High levels of activin a detected in preeclamptic placenta induce trophoblast cell apoptosis by promoting nodal signaling

Journal of Clinical Endocrinology and Metabolism

Volumn 97, Issue 8, 2012, Pages

  Yu, Ling ^a,d   Li, Dong ^a,d   Liao, Qin Ping ^c   Yang, Hui Xia ^c   Cao, Bin ^a,d   Fu, Guodong ^b   Ye, Gang ^b   Bai, Yang ^a,d   Wang, Hao ^a,d   Cui, Nana ^a   Liu, Ming ^a   Li, Yu Xia ^a   Li, Jun ^e   Peng, Chun ^b   Wang, Yan Ling ^a  

^a INSTITUTE OF ZOOLOGY   (China)

^b YORK UNIVERSITY   (Canada)

^c PEKING UNIVERSITY FIRST HOSPITAL   (China)

^d UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

^e CHINA MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVIN A; ACTIVIN RECEPTOR; ACTIVIN RECEPTOR LIKE KINASE 4; ACTIVIN RECEPTOR LIKE KINASE 7; MESSENGER RNA; PROTEIN NODAL; UNCLASSIFIED DRUG;

ADULT; APOPTOSIS; ARTICLE; CHINESE; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOTROPHOBLAST; DISEASE SEVERITY; FEMALE; GENE EXPRESSION REGULATION; GENE SILENCING; HUMAN; HUMAN CELL; HUMAN TISSUE; INTRACELLULAR SIGNALING; MOLECULAR PATHOLOGY; PATHOGENESIS; PLACENTA LOCALIZATION; PREECLAMPSIA; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; UPREGULATION;

ACTIVIN RECEPTORS, TYPE I; ACTIVINS; ADULT; AMINO ACID SEQUENCE; APOPTOSIS; CASE-CONTROL STUDIES; CELLS, CULTURED; FEMALE; HUMANS; MATRIX METALLOPROTEINASES; MOLECULAR SEQUENCE DATA; PLACENTA; PRE-ECLAMPSIA; PREGNANCY; PROSPECTIVE STUDIES; SIGNAL TRANSDUCTION; TROPHOBLASTS;

EID: 84864806632     PISSN: 0021972X     EISSN: 19457197     Source Type: Journal    
DOI: 10.1210/jc.2011-2729     Document Type: Article

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