Sphingosine kinase-1 is a downstream regulator of imatinib-induced apoptosis in chronic myeloid leukemia cells

Leukemia

Volumn 22, Issue 5, 2008, Pages 971-979

  Bonhoure, E ^a,b,c   Lauret, A ^b,c   Barnes, D J ^d   Martin, C ^a,c   Malavaud, B ^a,c   Kohama, T ^e   Melo, J V ^d   Cuvillier, O ^a,b,c  

^a INSTITUT DE PHARMACOLOGIE ET DE BIOLOGIE STRUCTURALE   (France)

^b INSERM   (France)

^c UNIVERSITÉ DE TOULOUSE   (France)

^d HAMMERSMITH HOSPITAL   (United Kingdom)

^e DAIICHI SANKYO CO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BCR ABL PROTEIN; BIM PROTEIN; CASPASE 3; CERAMIDE; CYTARABINE; CYTOCHROME C; ENZYME INHIBITOR; F 12509A; IMATINIB; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN FARNESYLTRANSFERASE INHIBITOR; PROTEIN MCL 1; RAS PROTEIN; SECOND MITOCHONDRIAL ACTIVATOR OF CASPASE; SMALL INTERFERING RNA; SPHINGOLIPID; SPHINGOSINE 1 PHOSPHATE; SPHINGOSINE KINASE 1; SPHINGOSINE KINASE INIBITOR; UO 126;

APOPTOSIS; ARTICLE; CELL KILLING; CHRONIC MYELOID LEUKEMIA; CONTROLLED STUDY; DRUG SENSITIVITY; ENZYME ACTIVATION; ENZYME INHIBITION; HUMAN; HUMAN CELL; IN VITRO STUDY; LEUKEMIA CELL; LIPID METABOLISM; MITOCHONDRION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SECRETION; SIGNAL TRANSDUCTION;

EID: 43749123266     PISSN: 08876924     EISSN: 14765551     Source Type: Journal    
DOI: 10.1038/leu.2008.95     Document Type: Article

References (41)