The secretion and effect of inhibin A, activin A and follistatin on first-trimester trophoblasts in vitro

European Journal of Endocrinology

Volumn 152, Issue 6, 2005, Pages 909-916

  Bearfield, C ^c   Jauniaux, E ^c   Groome, N ^a   Sargent, I L ^b   Muttukrishna, S ^c  

^a OXFORD BROOKES UNIVERSITY   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVIN A; EPIDERMAL GROWTH FACTOR; FOLLISTATIN; GELATIN; INHIBIN A; INTERLEUKIN 1BETA;

ARTICLE; CELL CULTURE; CELL INVASION; CELL ISOLATION; CHORION VILLUS; CONTROLLED STUDY; CYTOTROPHOBLAST; EMBRYO; EMBRYO DEVELOPMENT; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FIRST TRIMESTER PREGNANCY; GESTATIONAL AGE; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; PLACENTA; PRIORITY JOURNAL; PROTEIN SECRETION; RADIOASSAY; STATISTICAL SIGNIFICANCE;

ACTIVINS; CELL ADHESION; CHORIONIC GONADOTROPIN; EPIDERMAL GROWTH FACTOR; FEMALE; FOLLISTATIN; HUMANS; INHIBIN-BETA SUBUNITS; INHIBINS; INTERLEUKIN-1; PLACENTATION; PREGNANCY; PREGNANCY TRIMESTER, FIRST; TROPHOBLASTS;

EID: 21344461474     PISSN: 08044643     EISSN: None     Source Type: Journal    
DOI: 10.1530/eje.1.01928     Document Type: Article

References (37)

1. Morrish D. Functional regulation of human trophoblast differentiation. Journal of Reproductive Immunology 1998 39 179-195.
2. Graham CH & Lala PK. Mechanism of control of trophoblast invasion in situ. Journal of Cell Physiology 1991 148 228-234.
3. Graham CH & Lala PK. Mechanism of placental invasion of the uterus and their control. Biochemistry and Cell Biology 1992 70 867-874.
4. Petraglia F, Garuti GC, Calza L, Roberts V, Giardino L, Genazzani AR, Vale W & Meunier H. Inhibin subunits in human placenta: localization and messenger ribonucleic acid levels during pregnancy. American Journal of Obstetrics and Gynecology 1991 165 750-758.
5. Peng C, Ohno T, Koh LY, Chen VT & Leung PC. Human ovary and placenta express messenger RNA for multiple activin receptors. Life Science 1999 64 983-994.
6. Muttukrishna S, George L, Fowler PA, Groome NP & Knight PG. Measurement of serum concentrations of inhibin-A (alpha-beta A dimer) during human pregnancy. Clinical Endocrinology 1995 42 391-397.
7. Muttukrishna S, Fowler PA, George L, Groome NP & Knight PG. Changes in peripheral serum levels of 'total' activin A during the human menstrual cycle and pregnancy. Journal of Clinical Endocrinology and Metabolism 1996 81 3328-3334.
8. Fowler PA, Evans LW, Groome NP, Templeton A & Knight PG. A longitudinal study of maternal serum inhibin-A, inhibin-B, activin-A, activin-AB, pro-alphaC and follistatin during pregnancy. Human Reproduction 1998 13 3530-3536.
9. Muttukrishna S, Knight PG, Groome NP, Redman CWG & Ledger WL. Inhibin A and activin A: new endocrine markers for pre-eclampsia? Lancet 1997 349 1285-1288.
10. Muttukrishna S, North RA, Morris J, Schellenberg JC, Taylor RS, Asselin J, Ledger W, Groome N & Redman CW. Serum inhibin and activin A are elevated prior to the onset of pre-eclampsia. Human Reproduction 2000 15 1640-1645.
11. Burton GJ & Jauniaux E. Pathophysiology of histological changes in early pregnancy loss. Placenta 2005 3 114-123.
12. Caniggia I, Lye SJ & Cross JC. Activin is a local regulator of human cytotrophoblast cell differentiation. Endocrinology 1997 138 3976-3986.
13. Mohan A, Asselin J, Sargent IL, Groome NP & Muttukrishna S. Effect of cytokines and growth factors on the secretion of inhibin A, activin A and follistatin by term placental villous trophoblasts in culture. European Journal of Endocrinology 2001 145 505-511.
14. Sacks GP, Clover LM, Bainbridge DR, Redman CW & Sargent IL. Flow cytometric measurement of intracellular Th1 and Th2 cytokine production by human villous and extravillous cytotrophoblast. Placenta 2001 22 550-559.
15. Guibourdenche J, Frendo JL, Pidoux G, Bertin G, Luton D, Muller F, Porquet D & Evain-Brion D. Expression of pregnancy associated plasma protein A (PAPP-A) during human villous trophoblasts differentiation in vitro. Placenta 2003 24 532-539.
16. Fisher SJ & Damsky CH. Human cytotrophoblast invasion. Seminars in Cell Biology 1993 4 183-188.
17. Bass KE, Morrish D, Roth I, Bhardwaj D, Taylor R & Zhou Y. Human cytotrophoblast invasion is up regulated by epidermal growth factor: evidence that paracrine factors modify this process. Developmental Biology 1994 164 550-561.
18. Librach CL, Feigenbaum SL, Bass KE, Cui TY, Verastas N, Sadovsky Y, Quigley JP, French DL & Fisher SL. Interleukin-1 beta regulates human cytotrophoblast metalloproteinase activity and invasion in vitro. Journal of Biological Chemistry 1994 269 17125-17131.
19. Damsky CH, Librach C, Lim KH, Fitzgerald ML, McMaster MT, Janatpour M, Zhou Y, Logan SK & Fisher SJ. Integrin switching regulates normal trophoblast invasion. Development 1994 120 3657-3666.
20. Genbacev O, Joslin R, Damsky CH, Polliotti BM & Fisher SJ. Hypoxia alters early gestation human cytotrophoblast differentiation/invasion in vitro and models the placental defects that occur in preeclampsia. Journal of Clinical Investigation 1996 97 540-550.
21. Shimonovitz S, Hurwitz A, Dushnik M, Anteby E, Geva-Eldar T & Yagel S. Developmental regulation of the expression of 72 and 92kd type IV collagenases in human trophoblast: a possible mechanism for control of trophoblast invasion. American Journal of Obstetrics and Gynaecology 1994 171 832-838.
22. Graham CH, Connelly I, MacDougall JR, Kerbel RS, Stetler-Stevenson WG & Lala PK. Resistance of malignant trophoblast cells to both the anti-proliferative and anti-invasive effects of transforming growth factor-beta. Experimental Cell Research 1994 214 93-99.
23. Redman CW & Sargent IL. Pre eclampsia, the placenta and the maternal systemic inflammatory response - a review. Placenta 2003 24 Suppl S21-S27.
24. Fisher SJ, Sutherland A, Moss L, Hartman L, Crowley E, Bernfield M, Calarco P & Damsky C. Adhesive interactions of murine and human trophoblast cells. Trophoblast Research 1990 4 115-138.
25. Linton FA, Rodriguez-Linares B, Rashid-Doubell F, Ferguson DJ & Redman CW. Caveolae and caveolin-1 in human term villous trophoblast. Placenta 2003 24 745-757.
26. Muttukrishna S, Groome NP & Ledger WL. Gonadotrophic control of secretion of dimeric inhibins and activin A by human granulosa-luteal cells in vitro. Journal of Assisted Reproduction and Genetics 1997 14 566-574.
27. Evans LW, Muttukrishna S & Groome NP. Development, validation and application of an ultra sensitive two-site enzyme immunoassay for human follistatin. Journal of Endocrinology 1998 156 275-282.
28. Irving JA & Lala PK. Functional role of cell surface integrins on human trophoblast cell migration: regulation by TGF-β, IGF-II and IGFBP-I. Experimental and Cell Research 1995 217 419-427.
29. Athanassiades A & Lala PK. Role of placenta growth factor (PIGF) in human extravillous trophoblast proliferation, migration and invasiveness. Placenta 1998 19 465-473.
30. Athanassiades A, Hamilton GS & Lala PK. Vascular endothelial growth factor stimulates proliferation but not migration or invasiveness in human extravillous trophoblast. Biology of Reproduction 1998 59 643-654.
31. Damsky CH, Fitzgerald ML & Fisher SJ. Distribution patterns of extracellular matrix components and adhesion receptors are intricately modulated during first trimester cytotrophoblast differentiation along the invasive pathway in vivo. Journal of Clinical Investigation 1992 89 210-222.
32. Zhou Y, Damsky CH, Chiu K, Roberts JH & Fisher SJ. Pre eclampsia is associated with abnormal expression of adhesion molecules by invasive cytotrophoblasts. Journal of Clinical Investigation 1993 91 950-960.
33. Chen VT, Peng C & Leung PC. Activin A up-regulates type I activin receptor mRNA levels in human immortilised extravillous trophoblast cells. Reproductive Biology and Endocrinology 2003 1 1-9.
34. Qu J, Ying S-Y & Thomas K. Inhibin production and secretion in human placental cells cultured in vitro. Obstetrics and Gynaecology 1992 79 705-712.
35. Mather JP, Woodruff TK & Krummen LA. Paracrine regulation of reproductive function by inhibin and activin. Proceedings of the Society for Experimental Biology and Medicine 1992 201 1-15.
36. Keelan J, Song Y & France JT. Comparative regulation of inhibin, activin and human chorionic gonadotropin production by placental trophoblast cells in culture. Placenta 1994 15 803-818.
37. Kozian DH, Ziche M & Augustin HG. The activin-binding protein follistatin regulates autocrine endothelial cell activity and induces angiogenesis. Laboratory Investigation 1997 76 267-276.