Involvement of sphingosine-1-phosphate and S1P1 in angiogenesis: Analyses using a new S1P1 antagonist of non-sphingosine-1-phosphate analog

Biochemical Pharmacology

Volumn 77, Issue 6, 2009, Pages 1011-1020

  Yonesu, Kiyoaki ^a   Kawase, Yumi ^a   Inoue, Tatsuya ^a   Takagi, Nana ^a   Tsuchida, Jun ^a   Takuwa, Yoh ^b   Kumakura, Seiichiro ^a   Nara, Futoshi ^a  

^a DAIICHI SANKYO CO   (Japan)

^b KANAZAWA UNIVERSITY GRADUATE SCHOOL OF MEDICAL SCIENCE   (Japan)

Author keywords

Angiogenesis inhibitor; Anti arthritis; Endothelial differentiation gene 1 (Edg 1 S1P1); Sphingosine 1 phosphate (Sph 1 P); Tube formation

Indexed keywords

ANGIOGENESIS INHIBITOR; CHEMICAL LEAD 2; COLLAGEN TYPE 2; SPHINGOSINE 1 PHOSPHATE; SPHINGOSINE 1 PHOSPHATE 1; SPHINGOSINE 1 PHOSPHATE 1 ANTAGONIST; UNCLASSIFIED DRUG; VASCULOTROPIN;

ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIANGIOGENIC ACTIVITY; ARTICLE; CELL MIGRATION; CONTROLLED STUDY; DIABETIC RETINOPATHY; DRUG ACTIVITY; DRUG BLOOD LEVEL; DRUG INHIBITION; FOOT EDEMA; HUMAN; HUMAN CELL; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RHEUMATOID ARTHRITIS;

ANGIOGENESIS INHIBITORS; ANIMALS; CELL MOVEMENT; CELLS, CULTURED; CHO CELLS; COCULTURE TECHNIQUES; CRICETINAE; CRICETULUS; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; LYSOPHOSPHOLIPIDS; MALE; MICE; MICE, INBRED BALB C; NEOVASCULARIZATION, PATHOLOGIC; NEOVASCULARIZATION, PHYSIOLOGIC; RABBITS; RECEPTORS, LYSOSPHINGOLIPID; SPHINGOSINE;

EID: 60649101023     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2008.12.007     Document Type: Article

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