-
1
-
-
0031715398
-
NACP/alpha-synuclein immunoreactivity in fibrillary components of neuronal and oligodendroglial cytoplasmic inclusions in the pontine nuclei in multiple system atrophy.
-
K Arima K Ueda N Sunohara K Arakawa S Hirai M Nakamura H Tonozuka-Uehara M Kawai 1998 NACP/alpha-synuclein immunoreactivity in fibrillary components of neuronal and oligodendroglial cytoplasmic inclusions in the pontine nuclei in multiple system atrophy. Acta Neuropathol (Berl) 96 439 444
-
(1998)
Acta Neuropathol (Berl)
, vol.96
, pp. 439-444
-
-
Arima, K.1
Ueda, K.2
Sunohara, N.3
Arakawa, K.4
Hirai, S.5
Nakamura, M.6
Tonozuka-Uehara, H.7
Kawai, M.8
-
2
-
-
0034674376
-
Full length alpha-synuclein is present in cerebrospinal fluid from Parkinson's disease and normal subjects.
-
R Borghi R Marchese A Negro L Marinelli G Forloni D Zaccheo G Abbruzzese M Tabaton 2000 Full length alpha-synuclein is present in cerebrospinal fluid from Parkinson's disease and normal subjects. Neurosci Lett 287 65 67
-
(2000)
Neurosci Lett
, vol.287
, pp. 65-67
-
-
Borghi, R.1
Marchese, R.2
Negro, A.3
Marinelli, L.4
Forloni, G.5
Zaccheo, D.6
Abbruzzese, G.7
Tabaton, M.8
-
3
-
-
0031951010
-
Expression of N-methyl-D-aspartate receptor subunit mRNA in the human brain: Mesencephalic dopaminergic neurons.
-
TJ Counihan B Landwehrmeyer DG Standaert CM Kosinski CR Scherzer LP Daggett G Velicelebi AB Young JB Penney 1998 Expression of N-methyl-D-aspartate receptor subunit mRNA in the human brain: mesencephalic dopaminergic neurons. J Comp Neurol 390 91 101
-
(1998)
J Comp Neurol
, vol.390
, pp. 91-101
-
-
Counihan, T.J.1
Landwehrmeyer, B.2
Standaert, D.G.3
Kosinski, C.M.4
Scherzer, C.R.5
Daggett, L.P.6
Velicelebi, G.7
Young, A.B.8
Penney, J.B.9
-
4
-
-
85109083933
-
Alpha-synuclein implicated in Parkinson's disease is present in extracellular biological fluids, including human plasma.
-
OM El-Agnaf SA Salem KE Paleologou LJ Cooper NJ Fullwood MJ Gibson MD Curran JA Court DM Mann S Ikeda MR Cookson J Hardy D Allsop 2003 Alpha-synuclein implicated in Parkinson's disease is present in extracellular biological fluids, including human plasma. Faseb J 17 1945 1947
-
(2003)
Faseb J
, vol.17
, pp. 1945-1947
-
-
El-Agnaf, O.M.1
Salem, S.A.2
Paleologou, K.E.3
Cooper, L.J.4
Fullwood, N.J.5
Gibson, M.J.6
Curran, M.D.7
Court, J.A.8
Mann, D.M.9
Ikeda, S.10
Cookson, M.R.11
Hardy, J.12
Allsop, D.13
-
5
-
-
10744227740
-
Comparison of kindreds with parkinsonism and alpha-synuclein genomic multiplications.
-
M Farrer J Kachergus L Forno S Lincoln DS Wang M Hulihan D Maraganore K Gwinn-Hardy Z Wszolek D Dickson JW Langston 2004 Comparison of kindreds with parkinsonism and alpha-synuclein genomic multiplications. Ann Neurol 55 174 179
-
(2004)
Ann Neurol
, vol.55
, pp. 174-179
-
-
Farrer, M.1
Kachergus, J.2
Forno, L.3
Lincoln, S.4
Wang, D.S.5
Hulihan, M.6
Maraganore, D.7
Gwinn-Hardy, K.8
Wszolek, Z.9
Dickson, D.10
Langston, J.W.11
-
6
-
-
0036174010
-
Alpha-Synuclein is phosphorylated in synucleinopathy lesions.
-
H Fujiwara M Hasegawa N Dohmae A Kawashima E Masliah MS Goldberg J Shen K Takio T Iwatsubo 2002 alpha-Synuclein is phosphorylated in synucleinopathy lesions. Nat Cell Biol 4 160 164
-
(2002)
Nat Cell Biol
, vol.4
, pp. 160-164
-
-
Fujiwara, H.1
Hasegawa, M.2
Dohmae, N.3
Kawashima, A.4
Masliah, E.5
Goldberg, M.S.6
Shen, J.7
Takio, K.8
Iwatsubo, T.9
-
7
-
-
0033081705
-
Consensus statement on the diagnosis of multiple system atrophy.
-
S Gilman PA Low N Quinn A Albanese Y Ben-Shlomo CJ Fowler H Kaufmann T Klockgether AE Lang PL Lantos I Litvan CJ Mathias E Oliver D Robertson I Schatz GK Wenning 1999 Consensus statement on the diagnosis of multiple system atrophy. J Neurol Sci 163 94 98
-
(1999)
J Neurol Sci
, vol.163
, pp. 94-98
-
-
Gilman, S.1
Low, P.A.2
Quinn, N.3
Albanese, A.4
Ben-Shlomo, Y.5
Fowler, C.J.6
Kaufmann, H.7
Klockgether, T.8
Lang, A.E.9
Lantos, P.L.10
Litvan, I.11
Mathias, C.J.12
Oliver, E.13
Robertson, D.14
Schatz, I.15
Wenning, G.K.16
-
8
-
-
0034069848
-
Distinctive neuropathology revealed by alpha-synuclein antibodies in hereditary parkinsonism and dementia linked to chromosome 4p.
-
K Gwinn-Hardy ND Mehta M Farrer D Maraganore M Muenter SH Yen J Hardy DW Dickson 2000 Distinctive neuropathology revealed by alpha-synuclein antibodies in hereditary parkinsonism and dementia linked to chromosome 4p. Acta Neuropathol (Berl) 99 663 672
-
(2000)
Acta Neuropathol (Berl)
, vol.99
, pp. 663-672
-
-
Gwinn-Hardy, K.1
Mehta, N.D.2
Farrer, M.3
Maraganore, D.4
Muenter, M.5
Yen, S.H.6
Hardy, J.7
Dickson, D.W.8
-
11
-
-
0028985267
-
The precursor protein of non-A beta component of Alzheimer's disease amyloid is a presynaptic protein of the central nervous system.
-
A Iwai E Masliah M Yoshimoto N Ge L Flanagan HA de Silva A Kittel T Saitoh 1995 The precursor protein of non-A beta component of Alzheimer's disease amyloid is a presynaptic protein of the central nervous system. Neuron 14 467 475
-
(1995)
Neuron
, vol.14
, pp. 467-475
-
-
Iwai, A.1
Masliah, E.2
Yoshimoto, M.3
Ge, N.4
Flanagan, L.5
De Silva, H.A.6
Kittel, A.7
Saitoh, T.8
-
12
-
-
26444610170
-
Grading of neuropathology in multiple system atrophy: Proposal for a novel scale.
-
[Suppl 12]
-
KA Jellinger K Seppi GK Wenning 2005 Grading of neuropathology in multiple system atrophy: proposal for a novel scale. Mov Disord 20 [Suppl 12] S29 S36
-
(2005)
Mov Disord
, vol.20
-
-
Jellinger, K.A.1
Seppi, K.2
Wenning, G.K.3
-
13
-
-
0036304315
-
Hyperphosphorylation and insolubility of alpha-synuclein in transgenic mouse oligodendrocytes.
-
PJ Kahle M Neumann L Ozmen V Muller H Jacobsen W Spooren B Fuss B Mallon WB Macklin H Fujiwara M Hasegawa T Iwatsubo HA Kretzschmar C Haass 2002 Hyperphosphorylation and insolubility of alpha-synuclein in transgenic mouse oligodendrocytes. EMBO Rep 3 583 588
-
(2002)
EMBO Rep
, vol.3
, pp. 583-588
-
-
Kahle, P.J.1
Neumann, M.2
Ozmen, L.3
Muller, V.4
Jacobsen, H.5
Spooren, W.6
Fuss, B.7
Mallon, B.8
MacKlin, W.B.9
Fujiwara, H.10
Hasegawa, M.11
Iwatsubo, T.12
Kretzschmar, H.A.13
Haass, C.14
-
15
-
-
0031774904
-
The definition of multiple system atrophy: A review of recent developments.
-
PL Lantos 1998 The definition of multiple system atrophy: a review of recent developments. J Neuropathol Exp Neurol 57 1099 1111
-
(1998)
J Neuropathol Exp Neurol
, vol.57
, pp. 1099-1111
-
-
Lantos, P.L.1
-
16
-
-
0023722437
-
Synuclein: A neuron-specific protein localized to the nucleus and presynaptic nerve terminal.
-
L Maroteaux JT Campanelli RH Scheller 1988 Synuclein: a neuron-specific protein localized to the nucleus and presynaptic nerve terminal. J Neurosci 8 2804 2815
-
(1988)
J Neurosci
, vol.8
, pp. 2804-2815
-
-
Maroteaux, L.1
Campanelli, J.T.2
Scheller, R.H.3
-
17
-
-
27744484059
-
Glial cell inclusions and the pathogenesis of neurodegenerative diseases.
-
DW Miller MR Cookson DW Dickson 2004a Glial cell inclusions and the pathogenesis of neurodegenerative diseases. Neuron Glia Biol 1 13 21
-
(2004)
Neuron Glia Biol
, vol.1
, pp. 13-21
-
-
Miller, D.W.1
Cookson, M.R.2
Dickson, D.W.3
-
19
-
-
0036315240
-
Demonstration of alpha-synuclein immunoreactivity in neuronal and glial cytoplasm in normal human brain tissue using proteinase K and formic acid pretreatment.
-
F Mori K Tanji M Yoshimoto H Takahashi K Wakabayashi 2002 Demonstration of alpha-synuclein immunoreactivity in neuronal and glial cytoplasm in normal human brain tissue using proteinase K and formic acid pretreatment. Exp Neurol 176 98 104
-
(2002)
Exp Neurol
, vol.176
, pp. 98-104
-
-
Mori, F.1
Tanji, K.2
Yoshimoto, M.3
Takahashi, H.4
Wakabayashi, K.5
-
20
-
-
0031842931
-
Cyclin-dependent kinase 5 and mitogen-activated protein kinase in glial cytoplasmic inclusions in multiple system atrophy.
-
S Nakamura Y Kawamoto S Nakano I Akiguchi J Kimura 1998 Cyclin-dependent kinase 5 and mitogen-activated protein kinase in glial cytoplasmic inclusions in multiple system atrophy. J Neuropathol Exp Neurol 57 690 698
-
(1998)
J Neuropathol Exp Neurol
, vol.57
, pp. 690-698
-
-
Nakamura, S.1
Kawamoto, Y.2
Nakano, S.3
Akiguchi, I.4
Kimura, J.5
-
21
-
-
0034091659
-
Expression of the endocytosis regulatory proteins Rab5 and Rabaptin-5 in glial cytoplasmic inclusions from brains with multiple system atrophy.
-
S Nakamura Y Kawamoto S Nakano I Akiguchi 2000 Expression of the endocytosis regulatory proteins Rab5 and Rabaptin-5 in glial cytoplasmic inclusions from brains with multiple system atrophy. Clin Neuropathol 19 51 56
-
(2000)
Clin Neuropathol
, vol.19
, pp. 51-56
-
-
Nakamura, S.1
Kawamoto, Y.2
Nakano, S.3
Akiguchi, I.4
-
22
-
-
0034890258
-
Analysis of the expression level of alpha-synuclein mRNA using postmortem brain samples from pathologically confirmed cases of multiple system atrophy.
-
T Ozawa K Okuizumi T Ikeuchi K Wakabayashi H Takahashi S Tsuji 2001 Analysis of the expression level of alpha-synuclein mRNA using postmortem brain samples from pathologically confirmed cases of multiple system atrophy. Acta Neuropathol (Berl) 102 188 190
-
(2001)
Acta Neuropathol (Berl)
, vol.102
, pp. 188-190
-
-
Ozawa, T.1
Okuizumi, K.2
Ikeuchi, T.3
Wakabayashi, K.4
Takahashi, H.5
Tsuji, S.6
-
23
-
-
0024843373
-
Glial cytoplasmic inclusions in the CNS of patients with multiple system atrophy (striatonigral degeneration, olivopontocerebellar atrophy and Shy-Drager syndrome).
-
MI Papp JE Kahn PL Lantos 1989 Glial cytoplasmic inclusions in the CNS of patients with multiple system atrophy (striatonigral degeneration, olivopontocerebellar atrophy and Shy-Drager syndrome). J Neurol Sci 94 79 100
-
(1989)
J Neurol Sci
, vol.94
, pp. 79-100
-
-
Papp, M.I.1
Kahn, J.E.2
Lantos, P.L.3
-
24
-
-
0035108490
-
Co-localization of alpha-synuclein and phosphorylated tau in neuronal and glial cytoplasmic inclusions in a patient with multiple system atrophy of long duration.
-
YS Piao S Hayashi M Hasegawa K Wakabayashi M Yamada M Yoshimoto A Ishikawa T Iwatsubo H Takahashi 2001 Co-localization of alpha-synuclein and phosphorylated tau in neuronal and glial cytoplasmic inclusions in a patient with multiple system atrophy of long duration. Acta Neuropathol (Berl) 101 285 293
-
(2001)
Acta Neuropathol (Berl)
, vol.101
, pp. 285-293
-
-
Piao, Y.S.1
Hayashi, S.2
Hasegawa, M.3
Wakabayashi, K.4
Yamada, M.5
Yoshimoto, M.6
Ishikawa, A.7
Iwatsubo, T.8
Takahashi, H.9
-
26
-
-
0242300619
-
Alpha-Synuclein locus triplication causes Parkinson's disease.
-
AB Singleton M Farrer J Johnson A Singleton S Hague J Kachergus M Hulihan T Peuralinna A Dutra R Nussbaum S Lincoln A Crawley M Hanson D Maraganore C Adler MR Cookson M Muenter M Baptista D Miller J Blancato J Hardy K Gwinn-Hardy 2003 alpha-Synuclein locus triplication causes Parkinson's disease. Science 302 841
-
(2003)
Science
, vol.302
, pp. 841
-
-
Singleton, A.B.1
Farrer, M.2
Johnson, J.3
Singleton, A.4
Hague, S.5
Kachergus, J.6
Hulihan, M.7
Peuralinna, T.8
Dutra, A.9
Nussbaum, R.10
Lincoln, S.11
Crawley, A.12
Hanson, M.13
Maraganore, D.14
Adler, C.15
Cookson, M.R.16
Muenter, M.17
Baptista, M.18
Miller, D.19
Blancato, J.20
Hardy, J.21
Gwinn-Hardy, K.22
more..
-
27
-
-
0033961490
-
Expression of alpha-synuclein, parkin, and ubiquitin carboxy-terminal hydrolase L1 mRNA in human brain: Genes associated with familial Parkinson's disease.
-
SM Solano DW Miller SJ Augood AB Young JB Penney Jr 2000 Expression of alpha-synuclein, parkin, and ubiquitin carboxy-terminal hydrolase L1 mRNA in human brain: genes associated with familial Parkinson's disease. Ann Neurol 47 201 210
-
(2000)
Ann Neurol
, vol.47
, pp. 201-210
-
-
Solano, S.M.1
Miller, D.W.2
Augood, S.J.3
Young, A.B.4
Penney Jr., J.B.5
-
28
-
-
0032584686
-
Filamentous alpha-synuclein inclusions link multiple system atrophy with Parkinson's disease and dementia with Lewy bodies.
-
MG Spillantini RA Crowther R Jakes NJ Cairns PL Lantos M Goedert 1998 Filamentous alpha-synuclein inclusions link multiple system atrophy with Parkinson's disease and dementia with Lewy bodies. Neurosci Lett 251 205 208
-
(1998)
Neurosci Lett
, vol.251
, pp. 205-208
-
-
Spillantini, M.G.1
Crowther, R.A.2
Jakes, R.3
Cairns, N.J.4
Lantos, P.L.5
Goedert, M.6
-
29
-
-
0035920226
-
Induction of neuronal cell death by Rab5A-dependent endocytosis of alpha-synuclein.
-
JY Sung J Kim SR Paik JH Park YS Ahn KC Chung 2001 Induction of neuronal cell death by Rab5A-dependent endocytosis of alpha-synuclein. J Biol Chem 276 27441 27448
-
(2001)
J Biol Chem
, vol.276
, pp. 27441-27448
-
-
Sung, J.Y.1
Kim, J.2
Paik, S.R.3
Park, J.H.4
Ahn, Y.S.5
Chung, K.C.6
-
30
-
-
0032546895
-
Alpha-synuclein immunoreactivity in glial cytoplasmic inclusions in multiple system atrophy.
-
K Wakabayashi M Yoshimoto S Tsuji H Takahashi 1998 Alpha-synuclein immunoreactivity in glial cytoplasmic inclusions in multiple system atrophy. Neurosci Lett 249 180 182
-
(1998)
Neurosci Lett
, vol.249
, pp. 180-182
-
-
Wakabayashi, K.1
Yoshimoto, M.2
Tsuji, S.3
Takahashi, H.4
-
32
-
-
15444376598
-
Mouse model of multiple system atrophy alpha-synuclein expression in oligodendrocytes causes glial and neuronal degeneration.
-
I Yazawa BI Giasson R Sasaki B Zhang S Joyce K Uryu JQ Trojanowski VM Lee 2005 Mouse model of multiple system atrophy alpha-synuclein expression in oligodendrocytes causes glial and neuronal degeneration. Neuron 45 847 859
-
(2005)
Neuron
, vol.45
, pp. 847-859
-
-
Yazawa, I.1
Giasson, B.I.2
Sasaki, R.3
Zhang, B.4
Joyce, S.5
Uryu, K.6
Trojanowski, J.Q.7
Lee, V.M.8
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