메뉴 건너뛰기




Volumn , Issue , 2011, Pages 242-252

Multiple System Atrophy

Author keywords

synuclein; synucleinopathy; Glial cytoplasmic inclusion; Multiple system atrophy; Neuronal cytoplasmic inclusion; Neuropathology; Olivopontocerebellar atrophy; Review; Striatonigral degeneration

Indexed keywords


EID: 84864829369     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1002/9781444341256.ch24     Document Type: Chapter
Times cited : (8)

References (84)
  • 1
    • 52449086856 scopus 로고    scopus 로고
    • Second consensus statement on the diagnosis of multiple system atrophy
    • Gilman S, Wenning GK, Low PA et al. Second consensus statement on the diagnosis of multiple system atrophy. Neurology 2008; 71: 670-676.
    • (2008) Neurology , vol.71 , pp. 670-676
    • Gilman, S.1    Wenning, G.K.2    Low, P.A.3
  • 2
  • 3
    • 84923949767 scopus 로고
    • Dégénérescences nigro-striées et cérébello-nigro-striées
    • Adams RD, van Bogaert L, van der Eeken H. Dégénérescences nigro-striées et cérébello-nigro-striées. Psychiat Neurol 1961; 142: 219-259.
    • (1961) Psychiat Neurol , vol.142 , pp. 219-259
    • Adams, R.D.1    van Bogaert, L.2    van der Eeken, H.3
  • 4
    • 72849160194 scopus 로고
    • A neurologic syndrome associated with orthostatic hypotension
    • Shy GM, Drager GA. A neurologic syndrome associated with orthostatic hypotension. Arch Neurol 1960; 2: 511-527.
    • (1960) Arch Neurol , vol.2 , pp. 511-527
    • Shy, G.M.1    Drager, G.A.2
  • 5
    • 0014469501 scopus 로고
    • Orthostatic hypotension and nicotine sensitivity in a case of multiple system atrophy
    • Graham JG, Oppenheimer DR. Orthostatic hypotension and nicotine sensitivity in a case of multiple system atrophy. J Neurol Neurosurg Psychiatry 1969; 32: 28-34.
    • (1969) J Neurol Neurosurg Psychiatry , vol.32 , pp. 28-34
    • Graham, J.G.1    Oppenheimer, D.R.2
  • 6
    • 0033837087 scopus 로고    scopus 로고
    • Evolution of sporadic olivopontocerebellar atrophy into multiple system atrophy
    • Gilman S, Little R, Johanns J et al. Evolution of sporadic olivopontocerebellar atrophy into multiple system atrophy. Neurology 2000; 55: 527-532.
    • (2000) Neurology , vol.55 , pp. 527-532
    • Gilman, S.1    Little, R.2    Johanns, J.3
  • 8
    • 0024843373 scopus 로고
    • Glial cytoplasmic inclusions in the CNS of patients with multiple system atrophy (striatonigral degeneration, olivopontocerebellar atrophy and Shy-Drager syndrome)
    • Papp MI, Kahn JE, Lantos PL. Glial cytoplasmic inclusions in the CNS of patients with multiple system atrophy (striatonigral degeneration, olivopontocerebellar atrophy and Shy-Drager syndrome). J Neurol Sci 1989; 94: 79-100.
    • (1989) J Neurol Sci , vol.94 , pp. 79-100
    • Papp, M.I.1    Kahn, J.E.2    Lantos, P.L.3
  • 10
    • 0030695277 scopus 로고    scopus 로고
    • Incidence of progressive supranuclear palsy and multiple system atrophy in Olmsted County, Minnesota, 1976 to 1990
    • Bower JH, Maraganore DM, McDonnell SK, Rocca WA. Incidence of progressive supranuclear palsy and multiple system atrophy in Olmsted County, Minnesota, 1976 to 1990. Neurology 1997; 49: 1284-1288.
    • (1997) Neurology , vol.49 , pp. 1284-1288
    • Bower, J.H.1    Maraganore, D.M.2    McDonnell, S.K.3    Rocca, W.A.4
  • 11
    • 0033589692 scopus 로고    scopus 로고
    • Prevalence of progressive supranuclear palsy and multiple system atrophy: a cross-sectional study
    • Schrag A, Ben-Shlomo Y, Quinn NP. Prevalence of progressive supranuclear palsy and multiple system atrophy: a cross-sectional study. Lancet 1999; 354: 1771-1775.
    • (1999) Lancet , vol.354 , pp. 1771-1775
    • Schrag, A.1    Ben-Shlomo, Y.2    Quinn, N.P.3
  • 12
    • 34548182758 scopus 로고    scopus 로고
    • Features of probable multiple system atrophy patients identified among 4770 patients with parkinsonism enrolled in the multicentre registry of the German Competence Network on Parkinson's disease
    • Wüllner U, Schmitz-Hübsch T, Abele M, Antony G, Bauer P, Eggert K. Features of probable multiple system atrophy patients identified among 4770 patients with parkinsonism enrolled in the multicentre registry of the German Competence Network on Parkinson's disease. J Neural Transm 2007; 114: 1161-1165.
    • (2007) J Neural Transm , vol.114 , pp. 1161-1165
    • Wüllner, U.1    Schmitz-Hübsch, T.2    Abele, M.3    Antony, G.4    Bauer, P.5    Eggert, K.6
  • 13
    • 0031774904 scopus 로고    scopus 로고
    • The definition of multiple system atrophy: a review of recent developments
    • Lantos PL. The definition of multiple system atrophy: a review of recent developments. J Neuropathol Exp Neurol 1998; 57: 1099-1111.
    • (1998) J Neuropathol Exp Neurol , vol.57 , pp. 1099-1111
    • Lantos, P.L.1
  • 15
    • 34247168008 scopus 로고    scopus 로고
    • Multiplex families with multiple system atrophy
    • Hara K, Momose Y, Tokiguchi S et al. Multiplex families with multiple system atrophy. Arch Neurol 2007; 64: 545-551.
    • (2007) Arch Neurol , vol.64 , pp. 545-551
    • Hara, K.1    Momose, Y.2    Tokiguchi, S.3
  • 18
    • 0033618481 scopus 로고    scopus 로고
    • No mutation in the entire coding region of the alpha-synuclein gene in pathologically confirmed cases of multiple system atrophy
    • Ozawa T, Takano H, Onodera O et al. No mutation in the entire coding region of the alpha-synuclein gene in pathologically confirmed cases of multiple system atrophy. Neurosci Lett 1999; 270: 110-112.
    • (1999) Neurosci Lett , vol.270 , pp. 110-112
    • Ozawa, T.1    Takano, H.2    Onodera, O.3
  • 19
    • 0242300619 scopus 로고    scopus 로고
    • Alpha-Synuclein locus triplication causes Parkinson's disease
    • Singleton AB, Farrer M, Johnson J et al. Alpha-Synuclein locus triplication causes Parkinson's disease. Science 2003; 302: 841.
    • (2003) Science , vol.302 , pp. 841
    • Singleton, A.B.1    Farrer, M.2    Johnson, J.3
  • 20
    • 34547657291 scopus 로고    scopus 로고
    • Quantitative PCR-based screening of alpha-synuclein multiplication in multiple system atrophy
    • Lincoln SJ, Ross OA, Milkovic NM et al. Quantitative PCR-based screening of alpha-synuclein multiplication in multiple system atrophy. Parkinsonism Relat Disord 2007; 13: 340-342.
    • (2007) Parkinsonism Relat Disord , vol.13 , pp. 340-342
    • Lincoln, S.J.1    Ross, O.A.2    Milkovic, N.M.3
  • 21
    • 0034890258 scopus 로고    scopus 로고
    • Analysis of the expression level of alpha-synuclein mRNA using postmortem brain samples from pathologically confirmed cases of multiple system atrophy
    • Ozawa T, Okuizumi K, Ikeuchi T, Wakabayashi K, Takahashi H, Tsuji S. Analysis of the expression level of alpha-synuclein mRNA using postmortem brain samples from pathologically confirmed cases of multiple system atrophy. Acta Neuropathol (Berl) 2001; 102: 188-190.
    • (2001) Acta Neuropathol (Berl) , vol.102 , pp. 188-190
    • Ozawa, T.1    Okuizumi, K.2    Ikeuchi, T.3    Wakabayashi, K.4    Takahashi, H.5    Tsuji, S.6
  • 22
    • 67249139655 scopus 로고    scopus 로고
    • SNCA variants are associated with increased risk for multiple system atrophy
    • Scholz SW, Houlden H, Schulte C et al. SNCA variants are associated with increased risk for multiple system atrophy. Ann Neurol 2009; 65: 610-614.
    • (2009) Ann Neurol , vol.65 , pp. 610-614
    • Scholz, S.W.1    Houlden, H.2    Schulte, C.3
  • 23
    • 70349578343 scopus 로고    scopus 로고
    • Genetic variants of the alphasynuclein gene SNCA are associated with multiple system atrophy
    • Al-Chalabi A, Dürr A, Wood NW et al. Genetic variants of the alphasynuclein gene SNCA are associated with multiple system atrophy. PLoS One 2009; 4: 7114.
    • (2009) PLoS One , vol.4 , pp. 7114
    • Al-Chalabi, A.1    Dürr, A.2    Wood, N.W.3
  • 26
    • 47749123020 scopus 로고    scopus 로고
    • Disorders of movement and system degenerations
    • In: Ellison DW, Louis DN, Love S (eds) 8th edn. London: Arnold,
    • Ince PG, Clark B, Holton J, Revesz T, Wharton SB. Disorders of movement and system degenerations. In: Ellison DW, Louis DN, Love S (eds) Greenfield's Neuropathology, 8th edn. London: Arnold, 2007.
    • (2007) Greenfield's Neuropathology
    • Ince, P.G.1    Clark, B.2    Holton, J.3    Revesz, T.4    Wharton, S.B.5
  • 27
    • 34247276516 scopus 로고    scopus 로고
    • G2019S mutation in the leucine-rich repeat kinase 2 gene is not associated with multiple system atrophy
    • Ozelius LJ, Foroud T, May S et al. G2019S mutation in the leucine-rich repeat kinase 2 gene is not associated with multiple system atrophy. Mov Disord 2007; 22: 546-549.
    • (2007) Mov Disord , vol.22 , pp. 546-549
    • Ozelius, L.J.1    Foroud, T.2    May, S.3
  • 28
    • 64249149785 scopus 로고    scopus 로고
    • Familial parkinsonism: study of original Sagamihara PARK8 (I2020T) kindred with variable clinicopathologic outcomes
    • Hasegawa K, Stoessl AJ, Yokoyama T, Kowa H, Wszolek ZK, Yagishita S. Familial parkinsonism: study of original Sagamihara PARK8 (I2020T) kindred with variable clinicopathologic outcomes. Parkinsonism Relat Disord 2009; 15: 300-306.
    • (2009) Parkinsonism Relat Disord , vol.15 , pp. 300-306
    • Hasegawa, K.1    Stoessl, A.J.2    Yokoyama, T.3    Kowa, H.4    Wszolek, Z.K.5    Yagishita, S.6
  • 30
    • 73449102917 scopus 로고    scopus 로고
    • Recent developments in multiple system atrophy
    • Wenning GK, Stefanova N. Recent developments in multiple system atrophy. J Neurol 2009; 256: 1791-1808.
    • (2009) J Neurol , vol.256 , pp. 1791-1808
    • Wenning, G.K.1    Stefanova, N.2
  • 31
    • 0028323244 scopus 로고
    • Genitourinary dysfunction in multiple system atrophy: clinical features and treatment in 62 cases
    • Beck RO, Betts CD, Fowler CJ. Genitourinary dysfunction in multiple system atrophy: clinical features and treatment in 62 cases. J Urol 1994; 151: 1336-1341.
    • (1994) J Urol , vol.151 , pp. 1336-1341
    • Beck, R.O.1    Betts, C.D.2    Fowler, C.J.3
  • 33
    • 70549108189 scopus 로고    scopus 로고
    • Brain magnetic resonance imaging techniques in the diagnosis of parkinsonian syndromes
    • Seppi K, Poewe W. Brain magnetic resonance imaging techniques in the diagnosis of parkinsonian syndromes. Neuroimaging Clin N Am 2010; 20: 29-55.
    • (2010) Neuroimaging Clin N Am , vol.20 , pp. 29-55
    • Seppi, K.1    Poewe, W.2
  • 35
    • 0028659025 scopus 로고
    • Multiple system atrophy: natural history, MRI morphology, and dopamine receptor imaging with 123IBZM-SPECT
    • Schulz JB, Klockgether T, Petersen D et al. Multiple system atrophy: natural history, MRI morphology, and dopamine receptor imaging with 123IBZM-SPECT. J Neurol Neurosurg Psychiatry 1994; 57: 1047-1056.
    • (1994) J Neurol Neurosurg Psychiatry , vol.57 , pp. 1047-1056
    • Schulz, J.B.1    Klockgether, T.2    Petersen, D.3
  • 36
    • 67651146706 scopus 로고    scopus 로고
    • Proposed neuroimaging criteria for the diagnosis of multiple system atrophy
    • Brooks DJ, Seppi K. Proposed neuroimaging criteria for the diagnosis of multiple system atrophy. Mov Disord 2009; 24: 949-964.
    • (2009) Mov Disord , vol.24 , pp. 949-964
    • Brooks, D.J.1    Seppi, K.2
  • 37
    • 69949158515 scopus 로고    scopus 로고
    • MIBG scintigraphy for differentiating Parkinson's disease with autonomic dysfunction from Parkinsonism-predominant multiple system atrophy
    • Chung EJ, Lee WY, Yoon WT, Kim BJ, Lee GH. MIBG scintigraphy for differentiating Parkinson's disease with autonomic dysfunction from Parkinsonism-predominant multiple system atrophy. Mov Disord 2009; 24: 1650-1655.
    • (2009) Mov Disord , vol.24 , pp. 1650-1655
    • Chung, E.J.1    Lee, W.Y.2    Yoon, W.T.3    Kim, B.J.4    Lee, G.H.5
  • 38
    • 0031008754 scopus 로고    scopus 로고
    • Urodynamic and neurophysiological evaluation in Parkinson's disease and multiple system atrophy
    • Stocchi F, Carbone A, Inghilleri M et al. Urodynamic and neurophysiological evaluation in Parkinson's disease and multiple system atrophy. J Neurol Neurosurg Psychiatry 1997; 62: 507-511.
    • (1997) J Neurol Neurosurg Psychiatry , vol.62 , pp. 507-511
    • Stocchi, F.1    Carbone, A.2    Inghilleri, M.3
  • 41
    • 0032539785 scopus 로고    scopus 로고
    • Multiple system atrophy with severe involvement of the motor cortical areas and cerebral white matter
    • Wakabayashi K, Ikeuchi T, Ishikawa A, Takahashi H. Multiple system atrophy with severe involvement of the motor cortical areas and cerebral white matter. J Neurol Sci 1998; 156: 114-117.
    • (1998) J Neurol Sci , vol.156 , pp. 114-117
    • Wakabayashi, K.1    Ikeuchi, T.2    Ishikawa, A.3    Takahashi, H.4
  • 42
    • 34648813113 scopus 로고    scopus 로고
    • Multiple system atrophy: alpha-synuclein and neuronal degeneration
    • Yoshida M. Multiple system atrophy: alpha-synuclein and neuronal degeneration. Neuropathology 2007; 27: 484-493.
    • (2007) Neuropathology , vol.27 , pp. 484-493
    • Yoshida, M.1
  • 43
    • 35948994645 scopus 로고    scopus 로고
    • Proposed neuropathological criteria for the post mortem diagnosis of multiple system atrophy
    • Trojanowski JQ, Revesz T. Proposed neuropathological criteria for the post mortem diagnosis of multiple system atrophy. Neuropathol Appl Neurobiol 2007; 33: 615-620.
    • (2007) Neuropathol Appl Neurobiol , vol.33 , pp. 615-620
    • Trojanowski, J.Q.1    Revesz, T.2
  • 44
    • 10344260246 scopus 로고    scopus 로고
    • The spectrum of pathological involvement of the striatonigral and olivopontocerebellar systems in multiple system atrophy: clinicopathological correlations
    • Ozawa T, Paviour D, Quinn NP et al. The spectrum of pathological involvement of the striatonigral and olivopontocerebellar systems in multiple system atrophy: clinicopathological correlations. Brain 2004; 127: 2657-2671.
    • (2004) Brain , vol.127 , pp. 2657-2671
    • Ozawa, T.1    Paviour, D.2    Quinn, N.P.3
  • 45
    • 26444610170 scopus 로고    scopus 로고
    • Grading of neuropathology in multiple system atrophy: proposal for a novel scale
    • Jellinger KA, Seppi K, Wenning GK. Grading of neuropathology in multiple system atrophy: proposal for a novel scale. Mov Disord Suppl 2005; 12: S29-S36.
    • (2005) Mov Disord Suppl , vol.12
    • Jellinger, K.A.1    Seppi, K.2    Wenning, G.K.3
  • 46
    • 78649580574 scopus 로고    scopus 로고
    • The phenotype spectrum of Japanese multiple system atrophy
    • Ozawa T, Tada M, Kakita A et al. The phenotype spectrum of Japanese multiple system atrophy. J Neurol Neurosurg Psychiatry 2010; 81: 1253-1255.
    • (2010) J Neurol Neurosurg Psychiatry , vol.81 , pp. 1253-1255
    • Ozawa, T.1    Tada, M.2    Kakita, A.3
  • 47
    • 0028339722 scopus 로고
    • The distribution of oligodendroglial inclusions in multiple system atrophy and its relevance to clinical symptomatology
    • Papp MI, Lantos PL. The distribution of oligodendroglial inclusions in multiple system atrophy and its relevance to clinical symptomatology. Brain 1994; 117: 235-243.
    • (1994) Brain , vol.117 , pp. 235-243
    • Papp, M.I.1    Lantos, P.L.2
  • 48
    • 34547789387 scopus 로고    scopus 로고
    • Morphological substrate of autonomic failure and neurohormonal dysfunction in multiple system atrophy: impact on determining phenotype spectrum
    • Ozawa T. Morphological substrate of autonomic failure and neurohormonal dysfunction in multiple system atrophy: impact on determining phenotype spectrum. Acta Neuropathol (Berl) 2007; 114: 201-211.
    • (2007) Acta Neuropathol (Berl) , vol.114 , pp. 201-211
    • Ozawa, T.1
  • 49
    • 70349736190 scopus 로고    scopus 로고
    • Degeneration in different parkinsonian syndromes relates to astrocyte type and astrocyte protein expression
    • Song YJ, Halliday GM, Holton JL et al. Degeneration in different parkinsonian syndromes relates to astrocyte type and astrocyte protein expression. J Neuropathol Exp Neurol 2009; 68: 1073-1083.
    • (2009) J Neuropathol Exp Neurol , vol.68 , pp. 1073-1083
    • Song, Y.J.1    Halliday, G.M.2    Holton, J.L.3
  • 50
    • 43049102024 scopus 로고    scopus 로고
    • Glial cytoplasmic inclusions and tissue injury in multiple system atrophy: A quantitative study in white matter (olivopontocerebellar system) and gray matter (nigrostriatal system)
    • Ishizawa K, Komori T, Arai N, Mizutani T, Hirose T. Glial cytoplasmic inclusions and tissue injury in multiple system atrophy: A quantitative study in white matter (olivopontocerebellar system) and gray matter (nigrostriatal system). Neuropathology 2008; 28: 249-257.
    • (2008) Neuropathology , vol.28 , pp. 249-257
    • Ishizawa, K.1    Komori, T.2    Arai, N.3    Mizutani, T.4    Hirose, T.5
  • 54
    • 0025359394 scopus 로고
    • Cytoplasmic argyrophilic inclusions in neurons of pontine nuclei in patients with olivopontocerebellar atrophy: immunohistochemical and ultrastructural studies
    • Kato S, Nakamura H. Cytoplasmic argyrophilic inclusions in neurons of pontine nuclei in patients with olivopontocerebellar atrophy: immunohistochemical and ultrastructural studies. Acta Neuropathol (Berl) 1990; 79: 584-594.
    • (1990) Acta Neuropathol (Berl) , vol.79 , pp. 584-594
    • Kato, S.1    Nakamura, H.2
  • 56
    • 0026543706 scopus 로고
    • Accumulation of tubular structures in oligodendroglial and neuronal cells as the basic alteration in multiple system atrophy
    • Papp MI, Lantos PL. Accumulation of tubular structures in oligodendroglial and neuronal cells as the basic alteration in multiple system atrophy. J Neurol Sci 1992; 107: 172-182.
    • (1992) J Neurol Sci , vol.107 , pp. 172-182
    • Papp, M.I.1    Lantos, P.L.2
  • 57
    • 0032584686 scopus 로고    scopus 로고
    • Filamentous alpha-synuclein inclusions link multiple system atrophy with Parkinson's disease and dementia with Lewy bodies
    • Spillantini MG, Crowther RA, Jakes R, Cairns NJ, Lantos PL, Goedert M. Filamentous alpha-synuclein inclusions link multiple system atrophy with Parkinson's disease and dementia with Lewy bodies. Neurosci Lett 1998; 251: 205-208.
    • (1998) Neurosci Lett , vol.251 , pp. 205-208
    • Spillantini, M.G.1    Crowther, R.A.2    Jakes, R.3    Cairns, N.J.4    Lantos, P.L.5    Goedert, M.6
  • 58
    • 0030915893 scopus 로고    scopus 로고
    • The distribution and dynamic density of oligodendroglial cytoplasmic inclusions (GCIs) in multiple system atrophy: a correlation between the density of GCIs and the degree of involvement of striatonigral and olivopontocerebellar systems
    • Inoue M, Yagishita S, Ryo M, Hasegawa K, Amano N, Matsushita M. The distribution and dynamic density of oligodendroglial cytoplasmic inclusions (GCIs) in multiple system atrophy: a correlation between the density of GCIs and the degree of involvement of striatonigral and olivopontocerebellar systems. Acta Neuropathol (Berl) 1997; 93: 585-591.
    • (1997) Acta Neuropathol (Berl) , vol.93 , pp. 585-591
    • Inoue, M.1    Yagishita, S.2    Ryo, M.3    Hasegawa, K.4    Amano, N.5    Matsushita, M.6
  • 59
    • 0032546895 scopus 로고    scopus 로고
    • Alpha-synuclein immunoreactivity in glial cytoplasmic inclusions in multiple system atrophy
    • Wakabayashi K, Yoshimoto M, Tsuji S, Takahashi H. Alpha-synuclein immunoreactivity in glial cytoplasmic inclusions in multiple system atrophy. Neurosci Lett 1998; 249: 180-182.
    • (1998) Neurosci Lett , vol.249 , pp. 180-182
    • Wakabayashi, K.1    Yoshimoto, M.2    Tsuji, S.3    Takahashi, H.4
  • 60
    • 33746108503 scopus 로고    scopus 로고
    • Cellular pathology in multiple system atrophy
    • Wakabayashi K, Takahashi H. Cellular pathology in multiple system atrophy. Neuropathology 2006; 26: 338-345.
    • (2006) Neuropathology , vol.26 , pp. 338-345
    • Wakabayashi, K.1    Takahashi, H.2
  • 61
    • 0031564828 scopus 로고    scopus 로고
    • Tau protein in the glial cytoplasmic inclusions of multiple system atrophy can be distinguished from abnormal tau in Alzheimer's disease
    • Cairns NJ, Atkinson PF, Hanger DP, Anderton BH, Daniel SE, Lantos PL. Tau protein in the glial cytoplasmic inclusions of multiple system atrophy can be distinguished from abnormal tau in Alzheimer's disease. Neurosci Lett 1997; 230: 49-52.
    • (1997) Neurosci Lett , vol.230 , pp. 49-52
    • Cairns, N.J.1    Atkinson, P.F.2    Hanger, D.P.3    Anderton, B.H.4    Daniel, S.E.5    Lantos, P.L.6
  • 63
    • 0026572153 scopus 로고
    • Immunocytochemical and ultrastructural studies of neuronal and oligodendroglial cytoplasmic inclusions in multiple system atrophy
    • Arima K, Murayama S, Mukoyama M, Inose T. Immunocytochemical and ultrastructural studies of neuronal and oligodendroglial cytoplasmic inclusions in multiple system atrophy. 1. Neuronal cytoplasmic inclusions. Acta Neuropathol (Berl) 1992; 83: 453-460.
    • (1992) 1. Neuronal cytoplasmic inclusions. Acta Neuropathol (Berl) , vol.83 , pp. 453-460
    • Arima, K.1    Murayama, S.2    Mukoyama, M.3    Inose, T.4
  • 64
    • 66949152096 scopus 로고    scopus 로고
    • Parkinson's disease
    • Lees AJ, Hardy J, Revesz T. Parkinson's disease. Lancet 2009; 373: 2055-2066.
    • (2009) Lancet , vol.373 , pp. 2055-2066
    • Lees, A.J.1    Hardy, J.2    Revesz, T.3
  • 65
    • 0035163412 scopus 로고    scopus 로고
    • The solubility of alphasynuclein in multiple system atrophy differs from that of dementia with Lewy bodies and Parkinson's disease
    • Campbell BC, McLean CA, Culvenor JG et al. The solubility of alphasynuclein in multiple system atrophy differs from that of dementia with Lewy bodies and Parkinson's disease. J Neurochem 2001; 76: 87-96.
    • (2001) J Neurochem , vol.76 , pp. 87-96
    • Campbell, B.C.1    McLean, C.A.2    Culvenor, J.G.3
  • 66
    • 0032833653 scopus 로고    scopus 로고
    • Widespread alterations of alpha-synuclein in multiple system atrophy
    • Dickson DW, Liu W, Hardy J et al. Widespread alterations of alpha-synuclein in multiple system atrophy. Am J Pathol 1999; 155: 1241-1251.
    • (1999) Am J Pathol , vol.155 , pp. 1241-1251
    • Dickson, D.W.1    Liu, W.2    Hardy, J.3
  • 67
    • 0036174010 scopus 로고    scopus 로고
    • Alpha-synuclein is phosphorylated in synucleinopathy lesions
    • Fujiwara H, Hasegawa M, Dohmae N et al. Alpha-synuclein is phosphorylated in synucleinopathy lesions. Nat Cell Biol 2002; 4: 160-164.
    • (2002) Nat Cell Biol , vol.4 , pp. 160-164
    • Fujiwara, H.1    Hasegawa, M.2    Dohmae, N.3
  • 68
    • 0033678217 scopus 로고    scopus 로고
    • Widespread nitration of pathological inclusions in neurodegenerative synucleinopathies
    • Duda JE, Giasson BI, Chen Q et al. Widespread nitration of pathological inclusions in neurodegenerative synucleinopathies. Am J Pathol 2000; 157: 1439-1445.
    • (2000) Am J Pathol , vol.157 , pp. 1439-1445
    • Duda, J.E.1    Giasson, B.I.2    Chen, Q.3
  • 69
    • 0033800039 scopus 로고    scopus 로고
    • Immunohistochemical and biochemical studies demonstrate a distinct profile of alpha-synuclein permutations in multiple system atrophy
    • Duda JE, Giasson BI, Gur TL et al. Immunohistochemical and biochemical studies demonstrate a distinct profile of alpha-synuclein permutations in multiple system atrophy. J Neuropathol Exp Neurol 2000; 59: 830-841.
    • (2000) J Neuropathol Exp Neurol , vol.59 , pp. 830-841
    • Duda, J.E.1    Giasson, B.I.2    Gur, T.L.3
  • 70
    • 0034602442 scopus 로고    scopus 로고
    • Oxidative damage linked to neurodegeneration by selective alpha-synuclein nitration in synucleinopathy lesions
    • Giasson BI, Duda JE, Murray IV et al. Oxidative damage linked to neurodegeneration by selective alpha-synuclein nitration in synucleinopathy lesions. Science 2000; 290: 985-989.
    • (2000) Science , vol.290 , pp. 985-989
    • Giasson, B.I.1    Duda, J.E.2    Murray, I.V.3
  • 71
    • 61549111872 scopus 로고    scopus 로고
    • Alpha-synuclein and neuronal cell death
    • Cookson MR. Alpha-synuclein and neuronal cell death. Mol Neurodegener 2009; 4: 9-23.
    • (2009) Mol Neurodegener , vol.4 , pp. 9-23
    • Cookson, M.R.1
  • 73
    • 0028941637 scopus 로고
    • Autonomic dysfunction in pathologically confirmed multiple system atrophy and idiopathic Parkinson's disease-a retrospective comparison
    • Magalhaes M, Wenning GK, Daniel SE, Quinn NP. Autonomic dysfunction in pathologically confirmed multiple system atrophy and idiopathic Parkinson's disease-a retrospective comparison. Acta Neurol Scand 1995; 91: 98-102.
    • (1995) Acta Neurol Scand , vol.91 , pp. 98-102
    • Magalhaes, M.1    Wenning, G.K.2    Daniel, S.E.3    Quinn, N.P.4
  • 74
    • 67049100869 scopus 로고    scopus 로고
    • Prospective differentiation of multiple system atrophy from Parkinson disease, with and without autonomic failure
    • Lipp A, Sandroni P, Ahlskog JE et al. Prospective differentiation of multiple system atrophy from Parkinson disease, with and without autonomic failure. Arch Neurol 2009; 66: 742-750.
    • (2009) Arch Neurol , vol.66 , pp. 742-750
    • Lipp, A.1    Sandroni, P.2    Ahlskog, J.E.3
  • 75
    • 70449518182 scopus 로고    scopus 로고
    • Concomitant progressive supranuclear palsy and multiple system atrophy: more than a simple twist of fate?
    • Silveira-Moriyama L, González AM, O'Sullivan SS et al. Concomitant progressive supranuclear palsy and multiple system atrophy: more than a simple twist of fate? Neurosci Lett 2009; 467: 208-211.
    • (2009) Neurosci Lett , vol.467 , pp. 208-211
    • Silveira-Moriyama, L.1    González, A.M.2    O'Sullivan, S.S.3
  • 76
    • 49049110031 scopus 로고    scopus 로고
    • Glial cytoplasmic inclusions in neurologically normal elderly: prodromal multiple system atrophy?
    • Fujishiro H, Ahn TB, Frigerio R et al. Glial cytoplasmic inclusions in neurologically normal elderly: prodromal multiple system atrophy? Acta Neuropathol 2008; 116: 269-275.
    • (2008) Acta Neuropathol , vol.116 , pp. 269-275
    • Fujishiro, H.1    Ahn, T.B.2    Frigerio, R.3
  • 78
    • 70449478417 scopus 로고    scopus 로고
    • Mitochondrial inhibitor 3-nitroproprionic acid enhances oxidative modification of alpha-synuclein in a transgenic mouse model of multiple system atrophy
    • Ubhi K, Lee PH, Adame A et al. Mitochondrial inhibitor 3-nitroproprionic acid enhances oxidative modification of alpha-synuclein in a transgenic mouse model of multiple system atrophy. J Neurosci Res 2009; 87: 2728-2739.
    • (2009) J Neurosci Res , vol.87 , pp. 2728-2739
    • Ubhi, K.1    Lee, P.H.2    Adame, A.3
  • 79
    • 0033774686 scopus 로고    scopus 로고
    • Alphasynuclein is developmentally expressed in cultured rat brain oligodendrocytes
    • Richter-Landsberg C, Gorath M, Trojanowski JQ, Lee VM. Alphasynuclein is developmentally expressed in cultured rat brain oligodendrocytes. J Neurosci Res 2000; 62: 9-14.
    • (2000) J Neurosci Res , vol.62 , pp. 9-14
    • Richter-Landsberg, C.1    Gorath, M.2    Trojanowski, J.Q.3    Lee, V.M.4
  • 81
    • 35348909482 scopus 로고    scopus 로고
    • p25alpha relocalizes in oligodendroglia from myelin to cytoplasmic inclusions in multiple system atrophy
    • Song YJ, Lundvig DM, Huang Y et al. p25alpha relocalizes in oligodendroglia from myelin to cytoplasmic inclusions in multiple system atrophy. Am J Pathol 2007; 171: 1291-1303.
    • (2007) Am J Pathol , vol.171 , pp. 1291-1303
    • Song, Y.J.1    Lundvig, D.M.2    Huang, Y.3
  • 82
    • 56749152384 scopus 로고    scopus 로고
    • LRRK2 and parkin immunoreactivity in multiple system atrophy inclusions
    • Huang Y, Song YJ, Murphy K et al. LRRK2 and parkin immunoreactivity in multiple system atrophy inclusions. Acta Neuropathol 2008; 116: 639-646.
    • (2008) Acta Neuropathol , vol.116 , pp. 639-646
    • Huang, Y.1    Song, Y.J.2    Murphy, K.3
  • 84
    • 36949032824 scopus 로고    scopus 로고
    • Microglial activation mediates neurodegeneration related to oligodendroglial alpha-synucleinopathy: implications for multiple system atrophy
    • Stefanova N, Reindl M, Neumann M, Kahle PJ, Poewe W, Wenning GK. Microglial activation mediates neurodegeneration related to oligodendroglial alpha-synucleinopathy: implications for multiple system atrophy. Mov Disord 2007; 22: 2196-2203.
    • (2007) Mov Disord , vol.22 , pp. 2196-2203
    • Stefanova, N.1    Reindl, M.2    Neumann, M.3    Kahle, P.J.4    Poewe, W.5    Wenning, G.K.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.