDE; 2 (2 AMINO 4 (2,4 DIBROMOPHENYL)THIAZOL 5 YLTHIO) N (2 FLUOROPHENYL)ACETAMIDE; 2 (2 AMINO 4 (2,4 DIBROMOPHENYL)THIAZOL 5 YLTHIO) N (2 NITROPHENYL)ACETAMIDE; 2 (2 AMINO 4 (2,4 DIBROMOPHENYL)THIAZOL 5 YLTHIO) N (2,4 DICHLOROPHENYL)ACETAMIDE; 2 (2 AMINO 4 (2,4 DIBROMOPHENYL)THIAZOL 5 YLTHIO) N (4 METHYL 2 NITROPHENYL)ACETAMIDE; 2 (2 AMINO 4 (2,4 DIBROMOPHENYL)THIAZOL 5 YLTHIO) N 2 TOLYLACETAMIDE; 2 (2 AMINOCHLORO 4 (2,4 DIBROMOPHENYL)THIAZOL 5 YLTHIO)ACETAMIDE DERIVATIVE; 2 (2 CHLORO 4 (2,4 DIBROMOPHENYL)THIAZOL 5 YLTHIO) N (2 CHLOROPHENYL)ACETAMIDE; 2 (2 CHLORO 4 (2,4 DIBROMOPHENYL)THIAZOL 5 YLTHIO) N (2 CHLOROPYRIDIN 3 YL)ACETAMIDE; 2 (2 CHLORO 4 (2,4 DIBROMOPHENYL)THIAZOL 5 YLTHIO) N (2 FLUOROPHENYL)ACETAMIDE; 2 (2 CHLORO 4 (2,4 DIBROMOPHENYL)THIAZOL 5 YLTHIO) N (2 NITROPHENYL)ACETAMIDE; 2 (2 CHLORO 4 (2,4 DIBROMOPHENYL)THIAZOL 5 YLTHIO) N (2,4 DICHLOROPHENYL)ACETAMIDE; 2 (2 CHLORO 4 (2,4 DIBROMOPHENYL)THIAZOL 5 YLTHIO) N (4 METHYL 2 NITROPHENYL)ACETAMIDE; 2 (2 CHLORO 4 (2,4 DIBROMOPHENYL)THIAZOL 5 YLTHIO) N 2 TOLYLACETAMIDE; ACETANILIDE; AMANTADINE; ANTIVIRUS AGENT; ARYLAZOLYL(AZINYL)THIOACETANILIDE; INFLUENZA VACCINE; N (2 BROMOPHENYL) 2 (2 CHLORO 4 (2,4 DIBROMOPHENYL)THIAZOL 5 YLTHIO)ACETAMIDE; OSELTAMIVIR; RIBAVIRIN; RIMANTADINE; THIAZOLE DERIVATIVE; THIOACETAMIDE DERIVATIVE; UNCLASSIFIED DRUG;

ANTIVIRAL ACTIVITY; ARTICLE; BIOLOGICAL ACTIVITY; DRUG MECHANISM; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN IMMUNODEFICIENCY VIRUS; INFLUENZA A (H1N1); INFLUENZA A (H3N2); INFLUENZA B; NONHUMAN; VIRUS CELL INTERACTION; VIRUS STRAIN;

ANIMALS; ANTI-HIV AGENTS; ANTIVIRAL AGENTS; CHICK EMBRYO; DOGS; DOSE-RESPONSE RELATIONSHIP, DRUG; HIV REVERSE TRANSCRIPTASE; HIV-1; INFLUENZA A VIRUS, H1N1 SUBTYPE; INFLUENZA A VIRUS, H3N2 SUBTYPE; INFLUENZA B VIRUS; INHIBITORY CONCENTRATION 50; MADIN DARBY CANINE KIDNEY CELLS; MOLECULAR STRUCTURE; MUTATION; NEURAMINIDASE; REVERSE TRANSCRIPTASE INHIBITORS; STRUCTURE-ACTIVITY RELATIONSHIP; THIOACETAMIDE;

EID: 84864940620     PISSN: 02536269     EISSN: 19763786     Source Type: Journal    
DOI: 10.1007/s12272-012-0604-y     Document Type: Article

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