X-ray crystallographic studies of serotonin N-acetyltransferase catalysis and inhibition

Journal of Molecular Biology

Volumn 317, Issue 2, 2002, Pages 215-224

  Wolf, Eva ^a   De Angelis, Jacqueline ^a   Khalil, Ehab M ^a   Cole, Philip A ^a   Burley, Stephen K ^a  

^a ROCKEFELLER UNIVERSITY   (United States)

Author keywords

Alternate conformations; Bisubstrate analog inhibitor; GCN5 related N acetyltransferase; Melatonin biosynthesis; Serotonin N acetyltransferase

Indexed keywords

ACETYL COENZYME A; ACYLTRANSFERASE; ACYLTRANSFERASE INHIBITOR; SEROTONIN N ACETYLTRANSFERASE; TRYPTAMINE DERIVATIVE;

AMINO ACID SEQUENCE; ANALYTIC METHOD; ARTICLE; BINDING SITE; BROMINATION; CATALYSIS; CONTROLLED STUDY; CRYSTAL STRUCTURE; DIFFRACTION; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME CONFORMATION; ENZYME INHIBITION; ENZYME MECHANISM; ENZYME SUBSTRATE; ENZYME SUBSTRATE COMPLEX; NONHUMAN; PHYLOGENY; PRIORITY JOURNAL; PROTEIN FAMILY; PROTEIN MOTIF; TRANS ISOMER; X RAY CRYSTALLOGRAPHY;

DIPTERA;

EID: 0036299021     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.2001.5371     Document Type: Article

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