메뉴 건너뛰기




Volumn 40, Issue 4, 2009, Pages 276-284

Intracellular Cytokine Production in ANCA-associated Vasculitis: Low Levels of Interleukin-10 in Remission Are Associated with a Higher Relapse Rate in the Long-term Follow-up

Author keywords

Anti neutrophil cytoplasmic autoantibodies (ANCA); Interleukin 10; Intracellular cytokines; Relapse; Vasculitis

Indexed keywords

AZATHIOPRINE; CORTICOSTEROID; CYCLOPHOSPHAMIDE; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 2; INTERLEUKIN 4; METHYLPREDNISOLONE; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; PREDNISOLONE; TUMOR NECROSIS FACTOR ALPHA;

EID: 67650073210     PISSN: 01884409     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.arcmed.2009.04.001     Document Type: Article
Times cited : (21)

References (45)
  • 1
    • 0028158243 scopus 로고
    • Nomenclature of systemic vasculitides-proposal of an international consensus conference
    • Jennette J.C., Falk R.J., Andrassy K., et al. Nomenclature of systemic vasculitides-proposal of an international consensus conference. Arthritis Rheum 37 (1994) 187-192
    • (1994) Arthritis Rheum , vol.37 , pp. 187-192
    • Jennette, J.C.1    Falk, R.J.2    Andrassy, K.3
  • 2
    • 0030725347 scopus 로고    scopus 로고
    • Small vessel vasculitis
    • Jennette J.C., and Falk R.J. Small vessel vasculitis. N Engl J Med 337 (1997) 1512-1523
    • (1997) N Engl J Med , vol.337 , pp. 1512-1523
    • Jennette, J.C.1    Falk, R.J.2
  • 3
    • 0032015329 scopus 로고    scopus 로고
    • Diagnostic predictive value of ANCA serology
    • Jennette J.C., Wilkman A.S., and Falk R.J. Diagnostic predictive value of ANCA serology. Kidney Int 53 (1998) 796-798
    • (1998) Kidney Int , vol.53 , pp. 796-798
    • Jennette, J.C.1    Wilkman, A.S.2    Falk, R.J.3
  • 4
    • 0037338664 scopus 로고    scopus 로고
    • Serial ANCA titers: useful tool for prevention of relapses in ANCA-associated vasculitis
    • Han W.K., Choi H.K., Roth R.M., McCluskey R.T., and Niles J.L. Serial ANCA titers: useful tool for prevention of relapses in ANCA-associated vasculitis. Kidney Int 63 (2003) 1079-1085
    • (2003) Kidney Int , vol.63 , pp. 1079-1085
    • Han, W.K.1    Choi, H.K.2    Roth, R.M.3    McCluskey, R.T.4    Niles, J.L.5
  • 5
    • 29244461435 scopus 로고    scopus 로고
    • Serial ANCA determinations for monitoring disease activity in patients with ANCA-associated vasculitis: systematic review
    • Birck R., Schmitt W.H., Kaelsch I.A., and van der Woude F.J. Serial ANCA determinations for monitoring disease activity in patients with ANCA-associated vasculitis: systematic review. Am J Kidney Dis 47 (2006) 15-23
    • (2006) Am J Kidney Dis , vol.47 , pp. 15-23
    • Birck, R.1    Schmitt, W.H.2    Kaelsch, I.A.3    van der Woude, F.J.4
  • 6
    • 0023878734 scopus 로고
    • Anti-neutrophil cytoplasmic autoantibodies with specificity for myeloperoxidase in patients with systemic vasculitis and idiopathic necrotizing and crescentic glomerulonephritis
    • Falk R.J., and Jennette J.C. Anti-neutrophil cytoplasmic autoantibodies with specificity for myeloperoxidase in patients with systemic vasculitis and idiopathic necrotizing and crescentic glomerulonephritis. N Engl J Med 318 (1988) 1651-1657
    • (1988) N Engl J Med , vol.318 , pp. 1651-1657
    • Falk, R.J.1    Jennette, J.C.2
  • 7
    • 0025353345 scopus 로고
    • Specificity of anti-neutrophil cytoplasmic autoantibodies for proteinase 3
    • Jennette J.C., and Falk R.J. Specificity of anti-neutrophil cytoplasmic autoantibodies for proteinase 3. Blood 75 (1990) 2263-2264
    • (1990) Blood , vol.75 , pp. 2263-2264
    • Jennette, J.C.1    Falk, R.J.2
  • 8
    • 22144474804 scopus 로고    scopus 로고
    • Long-term outcome of patients with antineutrophil cytoplasmic autoantibody-associated vasculitis with renal involvement
    • Rihova Z., Jancova E., Merta M., et al. Long-term outcome of patients with antineutrophil cytoplasmic autoantibody-associated vasculitis with renal involvement. Kidney Blood Press Res 28 (2005) 144-152
    • (2005) Kidney Blood Press Res , vol.28 , pp. 144-152
    • Rihova, Z.1    Jancova, E.2    Merta, M.3
  • 9
    • 33745609792 scopus 로고    scopus 로고
    • Prediction of relapses in PR3-ANCA-associated vasculitis by assessing responses of ANCA titres to treatment
    • Sanders J.S., Huitma M.G., Kallenberg C.G., and Stegeman C.A. Prediction of relapses in PR3-ANCA-associated vasculitis by assessing responses of ANCA titres to treatment. Rheumatology 45 (2006) 724-729
    • (2006) Rheumatology , vol.45 , pp. 724-729
    • Sanders, J.S.1    Huitma, M.G.2    Kallenberg, C.G.3    Stegeman, C.A.4
  • 10
    • 1842780219 scopus 로고    scopus 로고
    • Positive classic antineutrophil cytoplasmic antibody (C-ANCA) titer at switch to azathioprine therapy associated with relapse in proteinase 3-related vasculitis
    • Slot M.C., Tervaert J.W., Boomsma M.M., and Stegeman C.A. Positive classic antineutrophil cytoplasmic antibody (C-ANCA) titer at switch to azathioprine therapy associated with relapse in proteinase 3-related vasculitis. Arthritis Rheum 51 (2004) 269-273
    • (2004) Arthritis Rheum , vol.51 , pp. 269-273
    • Slot, M.C.1    Tervaert, J.W.2    Boomsma, M.M.3    Stegeman, C.A.4
  • 11
    • 33845746405 scopus 로고    scopus 로고
    • Mechanisms of vasculitis: how pauci-immune is ANCA-associated renal vasculitis?
    • van Paassen P., Cohen Tervaert J.W., and Heeringa P. Mechanisms of vasculitis: how pauci-immune is ANCA-associated renal vasculitis?. Nephron Exp Nephrol 105 (2007) e10-e16
    • (2007) Nephron Exp Nephrol , vol.105
    • van Paassen, P.1    Cohen Tervaert, J.W.2    Heeringa, P.3
  • 12
    • 33646367170 scopus 로고    scopus 로고
    • Anti-neutrophil cytoplasm-associated glomerulonephritis
    • Morgan M.D., Harper L., Williams J., and Savage C. Anti-neutrophil cytoplasm-associated glomerulonephritis. J Am Soc Nephrol 17 (2006) 1224-1234
    • (2006) J Am Soc Nephrol , vol.17 , pp. 1224-1234
    • Morgan, M.D.1    Harper, L.2    Williams, J.3    Savage, C.4
  • 13
    • 33746292135 scopus 로고    scopus 로고
    • Antineutrophil cytoplasmic antibodies
    • Bosch X., Guilabert A., and Font J. Antineutrophil cytoplasmic antibodies. Lancet 368 (2006) 404-4018
    • (2006) Lancet , vol.368 , pp. 404-4018
    • Bosch, X.1    Guilabert, A.2    Font, J.3
  • 14
    • 31044449754 scopus 로고    scopus 로고
    • Pathogenesis of Wegener's granulomatosis: current concepts
    • Sarraf P., and Sneller M.C. Pathogenesis of Wegener's granulomatosis: current concepts. Expert Rev Mol Med 7 (2005) 1-19
    • (2005) Expert Rev Mol Med , vol.7 , pp. 1-19
    • Sarraf, P.1    Sneller, M.C.2
  • 15
    • 0026802170 scopus 로고
    • Elevated serum levels of soluble interleukin-2 receptor in patients with Wegener's granulomatosis. Association with disease activity
    • Schmitt W.H., Heesen C., Csernok E., Rautman A., and Gross W.L. Elevated serum levels of soluble interleukin-2 receptor in patients with Wegener's granulomatosis. Association with disease activity. Arthritis Rheum 35 (1992) 1088-1096
    • (1992) Arthritis Rheum , vol.35 , pp. 1088-1096
    • Schmitt, W.H.1    Heesen, C.2    Csernok, E.3    Rautman, A.4    Gross, W.L.5
  • 18
    • 33745608718 scopus 로고    scopus 로고
    • Persistent T cell activation and clinical correlations in patients with ANCA-associated systemic vasculitis
    • Marinaki S., Kalsch A.I., Grimminger P., et al. Persistent T cell activation and clinical correlations in patients with ANCA-associated systemic vasculitis. Nephrol Dial Transplant 21 (2006) 1825-1832
    • (2006) Nephrol Dial Transplant , vol.21 , pp. 1825-1832
    • Marinaki, S.1    Kalsch, A.I.2    Grimminger, P.3
  • 19
    • 20144388308 scopus 로고    scopus 로고
    • Abnormalities of CD4+ T cell subpopulations in ANCA-associated vasculitis
    • Marinaki S., Neumann I., Kalsch A.I., et al. Abnormalities of CD4+ T cell subpopulations in ANCA-associated vasculitis. Clin Exp Immunol 140 (2005) 181-191
    • (2005) Clin Exp Immunol , vol.140 , pp. 181-191
    • Marinaki, S.1    Neumann, I.2    Kalsch, A.I.3
  • 20
    • 2642680076 scopus 로고    scopus 로고
    • Active Wegener's granulomatosis is associated with HLA-DR+ CD4+ T cells exhibiting an unbalanced Th1-type T cell cytokine pattern: reversal with IL-10
    • Ludviksson B.R., Sneller M.C., Chua K.S., et al. Active Wegener's granulomatosis is associated with HLA-DR+ CD4+ T cells exhibiting an unbalanced Th1-type T cell cytokine pattern: reversal with IL-10. J Immunol 160 (1998) 3602-3609
    • (1998) J Immunol , vol.160 , pp. 3602-3609
    • Ludviksson, B.R.1    Sneller, M.C.2    Chua, K.S.3
  • 21
    • 0036068953 scopus 로고    scopus 로고
    • In vitro cytokine production and proliferation of T cells from patients with anti-proteinase 3- and antimyeloperoxidase-associated vasculitis, in response to proteinase 3 and myeloperoxidase
    • Popa E.R., Franssen C.F., Limburg P.C., Huitema M.G., Kallenberg C.G., and Tervaert J.W. In vitro cytokine production and proliferation of T cells from patients with anti-proteinase 3- and antimyeloperoxidase-associated vasculitis, in response to proteinase 3 and myeloperoxidase. Arthritis Rheum 46 (2002) 1894-1904
    • (2002) Arthritis Rheum , vol.46 , pp. 1894-1904
    • Popa, E.R.1    Franssen, C.F.2    Limburg, P.C.3    Huitema, M.G.4    Kallenberg, C.G.5    Tervaert, J.W.6
  • 22
    • 9644270174 scopus 로고    scopus 로고
    • Circulating cytokine profile in anti-neutrophilic cytoplasmatic autoantibody-associated vasculitis: prediction of outcome?
    • Ohlsson S., Wieslander J., and Segelmark M. Circulating cytokine profile in anti-neutrophilic cytoplasmatic autoantibody-associated vasculitis: prediction of outcome?. Mediators Inflamm 13 (2004) 275-283
    • (2004) Mediators Inflamm , vol.13 , pp. 275-283
    • Ohlsson, S.1    Wieslander, J.2    Segelmark, M.3
  • 23
    • 33750363231 scopus 로고    scopus 로고
    • Plasma levels of soluble interleukin 2 receptor, soluble CD30, interleukin 10 and B cell activator of the tumour necrosis factor family during follow-up in vasculitis associated with proteinase 3-antineutrophil cytoplasmic antibodies: associations with disease activity and relapse
    • Sanders J.S., Huitma M.G., Kallenberg C.G., and Stegeman C.A. Plasma levels of soluble interleukin 2 receptor, soluble CD30, interleukin 10 and B cell activator of the tumour necrosis factor family during follow-up in vasculitis associated with proteinase 3-antineutrophil cytoplasmic antibodies: associations with disease activity and relapse. Ann Rheum Dis 65 (2006) 1484-1489
    • (2006) Ann Rheum Dis , vol.65 , pp. 1484-1489
    • Sanders, J.S.1    Huitma, M.G.2    Kallenberg, C.G.3    Stegeman, C.A.4
  • 24
    • 0025091391 scopus 로고
    • The American College of Rheumatology 1990 criteria for the classification of Churg-Strauss syndrome (allergic granulomatosis and angiitis)
    • Masi A.T., Hunder G.G., Lie J.T., Michel B.A., Bloch D.A., and Arend W.P. The American College of Rheumatology 1990 criteria for the classification of Churg-Strauss syndrome (allergic granulomatosis and angiitis). Arthritis Rheum 33 (1990) 1094-1100
    • (1990) Arthritis Rheum , vol.33 , pp. 1094-1100
    • Masi, A.T.1    Hunder, G.G.2    Lie, J.T.3    Michel, B.A.4    Bloch, D.A.5    Arend, W.P.6
  • 25
    • 0025183423 scopus 로고
    • The American College of Rheumatology 1990 criteria for the classification of Wegener's granulomatosis
    • Leavitt R.Y., Fauci A.S., Bloch D.A., Michel B.A., Hunder G.G., and Arend W.P. The American College of Rheumatology 1990 criteria for the classification of Wegener's granulomatosis. Arthritis Rheum 33 (1990) 1101-1107
    • (1990) Arthritis Rheum , vol.33 , pp. 1101-1107
    • Leavitt, R.Y.1    Fauci, A.S.2    Bloch, D.A.3    Michel, B.A.4    Hunder, G.G.5    Arend, W.P.6
  • 26
    • 34147224220 scopus 로고    scopus 로고
    • Development of comprehensive disease assessment in systemic vasculitis
    • Flossmann O., Bacon P., de Groot K., et al. Development of comprehensive disease assessment in systemic vasculitis. Ann Rheum Dis 66 (2007) 283-292
    • (2007) Ann Rheum Dis , vol.66 , pp. 283-292
    • Flossmann, O.1    Bacon, P.2    de Groot, K.3
  • 27
    • 0036674920 scopus 로고    scopus 로고
    • Detection of the production of intracellular cytokines by T lymphocytes using flow cytometry-methodologic problems
    • Marecková H., Ravdan A., Fucíková T., and Janatková I. Detection of the production of intracellular cytokines by T lymphocytes using flow cytometry-methodologic problems. Epidemiol Mikrobiol Imunol 51 (2002) 111-118
    • (2002) Epidemiol Mikrobiol Imunol , vol.51 , pp. 111-118
    • Marecková, H.1    Ravdan, A.2    Fucíková, T.3    Janatková, I.4
  • 28
    • 22344436790 scopus 로고    scopus 로고
    • Off balance: T-cells in antineutrophil cytoplasmic antibody (ANCA)-associated vasculitides
    • Lamprecht P. Off balance: T-cells in antineutrophil cytoplasmic antibody (ANCA)-associated vasculitides. Clin Exp Immunol 141 (2005) 201-210
    • (2005) Clin Exp Immunol , vol.141 , pp. 201-210
    • Lamprecht, P.1
  • 30
    • 0032907826 scopus 로고    scopus 로고
    • Cytokine profiles in Wegener's granulomatosis: predominance of type 1 (Th1) in the granulomatous inflammation
    • Csernok E., Trabandt A., Müller A., et al. Cytokine profiles in Wegener's granulomatosis: predominance of type 1 (Th1) in the granulomatous inflammation. Arthritis Rheum 42 (1999) 742-750
    • (1999) Arthritis Rheum , vol.42 , pp. 742-750
    • Csernok, E.1    Trabandt, A.2    Müller, A.3
  • 31
    • 0034893210 scopus 로고    scopus 로고
    • Th2 dominance in nasal mucosa in patients with Wegener's granulomatosis
    • Balding C.E.J., Howie A.J., Drake-Lee A.B., and Savage C.O.S. Th2 dominance in nasal mucosa in patients with Wegener's granulomatosis. Clin Exp Immunol 125 (2001) 332-339
    • (2001) Clin Exp Immunol , vol.125 , pp. 332-339
    • Balding, C.E.J.1    Howie, A.J.2    Drake-Lee, A.B.3    Savage, C.O.S.4
  • 32
    • 0033828445 scopus 로고    scopus 로고
    • Localized Wegener's granulomatosis: predominance of CD26 and IFN-gamma expression
    • Muller A., Trabandt A., Gloeckner-Hofmann K., et al. Localized Wegener's granulomatosis: predominance of CD26 and IFN-gamma expression. J Pathol 192 (2000) 113-120
    • (2000) J Pathol , vol.192 , pp. 113-120
    • Muller, A.1    Trabandt, A.2    Gloeckner-Hofmann, K.3
  • 33
    • 0038039259 scopus 로고    scopus 로고
    • Strong polarization toward Th1 immune response in ANCA-associated glomerulonephritis
    • Masutani K., Tokumoto M., Nakashima H., et al. Strong polarization toward Th1 immune response in ANCA-associated glomerulonephritis. Clin Nephrol 59 (2003) 395-405
    • (2003) Clin Nephrol , vol.59 , pp. 395-405
    • Masutani, K.1    Tokumoto, M.2    Nakashima, H.3
  • 34
    • 0033866586 scopus 로고    scopus 로고
    • Circulating cytokines and soluble CD23, CD26 and CD30 in ANCA-associated vasculitides
    • Schönermarck U., Csernok E., Trabandt A., Hansen H., and Gross W.L. Circulating cytokines and soluble CD23, CD26 and CD30 in ANCA-associated vasculitides. Clin Exp Rheumatol 18 (2000) 457-463
    • (2000) Clin Exp Rheumatol , vol.18 , pp. 457-463
    • Schönermarck, U.1    Csernok, E.2    Trabandt, A.3    Hansen, H.4    Gross, W.L.5
  • 35
  • 36
    • 47249092218 scopus 로고    scopus 로고
    • Skewed distribution of Th17 lymphocytes in patients with Wegener's granulomatosis in remission
    • Abdulahad W.H., Stegeman C.A., Limburg P.C., and Kallenberg C.G. Skewed distribution of Th17 lymphocytes in patients with Wegener's granulomatosis in remission. Arthritis Rheum 58 (2008) 2196-2205
    • (2008) Arthritis Rheum , vol.58 , pp. 2196-2205
    • Abdulahad, W.H.1    Stegeman, C.A.2    Limburg, P.C.3    Kallenberg, C.G.4
  • 37
    • 0036097722 scopus 로고    scopus 로고
    • Peripheral blood and granuloma CD4(+) CD28(-) T cells are a major source of interferon-gamma and tumor necrosis factor-alpha in Wegener's granulomatosis
    • Komocsi A., Lamprecht P., Csernok E., et al. Peripheral blood and granuloma CD4(+) CD28(-) T cells are a major source of interferon-gamma and tumor necrosis factor-alpha in Wegener's granulomatosis. Am J Pathol 160 (2002) 1717-1724
    • (2002) Am J Pathol , vol.160 , pp. 1717-1724
    • Komocsi, A.1    Lamprecht, P.2    Csernok, E.3
  • 38
    • 34648846035 scopus 로고    scopus 로고
    • CD4-positive effector memory T cells participate in disease expression in ANCA-associated vasculitis
    • Abdulahad W.H., Stegeman C.A., Limburg P.C., and Kallenberg C.G. CD4-positive effector memory T cells participate in disease expression in ANCA-associated vasculitis. Ann NY Acad Sci 1107 (2007) 22-31
    • (2007) Ann NY Acad Sci , vol.1107 , pp. 22-31
    • Abdulahad, W.H.1    Stegeman, C.A.2    Limburg, P.C.3    Kallenberg, C.G.4
  • 39
    • 0042570785 scopus 로고    scopus 로고
    • Neutrophil-activating potential of antineutrophil cytoplasm autoantibodies
    • Rarok A.A., Limburg P.C., and Kallenberg C.G. Neutrophil-activating potential of antineutrophil cytoplasm autoantibodies. J Leukoc Biol 74 (2003) 3-15
    • (2003) J Leukoc Biol , vol.74 , pp. 3-15
    • Rarok, A.A.1    Limburg, P.C.2    Kallenberg, C.G.3
  • 40
    • 0031157030 scopus 로고    scopus 로고
    • Neutrophil production of IL-12 and IL-10 in candidiasis and efficacy of IL-12 therapy in neutropenic mice
    • Romani L., Mencacci A., Cenci E., et al. Neutrophil production of IL-12 and IL-10 in candidiasis and efficacy of IL-12 therapy in neutropenic mice. J Immunol 158 (1997) 5349-5356
    • (1997) J Immunol , vol.158 , pp. 5349-5356
    • Romani, L.1    Mencacci, A.2    Cenci, E.3
  • 41
    • 27644437166 scopus 로고    scopus 로고
    • Predictors of relapse and treatment resistance in antineutrophil cytoplasmic antibody-associated small-vessel vasculitis
    • Hogan S.L., Falk R.J., Chin H., Cai J., Jennette C.E., Jennette J.C., and Nachman P.H. Predictors of relapse and treatment resistance in antineutrophil cytoplasmic antibody-associated small-vessel vasculitis. Ann Intern Med 143 (2005) 621-631
    • (2005) Ann Intern Med , vol.143 , pp. 621-631
    • Hogan, S.L.1    Falk, R.J.2    Chin, H.3    Cai, J.4    Jennette, C.E.5    Jennette, J.C.6    Nachman, P.H.7
  • 42
    • 0347755085 scopus 로고    scopus 로고
    • Different gender-associated genotype risks of Wegener's granulomatosis and microscopic polyangiitis
    • Bártfai Z., Gaede K.I., Russell K.A., Muraközy G., Müller-Quernheim J., and Specks U. Different gender-associated genotype risks of Wegener's granulomatosis and microscopic polyangiitis. Clin Immunol 109 (2003) 330-337
    • (2003) Clin Immunol , vol.109 , pp. 330-337
    • Bártfai, Z.1    Gaede, K.I.2    Russell, K.A.3    Muraközy, G.4    Müller-Quernheim, J.5    Specks, U.6
  • 44
    • 0036163354 scopus 로고    scopus 로고
    • Novel genetic association of Wegener's granulomatosis with the interleukin 10 gene
    • Zhou Y., Giscombe R., Huang D., and Lefvert A.K. Novel genetic association of Wegener's granulomatosis with the interleukin 10 gene. J Rheumatol 29 (2002) 317-320
    • (2002) J Rheumatol , vol.29 , pp. 317-320
    • Zhou, Y.1    Giscombe, R.2    Huang, D.3    Lefvert, A.K.4
  • 45
    • 34548410407 scopus 로고    scopus 로고
    • TNF-alpha bioactivity-inhibiting therapy in ANCA-associated vasculitis: clinical and experimental considerations
    • Huugen D., Cohen Tervaert J.W., and Heeringa P. TNF-alpha bioactivity-inhibiting therapy in ANCA-associated vasculitis: clinical and experimental considerations. Clin J Am Soc Nephrol 1 (2006) 1100-1107
    • (2006) Clin J Am Soc Nephrol , vol.1 , pp. 1100-1107
    • Huugen, D.1    Cohen Tervaert, J.W.2    Heeringa, P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.