Mitochondrial inhibitor 3-nitroproprionic acid enhances oxidative modification of alpha-synuclein in a transgenic mouse model of multiple system atrophy

Journal of Neuroscience Research

Volumn 87, Issue 12, 2009, Pages 2728-2739

  Ubhi, Kiren ^a   Phil, Hyu Lee ^b   Adame, Anthony ^a   Inglis, Chandra ^a   Mante, Michael ^a   Rockenstein, Edward ^a   Stefanova, Nadia ^c   Wenning, Gregor K ^c   Masliah, Eliezer ^a,d  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b Yonsei University College of Medicine   (South Korea)

^c INNSBRUCK MEDICAL UNIVERSITY   (Austria)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Behavior; Oligodendrocytes; Synucleinopathy

Indexed keywords

3 NITROPROPRIONIC ACID; ALPHA SYNUCLEIN; CASPASE 3; MYELIN BASIC PROTEIN; TOXIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; EXPERIMENTAL MOUSE; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; MOUSE; NERVE CELL; NEUROPATHOLOGY; NITRATION; NONHUMAN; OLIGODENDROGLIA; OXIDATION; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; SHY DRAGER SYNDROME; SOLUBILITY; TRANSGENIC MOUSE;

ALPHA-SYNUCLEIN; ANIMALS; BRAIN; CONVULSANTS; DISEASE MODELS, ANIMAL; MICE; MICE, TRANSGENIC; MITOCHONDRIA; MULTIPLE SYSTEM ATROPHY; MYELIN BASIC PROTEINS; NERVE DEGENERATION; NITRATES; NITRO COMPOUNDS; OXIDATIVE STRESS; PROMOTER REGIONS, GENETIC; PROPIONIC ACIDS;

EID: 70449478417     PISSN: 03604012     EISSN: 10974547     Source Type: Journal    
DOI: 10.1002/jnr.22089     Document Type: Article

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