-
1
-
-
0030725173
-
The thyrotropin receptor in thyroid disease
-
Paschke R, Ludgate M 1997 The thyrotropin receptor in thyroid disease. N Engl J Med 337:1675-1681
-
(1997)
N Engl J Med
, vol.337
, pp. 1675-1681
-
-
Paschke, R.1
Ludgate, M.2
-
2
-
-
0036129562
-
Unlocking the immunological mechanisms of orbital inflammation in thyroid eye disease
-
Ludgate M, Baker GR 2002 Unlocking the immunological mechanisms of orbital inflammation in thyroid eye disease. Clin Exp Immunol 127:193-198
-
(2002)
Clin Exp Immunol
, vol.127
, pp. 193-198
-
-
Ludgate, M.1
Baker, G.R.2
-
3
-
-
0346057834
-
Current perspective on the pathogenesis of Graves' disease and ophthalmopathy
-
Prabhakar BS, Bahn RS, Smith TJ 2003 Current perspective on the pathogenesis of Graves' disease and ophthalmopathy. Endocr Rev 24:802-835
-
(2003)
Endocr Rev
, vol.24
, pp. 802-835
-
-
Prabhakar, B.S.1
Bahn, R.S.2
Smith, T.J.3
-
4
-
-
0033158423
-
Differentiation of human orbital preadipocyte fibroblasts induces expression of functional thyrotropin receptor
-
Valyasevi R, Erickson D, Harteneck D, Dutton C, Heufelder A, Jyonouchi S, Bahn R 1999 Differentiation of human orbital preadipocyte fibroblasts induces expression of functional thyrotropin receptor. J Clin Endocrinol Metab 84:2557-2562
-
(1999)
J Clin Endocrinol Metab
, vol.84
, pp. 2557-2562
-
-
Valyasevi, R.1
Erickson, D.2
Harteneck, D.3
Dutton, C.4
Heufelder, A.5
Jyonouchi, S.6
Bahn, R.7
-
5
-
-
0033770835
-
Adipogenesis in thyroid eye disease
-
Crisp MS, Starkey KJ, Lane C, Ham J, Ludgate M 2000 Adipogenesis in thyroid eye disease. Invest Ophthalmol Vis Sci 41:3249-3255
-
(2000)
Invest Ophthalmol Vis Sci
, vol.41
, pp. 3249-3255
-
-
Crisp, M.S.1
Starkey, K.J.2
Lane, C.3
Ham, J.4
Ludgate, M.5
-
6
-
-
0037241030
-
PPARγ in thyroid eye disease: Contra-indication for thiazolidenedione use?
-
Starkey K, Heufelder A, Baker G, Joba W, Evans M, Davies S, Ludgate M 2003 PPARγ in thyroid eye disease: contra-indication for thiazolidenedione use? J Clin Endocrinol Metab 88:55-59
-
(2003)
J Clin Endocrinol Metab
, vol.88
, pp. 55-59
-
-
Starkey, K.1
Heufelder, A.2
Baker, G.3
Joba, W.4
Evans, M.5
Davies, S.6
Ludgate, M.7
-
7
-
-
0038683276
-
Adipose thyrotropin receptor expression is elevated in Graves' and thyroid eye diseases ex vivo and indicates adipogenesis in progress in vivo
-
Starkey KJ, Janezic A, Jones G, Jordan N, Baker G, Ludgate M 2003 Adipose thyrotropin receptor expression is elevated in Graves' and thyroid eye diseases ex vivo and indicates adipogenesis in progress in vivo. J Mol Endocrinol 30: 369-380
-
(2003)
J Mol Endocrinol
, vol.30
, pp. 369-380
-
-
Starkey, K.J.1
Janezic, A.2
Jones, G.3
Jordan, N.4
Baker, G.5
Ludgate, M.6
-
8
-
-
0141481280
-
Animal models of Graves' hyperthyroidism
-
Seetharamaiah GS 2003 Animal models of Graves' hyperthyroidism. Autoimmunity 36:381-387
-
(2003)
Autoimmunity
, vol.36
, pp. 381-387
-
-
Seetharamaiah, G.S.1
-
9
-
-
0033951221
-
Animal models of Graves' disease
-
Ludgate M 2000 Animal models of Graves' disease. Eur J Endocrinol 142:1-8
-
(2000)
Eur J Endocrinol
, vol.142
, pp. 1-8
-
-
Ludgate, M.1
-
10
-
-
0034992477
-
Iodine and thyroid autoimmune disease in animal models
-
Ruwhof C, Drexhage HA 2001 Iodine and thyroid autoimmune disease in animal models. Thyroid 11:427-436
-
(2001)
Thyroid
, vol.11
, pp. 427-436
-
-
Ruwhof, C.1
Drexhage, H.A.2
-
11
-
-
0029835481
-
Transfer of thyroiditis, with syngeneic spleen-cells sensitized with the human thyrotropin receptor, to naive BALB/C and Nod mice
-
Costagliola S, Many MC, Stalmansfalys M, Vassart G, Ludgate M 1996 Transfer of thyroiditis, with syngeneic spleen-cells sensitized with the human thyrotropin receptor, to naive BALB/C and Nod mice. Endocrinology 137: 4637-4643
-
(1996)
Endocrinology
, vol.137
, pp. 4637-4643
-
-
Costagliola, S.1
Many, M.C.2
Stalmansfalys, M.3
Vassart, G.4
Ludgate, M.5
-
12
-
-
0033561544
-
Development of an animal model of autoimmune thyroid eye disease
-
Many MC, Costagliola S, Detrait M, Denef JF, Vassart G, Ludgate M 1999 Development of an animal model of autoimmune thyroid eye disease. J Immunol 162:4966-4974
-
(1999)
J Immunol
, vol.162
, pp. 4966-4974
-
-
Many, M.C.1
Costagliola, S.2
Detrait, M.3
Denef, J.F.4
Vassart, G.5
Ludgate, M.6
-
13
-
-
0036709804
-
Experimental model for ophthalmopathy in BALB/c and outbred (CD-1) mice genetically immunized with G2s and the thyrotropin receptor
-
Yamada M, Li AW, West KA, Chang CH, Wall JR 2002 Experimental model for ophthalmopathy in BALB/c and outbred (CD-1) mice genetically immunized with G2s and the thyrotropin receptor. Autoimmunity 35:403-413
-
(2002)
Autoimmunity
, vol.35
, pp. 403-413
-
-
Yamada, M.1
Li, A.W.2
West, K.A.3
Chang, C.H.4
Wall, J.R.5
-
14
-
-
0034027425
-
Genetic immunization of outbred mice with thyrotropin receptor cDNA provides a model of Graves' disease
-
Costagliola S, Many MC, Denef JF, Pohlenz J, Refetoff S, Vassart G 2000 Genetic immunization of outbred mice with thyrotropin receptor cDNA provides a model of Graves' disease. J Clin Invest 105:803-811
-
(2000)
J Clin Invest
, vol.105
, pp. 803-811
-
-
Costagliola, S.1
Many, M.C.2
Denef, J.F.3
Pohlenz, J.4
Refetoff, S.5
Vassart, G.6
-
15
-
-
0001291642
-
Development and course of exophthalmos and ophthalmoplegia in Graves' disease with special reference to the effect of thyroidectomy
-
Rundle FF, Wilson 1944 Development and course of exophthalmos and ophthalmoplegia in Graves' disease with special reference to the effect of thyroidectomy. Clin Sci 5:177-194
-
(1944)
Clin Sci
, vol.5
, pp. 177-194
-
-
Rundle, F.F.1
Wilson2
-
16
-
-
0028019518
-
Recombinant thyrotropin receptor and the induction of autoimmune thyroid-disease in Balb/C mice - A new animal-model
-
Costagliola S, Many MC, Stalmansfalys M, Tonacchera M, Vassart G, Ludgate M 1994 Recombinant thyrotropin receptor and the induction of autoimmune thyroid-disease in Balb/C mice-a new animal-model. Endocrinology 135:2150-2159
-
(1994)
Endocrinology
, vol.135
, pp. 2150-2159
-
-
Costagliola, S.1
Many, M.C.2
Stalmansfalys, M.3
Tonacchera, M.4
Vassart, G.5
Ludgate, M.6
-
17
-
-
0036284405
-
Demonstration of IgG, IgA and IgE autoantibodies to the human thyrotropin receptor using flow cytometry
-
Metcalfe R, Jordan N, Watson P, Gullu S, Wiltshire M, Crisp M, Evans C, Weetman A, Ludgate M 2002 Demonstration of IgG, IgA and IgE autoantibodies to the human thyrotropin receptor using flow cytometry. J Clin Endocrinol Metab 87:1754-1761
-
(2002)
J Clin Endocrinol Metab
, vol.87
, pp. 1754-1761
-
-
Metcalfe, R.1
Jordan, N.2
Watson, P.3
Gullu, S.4
Wiltshire, M.5
Crisp, M.6
Evans, C.7
Weetman, A.8
Ludgate, M.9
-
18
-
-
0017690690
-
Proof without prejudice: Use of the Kolmogarov-Smirnov test for the analysis of histograms from flow systems and other sources
-
Young IT 1977 Proof without prejudice: use of the Kolmogarov-Smirnov test for the analysis of histograms from flow systems and other sources. J Histochem Cytochem 25:935-941
-
(1977)
J Histochem Cytochem
, vol.25
, pp. 935-941
-
-
Young, I.T.1
-
19
-
-
0035076043
-
A luminescent bioassay for thyroid blocking antibodies
-
Jordan N, Rinderle C, Ashfield J, Morgenthaler N, Lazarus J, Ludgate M, Evans C 2001 A luminescent bioassay for thyroid blocking antibodies. Clin Endocrinol (Oxf) 54:355-364
-
(2001)
Clin Endocrinol (Oxf)
, vol.54
, pp. 355-364
-
-
Jordan, N.1
Rinderle, C.2
Ashfield, J.3
Morgenthaler, N.4
Lazarus, J.5
Ludgate, M.6
Evans, C.7
-
20
-
-
0026661174
-
T-cell responses to synthetic TSH receptor peptides in Graves disease
-
Tandon N, Freeman MA, Weetman AP 1992 T-cell responses to synthetic TSH receptor peptides in Graves disease. Clin Exp Immunol 89:468-473
-
(1992)
Clin Exp Immunol
, vol.89
, pp. 468-473
-
-
Tandon, N.1
Freeman, M.A.2
Weetman, A.P.3
-
21
-
-
0034913835
-
Naked TSH receptor DNA vaccination: A TH1 T cell response in which interferon-γ production, rather than antibody, dominates the immune response in mice
-
Pichurin P, Yan XM, Farilla L, Guo J, Chazenbalk GD, Rapoport B, McLachlan SM 2001 Naked TSH receptor DNA vaccination: a TH1 T cell response in which interferon-γ production, rather than antibody, dominates the immune response in mice. Endocrinology 142:3530-3536
-
(2001)
Endocrinology
, vol.142
, pp. 3530-3536
-
-
Pichurin, P.1
Yan, X.M.2
Farilla, L.3
Guo, J.4
Chazenbalk, G.D.5
Rapoport, B.6
McLachlan, S.M.7
-
22
-
-
0037227647
-
Contrasting activities of thyrotropin receptor antibodies in experimental models of Graves' disease induced by injection of transfected fibroblasts or deoxyribonucleic acid vaccination
-
Rao PV, Watson PF, Weetman AP, Carayanniotis G, Banga JP 2003 Contrasting activities of thyrotropin receptor antibodies in experimental models of Graves' disease induced by injection of transfected fibroblasts or deoxyribonucleic acid vaccination. Endocrinology 144:260-266
-
(2003)
Endocrinology
, vol.144
, pp. 260-266
-
-
Rao, P.V.1
Watson, P.F.2
Weetman, A.P.3
Carayanniotis, G.4
Banga, J.P.5
-
23
-
-
0037087373
-
A novel murine model of Graves' hyperthyroidism with intramuscular injection of adenovirus expressing the thyrotropin receptor
-
Nagayama Y, Kita-Furuyama M, Ando T, Nakao K, Mizuguchi H, Hayakawa T, Eguchi K, Niwa M 2002 A novel murine model of Graves' hyperthyroidism with intramuscular injection of adenovirus expressing the thyrotropin receptor. J Immunol 168:2789-2794
-
(2002)
J Immunol
, vol.168
, pp. 2789-2794
-
-
Nagayama, Y.1
Kita-Furuyama, M.2
Ando, T.3
Nakao, K.4
Mizuguchi, H.5
Hayakawa, T.6
Eguchi, K.7
Niwa, M.8
-
24
-
-
0018838337
-
Development of thymus, parathyroids, and ultimo-branchial bodies in NMRI and nude mice
-
Cordier A, Haumont S 1980 Development of thymus, parathyroids, and ultimo-branchial bodies in NMRI and nude mice. Am J Anat 157:227-263
-
(1980)
Am J Anat
, vol.157
, pp. 227-263
-
-
Cordier, A.1
Haumont, S.2
-
25
-
-
0031939694
-
Genetic immunization against the human thyrotropin receptor causes thyroiditis and allows production of monoclonal antibodies recognising the native receptor
-
Costagliola S, Rodien P, Many MC, Ludgate M, Vassart G 1998 Genetic immunization against the human thyrotropin receptor causes thyroiditis and allows production of monoclonal antibodies recognising the native receptor. J Immunol 160:1458-1465
-
(1998)
J Immunol
, vol.160
, pp. 1458-1465
-
-
Costagliola, S.1
Rodien, P.2
Many, M.C.3
Ludgate, M.4
Vassart, G.5
-
26
-
-
0037867043
-
Studies on murine thyroiditis: New insights from organ flow cytometry
-
Caturegli P, Rose N, Kimura M, Kimura H, Tzou S 2003 Studies on murine thyroiditis: new insights from organ flow cytometry. Thyroid 13:419-426
-
(2003)
Thyroid
, vol.13
, pp. 419-426
-
-
Caturegli, P.1
Rose, N.2
Kimura, M.3
Kimura, H.4
Tzou, S.5
-
28
-
-
0015506817
-
Aberrant thymus tissue in rat and mouse thyroid
-
Vladutiu A, Rose N 1972 Aberrant thymus tissue in rat and mouse thyroid. Experientia 28:79-81
-
(1972)
Experientia
, vol.28
, pp. 79-81
-
-
Vladutiu, A.1
Rose, N.2
-
29
-
-
0018062438
-
Fixation artefacts in the external eye muscles in biopsy examinations. (A light microscopy and electron microscopy study)
-
Muhlendyck H, Syed A 1978 Fixation artefacts in the external eye muscles in biopsy examinations. (A light microscopy and electron microscopy study). Buch Augenarzt 73:181-191
-
(1978)
Buch Augenarzt
, vol.73
, pp. 181-191
-
-
Muhlendyck, H.1
Syed, A.2
-
30
-
-
0029746157
-
Induction of Graves-like disease in mice by immunization with fibroblasts transfected with the thyrotropin receptor and a class II molecule
-
Shimojo N, Kohno Y, Yamaguchi K-i, Kikuoka S-i, Hoshioka A, Niimi H, Hirai A, Tamura Y, Saito Y, Kohn LD, Tahara K 1996 Induction of Graves-like disease in mice by immunization with fibroblasts transfected with the thyrotropin receptor and a class II molecule. Proc Natl Acad Sci USA 93:11074-11079
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 11074-11079
-
-
Shimojo, N.1
Kohno, Y.2
Yamaguchi, K.-I.3
Kikuoka, S.-I.4
Hoshioka, A.5
Niimi, H.6
Hirai, A.7
Tamura, Y.8
Saito, Y.9
Kohn, L.D.10
Tahara, K.11
-
31
-
-
0032752706
-
Induction of experimental autoimmune Graves' disease in BALB/c mice
-
Kaithamana S, Fan J, Osuga Y, Liang SG, Prabhakar BS 1999 Induction of experimental autoimmune Graves' disease in BALB/c mice. J Immunol 163: 5157-5164
-
(1999)
J Immunol
, vol.163
, pp. 5157-5164
-
-
Kaithamana, S.1
Fan, J.2
Osuga, Y.3
Liang, S.G.4
Prabhakar, B.S.5
-
32
-
-
9144263120
-
A transgenic mouse with a deletion in the collagenous domain of adiponectin displays elevated circulating adiponectin and improved insulin sensitivity
-
Combs TP, Pajvani UB, Berg AH, Lin Y, Jelicks LA, Laplante M, Nawrocki AR, Rajala MW, Parlow AF, Cheeseboro L, Ding YY, Russell RG, Lindemann D, Hartley A, Baker GRC, Obici S, Deshaies Y, Ludgate M, Rossetti L, Scherer PE 2004 A transgenic mouse with a deletion in the collagenous domain of adiponectin displays elevated circulating adiponectin and improved insulin sensitivity. Endocrinology 145:367-383
-
(2004)
Endocrinology
, vol.145
, pp. 367-383
-
-
Combs, T.P.1
Pajvani, U.B.2
Berg, A.H.3
Lin, Y.4
Jelicks, L.A.5
Laplante, M.6
Nawrocki, A.R.7
Rajala, M.W.8
Parlow, A.F.9
Cheeseboro, L.10
Ding, Y.Y.11
Russell, R.G.12
Lindemann, D.13
Hartley, A.14
Baker, G.R.C.15
Obici, S.16
Deshaies, Y.17
Ludgate, M.18
Rossetti, L.19
Scherer, P.E.20
more..
-
33
-
-
0033396462
-
Improved radioimmunoassay for measurement of mouse thyrotropin in serum: Strain differences in thyrotropin concentration and thyrotroph sensitivity to thyroid hormone
-
Pohlenz J, Maqueem A, Cua K, Weiss R, Van Sande J, Refetoff S 1999 Improved radioimmunoassay for measurement of mouse thyrotropin in serum: strain differences in thyrotropin concentration and thyrotroph sensitivity to thyroid hormone. Thyroid 9:1256-1271
-
(1999)
Thyroid
, vol.9
, pp. 1256-1271
-
-
Pohlenz, J.1
Maqueem, A.2
Cua, K.3
Weiss, R.4
Van Sande, J.5
Refetoff, S.6
-
34
-
-
0028232544
-
A high iodine intake in Wistar rats results in the development of a thyroid-associated ectopic thymic tissue and is accompanied by a low thyroid autoimmune reactivity
-
Mooij P, de Wit H, Drexhage H 1994 A high iodine intake in Wistar rats results in the development of a thyroid-associated ectopic thymic tissue and is accompanied by a low thyroid autoimmune reactivity. Immunology 81:309-316
-
(1994)
Immunology
, vol.81
, pp. 309-316
-
-
Mooij, P.1
De Wit, H.2
Drexhage, H.3
|