메뉴 건너뛰기




Volumn 96, Issue 8, 2012, Pages 1117-1121

Anti-inflammatory effect of quercetin in a whole orbital tissue culture of graves' orbitopathy

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; LACTATE DEHYDROGENASE; MESSENGER RNA; QUERCETIN; TUMOR NECROSIS FACTOR ALPHA;

EID: 84864833156     PISSN: 00071161     EISSN: 14682079     Source Type: Journal    
DOI: 10.1136/bjophthalmol-2012-301537     Document Type: Article
Times cited : (56)

References (32)
  • 1
    • 33745661418 scopus 로고    scopus 로고
    • Pathogenesis of Graves ophthalmopathy: Implications for prediction, prevention, and treatment
    • Garrity JA, Bahn RS. Pathogenesis of Graves ophthalmopathy: implications for prediction, prevention, and treatment. Am J Ophthalmol 2006;142:147-53.
    • (2006) Am J Ophthalmol , vol.142 , pp. 147-153
    • Garrity, J.A.1    Bahn, R.S.2
  • 3
    • 77349104615 scopus 로고    scopus 로고
    • Graves' ophthalmopathy
    • Bahn RS. Graves' ophthalmopathy. N Engl J Med 2010;362:726-38.
    • (2010) N Engl J Med , vol.362 , pp. 726-738
    • Bahn, R.S.1
  • 4
    • 51849117368 scopus 로고    scopus 로고
    • Immune mechanisms in thyroid eye disease
    • Lehmann GM, Feldon SE, Smith TJ, et al. Immune mechanisms in thyroid eye disease. Thyroid 2008;18:959-65.
    • (2008) Thyroid , vol.18 , pp. 959-965
    • Lehmann, G.M.1    Feldon, S.E.2    Smith, T.J.3
  • 5
    • 0034454231 scopus 로고    scopus 로고
    • Management of graves' ophthalmopathy: Reality and perspectives
    • DOI 10.1210/er.21.2.168
    • Bartalena L, Pinchera A, Marcocci C. Management of Graves' ophthalmopathy: reality and perspectives. Endocr Rev 2000;21:168-99. (Pubitemid 32275594)
    • (2000) Endocrine Reviews , vol.21 , Issue.2 , pp. 168-199
    • Bartalena, L.1    Pinchera, A.2    Marcocci, C.3
  • 6
    • 80054776633 scopus 로고    scopus 로고
    • Quercetin inhibits IL-1beta-induced inflammation, hyaluronan production and adipogenesis in orbital fibroblasts from Graves' orbitopathy
    • Yoon JS, Lee HJ, Choi SH, et al. Quercetin inhibits IL-1beta-induced inflammation, hyaluronan production and adipogenesis in orbital fibroblasts from Graves' orbitopathy. PLoS One 2011;6:e26261.
    • (2011) PLoS One , vol.6
    • Yoon, J.S.1    Lee, H.J.2    Choi, S.H.3
  • 7
    • 14744294057 scopus 로고    scopus 로고
    • In vivo quercitrin anti-inflammatory effect involves release of quercetin, which inhibits inflammation through down-regulation of the NF-κB pathway
    • DOI 10.1002/eji.200425778
    • Comalada M, Camuesco D, Sierra S, et al. In vivo quercitrin anti-inflammatory effect involves release of quercetin, which inhibits inflammation through down-regulation of the NF-kappaB pathway. Eur J Immunol 2005;35:584-92. (Pubitemid 40331335)
    • (2005) European Journal of Immunology , vol.35 , Issue.2 , pp. 584-592
    • Comalada, M.1    Camuesco, D.2    Sierra, S.3    Ballester, I.4    Xaus, J.5    Galvez, J.6    Zarzuelo, A.7
  • 8
    • 68149138453 scopus 로고    scopus 로고
    • Quercetin inhibits IL-1 beta-induced ICAM-1 expression in pulmonary epithelial cell line A549 through the MAPK pathways
    • Ying B, Yang T, Song X, et al. Quercetin inhibits IL-1 beta-induced ICAM-1 expression in pulmonary epithelial cell line A549 through the MAPK pathways. Mol Biol Rep 2009;36:1825-32.
    • (2009) Mol Biol Rep , vol.36 , pp. 1825-1832
    • Ying, B.1    Yang, T.2    Song, X.3
  • 9
    • 60349097870 scopus 로고    scopus 로고
    • Inhibition of reactive oxygen species and pre-neoplastic lesions by quercetin through an antioxidant defense mechanism
    • Vasquez-Garzon VR, Arellanes-Robledo J, Garcia-Roman R, et al. Inhibition of reactive oxygen species and pre-neoplastic lesions by quercetin through an antioxidant defense mechanism. Free Radic Res 2009;43:128-37.
    • (2009) Free Radic Res , vol.43 , pp. 128-137
    • Vasquez-Garzon, V.R.1    Arellanes-Robledo, J.2    Garcia-Roman, R.3
  • 10
    • 69049106394 scopus 로고    scopus 로고
    • Structural basis of the anti-inflammatory activity of quercetin: Inhibition of the 5-hydroxytryptamine type 2 receptor
    • Rotelli AE, Aguilar CF, Pelzer LE. Structural basis of the anti-inflammatory activity of quercetin: inhibition of the 5-hydroxytryptamine type 2 receptor. Eur Biophys J 2009;38:865-71.
    • (2009) Eur Biophys J , vol.38 , pp. 865-871
    • Rotelli, A.E.1    Aguilar, C.F.2    Pelzer, L.E.3
  • 11
    • 77649336979 scopus 로고    scopus 로고
    • Anti-inflammatory effect of quercetin-loaded microemulsion in the airways allergic inflammatory model in mice
    • Rogerio AP, Dora CL, Andrade EL, et al. Anti-inflammatory effect of quercetin-loaded microemulsion in the airways allergic inflammatory model in mice. Pharmacol Res 2010;61:288-97.
    • (2010) Pharmacol Res , vol.61 , pp. 288-297
    • Rogerio, A.P.1    Dora, C.L.2    Andrade, E.L.3
  • 12
    • 79955024423 scopus 로고    scopus 로고
    • Whole orbital tissue culture identifies imatinib mesylate and adalimumab as potential therapeutics for Graves' ophthalmopathy
    • van Steensel L, van Hagen PM, Paridaens D, et al. Whole orbital tissue culture identifies imatinib mesylate and adalimumab as potential therapeutics for Graves' ophthalmopathy. Br J Ophthalmol 2011;95:735-8.
    • (2011) Br J Ophthalmol , vol.95 , pp. 735-738
    • Van Steensel, L.1    Van Hagen, P.M.2    Paridaens, D.3
  • 13
    • 12344317859 scopus 로고    scopus 로고
    • Reevaluating thyrotropin receptor-induced mouse models of graves' disease and ophthalmopathy
    • DOI 10.1210/en.2004-1015
    • Baker G, Mazziotti G, von Ruhland C, et al. Reevaluating thyrotropin receptor-induced mouse models of Graves' disease and ophthalmopathy. Endocrinology 2005;146:835-44. (Pubitemid 40129841)
    • (2005) Endocrinology , vol.146 , Issue.2 , pp. 835-844
    • Baker, G.1    Mazziotti, G.2    Von Ruhland, C.3    Ludgate, M.4
  • 14
    • 0030872679 scopus 로고    scopus 로고
    • Clinical activity score as a guide in the management of patients with Graves' ophthalmopathy
    • Mourits MP, Prummel MF, Wiersinga WM, et al. Clinical activity score as a guide in the management of patients with Graves' ophthalmopathy. Clin Endocrinol (Oxf) 1997;47:9-14. (Pubitemid 27313981)
    • (1997) Clinical Endocrinology , vol.47 , Issue.1 , pp. 9-14
    • Mourits, M.Ph.1    Prummel, M.F.2    Wiersinga, W.M.3    Koornneef, L.4
  • 15
    • 0035710746 scopus 로고    scopus 로고
    • -ΔΔCT method
    • DOI 10.1006/meth.2001.1262
    • Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-delta delta C(T)) method. Methods 2001;25:402-8. (Pubitemid 34164012)
    • (2001) Methods , vol.25 , Issue.4 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 16
    • 0141787948 scopus 로고    scopus 로고
    • Relative overexpression of macrophage-derived cytokines in orbital adipose tissue from patients with Graves' ophthalmopathy
    • DOI 10.1210/jc.2003-030380
    • Kumar S, Bahn RS. Relative overexpression of macrophage-derived cytokines in orbital adipose tissue from patients with Graves' ophthalmopathy. J Clin Endocrinol Metab 2003;88:4246-50. (Pubitemid 37153727)
    • (2003) Journal of Clinical Endocrinology and Metabolism , vol.88 , Issue.9 , pp. 4246-4250
    • Kumar, S.1    Bahn, R.S.2
  • 17
    • 0036202054 scopus 로고    scopus 로고
    • Orbital fibroblasts exhibit a novel pattern of responses to proinflammatory cytokines: Potential basis for the pathogenesis of thyroid-associated ophthalmopathy
    • Smith TJ. Orbital fibroblasts exhibit a novel pattern of responses to proinflammatory cytokines: potential basis for the pathogenesis of thyroid-associated ophthalmopathy. Thyroid 2002;12:197-203. (Pubitemid 34259799)
    • (2002) Thyroid , vol.12 , Issue.3 , pp. 197-203
    • Smith, T.J.1
  • 18
    • 0037080029 scopus 로고    scopus 로고
    • Igs from patients with Graves' disease induce the expression of T cell chemoattractants in their fibroblasts
    • Pritchard J, Horst N, Cruikshank W, et al. Igs from patients with Graves' disease induce the expression of T cell chemoattractants in their fibroblasts. J Immunol 2002;168:942-50. (Pubitemid 34049599)
    • (2002) Journal of Immunology , vol.168 , Issue.2 , pp. 942-950
    • Pritchard, J.1    Horst, N.2    Cruikshank, W.3    Smith, T.J.4
  • 19
    • 0026663136 scopus 로고
    • Graves' immunoglobulins and cytokines stimulate the expression of intercellular adhesion molecule-1 (ICAM-1) in cultured Graves' orbital fibroblasts
    • Heufelder AE, Bahn RS. Graves' immunoglobulins and cytokines stimulate the expression of intercellular adhesion molecule-1 (ICAM-1) in cultured Graves' orbital fibroblasts. Eur J Clin Invest 1992;22:529-37.
    • (1992) Eur J Clin Invest , vol.22 , pp. 529-537
    • Heufelder, A.E.1    Bahn, R.S.2
  • 21
    • 65549134290 scopus 로고    scopus 로고
    • Orbital fibroblasts from patients with thyroid-associated ophthalmopathy overexpress CD40: CD154 hyperinduces IL-6, IL-8, and MCP-1
    • Hwang CJ, Afifiyan N, Sand D, et al. Orbital fibroblasts from patients with thyroid-associated ophthalmopathy overexpress CD40: CD154 hyperinduces IL-6, IL-8, and MCP-1. Invest Ophthalmol Vis Sci 2009;50:2262-8.
    • (2009) Invest Ophthalmol Vis Sci , vol.50 , pp. 2262-2268
    • Hwang, C.J.1    Afifiyan, N.2    Sand, D.3
  • 22
    • 23244464983 scopus 로고    scopus 로고
    • IL-1β induces IL-6 expression in human orbital fibroblasts: Identification of an anatomic-site specific phenotypic attribute relevant to thyroid-associated ophthalmopathy
    • Chen B, Tsui S, Smith TJ. IL-1 beta induces IL-6 expression in human orbital fibroblasts: identification of an anatomic-site specific phenotypic attribute relevant to thyroid-associated ophthalmopathy. J Immunol 2005;175:1310-19. (Pubitemid 41095021)
    • (2005) Journal of Immunology , vol.175 , Issue.2 , pp. 1310-1319
    • Chen, B.1    Tsui, S.2    Smith, T.J.3
  • 23
    • 0031966785 scopus 로고    scopus 로고
    • Orbital fibroblast chemokine modulation: Effects of dexamethasone and cyclosporin A
    • Burnstine MA, Elner SG, Elner VM. Orbital fibroblast chemokine modulation: effects of dexamethasone and cyclosporin A. Br J Ophthalmol 1998;82:318-22. (Pubitemid 28177125)
    • (1998) British Journal of Ophthalmology , vol.82 , Issue.3 , pp. 318-322
    • Burnstine, M.A.1    Elner, S.G.2    Elner, V.M.3
  • 24
    • 78650837135 scopus 로고    scopus 로고
    • PGE2 induces IL-6 in orbital fibroblasts through EP2 receptors and increased gene promoter activity: Implications to thyroid-associated ophthalmopathy
    • Raychaudhuri N, Douglas RS, Smith TJ. PGE2 induces IL-6 in orbital fibroblasts through EP2 receptors and increased gene promoter activity: implications to thyroid-associated ophthalmopathy. PLoS One 2010;5:e15296.
    • (2010) PLoS One , vol.5
    • Raychaudhuri, N.1    Douglas, R.S.2    Smith, T.J.3
  • 25
    • 79955650634 scopus 로고    scopus 로고
    • The pro- and anti-inflammatory properties of the cytokine interleukin-6
    • Scheller J, Chalaris A, Schmidt-Arras D, et al. The pro- and anti-inflammatory properties of the cytokine interleukin-6. Biochim Biophysica Acta 2011;1813:878-88.
    • (2011) Biochim Biophysica Acta , vol.1813 , pp. 878-888
    • Scheller, J.1    Chalaris, A.2    Schmidt-Arras, D.3
  • 26
    • 77956326466 scopus 로고    scopus 로고
    • Averting inflammation by targeting the cytokine environment
    • Kopf M, Bachmann MF, Marsland BJ. Averting inflammation by targeting the cytokine environment. Nat Rev Drug Discov 2010;9:703-18.
    • (2010) Nat Rev Drug Discov , vol.9 , pp. 703-718
    • Kopf, M.1    Bachmann, M.F.2    Marsland, B.J.3
  • 27
    • 0037337051 scopus 로고    scopus 로고
    • TSH-R expression and cytokine profile in orbital tissue of active vs. inactive Graves' ophthalmopathy patients
    • DOI 10.1046/j.1365-2265.2003.01708.x
    • Wakelkamp IM, Bakker O, Baldeschi L, et al. TSH-R expression and cytokine profile in orbital tissue of active vs. inactive Graves' ophthalmopathy patients. Clin Endocrinol (Oxf) 2003;58:280-7. (Pubitemid 36308115)
    • (2003) Clinical Endocrinology , vol.58 , Issue.3 , pp. 280-287
    • Wakelkamp, I.M.M.J.1    Bakker, O.2    Baldeschi, L.3    Wiersinga, W.M.4    Prummel, M.F.5
  • 28
    • 55149104161 scopus 로고    scopus 로고
    • Quercetin: Potentials in the prevention and therapy of disease
    • Bischoff SC. Quercetin: potentials in the prevention and therapy of disease. Curr Opin Clin Nutr Metab Care 2008;11:733-40.
    • (2008) Curr Opin Clin Nutr Metab Care , vol.11 , pp. 733-740
    • Bischoff, S.C.1
  • 29
    • 0032562766 scopus 로고    scopus 로고
    • Quercetin is recovered in human plasma as conjugated derivatives which retain antioxidant properties
    • DOI 10.1016/S0014-5793(98)00367-6, PII S0014579398003676
    • Manach C, Morand C, Crespy V, et al. Quercetin is recovered in human plasma as conjugated derivatives which retain antioxidant properties. FEBS Lett 1998;426:331-6. (Pubitemid 28218374)
    • (1998) FEBS Letters , vol.426 , Issue.3 , pp. 331-336
    • Manach, C.1    Morand, C.2    Crespy, V.3    Demigne, C.4    Texier, O.5    Regerat, F.6    Remesy, C.7
  • 30
    • 0035370769 scopus 로고    scopus 로고
    • Identification of quercetin 3-O-β-D-glucuronide as an antioxidative metabolite in rat plasma after oral administration of quercetin
    • DOI 10.1016/S0891-5849(01)00522-6, PII S0891584901005226
    • Moon JH, Tsushida T, Nakahara K, et al. Identification of quercetin 3-O-beta-D-glucuronide as an antioxidative metabolite in rat plasma after oral administration of quercetin. Free Radic Biol Med 2001;30:1274-85. (Pubitemid 32463938)
    • (2001) Free Radical Biology and Medicine , vol.30 , Issue.11 , pp. 1274-1285
    • Moon, J.-H.1    Tsushida, T.2    Nakahara, K.3    Terao, J.4
  • 31
    • 79955020771 scopus 로고    scopus 로고
    • Pharmacology in health food: Metabolism of quercetin in vivo and its protective effect against arteriosclerosis
    • Ishizawa K, Yoshizumi M, Kawai Y, et al. Pharmacology in health food: metabolism of quercetin in vivo and its protective effect against arteriosclerosis. J Pharmacol Sci 2011;115:466-70.
    • (2011) J Pharmacol Sci , vol.115 , pp. 466-470
    • Ishizawa, K.1    Yoshizumi, M.2    Kawai, Y.3
  • 32
    • 34548812546 scopus 로고    scopus 로고
    • A critical review of the data related to the safety of quercetin and lack of evidence of in vivo toxicity, including lack of genotoxic/carcinogenic properties
    • DOI 10.1016/j.fct.2007.05.015, PII S0278691507001780
    • Harwood M, Danielewska-Nikiel B, Borzelleca JF, et al. A critical review of the data related to the safety of quercetin and lack of evidence of in vivo toxicity, including lack of genotoxic/carcinogenic properties. Food Chem Toxicol 2007;45:2179-205. (Pubitemid 47451573)
    • (2007) Food and Chemical Toxicology , vol.45 , Issue.11 , pp. 2179-2205
    • Harwood, M.1    Danielewska-Nikiel, B.2    Borzelleca, J.F.3    Flamm, G.W.4    Williams, G.M.5    Lines, T.C.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.