Anomalous dispersion analysis of inhibitor flexibility: A case study of the kinase inhibitor H-89

Acta Crystallographica Section F: Structural Biology and Crystallization Communications

Volumn 68, Issue 8, 2012, Pages 873-877

  Pflug, Alexander ^a   Johnson, Kenneth A ^a   Engh, Richard A ^a  

^a UNIVERSITY OF TROMSØ   (Norway)

Author keywords

anomalous dispersion; bromine; flexibility; inhibitors; kinases; ligands; protein kinase A; SAD

Indexed keywords

CYCLIC AMP DEPENDENT PROTEIN KINASE; ISOQUINOLINE DERIVATIVE; N (2 (4 BROMOCINNAMYLAMINO)ETHYL) 5 ISOQUINOLINESULFONAMIDE; N-(2-(4-BROMOCINNAMYLAMINO)ETHYL)-5-ISOQUINOLINESULFONAMIDE; PROTEIN KINASE INHIBITOR; SULFONAMIDE;

ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; HUMAN; PROTEIN DOMAIN;

CYCLIC AMP-DEPENDENT PROTEIN KINASES; HUMANS; ISOQUINOLINES; MODELS, MOLECULAR; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEIN KINASE INHIBITORS; SULFONAMIDES;

EID: 84864881134     PISSN: None     EISSN: 17443091     Source Type: Journal    
DOI: 10.1107/S1744309112028655     Document Type: Article

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