-
2
-
-
43449114782
-
Pancreatic carcinogenesis
-
DOI 10.1159/000123838
-
Koorstra, J.B., Hustinx, S.R., Offerhaus, G.J. & Maitra, A. Pancreatic carcinogenesis. Pancreatology 8, 110-125 (2008). (Pubitemid 351670364)
-
(2008)
Pancreatology
, vol.8
, Issue.2
, pp. 110-125
-
-
Koorstra, J.-B.M.1
Hustinx, S.R.2
Offerhaus, G.J.A.3
Maitra, A.4
-
3
-
-
34547160717
-
Biology and management of pancreatic cancer
-
DOI 10.1136/gut.2006.103333
-
Ghaneh, P., Costello, E. & Neoptolemos, J.P. Biology and management of pancreatic cancer. Gut 56, 1134-1152 (2007). (Pubitemid 47123247)
-
(2007)
Gut
, vol.56
, Issue.8
, pp. 1134-1152
-
-
Ghaneh, P.1
Costello, E.2
Neoptolemos, J.P.3
-
4
-
-
67650874081
-
Cancer statistics, 2009
-
Jemal, A. et al. Cancer statistics, 2009. CA Cancer J. Clin. 59, 225-249 (2009).
-
(2009)
CA Cancer J. Clin.
, vol.59
, pp. 225-249
-
-
Jemal, A.1
-
5
-
-
80051557189
-
The promise of a personalized genomic approach to pancreatic cancer and why targeted therapies have missed the mark
-
Fisher, W.E. The promise of a personalized genomic approach to pancreatic cancer and why targeted therapies have missed the mark. World J. Surg. 35, 1766-1769 (2011).
-
(2011)
World J. Surg.
, vol.35
, pp. 1766-1769
-
-
Fisher, W.E.1
-
6
-
-
0017362792
-
15/17 Translocation, a consistent chromosomal change in acute promyelocytic leukaemia
-
Rowley, J.D., Golomb, H.M. & Dougherty, C. 15/17 translocation, a consistent chromosomal change in acute promyelocytic leukaemia. Lancet 1, 549-550 (1977). (Pubitemid 8045927)
-
(1977)
Lancet
, vol.1
, Issue.8010
, pp. 549-550
-
-
Rowley, J.D.1
Golomb, H.M.2
Dougherty, C.3
-
7
-
-
0017758445
-
Further evidence for a non-random chromosomal abnormality in acute promyelocytic leukemia
-
Rowley, J.D. et al. Further evidence for a non-random chromosomal abnormality in acute promyelocytic leukemia. Int.J. Cancer 20, 869-872 (1977). (Pubitemid 8235944)
-
(1977)
International Journal of Cancer
, vol.20
, Issue.6
, pp. 869-872
-
-
Rowley, J.D.1
Golomb, H.M.2
Vardiman, J.3
-
8
-
-
7244245762
-
Finishing the euchromatic sequence of the human genome
-
International Human Genome Sequencing Consortium.
-
International Human Genome Sequencing Consortium. Finishing the euchromatic sequence of the human genome. Nature 431, 931-945 (2004).
-
(2004)
Nature
, vol.431
, pp. 931-945
-
-
-
9
-
-
79951475133
-
A decade's perspective on DNA sequencing technology
-
Mardis, E.R. A decade's perspective on DNA sequencing technology. Nature 470, 198-203 (2011).
-
(2011)
Nature
, vol.470
, pp. 198-203
-
-
Mardis, E.R.1
-
10
-
-
55549101623
-
DNA sequencing of a cytogenetically normal acute myeloid leukaemia genome
-
Ley, T.J. et al. DNA sequencing of a cytogenetically normal acute myeloid leukaemia genome. Nature 456, 66-72 (2008).
-
(2008)
Nature
, vol.456
, pp. 66-72
-
-
Ley, T.J.1
-
11
-
-
79955038968
-
Use of whole-genome sequencing to diagnose a cryptic fusion oncogene
-
Welch, J.S. et al. Use of whole-genome sequencing to diagnose a cryptic fusion oncogene. JAMA 305, 1577-1584 (2011).
-
(2011)
JAMA
, vol.305
, pp. 1577-1584
-
-
Welch, J.S.1
-
12
-
-
82655184653
-
Personalized oncology through integrative high-throughput sequencing: A pilot study
-
Roychowdhury, S. et al. Personalized oncology through integrative high-throughput sequencing: a pilot study. Sci. Transl. Med. 3, 111ra121 (2011).
-
(2011)
Sci. Transl. Med.
, vol.3
-
-
Roychowdhury, S.1
-
15
-
-
24044455869
-
Genome sequencing in microfabricated high-density picolitre reactors
-
DOI 10.1038/nature03959, PII N03959
-
Margulies, M. et al. Genome sequencing in microfabricated high-density picolitre reactors. Nature 437, 376-380 (2005). (Pubitemid 41613494)
-
(2005)
Nature
, vol.437
, Issue.7057
, pp. 376-380
-
-
Margulies, M.1
Egholm, M.2
Altman, W.E.3
Attiya, S.4
Bader, J.S.5
Bemben, L.A.6
Berka, J.7
Braverman, M.S.8
Chen, Y.-J.9
Chen, Z.10
Dewell, S.B.11
Du, L.12
Fierro, J.M.13
Gomes, X.V.14
Godwin, B.C.15
He, W.16
Helgesen, S.17
Ho, C.H.18
Irzyk, G.P.19
Jando, S.C.20
Alenquer, M.L.I.21
Jarvie, T.P.22
Jirage, K.B.23
Kim, J.-B.24
Knight, J.R.25
Lanza, J.R.26
Leamon, J.H.27
Lefkowitz, S.M.28
Lei, M.29
Li, J.30
Lohman, K.L.31
Lu, H.32
Makhijani, V.B.33
McDade, K.E.34
McKenna, M.P.35
Myers, E.W.36
Nickerson, E.37
Nobile, J.R.38
Plant, R.39
Puc, B.P.40
Ronan, M.T.41
Roth, G.T.42
Sarkis, G.J.43
Simons, J.F.44
Simpson, J.W.45
Srinivasan, M.46
Tartaro, K.R.47
Tomasz, A.48
Vogt, K.A.49
Volkmer, G.A.50
Wang, S.H.51
Wang, Y.52
Weiner, M.P.53
Yu, P.54
Begley, R.F.55
Rothberg, J.M.56
more..
-
16
-
-
52949096084
-
Next-generation DNA sequencing methods
-
Mardis, E.R. Next-generation DNA sequencing methods. Annu. Rev. Genomics Hum. Genet. 9, 387-402 (2008).
-
(2008)
Annu. Rev. Genomics Hum. Genet.
, vol.9
, pp. 387-402
-
-
Mardis, E.R.1
-
17
-
-
84856565531
-
SomaticSniper: Identification of somatic point mutations in whole genome sequencing data
-
Larson, D.E. et al. SomaticSniper: identification of somatic point mutations in whole genome sequencing data. Bioinformatics 28, 311-317 (2012).
-
(2012)
Bioinformatics
, vol.28
, pp. 311-317
-
-
Larson, D.E.1
-
18
-
-
69549116107
-
BreakDancer: An algorithm for high-resolution mapping of genomic structural variation
-
Chen, K. et al. BreakDancer: an algorithm for high-resolution mapping of genomic structural variation. Nat. Methods 6, 677-681 (2009).
-
(2009)
Nat. Methods
, vol.6
, pp. 677-681
-
-
Chen, K.1
-
19
-
-
79961007031
-
CREST maps somatic structural variation in cancer genomes with base-pair resolution
-
Wang, J. et al. CREST maps somatic structural variation in cancer genomes with base-pair resolution. Nat. Methods 8, 652-654 (2011).
-
(2011)
Nat. Methods
, vol.8
, pp. 652-654
-
-
Wang, J.1
-
20
-
-
84863229597
-
VarScan 2: Somatic mutation and copy number alteration discovery in cancer by exome sequencing
-
Koboldt, D.C. et al. VarScan 2: Somatic mutation and copy number alteration discovery in cancer by exome sequencing. Genome Res. 22, 568-576 (2012).
-
(2012)
Genome Res.
, vol.22
, pp. 568-576
-
-
Koboldt, D.C.1
-
21
-
-
84862776906
-
Clonal evolution in relapsed acute myeloid leukaemia revealed by whole-genome sequencing
-
Ding, L. et al. Clonal evolution in relapsed acute myeloid leukaemia revealed by whole-genome sequencing. Nature 481, 506-510 (2012).
-
(2012)
Nature
, vol.481
, pp. 506-510
-
-
Ding, L.1
-
22
-
-
84863393080
-
Intratumor heterogeneity and branched evolution revealed by multiregion sequencing
-
Gerlinger, M. et al. Intratumor heterogeneity and branched evolution revealed by multiregion sequencing.N. Engl.J. Med. 366, 883-892 (2012).
-
(2012)
N. Engl.J. Med.
, vol.366
, pp. 883-892
-
-
Gerlinger, M.1
-
23
-
-
79953766940
-
Tumour evolution inferred by single-cell sequencing
-
Navin, N. et al. Tumour evolution inferred by single-cell sequencing. Nature 472, 90-94 (2011).
-
(2011)
Nature
, vol.472
, pp. 90-94
-
-
Navin, N.1
-
24
-
-
35748951614
-
Direct selection of human genomic loci by microarray hybridization
-
DOI 10.1038/nmeth1111, PII NMETH1111
-
Albert, T.J. et al. Direct selection of human genomic loci by microarray hybridization. Nat. Methods 4, 903-905 (2007). (Pubitemid 350042375)
-
(2007)
Nature Methods
, vol.4
, Issue.11
, pp. 903-905
-
-
Albert, T.J.1
Molla, M.N.2
Muzny, D.M.3
Nazareth, L.4
Wheeler, D.5
Song, X.6
Richmond, T.A.7
Middle, C.M.8
Rodesch, M.J.9
Packard, C.J.10
Weinstock, G.M.11
Gibbs, R.A.12
-
25
-
-
36549021060
-
Genome-wide in situ exon capture for selective resequencing
-
DOI 10.1038/ng.2007.42, PII NG200742
-
Hodges, E. et al. Genome-wide in situ exon capture for selective resequencing. Nat. Genet. 39, 1522-1527 (2007). (Pubitemid 350191350)
-
(2007)
Nature Genetics
, vol.39
, Issue.12
, pp. 1522-1527
-
-
Hodges, E.1
Xuan, Z.2
Balija, V.3
Kramer, M.4
Molla, M.N.5
Smith, S.W.6
Middle, C.M.7
Rodesch, M.J.8
Albert, T.J.9
Hannon, G.J.10
McCombie, W.R.11
-
26
-
-
59849113821
-
Solution hybrid selection with ultra-long oligonucleotides for massively parallel targeted sequencing
-
Gnirke, A. et al. Solution hybrid selection with ultra-long oligonucleotides for massively parallel targeted sequencing. Nat. Biotechnol. 27, 182-189 (2009).
-
(2009)
Nat. Biotechnol.
, vol.27
, pp. 182-189
-
-
Gnirke, A.1
-
27
-
-
79955550445
-
A user's guide to the encyclopedia of DNA elements (ENCODE)
-
Myers, R.M. et al. A user's guide to the encyclopedia of DNA elements (ENCODE). PLoS Biol. 9, e1001046 (2011).
-
(2011)
PLoS Biol.
, vol.9
-
-
Myers, R.M.1
-
28
-
-
84858126071
-
MicroRNA dysregulation in cancer: Diagnostics, monitoring and therapeutics
-
Iorio, M.V. & Croce, C.M. MicroRNA dysregulation in cancer: diagnostics, monitoring and therapeutics. A comprehensive review. EMBO Mol. Med. 4, 143-159 (2012).
-
(2012)
A Comprehensive Review. EMBO Mol. Med.
, vol.4
, pp. 143-159
-
-
Iorio, M.V.1
Croce, C.M.2
-
29
-
-
70349969478
-
Mutational evolution in a lobular breast tumour profiled at single nucleotide resolution
-
Shah, S.P. et al. Mutational evolution in a lobular breast tumour profiled at single nucleotide resolution. Nature 461, 809-813 (2009).
-
(2009)
Nature
, vol.461
, pp. 809-813
-
-
Shah, S.P.1
-
30
-
-
84872498738
-
-
International Cancer Genome Consortium
-
International Cancer Genome Consortium. ICGC cancer genome projects [online], www.icgc.org (2012).
-
(2012)
ICGC Cancer Genome Projects
-
-
-
31
-
-
80051547657
-
-
National Cancer Institute
-
National Cancer Institute. The cancer genome atlas [online], http://cancergenome.nih.gov (2012).
-
(2012)
The Cancer Genome Atlas
-
-
-
32
-
-
84872502274
-
-
International Cancer Genome Consortium
-
International Cancer Genome Consortium. Pancreatic cancer-ductal adenocarcinoma [online], http://www.icgc.org/icgc/cgp/68/304/798 (2011).
-
(2011)
Pancreatic Cancer-ductal Adenocarcinoma
-
-
-
34
-
-
77955293476
-
Evolution of an adenocarcinoma in response to selection by targeted kinase inhibitors
-
Jones, S.J. et al. Evolution of an adenocarcinoma in response to selection by targeted kinase inhibitors. Genome Biol. 11, R82 (2010).
-
(2010)
Genome Biol.
, vol.11
-
-
Jones, S.J.1
-
35
-
-
78651330430
-
COSMIC: Mining complete cancer genomes in the Catalogue of Somatic Mutations in Cancer
-
Forbes, S.A. et al. COSMIC: mining complete cancer genomes in the Catalogue of Somatic Mutations in Cancer. Nucleic Acids Res. 39, D945-D950 (2011).
-
(2011)
Nucleic Acids Res.
, vol.39
-
-
Forbes, S.A.1
-
36
-
-
79951834644
-
-
Wellcome Trust Sanger Institute
-
Wellcome Trust Sanger Institute. Catalogue of somatic mutations in cancer [online], www.sanger.ac.uk/perl/genetics/CGP/cosmic (2012).
-
(2012)
Catalogue of Somatic Mutations in Cancer
-
-
-
37
-
-
68149165614
-
Predicting the effects of coding non-synonymous variants on protein function using the SIFT algorithm
-
Kumar, P., Henikoff, S. & Ng, P.C. Predicting the effects of coding non-synonymous variants on protein function using the SIFT algorithm. Nat. Protoc. 4, 1073-1081 (2009).
-
(2009)
Nat. Protoc.
, vol.4
, pp. 1073-1081
-
-
Kumar, P.1
Henikoff, S.2
Ng, P.C.3
-
38
-
-
79953715693
-
Improving the assessment of the outcome of nonsynonymous SNVs with a consensus deleteriousness score, Condel
-
Gonzalez-Perez, A. & Lopez-Bigas, N. Improving the assessment of the outcome of nonsynonymous SNVs with a consensus deleteriousness score, Condel. Am.J. Hum. Genet. 88, 440-449 (2011).
-
(2011)
Am.J. Hum. Genet.
, vol.88
, pp. 440-449
-
-
Gonzalez-Perez, A.1
Lopez-Bigas, N.2
-
39
-
-
84856890066
-
Resistance patterns with tyrosine kinase inhibitors in melanoma: New insights
-
Dummer, R. & Flaherty, K.T. Resistance patterns with tyrosine kinase inhibitors in melanoma: new insights. Curr. Opin. Oncol. 24, 150-154 (2012).
-
(2012)
Curr. Opin. Oncol.
, vol.24
, pp. 150-154
-
-
Dummer, R.1
Flaherty, K.T.2
-
40
-
-
77951139631
-
Genome remodelling in a basal-like breast cancer metastasis and xenograft
-
Ding, L. et al. Genome remodelling in a basal-like breast cancer metastasis and xenograft. Nature 464, 999-1005 (2010).
-
(2010)
Nature
, vol.464
, pp. 999-1005
-
-
Ding, L.1
-
41
-
-
2942652786
-
In vitro mutation artifacts after formalin fixation and error prone translesion synthesis during PCR
-
Quach, N., Goodman, M.F. & Shibata, D. In vitro mutation artifacts after formalin fixation and error prone translesion synthesis during PCR. BMC Clin. Pathol. 4, 1 (2004).
-
(2004)
BMC Clin. Pathol.
, vol.4
, pp. 1
-
-
Quach, N.1
Goodman, M.F.2
Shibata, D.3
-
42
-
-
3242696821
-
Mutational profiling in the human genome
-
Wilson, R.K. et al. Mutational profiling in the human genome. Cold Spring Harb. Symp. Quant. Biol. 68, 23-29 (2003). (Pubitemid 38955548)
-
(2003)
Cold Spring Harbor Symposia on Quantitative Biology
, vol.68
, pp. 23-29
-
-
Wilson, R.K.1
Ley, T.J.2
Cole, F.S.3
Milbrandt, J.D.4
Clifton, S.5
Fulton, L.6
Fewell, G.7
Minx, P.8
Sun, H.9
McLellan, M.10
Pohl, C.11
Mardis, E.R.12
-
43
-
-
4444344330
-
EGF receptor gene mutations are common in lung cancers from "never smokers" and are associated with sensitivity of tumors to gefitinib and erlotinib
-
DOI 10.1073/pnas.0405220101
-
Pao, W. et al. EGF receptor gene mutations are common in lung cancers from "never smokers" and are associated with sensitivity of tumors to gefitinib and erlotinib. Proc. Natl Acad. Sci. USA 101, 13306-13311 (2004). (Pubitemid 39209661)
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, Issue.36
, pp. 13306-13311
-
-
Pao, W.1
Miller, V.2
Zakowski, M.3
Doherty, J.4
Politi, K.5
Sarkaria, I.6
Singh, B.7
Heelan, R.8
Rusch, V.9
Fulton, L.10
Mardis, E.11
Kupfer, D.12
Wilson, R.13
Kris, M.14
Varmus, H.15
-
44
-
-
2342624080
-
EGFR mutations in lung, cancer: Correlation with clinical response to gefitinib therapy
-
DOI 10.1126/science.1099314
-
Paez, J.G. et al. EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy. Science 304, 1497-1500 (2004). (Pubitemid 38720929)
-
(2004)
Science
, vol.304
, Issue.5676
, pp. 1497-1500
-
-
Paez, J.G.1
Janne, P.A.2
Lee, J.C.3
Tracy, S.4
Greulich, H.5
Gabriel, S.6
Herman, P.7
Kaye, F.J.8
Lindeman, N.9
Boggon, T.J.10
Naoki, K.11
Sasaki, H.12
Fujii, Y.13
Eck, M.J.14
Sellers, W.R.15
Johnson, B.E.16
Meyerson, M.17
-
45
-
-
52149123619
-
Core signaling pathways in human pancreatic cancers revealed by global genomic analyses
-
Jones, S. et al. Core signaling pathways in human pancreatic cancers revealed by global genomic analyses. Science 321, 1801-1806 (2008).
-
(2008)
Science
, vol.321
, pp. 1801-1806
-
-
Jones, S.1
-
46
-
-
78049398107
-
Distant metastasis occurs late during the genetic evolution of pancreatic cancer
-
Yachida, S. et al. Distant metastasis occurs late during the genetic evolution of pancreatic cancer. Nature 467, 1114-1117 (2010).
-
(2010)
Nature
, vol.467
, pp. 1114-1117
-
-
Yachida, S.1
-
47
-
-
78049380554
-
The patterns and dynamics of genomic instability in metastatic pancreatic cancer
-
Campbell, P.J. et al. The patterns and dynamics of genomic instability in metastatic pancreatic cancer. Nature 467, 1109-1113 (2010).
-
(2010)
Nature
, vol.467
, pp. 1109-1113
-
-
Campbell, P.J.1
-
48
-
-
84856082746
-
Computational modeling of pancreatic cancer reveals kinetics of metastasis suggesting optimum treatment strategies
-
Haeno, H. et al. Computational modeling of pancreatic cancer reveals kinetics of metastasis suggesting optimum treatment strategies. Cell 148, 362-375 (2012).
-
(2012)
Cell
, vol.148
, pp. 362-375
-
-
Haeno, H.1
-
49
-
-
77952090720
-
Adjuvant chemoradiation for pancreatic adenocarcinoma: The Johns Hopkins Hospital-Mayo Clinic collaborative study
-
Hsu, C.C. et al. Adjuvant chemoradiation for pancreatic adenocarcinoma: the Johns Hopkins Hospital-Mayo Clinic collaborative study. Ann. Surg. Oncol. 17, 981-990 (2010).
-
(2010)
Ann. Surg. Oncol.
, vol.17
, pp. 981-990
-
-
Hsu, C.C.1
-
50
-
-
79955512732
-
Neoadjuvant therapy is associated with improved survival in resectable pancreatic adenocarcinoma
-
Artinyan, A., Anaya, D.A., McKenzie, S., Ellenhorn, J.D. & Kim, J. Neoadjuvant therapy is associated with improved survival in resectable pancreatic adenocarcinoma. Cancer 117, 2044-2049 (2011).
-
(2011)
Cancer
, vol.117
, pp. 2044-2049
-
-
Artinyan, A.1
Anaya, D.A.2
McKenzie, S.3
Ellenhorn, J.D.4
Kim, J.5
-
51
-
-
84859947197
-
Sleeping Beauty mutagenesis reveals cooperating mutations and pathways in pancreatic adenocarcinoma
-
Mann, K.M. et al. Sleeping Beauty mutagenesis reveals cooperating mutations and pathways in pancreatic adenocarcinoma. Proc. Natl Acad. Sci. USA 109, 5934-5941 (2012).
-
(2012)
Proc. Natl Acad. Sci. USA
, vol.109
, pp. 5934-5941
-
-
Mann, K.M.1
-
52
-
-
67149143399
-
Inhibition of Hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer
-
Olive, K.P. et al. Inhibition of Hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer. Science 324, 1457-1461 (2009).
-
(2009)
Science
, vol.324
, pp. 1457-1461
-
-
Olive, K.P.1
-
53
-
-
78149298209
-
Suppression of antitumor immunity by stromal cells expressing fibroblast activation protein-alpha
-
Kraman, M. et al. Suppression of antitumor immunity by stromal cells expressing fibroblast activation protein-alpha. Science 330, 827-830 (2010).
-
(2010)
Science
, vol.330
, pp. 827-830
-
-
Kraman, M.1
|