Synthesis and anti-HIV activity evaluation of novel N0-arylidene-2-[1- (naphthalen-1-yl)-1H-tetrazol-5-ylthio]acetohydrazides

Medicinal Chemistry Research

Volumn 19, Issue 7, 2010, Pages 652-663

  Zhan, Peng ^a   Liu, Hongbing ^a   Liu, Xinyong ^a   Wang, Yan ^a   Pannecouque, Christophe ^b   Witvrouw, Myriam ^b   De Clercq, Erik ^b  

^a SHANDONG UNIVERSITY   (China)

^b REGA INSTITUTE FOR MEDICAL RESEARCH   (Belgium)

Author keywords

Acetohydrazides; AIDS; Antiviral activity; HIV 1; NNRTIs; Tetrazole

Indexed keywords

ACETOHYDRAZIDE; ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; DELAVIRDINE; EFAVIRENZ; N' (2 CHLOROBENZYLIDENE) 2 [1 (NAPHTHALEN 1 YL) 1H TETRAZOL 5 YLTHIO]ACETOHYDRAZIDE; N' (2 FLUOROBENZYLIDENE) 2 [1 (NAPHTHALEN 1 YL) 1H TETRAZOL 5 YLTHIO]ACETOHYDRAZIDE; N' (2 FURYLMETHYLIDENE) 2 [1 (NAPHTHALEN 1 YL) 1H TETRAZOL 5 YLTHIO]ACETOHYDRAZIDE; N' (2 HYDROXY 5 METHOXYBENZYLIDENE) 2 [1 (NAPHTHALEN 1 YL) 1H TETRAZOL 5 YLTHIO]ACETOHYDRAZIDE; N' (2 HYDROXYBENZYLIDENE) 2 [1 (NAPHTHALEN 1 YL) 1H TETRAZOL 5 YLTHIO]ACETOHYDRAZIDE; N' (2,3 DIMETHOXYBENZYLIDENE) 2 [1 (NAPHTHALEN 1 YL) 1H TETRAZOL 5 YLTHIO]ACETOHYDRAZIDE; N' (2,4 DIMETHOXYBENZYLIDENE) 2 [1 (NAPHTHALEN 1 YL) 1H TETRAZOL 5 YLTHIO]ACETOHYDRAZIDE; N' (3 CHLOROBENZYLIDENE) 2 [1 (NAPHTHALEN 1 YL) 1H TETRAZOL 5 YLTHIO]ACETOHYDRAZIDE; N' (3 HYDROXYBENZYLIDENE) 2 [1 (NAPHTHALEN 1 YL) 1H TETRAZOL 5 YLTHIO]ACETOHYDRAZIDE; N' (3 METHYLBENZYLIDENE) 2 [1 (NAPHTHALEN 1 YL) 1H TETRAZOL 5 YLTHIO]ACETOHYDRAZIDE; N' (3,4 DIMETHOXYBENZYLIDENE) 2 [1 (NAPHTHALEN 1 YL) 1H TETRAZOL 5 YLTHIO]ACETOHYDRAZIDE; N' (4 CHLOROBENZYLIDENE) 2 [1 (NAPHTHALEN 1 YL) 1H TETRAZOL 5 YLTHIO]ACETOHYDRAZIDE; N' (4 FLUOROBENZYLIDENE) 2 [1 (NAPHTHALEN 1 YL) 1H TETRAZOL 5 YLTHIO]ACETOHYDRAZIDE; N' (4 HYDROXY 3 METHOXYBENZYLIDENE) 2 [1 (NAPHTHALEN 1 YL) 1H TETRAZOL 5 YLTHIO]ACETOHYDRAZIDE; N' (4 HYDROXYBENZYLIDENE) 2 [1 (NAPHTHALEN 1 YL) 1H TETRAZOL 5 YLTHIO]ACETOHYDRAZIDE; N' (4 METHOXYBENZYLIDENE) 2 [1 (NAPHTHALEN 1 YL) 1H TETRAZOL 5 YLTHIO]ACETOHYDRAZIDE; N' (4 NITROBENZYLIDENE) 2 [1 (NAPHTHALEN 1 YL) 1H TETRAZOL 5 YLTHIO]ACETOHYDRAZIDE; N' [4 (DIMETHYLAMINO)BENZYLIDENE] 2 [1 (NAPHTHALEN 1 YL) 1H TETRAZOL 5 YLTHIO]ACETOHYDRAZIDE; N' BENZYLIDENE 2 [1 (NAPHTHALEN 1 YL) 1H TETRAZOL 5 YLTHIO]ACETOHYDRAZIDE; NEVIRAPINE; NONNUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITOR; UNCLASSIFIED DRUG; ZIDOVUDINE;

ANTIVIRAL ACTIVITY; ARTICLE; CYTOTOXICITY; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 2; IN VITRO STUDY; VIRUS REPLICATION;

EID: 77956478098     PISSN: 10542523     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00044-009-9220-x     Document Type: Article

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