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Volumn 8, Issue 12, 2009, Pages 1172-1178

Multiple system atrophy: an update

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA SYNUCLEIN; MINOCYCLINE; RASAGILINE; RIFAMPICIN; RILUZOLE;

EID: 71849092562     PISSN: 14744422     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1474-4422(09)70288-1     Document Type: Review
Times cited : (321)

References (65)
  • 1
    • 0014469501 scopus 로고
    • Orthostatic hypotension and nicotine sensitivity in a case of multiple system atrophy
    • Graham J.G., and Oppenheimer D.R. Orthostatic hypotension and nicotine sensitivity in a case of multiple system atrophy. J Neurol Neurosurg Psychiatry 32 (1969) 28-34
    • (1969) J Neurol Neurosurg Psychiatry , vol.32 , pp. 28-34
    • Graham, J.G.1    Oppenheimer, D.R.2
  • 2
    • 0024843373 scopus 로고
    • Glial cytoplasmic inclusions in the CNS of patients with multiple system atrophy (striatonigral degeneration, olivopontocerebellar atrophy and Shy-Drager syndrome)
    • Papp M.I., Kahn J.E., and Lantos P.L. Glial cytoplasmic inclusions in the CNS of patients with multiple system atrophy (striatonigral degeneration, olivopontocerebellar atrophy and Shy-Drager syndrome). J Neurol Sci 94 (1989) 79-100
    • (1989) J Neurol Sci , vol.94 , pp. 79-100
    • Papp, M.I.1    Kahn, J.E.2    Lantos, P.L.3
  • 3
    • 0032584686 scopus 로고    scopus 로고
    • Filamentous alpha-synuclein inclusions link multiple system atrophy with Parkinson's disease and dementia with Lewy bodies
    • Spillantini M.G., Crowther R.A., Jakes R., et al. Filamentous alpha-synuclein inclusions link multiple system atrophy with Parkinson's disease and dementia with Lewy bodies. Neurosci Lett 251 (1998) 205-208
    • (1998) Neurosci Lett , vol.251 , pp. 205-208
    • Spillantini, M.G.1    Crowther, R.A.2    Jakes, R.3
  • 4
    • 0032546895 scopus 로고    scopus 로고
    • Alpha-synuclein immunoreactivity in glial cytoplasmic inclusions in multiple system atrophy
    • Wakabayashi K., Yoshimoto M., Tsuji S., and Takahashi H. Alpha-synuclein immunoreactivity in glial cytoplasmic inclusions in multiple system atrophy. Neurosci Lett 249 (1998) 180-182
    • (1998) Neurosci Lett , vol.249 , pp. 180-182
    • Wakabayashi, K.1    Yoshimoto, M.2    Tsuji, S.3    Takahashi, H.4
  • 5
    • 35848966786 scopus 로고    scopus 로고
    • Protein aggregation mechanisms in synucleinopathies: commonalities and differences
    • Beyer K., and Ariza A. Protein aggregation mechanisms in synucleinopathies: commonalities and differences. J Neuropathol Exp Neurol 66 (2007) 965-974
    • (2007) J Neuropathol Exp Neurol , vol.66 , pp. 965-974
    • Beyer, K.1    Ariza, A.2
  • 6
    • 0032435329 scopus 로고    scopus 로고
    • Consensus statement on the diagnosis of multiple system atrophy. American Autonomic Society and American Academy of Neurology
    • Gilman S., Low P., Quinn N., et al. Consensus statement on the diagnosis of multiple system atrophy. American Autonomic Society and American Academy of Neurology. Clin Auton Res 8 (1998) 359-362
    • (1998) Clin Auton Res , vol.8 , pp. 359-362
    • Gilman, S.1    Low, P.2    Quinn, N.3
  • 7
    • 19944428639 scopus 로고    scopus 로고
    • Development and validation of the unified multiple system atrophy rating scale (UMSARS)
    • Wenning G.K., Tison F., Seppi K., et al. Development and validation of the unified multiple system atrophy rating scale (UMSARS). Mov Disord 19 (2004) 1391-1402
    • (2004) Mov Disord , vol.19 , pp. 1391-1402
    • Wenning, G.K.1    Tison, F.2    Seppi, K.3
  • 8
    • 52449086856 scopus 로고    scopus 로고
    • Second consensus statement on the diagnosis of multiple system atrophy
    • Gilman S., Wenning G.K., Low P.A., et al. Second consensus statement on the diagnosis of multiple system atrophy. Neurology 71 (2008) 670-676
    • (2008) Neurology , vol.71 , pp. 670-676
    • Gilman, S.1    Wenning, G.K.2    Low, P.A.3
  • 9
    • 0030695277 scopus 로고    scopus 로고
    • Incidence of progressive supranuclear palsy and multiple system atrophy in Olmsted County, Minnesota, 1976 to 1990
    • Bower J.H., Maraganore D.M., McDonnell S.K., and Rocca W.A. Incidence of progressive supranuclear palsy and multiple system atrophy in Olmsted County, Minnesota, 1976 to 1990. Neurology 49 (1997) 1284-1288
    • (1997) Neurology , vol.49 , pp. 1284-1288
    • Bower, J.H.1    Maraganore, D.M.2    McDonnell, S.K.3    Rocca, W.A.4
  • 11
    • 34548182758 scopus 로고    scopus 로고
    • Features of probable multiple system atrophy patients identified among 4770 patients with parkinsonism enrolled in the multicentre registry of the German Competence Network on Parkinson's disease
    • Wullner U., Schmitz-Hubsch T., Abele M., et al. Features of probable multiple system atrophy patients identified among 4770 patients with parkinsonism enrolled in the multicentre registry of the German Competence Network on Parkinson's disease. J Neural Transm 114 (2007) 1161-1165
    • (2007) J Neural Transm , vol.114 , pp. 1161-1165
    • Wullner, U.1    Schmitz-Hubsch, T.2    Abele, M.3
  • 13
    • 33644947758 scopus 로고    scopus 로고
    • Progression of multiple system atrophy (MSA): a prospective natural history study by the European MSA Study Group (EMSA SG)
    • Geser F., Wenning G.K., Seppi K., et al. Progression of multiple system atrophy (MSA): a prospective natural history study by the European MSA Study Group (EMSA SG). Mov Disord 21 (2006) 179-186
    • (2006) Mov Disord , vol.21 , pp. 179-186
    • Geser, F.1    Wenning, G.K.2    Seppi, K.3
  • 14
    • 38549085666 scopus 로고    scopus 로고
    • Potential outcome measures and trial design issues for multiple system atrophy
    • May S., Gilman S., Sowell B.B., et al. Potential outcome measures and trial design issues for multiple system atrophy. Mov Disord 22 (2007) 2371-2377
    • (2007) Mov Disord , vol.22 , pp. 2371-2377
    • May, S.1    Gilman, S.2    Sowell, B.B.3
  • 15
    • 33750502211 scopus 로고    scopus 로고
    • MSA-C is the predominant clinical phenotype of MSA in Japan: analysis of 142 patients with probable MSA
    • Yabe I., Soma H., Takei A., et al. MSA-C is the predominant clinical phenotype of MSA in Japan: analysis of 142 patients with probable MSA. J Neurol Sci 249 (2006) 115-121
    • (2006) J Neurol Sci , vol.249 , pp. 115-121
    • Yabe, I.1    Soma, H.2    Takei, A.3
  • 16
    • 13144254238 scopus 로고    scopus 로고
    • Progression of parkinsonism in multiple system atrophy
    • Seppi K., Yekhlef F., Diem A., et al. Progression of parkinsonism in multiple system atrophy. J Neurol 252 (2005) 91-96
    • (2005) J Neurol , vol.252 , pp. 91-96
    • Seppi, K.1    Yekhlef, F.2    Diem, A.3
  • 17
    • 33646570005 scopus 로고    scopus 로고
    • Progression of putaminal degeneration in multiple system atrophy: a serial diffusion MR study
    • Seppi K., Schocke M.F., Mair K.J., et al. Progression of putaminal degeneration in multiple system atrophy: a serial diffusion MR study. Neuroimage 31 (2006) 240-245
    • (2006) Neuroimage , vol.31 , pp. 240-245
    • Seppi, K.1    Schocke, M.F.2    Mair, K.J.3
  • 18
    • 33847663461 scopus 로고    scopus 로고
    • Progression of brain atrophy in multiple system atrophy. A longitudinal VBM study
    • Brenneis C., Egger K., Scherfler C., et al. Progression of brain atrophy in multiple system atrophy. A longitudinal VBM study. J Neurol 254 (2007) 191-196
    • (2007) J Neurol , vol.254 , pp. 191-196
    • Brenneis, C.1    Egger, K.2    Scherfler, C.3
  • 19
    • 33846179348 scopus 로고    scopus 로고
    • Progression of dysautonomia in multiple system atrophy: a prospective study of self-perceived impairment
    • Kollensperger M., Stampfer-Kountchev M., Seppi K., et al. Progression of dysautonomia in multiple system atrophy: a prospective study of self-perceived impairment. Eur J Neurol 14 (2007) 66-72
    • (2007) Eur J Neurol , vol.14 , pp. 66-72
    • Kollensperger, M.1    Stampfer-Kountchev, M.2    Seppi, K.3
  • 20
    • 33846997570 scopus 로고    scopus 로고
    • Early development of autonomic dysfunction may predict poor prognosis in patients with multiple system atrophy
    • Tada M., Onodera O., Tada M., et al. Early development of autonomic dysfunction may predict poor prognosis in patients with multiple system atrophy. Arch Neurol 64 (2007) 256-260
    • (2007) Arch Neurol , vol.64 , pp. 256-260
    • Tada, M.1    Onodera, O.2    Tada, M.3
  • 21
    • 44949211482 scopus 로고    scopus 로고
    • Clinical outcomes of progressive supranuclear palsy and multiple system atrophy
    • O'Sullivan S.S., Massey L.A., Williams D.R., et al. Clinical outcomes of progressive supranuclear palsy and multiple system atrophy. Brain 131 (2008) 1362-1372
    • (2008) Brain , vol.131 , pp. 1362-1372
    • O'Sullivan, S.S.1    Massey, L.A.2    Williams, D.R.3
  • 22
    • 27744545323 scopus 로고    scopus 로고
    • The European Multiple System Atrophy-Study Group (EMSA-SG)
    • Geser F., Seppi K., Stampfer-Kountchev M., et al. The European Multiple System Atrophy-Study Group (EMSA-SG). J Neural Transm 112 (2005) 1677-1686
    • (2005) J Neural Transm , vol.112 , pp. 1677-1686
    • Geser, F.1    Seppi, K.2    Stampfer-Kountchev, M.3
  • 23
    • 71849114954 scopus 로고    scopus 로고
    • Evaluation of diagnostic and therapeutic standards for MSA in Europe: first results from the European MSA Registry (EMSA-R)
    • Stampfer-Kountchev M., Geser F., Ndayisaba J.P., et al. Evaluation of diagnostic and therapeutic standards for MSA in Europe: first results from the European MSA Registry (EMSA-R). Mov Disord 20 suppl 12 (2005) S144
    • (2005) Mov Disord , vol.20 , Issue.SUPPL. 12
    • Stampfer-Kountchev, M.1    Geser, F.2    Ndayisaba, J.P.3
  • 24
    • 35948994645 scopus 로고    scopus 로고
    • Proposed neuropathological criteria for the post mortem diagnosis of multiple system atrophy
    • Trojanowski J.Q., and Revesz T. Proposed neuropathological criteria for the post mortem diagnosis of multiple system atrophy. Neuropathol Appl Neurobiol 33 (2007) 615-620
    • (2007) Neuropathol Appl Neurobiol , vol.33 , pp. 615-620
    • Trojanowski, J.Q.1    Revesz, T.2
  • 25
    • 39749123263 scopus 로고    scopus 로고
    • Axonal alpha-synuclein aggregates herald centripetal degeneration of cardiac sympathetic nerve in Parkinson's disease
    • Orimo S., Uchihara T., Nakamura A., et al. Axonal alpha-synuclein aggregates herald centripetal degeneration of cardiac sympathetic nerve in Parkinson's disease. Brain 131 (2008) 642-650
    • (2008) Brain , vol.131 , pp. 642-650
    • Orimo, S.1    Uchihara, T.2    Nakamura, A.3
  • 26
    • 33645093700 scopus 로고    scopus 로고
    • Pathology of the sympathetic nervous system corresponding to the decreased cardiac uptake in 123I-metaiodobenzylguanidine (MIBG) scintigraphy in a patient with Parkinson disease
    • Mitsui J., Saito Y., Momose T., et al. Pathology of the sympathetic nervous system corresponding to the decreased cardiac uptake in 123I-metaiodobenzylguanidine (MIBG) scintigraphy in a patient with Parkinson disease. J Neurol Sci 243 (2006) 101-104
    • (2006) J Neurol Sci , vol.243 , pp. 101-104
    • Mitsui, J.1    Saito, Y.2    Momose, T.3
  • 27
    • 43749105831 scopus 로고    scopus 로고
    • 123I-MIBG cardiac scintigraphy provides clues to the underlying neurodegenerative disorder in idiopathic REM sleep behavior disorder
    • Miyamoto T., Miyamoto M., Suzuki K., et al. 123I-MIBG cardiac scintigraphy provides clues to the underlying neurodegenerative disorder in idiopathic REM sleep behavior disorder. Sleep 31 (2008) 717-723
    • (2008) Sleep , vol.31 , pp. 717-723
    • Miyamoto, T.1    Miyamoto, M.2    Suzuki, K.3
  • 28
    • 69949158515 scopus 로고    scopus 로고
    • MIBG scintigraphy for differentiating Parkinson's disease with autonomic dysfunction from Parkinsonism-predominant multiple system atrophy
    • Chung E.J., Lee W.Y., Yoon W.T., Kim B.J., and Lee G.H. MIBG scintigraphy for differentiating Parkinson's disease with autonomic dysfunction from Parkinsonism-predominant multiple system atrophy. Mov Disord 24 (2009) 1650-1655
    • (2009) Mov Disord , vol.24 , pp. 1650-1655
    • Chung, E.J.1    Lee, W.Y.2    Yoon, W.T.3    Kim, B.J.4    Lee, G.H.5
  • 29
    • 67651146706 scopus 로고    scopus 로고
    • Proposed neuroimaging criteria for the diagnosis of multiple system atrophy
    • Brooks D.J., and Seppi K. Proposed neuroimaging criteria for the diagnosis of multiple system atrophy. Mov Disord 24 (2009) 949-964
    • (2009) Mov Disord , vol.24 , pp. 949-964
    • Brooks, D.J.1    Seppi, K.2
  • 30
    • 10344260246 scopus 로고    scopus 로고
    • The spectrum of pathological involvement of the striatonigral and olivopontocerebellar systems in multiple system atrophy: clinicopathological correlations
    • Ozawa T., Paviour D., Quinn N.P., et al. The spectrum of pathological involvement of the striatonigral and olivopontocerebellar systems in multiple system atrophy: clinicopathological correlations. Brain 127 (2004) 2657-2671
    • (2004) Brain , vol.127 , pp. 2657-2671
    • Ozawa, T.1    Paviour, D.2    Quinn, N.P.3
  • 31
    • 26444610170 scopus 로고    scopus 로고
    • Grading of neuropathology in multiple system atrophy: proposal for a novel scale
    • Jellinger K.A., Seppi K., and Wenning G.K. Grading of neuropathology in multiple system atrophy: proposal for a novel scale. Mov Disord 20 suppl 12 (2005) S29-S36
    • (2005) Mov Disord , vol.20 , Issue.SUPPL. 12
    • Jellinger, K.A.1    Seppi, K.2    Wenning, G.K.3
  • 32
    • 10244264868 scopus 로고    scopus 로고
    • TPPP/p25: from unfolded protein to misfolding disease: prediction and experiments
    • Orosz F., Kovacs G.G., Lehotzky A., et al. TPPP/p25: from unfolded protein to misfolding disease: prediction and experiments. Biol Cell 96 (2004) 701-711
    • (2004) Biol Cell , vol.96 , pp. 701-711
    • Orosz, F.1    Kovacs, G.G.2    Lehotzky, A.3
  • 33
    • 35348909482 scopus 로고    scopus 로고
    • p25alpha relocalizes in oligodendroglia from myelin to cytoplasmic inclusions in multiple system atrophy
    • Song Y.J., Lundvig D.M., Huang Y., et al. p25alpha relocalizes in oligodendroglia from myelin to cytoplasmic inclusions in multiple system atrophy. Am J Pathol 171 (2007) 1291-1303
    • (2007) Am J Pathol , vol.171 , pp. 1291-1303
    • Song, Y.J.1    Lundvig, D.M.2    Huang, Y.3
  • 34
    • 20044383388 scopus 로고    scopus 로고
    • p25alpha stimulates alpha-synuclein aggregation and is co-localized with aggregated alpha-synuclein in alpha-synucleinopathies
    • Lindersson E., Lundvig D., Petersen C., et al. p25alpha stimulates alpha-synuclein aggregation and is co-localized with aggregated alpha-synuclein in alpha-synucleinopathies. J Biol Chem 280 (2005) 5703-5715
    • (2005) J Biol Chem , vol.280 , pp. 5703-5715
    • Lindersson, E.1    Lundvig, D.2    Petersen, C.3
  • 36
    • 34648813113 scopus 로고    scopus 로고
    • Multiple system atrophy: alpha-synuclein and neuronal degeneration
    • Yoshida M. Multiple system atrophy: alpha-synuclein and neuronal degeneration. Neuropathology 27 (2007) 484-493
    • (2007) Neuropathology , vol.27 , pp. 484-493
    • Yoshida, M.1
  • 37
    • 35948994645 scopus 로고    scopus 로고
    • Proposed neuropathological criteria for the post mortem diagnosis of multiple system atrophy
    • Trojanowski J.Q., and Revesz T. Proposed neuropathological criteria for the post mortem diagnosis of multiple system atrophy. Neuropathol Appl Neurobiol 33 (2007) 615-620
    • (2007) Neuropathol Appl Neurobiol , vol.33 , pp. 615-620
    • Trojanowski, J.Q.1    Revesz, T.2
  • 38
    • 24344475263 scopus 로고    scopus 로고
    • An autopsy case of early ("minimal change") olivopontocerebellar atrophy (multiple system atrophy-cerebellar)
    • Wakabayashi K., Mori F., Nishie M., et al. An autopsy case of early ("minimal change") olivopontocerebellar atrophy (multiple system atrophy-cerebellar). Acta Neuropathol 110 (2005) 185-190
    • (2005) Acta Neuropathol , vol.110 , pp. 185-190
    • Wakabayashi, K.1    Mori, F.2    Nishie, M.3
  • 39
    • 7044226609 scopus 로고    scopus 로고
    • A quantitative investigation of neuronal cytoplasmic and intranuclear inclusions in the pontine and inferior olivary nuclei in multiple system atrophy
    • Nishie M., Mori F., Yoshimoto M., Takahashi H., and Wakabayashi K. A quantitative investigation of neuronal cytoplasmic and intranuclear inclusions in the pontine and inferior olivary nuclei in multiple system atrophy. Neuropathol Appl Neurobiol 30 (2004) 546-554
    • (2004) Neuropathol Appl Neurobiol , vol.30 , pp. 546-554
    • Nishie, M.1    Mori, F.2    Yoshimoto, M.3    Takahashi, H.4    Wakabayashi, K.5
  • 40
    • 33646175559 scopus 로고    scopus 로고
    • p25alpha immunoreactive but alpha-synuclein immunonegative neuronal inclusions in multiple system atrophy
    • Baker K.G., Huang Y., McCann H., Gai W.P., Jensen P.H., and Halliday G.M. p25alpha immunoreactive but alpha-synuclein immunonegative neuronal inclusions in multiple system atrophy. Acta Neuropathol 111 (2006) 193-235
    • (2006) Acta Neuropathol , vol.111 , pp. 193-235
    • Baker, K.G.1    Huang, Y.2    McCann, H.3    Gai, W.P.4    Jensen, P.H.5    Halliday, G.M.6
  • 41
    • 29144435092 scopus 로고    scopus 로고
    • Heredity in multiple system atrophy
    • Soma H., Yabe I., Takei A., et al. Heredity in multiple system atrophy. J Neurol Sci 240 (2006) 107-110
    • (2006) J Neurol Sci , vol.240 , pp. 107-110
    • Soma, H.1    Yabe, I.2    Takei, A.3
  • 43
    • 67249139655 scopus 로고    scopus 로고
    • SNCA variants are associated with increased risk for multiple system atrophy
    • Scholz S.W., Houlden H., Schulte C., et al. SNCA variants are associated with increased risk for multiple system atrophy. Ann Neurol 65 (2009) 610-614
    • (2009) Ann Neurol , vol.65 , pp. 610-614
    • Scholz, S.W.1    Houlden, H.2    Schulte, C.3
  • 44
    • 70349578343 scopus 로고    scopus 로고
    • Genetic variants of the alpha-synuclein gene SNCA are associated with multiple system atrophy
    • Al-Chalabi A., Durr A., Wood N.W., et al. Genetic variants of the alpha-synuclein gene SNCA are associated with multiple system atrophy. PLoS One 4 (2009) e7114
    • (2009) PLoS One , vol.4
    • Al-Chalabi, A.1    Durr, A.2    Wood, N.W.3
  • 45
    • 27744516098 scopus 로고    scopus 로고
    • Epidemiological evidence on multiple system atrophy
    • Vanacore N. Epidemiological evidence on multiple system atrophy. J Neural Transm 112 (2005) 1605-1612
    • (2005) J Neural Transm , vol.112 , pp. 1605-1612
    • Vanacore, N.1
  • 46
    • 48649109438 scopus 로고    scopus 로고
    • Risk factors of multiple system atrophy: a case-control study in French patients
    • Vidal J.S., Vidailhet M., Elbaz A., et al. Risk factors of multiple system atrophy: a case-control study in French patients. Mov Disord 23 (2008) 797-803
    • (2008) Mov Disord , vol.23 , pp. 797-803
    • Vidal, J.S.1    Vidailhet, M.2    Elbaz, A.3
  • 47
    • 15444376598 scopus 로고    scopus 로고
    • Mouse model of multiple system atrophy alpha-synuclein expression in oligodendrocytes causes glial and neuronal degeneration
    • Yazawa I., Giasson B.I., Sasaki R., et al. Mouse model of multiple system atrophy alpha-synuclein expression in oligodendrocytes causes glial and neuronal degeneration. Neuron 45 (2005) 847-859
    • (2005) Neuron , vol.45 , pp. 847-859
    • Yazawa, I.1    Giasson, B.I.2    Sasaki, R.3
  • 48
    • 27944436033 scopus 로고    scopus 로고
    • Neurological and neurodegenerative alterations in a transgenic mouse model expressing human alpha-synuclein under oligodendrocyte promoter: implications for multiple system atrophy
    • Shults C.W., Rockenstein E., Crews L., et al. Neurological and neurodegenerative alterations in a transgenic mouse model expressing human alpha-synuclein under oligodendrocyte promoter: implications for multiple system atrophy. J Neurosci 25 (2005) 10689-10699
    • (2005) J Neurosci , vol.25 , pp. 10689-10699
    • Shults, C.W.1    Rockenstein, E.2    Crews, L.3
  • 49
    • 36949032824 scopus 로고    scopus 로고
    • Microglial activation mediates neurodegeneration related to oligodendroglial alpha-synucleinopathy: implications for multiple system atrophy
    • Stefanova N., Reindl M., Neumann M., et al. Microglial activation mediates neurodegeneration related to oligodendroglial alpha-synucleinopathy: implications for multiple system atrophy. Mov Disord 22 (2007) 2196-3003
    • (2007) Mov Disord , vol.22 , pp. 2196-3003
    • Stefanova, N.1    Reindl, M.2    Neumann, M.3
  • 50
    • 14644417871 scopus 로고    scopus 로고
    • Oxidative stress in transgenic mice with oligodendroglial alpha-synuclein overexpression replicates the characteristic neuropathology of multiple system atrophy
    • Stefanova N., Reindl M., Neumann M., et al. Oxidative stress in transgenic mice with oligodendroglial alpha-synuclein overexpression replicates the characteristic neuropathology of multiple system atrophy. Am J Pathol 166 (2005) 869-876
    • (2005) Am J Pathol , vol.166 , pp. 869-876
    • Stefanova, N.1    Reindl, M.2    Neumann, M.3
  • 51
    • 70449478417 scopus 로고    scopus 로고
    • Mitochondrial inhibitor 3-nitroproprionic acid enhances oxidative modification of alpha-synuclein in a transgenic mouse model of multiple system atrophy
    • Ubhi K., Lee P.H., Adame A., et al. Mitochondrial inhibitor 3-nitroproprionic acid enhances oxidative modification of alpha-synuclein in a transgenic mouse model of multiple system atrophy. J Neurosci Res 87 (2009) 2728-2739
    • (2009) J Neurosci Res , vol.87 , pp. 2728-2739
    • Ubhi, K.1    Lee, P.H.2    Adame, A.3
  • 52
    • 73449102917 scopus 로고    scopus 로고
    • Recent developments in multiple system atrophy
    • Wenning G.K., and Stefanova N. Recent developments in multiple system atrophy. J Neurol 256 (2009) 1791-1808
    • (2009) J Neurol , vol.256 , pp. 1791-1808
    • Wenning, G.K.1    Stefanova, N.2
  • 53
    • 34447105342 scopus 로고    scopus 로고
    • Safety and tolerability of growth hormone therapy in multiple system atrophy: a double-blind, placebo-controlled study
    • Holmberg B., Johansson J.O., Poewe W., et al. Safety and tolerability of growth hormone therapy in multiple system atrophy: a double-blind, placebo-controlled study. Mov Disord 22 (2007) 1138-1144
    • (2007) Mov Disord , vol.22 , pp. 1138-1144
    • Holmberg, B.1    Johansson, J.O.2    Poewe, W.3
  • 54
    • 58849122658 scopus 로고    scopus 로고
    • Riluzole treatment, survival and diagnostic criteria in Parkinson plus disorders: the NNIPPS study
    • Bensimon G., Ludolph A., Agid Y., et al. Riluzole treatment, survival and diagnostic criteria in Parkinson plus disorders: the NNIPPS study. Brain 132 (2009) 156-171
    • (2009) Brain , vol.132 , pp. 156-171
    • Bensimon, G.1    Ludolph, A.2    Agid, Y.3
  • 55
    • 61449173973 scopus 로고    scopus 로고
    • A randomized, double-blind, placebo-controlled, delayed start study to assess rasagiline as a disease modifying therapy in Parkinson's disease (the ADAGIO study): rationale, design, and baseline characteristics
    • Olanow C.W., Hauser R.A., Jankovic J., et al. A randomized, double-blind, placebo-controlled, delayed start study to assess rasagiline as a disease modifying therapy in Parkinson's disease (the ADAGIO study): rationale, design, and baseline characteristics. Mov Disord 23 (2008) 2194-2201
    • (2008) Mov Disord , vol.23 , pp. 2194-2201
    • Olanow, C.W.1    Hauser, R.A.2    Jankovic, J.3
  • 56
    • 70549112884 scopus 로고    scopus 로고
    • Rasagiline 1 mg/day provides benefits in the progression of non-motor symptoms in patients with early Parkinson's disease: assessment with the revised MDS-UPDRAS
    • ADAGIO Investigators
    • Poewe W., Hauser R.A., Lang A., and ADAGIO Investigators. Rasagiline 1 mg/day provides benefits in the progression of non-motor symptoms in patients with early Parkinson's disease: assessment with the revised MDS-UPDRAS. Mov Disord 24 (2009) S272-S273
    • (2009) Mov Disord , vol.24
    • Poewe, W.1    Hauser, R.A.2    Lang, A.3
  • 57
    • 71849085235 scopus 로고    scopus 로고
    • The effect of rasagiline in early Parkinson's disease (PD): the ADAGIO delayed start trial
    • Olanow CWl ADAGIO Investigators
    • Rascol O., and Olanow CWl ADAGIO Investigators. The effect of rasagiline in early Parkinson's disease (PD): the ADAGIO delayed start trial. Mov Disord 24 (2009) S275
    • (2009) Mov Disord , vol.24
    • Rascol, O.1
  • 58
    • 71849091195 scopus 로고    scopus 로고
    • Rasagiline provides benefits in the symptoms of fatigue in patients with early Parkinson's disease
    • ADAGIO Investigators
    • Stocchi F., and ADAGIO Investigators. Rasagiline provides benefits in the symptoms of fatigue in patients with early Parkinson's disease. Mov Disord 24 (2009) S280-S281
    • (2009) Mov Disord , vol.24
    • Stocchi, F.1
  • 59
    • 70349456475 scopus 로고    scopus 로고
    • A double-blind, delayed-start trial of rasagiline in Parkinson's disease
    • Olanow C.W., Rascol O., Hauser R., et al. A double-blind, delayed-start trial of rasagiline in Parkinson's disease. N Engl J Med 361 (2009) 1268-1278
    • (2009) N Engl J Med , vol.361 , pp. 1268-1278
    • Olanow, C.W.1    Rascol, O.2    Hauser, R.3
  • 60
    • 41149124377 scopus 로고    scopus 로고
    • Rasagiline is neuroprotective in a transgenic model of multiple system atrophy
    • Stefanova N., Poewe W., and Wenning G.K. Rasagiline is neuroprotective in a transgenic model of multiple system atrophy. Exp Neurol 210 (2008) 421-427
    • (2008) Exp Neurol , vol.210 , pp. 421-427
    • Stefanova, N.1    Poewe, W.2    Wenning, G.K.3
  • 61
    • 8844224948 scopus 로고    scopus 로고
    • Rifampicin inhibits alpha-synuclein fibrillation and disaggregates fibrils
    • Li J., Zhu M., Rajamani S., Uversky V.N., and Fink A.L. Rifampicin inhibits alpha-synuclein fibrillation and disaggregates fibrils. Chem Biol 11 (2004) 1513-1521
    • (2004) Chem Biol , vol.11 , pp. 1513-1521
    • Li, J.1    Zhu, M.2    Rajamani, S.3    Uversky, V.N.4    Fink, A.L.5
  • 62
    • 52649175462 scopus 로고    scopus 로고
    • Rifampicin reduces alpha-synuclein in a transgenic mouse model of multiple system atrophy
    • Ubhi K., Rockenstein E., Mante M., et al. Rifampicin reduces alpha-synuclein in a transgenic mouse model of multiple system atrophy. Neuroreport 19 (2008) 1271-1276
    • (2008) Neuroreport , vol.19 , pp. 1271-1276
    • Ubhi, K.1    Rockenstein, E.2    Mante, M.3
  • 64
    • 68549125132 scopus 로고    scopus 로고
    • Striatal transplantation for multiple system atrophy: are grafts affected by alpha-synucleinopathy?
    • Stefanova N., Hainzer M., Stemberger S., et al. Striatal transplantation for multiple system atrophy: are grafts affected by alpha-synucleinopathy?. Exp Neurol 219 (2009) 368-371
    • (2009) Exp Neurol , vol.219 , pp. 368-371
    • Stefanova, N.1    Hainzer, M.2    Stemberger, S.3
  • 65
    • 42349097728 scopus 로고    scopus 로고
    • Autologous mesenchymal stem cell therapy delays the progression of neurological deficits in patients with multiple system atrophy
    • Lee P.H., Kim J.W., Bang O.Y., et al. Autologous mesenchymal stem cell therapy delays the progression of neurological deficits in patients with multiple system atrophy. Clin Pharmacol Ther 83 (2008) 723-730
    • (2008) Clin Pharmacol Ther , vol.83 , pp. 723-730
    • Lee, P.H.1    Kim, J.W.2    Bang, O.Y.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.