Hippocampal neurogenesis, cognitive Deficits and affective disorDer in huntington's disease

Neural Plasticity

Volumn 2012, Issue , 2012, Pages

  Ransome, Mark I ^a   Renoir, Thibault ^a   Hannan, Anthony J ^a  

^a UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ANDROGEN RECEPTOR; BRAIN DERIVED NEUROTROPHIC FACTOR; FLUOXETINE; NEUROTROPHIN; SEROTONIN; SERTRALINE; TESTOSTERONE;

AFFECT; ANDROGEN THERAPY; BEHAVIOR CHANGE; BRAIN SIZE; CELL PROLIFERATION; CELL SURVIVAL; COGNITION; COGNITIVE DEFECT; DRUG EFFICACY; EMOTIONAL DISORDER; GENE MUTATION; HIPPOCAMPUS; HUMAN; HUNTINGTON CHOREA; IN VIVO STUDY; MAJOR DEPRESSION; MOOD DISORDER; MOTOR DYSFUNCTION; NERVE CELL DIFFERENTIATION; NERVE CELL PLASTICITY; NERVOUS SYSTEM DEVELOPMENT; NEUROTRANSMISSION; NONHUMAN; PROTEIN EXPRESSION; REVIEW; SEROTONINERGIC SYSTEM; SEX DIFFERENCE; TESTIS FUNCTION; YEAST ARTIFICIAL CHROMOSOME; ANIMAL; DISEASE MODEL; GROWTH, DEVELOPMENT AND AGING; MOUSE; PATHOLOGY; PHYSIOLOGY; PSYCHOLOGICAL ASPECT; TRANSGENIC MOUSE;

ANIMALS; COGNITION DISORDERS; DISEASE MODELS, ANIMAL; HIPPOCAMPUS; HUMANS; HUNTINGTON DISEASE; MICE; MICE, TRANSGENIC; MOOD DISORDERS; NEUROGENESIS; NEURONAL PLASTICITY;

EID: 84864922220     PISSN: 20905904     EISSN: 16875443     Source Type: Journal    
DOI: 10.1155/2012/874387     Document Type: Review

References (70)

1. Jones E. G., The neuron doctrine 1891 Journal of the History of the Neurosciences 1994 3 1 3 20
2. Berlucchi G., Buchtel H. A., Neuronal plasticity: historical roots and evolution of meaning Experimental Brain Research 2009 192 3 307 319
3. Altman J., Are new neurons formed in the brains of adult mammals? Science 1962 135 3509 1127 1128
4. Altman J., Das G. D., Autoradiographic and histological eviDence of postnatal hippocampal neurogenesis in rats Journal of Comparative Neurology 1965 124 3 319 335
5. Gross C. G., Neurogenesis in the adult brain: death of a dogma Nature Reviews Neuroscience 2000 1 1 67 73
6. Marchetto M. C. N., Winner B., Gage F. H., Pluripotent stem cells in neurodegenerative and neuroDevelopmental diseases Human Molecular Genetics 2010 19 1 R71 R76
7. Gil-Mohapel J., Simpson J. M., Ghilan M., Christie B. R., Neurogenesis in Huntington's disease: can studying adult neurogenesis lead to the Development of new therapeutic strategies? Brain Research 2011 1406 84 105
8. Squire L. R., Memory and the hippocampus: a synthesis from findings with rats, monkeys, and humans Psychological Review 1992 99 2 195 231
9. Nestler E. J., Barrot M., DiLeone R. J., Eisch A. J., Gold S. J., Monteggia L. M., Neurobiology of depression Neuron 2002 34 1 13 25 (Pubitemid 34270695)
10. Pittenger C., Duman R. S., Stress, depression, and neuroplasticity: a convergence of mechanisms Neuropsychopharmacology 2008 33 1 88 109 (Pubitemid 350191319)
11. Phillips W., Shannon K. M., Barker R. A., The current clinical management of Huntington's disease Movement DisorDers 2008 23 11 1491 1504
12. Eriksson P. S., Perfilieva E., Bjrk-Eriksson T., Alborn A. M., Nordborg C., Peterson D. A., Gage F. H., Neurogenesis in the adult human hippocampus Nature Medicine 1998 4 11 1313 1317 (Pubitemid 28512114)
13. Lucassen P. J., Meerlo P., Naylor A. S., Van Dam A. M., Dayer A. G., Fuchs E., Oomen C. A., Czéh B., Regulation of adult neurogenesis by stress, sleep disruption, exercise and inflammation: implications for depression and antidepressant action European Neuropsychopharmacology 2010 20 1 1 17
14. Drew M. R., Hen R., Adult hippocampal neurogenesis as target for the treatment of depression CNS and Neurological DisorDers Drug Targets 2007 6 3 205 218 (Pubitemid 46916252)
15. Duman R. S., Malberg J., Thome J., Neural plasticity to stress and antidepressant treatment Biological Psychiatry 1999 46 9 1181 1191 (Pubitemid 30114436)
16. Jacobs B. L., Van Praag H., Gage F. H., Adult brain neurogenesis and psychiatry: a novel theory of depression Molecular Psychiatry 2000 5 3 262 269 (Pubitemid 30438401)
17. Deng W., Aimone J. B., Gage F. H., New neurons and new memories: how does adult hippocampal neurogenesis affect learning and memory? Nature Reviews Neuroscience 2010 11 5 339 350
18. Murphy K. P. S. J., Carter R. J., Lione L. A., Mangiarini L., Mahal A., Bates G. P., Dunnett S. B., Jennifer Morton A., Abnormal synaptic plasticity and impaired spatial cognition in mice transgenic for exon 1 of the human Huntington's disease mutation Neuroscience 2000 20 13 5115 5123 (Pubitemid 30421714)
19. Nithianantharajah J., Barkus C., Murphy M., Hannan A. J., Gene-environment interactions modulating cognitive function and molecular correlates of synaptic plasticity in Huntington's disease transgenic mice Neurobiology of Disease 2008 29 3 490 504
20. Pang T. Y. C., Stam N. C., Nithianantharajah J., Howard M. L., Hannan A. J., Differential effects of voluntary physical exercise on behavioral and brain-Derived neurotrophic factor expression Deficits in huntington's disease transgenic mice Neuroscience 2006 141 2 569 584 (Pubitemid 44066652)
21. Pang T. Y. C., Du X., Zajac M. S., Howard M. L., Hannan A. J., Altered serotonin receptor expression is associated with depression-related behavior in the R6/1 transgenic mouse model of Huntington's disease Human Molecular Genetics 2009 18 4 753 766
22. Renoir T., Zajac M. S., Du X., Pang T. Y., Leang L., Chevarin C., Lanfumey L., Hannan A. J., Sexually dimorphic serotonergic dysfunction in a mouse model of Huntington's disease and depression PLoS ONE 2011 6 7, article e22133
23. Mandrioli R., Mercolini L., Saracino M. A., Raggi M. A., Selective serotonin reuptake inhibitors (SSRIs): therapeutic drug monitoring and pharmacological interactions Current Medicinal Chemistry 2012 19 12 1846 1863
24. Rocha F. L., Fuzikawa C., Riera R., Hara C., Combination of antidepressants in the treatment of major depressive disorDer: a systematic review and meta-analysis Journal of Clinical Psychopharmacology 2012 32 2 278 281
25. Grote H. E., Bull N. D., Howard M. L., Van Dellen A., Blakemore C., Bartlett P. F., Hannan A. J., Cognitive disorDers and neurogenesis Deficits in Huntington's disease mice are rescued by fluoxetine European Journal of Neuroscience 2005 22 8 2081 2088 (Pubitemid 41579396)
26. Lazic S. E., Grote H., Armstrong R. J. E., Blakemore C., Hannan A. J., Van Dellen A., Barker R. A., Decreased hippocampal cell proliferation in R6/I Huntington's mice NeuroReport 2004 15 5 811 813 (Pubitemid 38453463)
27. Lazic S. E., Grote H. E., Blakemore C., Hannan A. J., Van Dellen A., Phillips W., Barker R. A., Neurogenesis in the R6/1 transgenic mouse model of Huntington's disease: effects of environmental enrichment European Journal of Neuroscience 2006 23 7 1829 1838
28. Walker T. L., Turnbull G. W., Mackay E. W., Hannan A. J., Bartlett P. F., The latent stem cell population is retained in the hippocampus of transgenic Huntington's disease mice but not wild-type mice PLoS ONE 2011 6 3, article e18153
29. Gil J. M. A. C., Mohapel P., Arajo I. M., Popovic N., Li J. Y., Brundin P., Petersén., Reduced hippocampal neurogenesis in R6/2 transgenic Huntington's disease mice Neurobiology of Disease 2005 20 3 744 751 (Pubitemid 41619351)
30. Phillips W., Morton A. J., Barker R. A., Abnormalities of neurogenesis in the R6/2 mouse model of Huntington's disease are attributable to the in vivo microenvironment Neuroscience 2005 25 50 11564 11576 (Pubitemid 43098449)
31. Peng Q., Masuda N., Jiang M., Li Q., Zhao M., Ross C. A., Duan W., The antidepressant sertraline improves the phenotype, promotes neurogenesis and increases BDNF levels in the R6/2 Huntington's disease mouse model Experimental Neurology 2008 210 1 154 163
32. Renoir T., Pang T. Y. C., Zajac M., Chan G., Du X., Leang L., Chevarin C., Lanfumey L., Hannan A. J., Treatment of depressive-like behaviour in Huntington's disease mice by chronic sertraline and exercise British Journal of Pharmacology 2012 165 5 1375 1389
33. Klempin F., Babu H., Tonelli D. D. P., Alarcon E, Fabel K., Kempermann G., Oppositional effects of serotonin receptors 5-HT1a, 2, and 2c in the regulation of adult hippocampal neurogenesis Frontiers in Molecular Neuroscience 2010 3 14
34. Renoir T., Chevarin C., Lanfumey-Mongredien L., Hannan A. J., Effect of enhanced voluntary physical exercise on brain levels of monoamines in Huntington disease mice PLoS Currents 2011 3, article RRN1281
35. Hodgson J. G., Agopyan N., Gutekunst C. A., Leavitt B. R., Lepiane F., Singaraja R., Smith D. J., Bissada N., McCutcheon K., Nasir J., Jamot L., Xiao-Jiang L., Stevens M. E., Rosemond E., RoDer J. C., Phillips A. G., Rubin E. M., Hersch S. M., HayDen M. R., A YAC mouse model for Huntington's disease with full-length mutant huntingtin, cytoplasmic toxicity, and selective striatal neurodegeneration Neuron 1999 23 1 181 192 (Pubitemid 29262475)
36. Van Raamsdonk J. M., Pearson J., Slow E. J., Hossain S. M., Leavitt B. R., HayDen M. R., Cognitive dysfunction precedes neuropathology and motor abnormalities in the YAC128 mouse model of Huntington's disease Neuroscience 2005 25 16 4169 4180 (Pubitemid 40563393)
37. Pouladi M. A., Graham R. K., Karasinska J. M., Xie Y., Santos R. D., Petersn D., HayDen M. R., Prevention of depressive behaviour in the YAC128 mouse model of Huntington disease by mutation at residue 586 of huntingtin Brain 2009 132 part 4 919 932
38. Ernst C., Olson A. K., Pinel J. P. J., Lam R. W., Christie B. R., Antidepressant effects of exercise: eviDence for an adult-neurogenesis hypothesis? Journal of Psychiatry and Neuroscience 2006 31 2 84 92
39. Simpson J. M., Gil-Mohapel J., Pouladi M. A., Ghilan M., Xie Y., HayDen M. R., Christie B. R., Altered adult hippocampal neurogenesis in the YAC128 transgenic mouse model of Huntington disease Neurobiology of Disease 2011 41 2 249 260
40. Orvoen S., Pla P., Gardier A. M., Saudou F., David D. J., Huntington's disease knock-in male mice show specific anxiety-like behaviour and altered neuronal maturation Neuroscience Letters 2012 507 2 127 132
41. Van Praag H., Christie B. R., Sejnowski T. J., Gage F. H., Running enhances neurogenesis, learning, and long-term potentiation in mice Proceedings of the National Academy of Sciences of the United States of America 1999 96 23 13427 13431
42. Bjrnebekk A., Mathé A. A., Brené S., The antidepressant effect of running is associated with increased hippocampal cell proliferation International Journal of Neuropsychopharmacology 2005 8 3 357 368 (Pubitemid 41002490)
43. Van Dellen A., Blakemore C., Deacon R., York D., Hannan A. J., delaying the onset of Huntington's in mice Nature 2000 404 6779 721 722 (Pubitemid 30212388)
44. Low V. F., Dragunow M., Tippett L. J., Faull R. L. M., Curtis M. A., No change in progenitor cell proliferation in the hippocampus in Huntington's disease Neuroscience 2011 199 577 588
45. Spargo E., Everall I. P., Lantos P. L., Neuronal loss in the hippocampus in Huntington's disease: a comparison with HIV infection Journal of Neurology Neurosurgery and Psychiatry 1993 56 5 487 491 (Pubitemid 23171778)
46. Bohanna I., Georgiou-Karistianis N., Hannan A. J., Egan G. F., Magnetic resonance imaging as an approach towards iDentifying neuropathological biomarkers for Huntington's disease Brain Research Reviews 2008 58 1 209 225
47. Spires T. L., Grote H. E., Garry S., CorDery P. M., Van Dellen A., Blakemore C., Hannan A. J., Dendritic spine pathology and Deficits in experience-depenDent Dendritic plasticity in R6/1 Huntington's disease transgenic mice European Journal of Neuroscience 2004 19 10 2799 2807 (Pubitemid 38746396)
48. Zajac M. S., Pang T. Y. C., Wong N., Weinrich B., Leang L. S. K., Craig J. M., Saffery R., Hannan A. J., Wheel running and environmental enrichment differentially modify exon-specific BDNF expression in the hippocampus of wild-type and pre-motor symptomatic male and female Huntington's disease mice Hippocampus 2010 20 5 621 636
49. Zigova T., Pencea V., Wiegand S. J., Luskin M. B., Intraventricular administration of BDNF increases the number of newly generated neurons in the adult olfactory bulb Molecular and Cellular Neurosciences 1998 11 4 234 245 (Pubitemid 28361411)
50. Benraiss A., Chmielnicki E., Lerner K., Roh D., Goldman S. A., ADenoviral brain-Derived neurotrophic factor induces both neostriatal and olfactory neuronal recruitment from endogenous progenitor cells in the adult forebrain Neuroscience 2001 21 17 6718 6731 (Pubitemid 32781116)
51. Zuccato C., Cattaneo E., Brain-Derived neurotrophic factor in neurodegenerative diseases Nature Reviews Neurology 2009 5 6 311 322
52. Bekinschtein P., Oomen C. A., Saksida L. M., Bussey T. J., Effects of environmental enrichment and voluntary exercise on neurogenesis, learning and memory, and pattern separation: BDNF as a critical variable? Seminars in Cell and Developmental Biology 2011 22 5 536 542
53. Nagahara A. H., Tuszynski M. H., Potential therapeutic uses of BDNF in neurological and psychiatric disorDers Nature Reviews Drug Discovery 2011 10 3 209 219
54. Grigoriadis S., Robinson G. E., GenDer issues in depression Annals of Clinical Psychiatry 2007 19 4 247 255 (Pubitemid 350208795)
55. Marcus S. M., Young E. A., Kerber K. B., Kornstein S., Farabaugh A. H., Mitchell J., Wisniewski S. R., Balasubramani G. K., Trivedi M. H., Rush A. J., GenDer differences in depression: findings from the STARD study Journal of Affective DisorDers 2005 87 2-3 141 150 (Pubitemid 41039936)
56. Galea L. A. M., Gonadal hormone modulation of neurogenesis in the Dentate gyrus of adult male and female roDents Brain Research Reviews 2008 57 2 332 341 (Pubitemid 351381762)
57. Hodes G. E., Hill-Smith T. E., Suckow R. F., Cooper T. B., Lucki I., Sex-specific effects of chronic fluoxetine treatment on neuroplasticity and pharmacokinetics in mice Journal of Pharmacology and Experimental Therapeutics 2010 332 1 266 273
58. Manning E. E., Ransome M. I., Burrows E. L., Hannan A. J., Increased adult hippocampal neurogenesis and abnormal migration of adult-born granule neurons is associated with hippocampal-specific cognitive Deficits in phospholipase C- 1 knockout mice Hippocampus 2012 22 2 309 319
59. Majerov V., Kalink T., Lacz J., Vyhnlek M., Hort J., Bojar M., Rika E., Roth J., Disturbance of real space navigation in moDerately adVanced but not in early Huntington's disease Journal of the Neurological Sciences 2012 312 1-2 86 91
60. Almeida O. P., Yeap B. B., Hankey G. J., Jamrozik K., Flicker L., Low free testosterone concentration as a potentially treatable cause of depressive symptoms in olDer men Archives of General Psychiatry 2008 65 3 283 289 (Pubitemid 351342444)
61. Markianos M., Panas M., Kalfakis N., Vassilopoulos D., Plasma testosterone in male patients with Huntington's disease: relations to severity of illness and dementia Annals of Neurology 2005 57 4 520 525 (Pubitemid 40471161)
62. Hannan A. J., Ransome M. I., Deficits in spermatogenesis but not neurogenesis are alleviated by chronic testosterone therapy in R6/1 Huntington's disease mice Journal of Neuroendocrinology 2012 24 2 341 356
63. Clelland C. D., Choi M., Romberg C., Clemenson G. D., Fragniere A., Tyers P., Jessberger S., Saksida L. M., Barker R. A., Gage F. H., Bussey T. J., A functional role for adult hippocampal neurogenesis in spatial pattern separation Science 2009 325 5937 210 213
64. Malberg J. E., Eisch A. J., Nestler E. J., Duman R. S., Chronic antidepressant treatment increases neurogenesis in adult rat hippocampus Neuroscience 2000 20 24 9104 9110 (Pubitemid 32042912)
65. Santarelli L., Saxe M., Gross C., Surget A., Battaglia F., Dulawa S., Weisstaub N., Lee J., Duman R., Arancio O., Belzung C., Hen R., Requirement of hippocampal neurogenesis for the behavioral effects of antidepressants Science 2003 301 5634 805 809 (Pubitemid 36962615)
66. Kempermann G., Krebs J., Fabel K., The contribution of failing adult hippocampal neurogenesis to psychiatric disorDers Current Opinion in Psychiatry 2008 21 3 290 295 (Pubitemid 351489351)
67. Jans L. A. W., Riedel W. J., Markus C. R., Blokland A., Serotonergic vulnerability and depression: assumptions, experimental eviDence and implications Molecular Psychiatry 2007 12 6 522 543 (Pubitemid 46816766)
68. Milnerwood A. J., Raymond L. A., Early synaptic pathophysiology in neurodegeneration: insights from Huntington's disease Trends in Neurosciences 2010 33 11 513 523
69. Raymond L. A., André V. M., Cepeda C., Gladding C. M., Milnerwood A. J., Levine M. S., Pathophysiology of Huntington's disease: time-depenDent alterations in synaptic and receptor function Neuroscience 2011 198 252 273
70. Nithianantharajah J., Hannan A. J., Dysregulation of synaptic proteins, Dendritic spine abnormalities and pathological plasticity of synapses as experience-depenDent mediators of cognitive and psychiatric symptoms in Huntingtons disease. Neuroscience. In press