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Volumn 6, Issue 10, 2011, Pages

Quercetin inhibits IL-1β-induced inflammation, hyaluronan production and adipogenesis in orbital fibroblasts from graves' orbitopathy

Author keywords

[No Author keywords available]

Indexed keywords

CCAAT ENHANCER BINDING PROTEIN ALPHA; CCAAT ENHANCER BINDING PROTEIN BETA; CYCLOOXYGENASE 2; FAT DROPLET; HYALURONIC ACID; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; MESSENGER RNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; Q 0125; QUERCETIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; TRANSCRIPTION FACTOR;

EID: 80054776633     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0026261     Document Type: Article
Times cited : (71)

References (35)
  • 1
    • 33745661418 scopus 로고    scopus 로고
    • Pathogenesis of graves ophthalmopathy: implications for prediction, prevention, and treatment
    • Garrity JA, Bahn RS, (2006) Pathogenesis of graves ophthalmopathy: implications for prediction, prevention, and treatment. Am J Ophthalmol 142: 147-153.
    • (2006) Am J Ophthalmol , vol.142 , pp. 147-153
    • Garrity, J.A.1    Bahn, R.S.2
  • 4
    • 0029815152 scopus 로고    scopus 로고
    • Evidence of adipocyte differentiation in human orbital fibroblasts in primary culture
    • Sorisky A, Pardasani D, Gagnon A, Smith TJ, (1996) Evidence of adipocyte differentiation in human orbital fibroblasts in primary culture. J Clin Endocrinol Metab 81: 3428-3431.
    • (1996) J Clin Endocrinol Metab , vol.81 , pp. 3428-3431
    • Sorisky, A.1    Pardasani, D.2    Gagnon, A.3    Smith, T.J.4
  • 6
    • 0034454231 scopus 로고    scopus 로고
    • Management of Graves' ophthalmopathy: reality and perspectives
    • Bartalena L, Pinchera A, Marcocci C, (2000) Management of Graves' ophthalmopathy: reality and perspectives. Endocr Rev 21: 168-199.
    • (2000) Endocr Rev , vol.21 , pp. 168-199
    • Bartalena, L.1    Pinchera, A.2    Marcocci, C.3
  • 7
    • 4644226020 scopus 로고    scopus 로고
    • Quercetin-induced growth inhibition and cell death in nasopharyngeal carcinoma cells are associated with increase in Bad and hypophosphorylated retinoblastoma expressions
    • Ong CS, Tran E, Nguyen TT, Ong CK, Lee SK, et al. (2004) Quercetin-induced growth inhibition and cell death in nasopharyngeal carcinoma cells are associated with increase in Bad and hypophosphorylated retinoblastoma expressions. Oncol Rep 11: 727-733.
    • (2004) Oncol Rep , vol.11 , pp. 727-733
    • Ong, C.S.1    Tran, E.2    Nguyen, T.T.3    Ong, C.K.4    Lee, S.K.5
  • 8
    • 0041709308 scopus 로고    scopus 로고
    • Low concentrations of quercetin and ellagic acid synergistically influence proliferation, cytotoxicity and apoptosis in MOLT-4 human leukemia cells
    • Mertens-Talcott SU, Talcott ST, Percival SS, (2003) Low concentrations of quercetin and ellagic acid synergistically influence proliferation, cytotoxicity and apoptosis in MOLT-4 human leukemia cells. J Nutr 133: 2669-2674.
    • (2003) J Nutr , vol.133 , pp. 2669-2674
    • Mertens-Talcott, S.U.1    Talcott, S.T.2    Percival, S.S.3
  • 9
    • 0031969571 scopus 로고    scopus 로고
    • Effect of antioxidants, resveratrol, quercetin, and N-acetylcysteine, on the functions of cultured rat hepatic stellate cells and Kupffer cells
    • Kawada N, Seki S, Inoue M, Kuroki T, (1998) Effect of antioxidants, resveratrol, quercetin, and N-acetylcysteine, on the functions of cultured rat hepatic stellate cells and Kupffer cells. Hepatology 27: 1265-1274.
    • (1998) Hepatology , vol.27 , pp. 1265-1274
    • Kawada, N.1    Seki, S.2    Inoue, M.3    Kuroki, T.4
  • 10
    • 14744294057 scopus 로고    scopus 로고
    • In vivo quercitrin anti-inflammatory effect involves release of quercetin, which inhibits inflammation through down-regulation of the NF-kappaB pathway
    • Comalada M, Camuesco D, Sierra S, Ballester I, Xaus J, et al. (2005) In vivo quercitrin anti-inflammatory effect involves release of quercetin, which inhibits inflammation through down-regulation of the NF-kappaB pathway. Eur J Immunol 35: 584-592.
    • (2005) Eur J Immunol , vol.35 , pp. 584-592
    • Comalada, M.1    Camuesco, D.2    Sierra, S.3    Ballester, I.4    Xaus, J.5
  • 11
    • 68149138453 scopus 로고    scopus 로고
    • Quercetin inhibits IL-1 beta-induced ICAM-1 expression in pulmonary epithelial cell line A549 through the MAPK pathways
    • Ying B, Yang T, Song X, Hu X, Fan H, et al. (2009) Quercetin inhibits IL-1 beta-induced ICAM-1 expression in pulmonary epithelial cell line A549 through the MAPK pathways. Mol Biol Rep 36: 1825-1832.
    • (2009) Mol Biol Rep , vol.36 , pp. 1825-1832
    • Ying, B.1    Yang, T.2    Song, X.3    Hu, X.4    Fan, H.5
  • 12
    • 57349156235 scopus 로고    scopus 로고
    • Combined effects of genistein, quercetin, and resveratrol in human and 3T3-L1 adipocytes
    • Park HJ, Yang JY, Ambati S, Della-Fera MA, Hausman DB, et al. (2008) Combined effects of genistein, quercetin, and resveratrol in human and 3T3-L1 adipocytes. J Med Food 11: 773-783.
    • (2008) J Med Food , vol.11 , pp. 773-783
    • Park, H.J.1    Yang, J.Y.2    Ambati, S.3    Della-Fera, M.A.4    Hausman, D.B.5
  • 13
    • 48949115243 scopus 로고    scopus 로고
    • The anti-obesity effect of quercetin is mediated by the AMPK and MAPK signaling pathways
    • Ahn J, Lee H, Kim S, Park J, Ha T, (2008) The anti-obesity effect of quercetin is mediated by the AMPK and MAPK signaling pathways. Biochem Biophys Res Commun 373: 545-549.
    • (2008) Biochem Biophys Res Commun , vol.373 , pp. 545-549
    • Ahn, J.1    Lee, H.2    Kim, S.3    Park, J.4    Ha, T.5
  • 14
    • 0347722803 scopus 로고    scopus 로고
    • Inhibition of rat fat cell lipolysis by monoamine oxidase and semicarbazide-sensitive amine oxidase substrates
    • Visentin V, Prevot D, Marti L, Carpene C, (2003) Inhibition of rat fat cell lipolysis by monoamine oxidase and semicarbazide-sensitive amine oxidase substrates. Eur J Pharmacol 466: 235-243.
    • (2003) Eur J Pharmacol , vol.466 , pp. 235-243
    • Visentin, V.1    Prevot, D.2    Marti, L.3    Carpene, C.4
  • 15
    • 80054093205 scopus 로고    scopus 로고
    • Quercetin Decreases Proliferation of Orbital Fibroblasts and Their Release of Hyaluronic Acid
    • Lisi S, Botta R, Lemmi M, Sellari-Franceschini S, Altea MA, et al. (2011) Quercetin Decreases Proliferation of Orbital Fibroblasts and Their Release of Hyaluronic Acid. J Endocrinol Invest 34: 521-527.
    • (2011) J Endocrinol Invest , vol.34 , pp. 521-527
    • Lisi, S.1    Botta, R.2    Lemmi, M.3    Sellari-Franceschini, S.4    Altea, M.A.5
  • 16
    • 33846107566 scopus 로고    scopus 로고
    • Smoking and thyroid-associated ophthalmopathy: A novel explanation of the biological link
    • Cawood TJ, Moriarty P, O'Farrelly C, O'Shea D, (2007) Smoking and thyroid-associated ophthalmopathy: A novel explanation of the biological link. J Clin Endocrinol Metab 92: 59-64.
    • (2007) J Clin Endocrinol Metab , vol.92 , pp. 59-64
    • Cawood, T.J.1    Moriarty, P.2    O'Farrelly, C.3    O'Shea, D.4
  • 17
    • 0037080029 scopus 로고    scopus 로고
    • Igs from patients with Graves' disease induce the expression of T cell chemoattractants in their fibroblasts
    • Pritchard J, Horst N, Cruikshank W, Smith TJ, (2002) Igs from patients with Graves' disease induce the expression of T cell chemoattractants in their fibroblasts. Journal of immunology 168: 942-950.
    • (2002) Journal of Immunology , vol.168 , pp. 942-950
    • Pritchard, J.1    Horst, N.2    Cruikshank, W.3    Smith, T.J.4
  • 18
    • 77957335301 scopus 로고    scopus 로고
    • The expression of intercellular adhesion molecule-1 induced by CD40-CD40L ligand signaling in orbital fibroblasts in patients with Graves' ophthalmopathy
    • Zhao LQ, Wei RL, Cheng JW, Cai JP, Li Y, (2010) The expression of intercellular adhesion molecule-1 induced by CD40-CD40L ligand signaling in orbital fibroblasts in patients with Graves' ophthalmopathy. Invest Ophthalmol Vis Sci 51: 4652-4660.
    • (2010) Invest Ophthalmol Vis Sci , vol.51 , pp. 4652-4660
    • Zhao, L.Q.1    Wei, R.L.2    Cheng, J.W.3    Cai, J.P.4    Li, Y.5
  • 19
    • 0026663136 scopus 로고
    • Graves' immunoglobulins and cytokines stimulate the expression of intercellular adhesion molecule-1 (ICAM-1) in cultured Graves' orbital fibroblasts
    • Heufelder AE, Bahn RS, (1992) Graves' immunoglobulins and cytokines stimulate the expression of intercellular adhesion molecule-1 (ICAM-1) in cultured Graves' orbital fibroblasts. Eur J Clin Invest 22: 529-537.
    • (1992) Eur J Clin Invest , vol.22 , pp. 529-537
    • Heufelder, A.E.1    Bahn, R.S.2
  • 20
    • 0034453080 scopus 로고    scopus 로고
    • Cytokine profiles in eye muscle tissue and orbital fat tissue from patients with thyroid-associated ophthalmopathy
    • Hiromatsu Y, Yang D, Bednarczuk T, Miyake I, Nonaka K, et al. (2000) Cytokine profiles in eye muscle tissue and orbital fat tissue from patients with thyroid-associated ophthalmopathy. J Clin Endocrinol Metab 85: 1194-1199.
    • (2000) J Clin Endocrinol Metab , vol.85 , pp. 1194-1199
    • Hiromatsu, Y.1    Yang, D.2    Bednarczuk, T.3    Miyake, I.4    Nonaka, K.5
  • 21
    • 65549134290 scopus 로고    scopus 로고
    • Orbital fibroblasts from patients with thyroid-associated ophthalmopathy overexpress CD40: CD154 hyperinduces IL-6, IL-8, and MCP-1
    • Hwang CJ, Afifiyan N, Sand D, Naik V, Said J, et al. (2009) Orbital fibroblasts from patients with thyroid-associated ophthalmopathy overexpress CD40: CD154 hyperinduces IL-6, IL-8, and MCP-1. Invest Ophthalmol Vis Sci 50: 2262-2268.
    • (2009) Invest Ophthalmol Vis Sci , vol.50 , pp. 2262-2268
    • Hwang, C.J.1    Afifiyan, N.2    Sand, D.3    Naik, V.4    Said, J.5
  • 22
    • 23244464983 scopus 로고    scopus 로고
    • IL-1 beta induces IL-6 expression in human orbital fibroblasts: identification of an anatomic-site specific phenotypic attribute relevant to thyroid-associated ophthalmopathy
    • Chen B, Tsui S, Smith TJ, (2005) IL-1 beta induces IL-6 expression in human orbital fibroblasts: identification of an anatomic-site specific phenotypic attribute relevant to thyroid-associated ophthalmopathy. J Immunol 175: 1310-1319.
    • (2005) J Immunol , vol.175 , pp. 1310-1319
    • Chen, B.1    Tsui, S.2    Smith, T.J.3
  • 23
    • 0031966785 scopus 로고    scopus 로고
    • Orbital fibroblast chemokine modulation: effects of dexamethasone and cyclosporin A
    • Burnstine MA, Elner SG, Elner VM, (1998) Orbital fibroblast chemokine modulation: effects of dexamethasone and cyclosporin A. Br J Ophthalmol 82: 318-322.
    • (1998) Br J Ophthalmol , vol.82 , pp. 318-322
    • Burnstine, M.A.1    Elner, S.G.2    Elner, V.M.3
  • 24
    • 0037337051 scopus 로고    scopus 로고
    • TSH-R expression and cytokine profile in orbital tissue of active vs. inactive Graves' ophthalmopathy patients
    • Wakelkamp IM, Bakker O, Baldeschi L, Wiersinga WM, Prummel MF, (2003) TSH-R expression and cytokine profile in orbital tissue of active vs. inactive Graves' ophthalmopathy patients. Clin Endocrinol (Oxf) 58: 280-287.
    • (2003) Clin Endocrinol (Oxf) , vol.58 , pp. 280-287
    • Wakelkamp, I.M.1    Bakker, O.2    Baldeschi, L.3    Wiersinga, W.M.4    Prummel, M.F.5
  • 25
    • 0032491496 scopus 로고    scopus 로고
    • Activation of human orbital fibroblasts through CD40 engagement results in a dramatic induction of hyaluronan synthesis and prostaglandin endoperoxide H synthase-2 expression. Insights into potential pathogenic mechanisms of thyroid-associated ophthalmopathy
    • Cao HJ, Wang HS, Zhang Y, Lin HY, Phipps RP, et al. (1998) Activation of human orbital fibroblasts through CD40 engagement results in a dramatic induction of hyaluronan synthesis and prostaglandin endoperoxide H synthase-2 expression. Insights into potential pathogenic mechanisms of thyroid-associated ophthalmopathy. J Biol Chem 273: 29615-29625.
    • (1998) J Biol Chem , vol.273 , pp. 29615-29625
    • Cao, H.J.1    Wang, H.S.2    Zhang, Y.3    Lin, H.Y.4    Phipps, R.P.5
  • 26
    • 34447516158 scopus 로고    scopus 로고
    • Activated human T lymphocytes express cyclooxygenase-2 and produce proadipogenic prostaglandins that drive human orbital fibroblast differentiation to adipocytes
    • Feldon SE, O'Loughlin CW, Ray DM, Landskroner-Eiger S, Seweryniak KE, et al. (2006) Activated human T lymphocytes express cyclooxygenase-2 and produce proadipogenic prostaglandins that drive human orbital fibroblast differentiation to adipocytes. Am J Pathol 169: 1183-1193.
    • (2006) Am J Pathol , vol.169 , pp. 1183-1193
    • Feldon, S.E.1    O'Loughlin, C.W.2    Ray, D.M.3    Landskroner-Eiger, S.4    Seweryniak, K.E.5
  • 27
    • 0027365837 scopus 로고
    • Pathogenesis of Graves' ophthalmopathy
    • Bahn RS, Heufelder AE, (1993) Pathogenesis of Graves' ophthalmopathy. N Engl J Med 329: 1468-1475.
    • (1993) N Engl J Med , vol.329 , pp. 1468-1475
    • Bahn, R.S.1    Heufelder, A.E.2
  • 28
    • 0033345351 scopus 로고    scopus 로고
    • Expression of hyaluronan synthase messenger ribonucleic acids and their induction by interleukin-1beta in human orbital fibroblasts: potential insight into the molecular pathogenesis of thyroid-associated ophthalmopathy
    • Kaback LA, Smith TJ, (1999) Expression of hyaluronan synthase messenger ribonucleic acids and their induction by interleukin-1beta in human orbital fibroblasts: potential insight into the molecular pathogenesis of thyroid-associated ophthalmopathy. J Clin Endocrinol Metab 84: 4079-4084.
    • (1999) J Clin Endocrinol Metab , vol.84 , pp. 4079-4084
    • Kaback, L.A.1    Smith, T.J.2
  • 29
    • 0028929143 scopus 로고
    • Leukoregulin is a potent inducer of hyaluronan synthesis in cultured human orbital fibroblasts
    • Smith TJ, Wang HS, Evans CH, (1995) Leukoregulin is a potent inducer of hyaluronan synthesis in cultured human orbital fibroblasts. Am J Physiol 268: C382-388.
    • (1995) Am J Physiol , vol.268
    • Smith, T.J.1    Wang, H.S.2    Evans, C.H.3
  • 30
    • 55449097618 scopus 로고    scopus 로고
    • Resveratrol induces apoptosis and inhibits adipogenesis in 3T3-L1 adipocytes
    • Rayalam S, Yang JY, Ambati S, Della-Fera MA, Baile CA, (2008) Resveratrol induces apoptosis and inhibits adipogenesis in 3T3-L1 adipocytes. Phytother Res 22: 1367-1371.
    • (2008) Phytother Res , vol.22 , pp. 1367-1371
    • Rayalam, S.1    Yang, J.Y.2    Ambati, S.3    Della-Fera, M.A.4    Baile, C.A.5
  • 31
    • 53849149299 scopus 로고    scopus 로고
    • Structure and physiological functions of the human peroxisome proliferator-activated receptor gamma
    • Zieleniak A, Wojcik M, Wozniak LA, (2008) Structure and physiological functions of the human peroxisome proliferator-activated receptor gamma. Arch Immunol Ther Exp (Warsz) 56: 331-345.
    • (2008) Arch Immunol Ther Exp (Warsz) , vol.56 , pp. 331-345
    • Zieleniak, A.1    Wojcik, M.2    Wozniak, L.A.3
  • 32
    • 0028256153 scopus 로고
    • Potentiation of beta-adrenoceptor agonist-mediated lipolysis by quercetin and fisetin in isolated rat adipocytes
    • Kuppusamy UR, Das NP, (1994) Potentiation of beta-adrenoceptor agonist-mediated lipolysis by quercetin and fisetin in isolated rat adipocytes. Biochem Pharmacol 47: 521-529.
    • (1994) Biochem Pharmacol , vol.47 , pp. 521-529
    • Kuppusamy, U.R.1    Das, N.P.2
  • 33
    • 33749075554 scopus 로고    scopus 로고
    • The effects of tumour necrosis factor-alpha and interleukin1 on an in vitro model of thyroid-associated ophthalmopathy; contrasting effects on adipogenesis
    • Cawood TJ, Moriarty P, O'Farrelly C, O'Shea D, (2006) The effects of tumour necrosis factor-alpha and interleukin1 on an in vitro model of thyroid-associated ophthalmopathy; contrasting effects on adipogenesis. Eur J Endocrinol 155: 395-403.
    • (2006) Eur J Endocrinol , vol.155 , pp. 395-403
    • Cawood, T.J.1    Moriarty, P.2    O'Farrelly, C.3    O'Shea, D.4
  • 34
    • 55149104161 scopus 로고    scopus 로고
    • Quercetin: potentials in the prevention and therapy of disease
    • Bischoff SC, (2008) Quercetin: potentials in the prevention and therapy of disease. Curr Opin Clin Nutr Metab Care 11: 733-740.
    • (2008) Curr Opin Clin Nutr Metab Care , vol.11 , pp. 733-740
    • Bischoff, S.C.1
  • 35
    • 0016693548 scopus 로고
    • An established preadipose cell line and its differentiation in culture. II. Factors affecting the adipose conversion
    • Green H, Kehinde O, (1975) An established preadipose cell line and its differentiation in culture. II. Factors affecting the adipose conversion. Cell 5: 19-27.
    • (1975) Cell , vol.5 , pp. 19-27
    • Green, H.1    Kehinde, O.2


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