Orbital fibroblasts from patients with thyroidassociated ophthalmopathy overexpress cd40: CD154 hyperinduces IL-6, IL-8, and MCP-1

Investigative Ophthalmology and Visual Science

Volumn 50, Issue 5, 2009, Pages 2262-2268

  Hwang, Catherine J ^a,b   Afifiyan, Nikoo ^c   Sand, Daniel ^c   Naik, Vibha ^c   Said, Jonathan ^b   Pollock, Stephen J ^d   Chen, Beiling ^c   Phipps, Richard P ^d   Goldberg, Robert A ^a,b   Smith, Terry J ^a,b,c   Douglas, Raymond S ^a,b,c,e  

^a JULES STEIN EYE INSTITUTE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c HARBOR UCLA MEDICAL CENTER   (United States)

^d UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY   (United States)

^e Greater Los Angeles Veterans Hospital   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD40 ANTIGEN; CD40 LIGAND; CYTOKINE RECEPTOR; DEXAMETHASONE; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; JANUS KINASE 2; MONOCYTE CHEMOTACTIC PROTEIN 1; N BENZYL 2 CYANO 3 (3,4 DIHYDROXYPHENYL)ACRYLAMIDE; PROTEIN TYROSINE KINASE INHIBITOR; THY 1 ANTIGEN; ALPHA CYANO (3,4 DIHYDROXY) N BENZYLCINNAMIDE; ALPHA-CYANO-(3,4-DIHYDROXY)-N-BENZYLCINNAMIDE; CCL2 PROTEIN, HUMAN; ENZYME INHIBITOR; GAMMA INTERFERON; IL6 PROTEIN, HUMAN; JAK2 PROTEIN, HUMAN; TYRPHOSTIN;

ARTICLE; CELL CULTURE; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENDOCRINE OPHTHALMOPATHY; FIBROBLAST; FLOW CYTOMETRY; HUMAN; HUMAN CELL; HUMAN TISSUE; MICROSCOPY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; UPREGULATION; BIOSYNTHESIS; DRUG EFFECT; ENZYME IMMUNOASSAY; METABOLISM; ORBIT; PATHOLOGY;

ANTIGENS, CD40; ANTIGENS, THY-1; CD40 LIGAND; CELLS, CULTURED; CHEMOKINE CCL2; DEXAMETHASONE; ENZYME INHIBITORS; FIBROBLASTS; FLOW CYTOMETRY; GRAVES OPHTHALMOPATHY; HUMANS; IMMUNOENZYME TECHNIQUES; INTERFERON-GAMMA; INTERLEUKIN-1BETA; INTERLEUKIN-6; INTERLEUKIN-8; JANUS KINASE 2; ORBIT; TYRPHOSTINS; UP-REGULATION;

EID: 65549134290     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.08-2328     Document Type: Article

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