Delineation of lipopolysaccharide (LPS)-binding sites on hemoglobin: From in silico predictions to biophysical characterization

Journal of Biological Chemistry

Volumn 286, Issue 43, 2011, Pages 37793-37803

  Bahl, Neha ^a   Du, Ruijuan ^b   Winarsih, Imelda ^b   Ho, Bow ^b   Tucker Kellogg, Lisa ^a   Tidor, Bruce ^a   Ding, Jeak Ling ^a,b  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^b NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

BIOPHYSICAL CHARACTERIZATION; CELL-FREE; COMPUTATIONAL PREDICTIONS; DISPLACEMENT ASSAY; ENDOTOXICITY; FLUORESCENT PROBES; FRONTLINE; GRAM-NEGATIVE BACTERIA; HIGH AFFINITY; HOT SPOT; IMMUNE DEFENSE; IN-SILICO; IN-VITRO; LIPID A; LIPOPOLYSACCHARIDES; NANOMOLAR RANGE; PROTEIN-LIGAND INTERACTIONS; REDOX ACTIVITY; SEQUENCE COMPARISONS; SITE DIRECTED MUTAGENESIS; STRUCTURAL CHANGE; STRUCTURE-BASED; SURFACE PLASMONS;

BACTERIA; FLOW CYTOMETRY; FORECASTING; FREE RADICALS; HEMOGLOBIN; PEPTIDES; PLASMONS; REDOX REACTIONS; SCANNING ELECTRON MICROSCOPY; SURFACE PLASMON RESONANCE;

BINDING SITES;

HEMOGLOBIN A; HEMOGLOBIN BETA CHAIN; LIPID A; LIPOPOLYSACCHARIDE;

ARTICLE; BINDING AFFINITY; BINDING SITE; CARBOHYDRATE ANALYSIS; COMPUTER MODEL; COMPUTER PREDICTION; CONTROLLED STUDY; ESCHERICHIA COLI; HEMOGLOBIN ANALYSIS; IN VITRO STUDY; LIGAND BINDING; MATHEMATICAL COMPUTING; MOLECULAR DOCKING; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CARBOHYDRATE INTERACTION; PROTEIN LIPID INTERACTION; PSEUDOMONAS AERUGINOSA; SEQUENCE HOMOLOGY; SITE DIRECTED MUTAGENESIS;

BINDING SITES; HEMOGLOBINS; HUMANS; LIPOPOLYSACCHARIDES; MODELS, MOLECULAR; PROTEIN BINDING;

NEGIBACTERIA;

EID: 80054799282     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.245472     Document Type: Article

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