Identification of hemopexin as an anti-inflammatory factor that inhibits synergy of hemoglobin with HMGB1 in sterile and infectious inflammation

Journal of Immunology

Volumn 189, Issue 4, 2012, Pages 2017-2022

  Lin, Tian ^a   Sammy, Fatima ^a   Yang, Huan ^b   Thundivalappil, Sujatha ^a   Hellman, Judith ^c   Tracey, Kevin J ^b   Warren, H Shaw ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADVANCED GLYCATION END PRODUCT RECEPTOR; HEMOGLOBIN; HEMOPEXIN; HIGH MOBILITY GROUP B1 PROTEIN; INTERLEUKIN 6; MYELOID DIFFERENTIATION FACTOR 88; PROTEIN KINASE SYK; REACTIVE OXYGEN METABOLITE; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR ADAPTOR MOLECULE 1; TUMOR NECROSIS FACTOR;

ANIMAL CELL; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; ENZYME ACTIVATION; HUMAN; HUMAN CELL; IMMUNOMODULATION; INFLAMMATION; MACROPHAGE ACTIVATION; MOUSE; NONHUMAN; NORMAL HUMAN; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; UPREGULATION;

ANIMALS; CYTOKINES; HEMOGLOBINS; HEMOPEXIN; HMGB1 PROTEIN; HUMANS; INFECTION; INFLAMMATION; MACROPHAGE ACTIVATION; MACROPHAGES; MICE; MICE, INBRED C57BL;

EID: 84864809340     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1103623     Document Type: Article

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