Orbital fibroblast chemokine modulation: Effects of dexamethasone and cyclosporin A

British Journal of Ophthalmology

Volumn 82, Issue 3, 1998, Pages 318-322

  Burnstine, Michael A ^a,c   Elner, Susan G ^a   Elner, Victor M ^a,b  

^a UNIVERSITY OF MICHIGAN   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE; CORTICOSTEROID; CYCLOSPORIN A; DEXAMETHASONE; IMMUNOMODULATING AGENT; INTERLEUKIN 8; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; RECOMBINANT INTERLEUKIN 1BETA;

ARTICLE; CELL INFILTRATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FIBROBLAST; FIBROBLAST CULTURE; HUMAN; HUMAN CELL; LEUKOCYTE; MESSENGER RNA SYNTHESIS; NORTHERN BLOTTING; ORBIT; ORBIT DISEASE; PRIORITY JOURNAL; PROTEIN SECRETION;

EID: 0031966785     PISSN: 00071161     EISSN: None     Source Type: Journal    
DOI: 10.1136/bjo.82.3.318     Document Type: Article

References (34)

1. Rootman J. Diseases of the orbit. Philadelphia: JB Lippincott, 1988:141-280.
2. Kennerdell JS, Dresner SC. The nonspecific orbital inflammatory syndromes. Surv Ophthalmol 1984;29:93-103.
3. White V, Rootman J, Quenville N, et al. Orbital lymphoproliferative and inflammatory lesions. Can J Ophthalmol 1987;22:362-73.
4. Weetman AP. Thyroid-associated eye disease: pathophysiology. Lancet 1991;338:25-32.
5. Elner VM, Burnstine MA, Kunkel SL, et al. Interleukin-8 and monocyte chemotactic protein-1 gene expression and protein produection by human orbital fibroblasts. Ophthalmic Plastic Reconstruct Surg (in press).
6. Oppenheim JJ, Zachariae COC, Mukaida N, et al. Properties of the novel proinflammatory supergene "intercrine" cytokine family. Annu Rev Immunol 1991;9:617-48.
7. Strieter RM, Koch AE, Antony VB, et al. The immunopathology of chemotactic cytokines: the role of interleukin-8 and monocyte chemoattractant protein-1. J Lab Clin Med 1994;123:183-97.
8. Baggiolini M, Dewald B, Moser B. Interleukin-8 and related chemotactic cytokines - CXC and CC chemokines. Adv Immunol 1994;55:97-179.
9. Standford TJ, Kunkel SL, Basha MA, et al. Interleukin-8 gene expression by a pulmonary epithelial cell line: a model for cytokine networks in the lung. J Clin Invest 1990;86: 1945-53.
10. Antony VB, Hott JW, Kunkel SL, et al. Pleural mesothelial cell expression of C-C (monocyte chemotactic peptide) and C-X-C (interleukin 8) chemokines. Am J Respir Cell Mol Biol 1995;12:581-8.
11. Chirgwin JM, Przybyla AE, MacDonald RJ, et al. Isolation of biologically active RNA from sources enriched in ribonuclease. Biochemistry 1979;18:5294-9.
12. Jonas E, Sargent TD, Dawid IB. Epidermal keratin gene expressed in embryos of Xenopus laevis. Proc Natl Acad Sci 1985;82:5413-7.
13. Elner VM, Strieter RM, Elner SG, et al. Neutrophil chemotactic factor (IL-8) gene expression by cytokine-treated retinal pigment epithelial cells. Am J Pathol 1990;136:745-50.
14. Elner SG, Strieter RM, Elner VM, et al. Monocyte chemotactic protein gene expression by cytokine-treated human retinal pigment epithelial cells. Lab Invest 1991;64:819-25.
15. Klett ZG, Elner SG, Elner VM. Differential expression of immunoreactive HLA-DR and ICAM-1 in human cultured orbital fibroblasts and orbital tissue. Ophthalmic Plastic Reconstruct Surg 1996;12:153-62.
16. Heufelder AE, Bahn RS. Elevated expression in situ of selectin and immunoglobulin superfamily type adhesion molecules in retroocular connective tissues from patients with Graves' ophthalmopathy. Clin Exp Immunol 1993;91: 381-9.
17. Heufelder AE, Bahn RS. Graves' immunoglobulins and cytokines stimulate the expression of intercellular adhesion molecule-1 (ICAM-1) in cultured Graves' orbital fibroblasts. Eur J Clin Invest 1992;22:529-37.
18. Bahn RS, Heufelder AE. Retroocular fibroblasts: important effector cells in Graves' ophthalmopathy. Thyroid 1992;2: 89-94.
19. Heufelder AE, Smith TJ, Gorman, Bahn RS. Increased induction of HLA-DR by interferon-γ in cultured fibroblasts derived from patients with Graves' ophthalmopathy and pretibial dermopathy. J Clin Endocrinol Metab 1991;73: 307-13.
20. Heufelder AE, Bahn RS. Detection and localization of cytokine immunoreactivity in retro-ocular connective tissue in Graves' ophthalmopathy. Eur J Clin Invest 1993;23:10-7.
21. Heufelder AE, Bahn RS. Modulation of Graves' orbital fibroblast proliferation by cytokines and glucocorticoid receptor agonists. Invest Ophthalmol Vis Sci 1994;35:120-7.
22. Korducki JM, Loftus SJ, Bahn RS. Stimulation of glycosaminoglycan production in cultured human retroocular fibroblasts. Invest Ophthalmol Vis Sci 1992;33:2037-42.
23. Smith TJ, Bahn RS, Gorman CA, Cheavens M. Stimulation of glycosaminoglycan accumulation by interferon gamma in cultured human retroocular fibroblasts. J Clin Endocrinol Metab 1991;72:1169-71.
24. Bahn RS, Garrity JA, Gorman CA. Diagnosis and management of Graves' ophthalmopathy. J Clin Endocrinol Metab 1990;71:559-63.
25. Ferrick MR, Thurau SR, Oppenheim MH, et al. Ocular inflammation stimulated by intravitreal interleukin-8 and MCP-1. Invest Ophthalmol Vis Sci 1991;32:1534-9.
26. Elner SG, Elner VM, Jaffe GJ, et al. Cytokines in proliferative diabetic retinopathy and proliferative vitreoretinopathy. Curr Eye Res 1995;14:1045-3.
27. Abu El-Asrar AM, Van Damme J, Put W, et al. Monocyte chemotactic protein-1 in proliferative vitreoretinal disorders. Am J Ophthalmol 1997;123:599-606.
28. Rosenbaum JT, Planck SR, Huang XN, et al. Detection of mRNA for the cytokines, interleukin-1α, and interleukin-8, in corneas from patients with pseudophakic bullous keratopathy. Invest Ophthalmol Vis Sci 1995;36:2151-5.
29. Wingett D, Forcier K, Nielson CP. Glucocorticoid-mediated inhibition of RANTES expression in human T lymphocytes. FEBS Lett 1996;398:308-11.
30. Berkman N, Robichaud A, Krishnan VL, et al. Expression of RANTES in human airway epithelial cells: effect of corticosteroids and interleukin-4, -10, and -13. Immunology 1996;87:599-603.
31. Imam AP, Halpern GM. Uses, adverse effects of abuse of corticosteroids. Part I. Allergol Immunopathol 1994;22:250-60.
32. Nelson PA, Kawamura A, Akselband Y, et al. Effect of immunosuppressive drugs on cytokine gene transcription studied by message amplificaton phenotyping (mapping) polymerase chain reaction. Transplant Proc 1991;23:2867-9.
33. Wiederrecht G, Lam E, Hung S, et al. The mechansim of action of FK-506 and cyclosporin A. Ann NY Acad Sci 1993;696:9-19.
34. Physicians desk reference. 49th ed. 1995.