The use of small molecule high-throughput screening to identify inhibitors of the proteinase 3-NB1 interaction

Clinical and Experimental Immunology

Volumn 161, Issue 2, 2010, Pages 389-396

  Choi, M ^a   Eulenberg, C ^a   Rolle, S ^a   Von Kries, J P ^b   Luft, F C ^a   Kettritz, R ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b LEIBNIZ INSTITUT FÜR MOLEKULARE PHARMAKOLOGIE   (Germany)

Author keywords

ANCA; compound screening; NB1; neutrophils; proteinase 3

Indexed keywords

CELL SURFACE RECEPTOR; MYELOBLASTIN; NEUTROPHIL CYTOPLASMIC ANTIBODY; PROTEIN NB1; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; CELL STRAIN HEK293; CONTROLLED STUDY; FLOW CYTOMETRY; GENE EXPRESSION; GENETIC TRANSFECTION; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; MOLECULAR LIBRARY; NEUTROPHIL; PRIORITY JOURNAL; REPRODUCIBILITY; SMALL VESSEL VASCULITIS; VALIDATION PROCESS;

ANTIBODIES, ANTINEUTROPHIL CYTOPLASMIC; CELL LINE; CELL MEMBRANE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG EVALUATION, PRECLINICAL; FLOW CYTOMETRY; HUMANS; ISOANTIGENS; MEMBRANE GLYCOPROTEINS; MOLECULAR STRUCTURE; MYELOBLASTIN; NEUTROPHILS; PHARMACEUTICAL PREPARATIONS; PROTEIN BINDING; PROTEIN TRANSPORT; RECEPTORS, CELL SURFACE; TRANSFECTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 77954652310     PISSN: 00099104     EISSN: 13652249     Source Type: Journal    
DOI: 10.1111/j.1365-2249.2010.04174.x     Document Type: Article

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