Microglia in development: Linking brain wiring to brain environment

Neuron Glia Biology

Volumn 7, Issue 1, 2012, Pages 77-83

  Paolicelli, Rosa C ^a   Gross, Cornelius T ^a  

^a EUROPEAN MOLECULAR BIOLOGY LABORATORY EMBL   (Italy)

Author keywords

development; mice; Microglia; pruning; synaptogenesis

Indexed keywords

COMPLEMENT COMPONENT C1Q; GLIAL FIBRILLARY ACIDIC PROTEIN;

BRAIN DEVELOPMENT; BRAIN INJURY; CELL ACTIVATION; CELL FUNCTION; CELL INTERACTION; CELL MOTILITY; HUMAN; INFLAMMATION; MICROGLIA; NERVE CELL; NERVE CELL NETWORK; NEUROPATHOLOGY; NONHUMAN; PHAGOCYTOSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVIEW; SYNAPSE;

ANIMALS; BRAIN; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HUMANS; MICROGLIA; SYNAPSES;

MUS;

EID: 84864643296     PISSN: 1740925X     EISSN: 17410533     Source Type: Journal    
DOI: 10.1017/S1740925X12000105     Document Type: Review

References (67)

1. Ajami B., Bennett J.L., Krieger C., Tetzlaff W. and Rossi F.M. (2007) Local self-renewal can sustain CNS microglia maintenance and func-tion throughout adult life. Nature Neuroscience 10, 1538-1543.
2. Alliot F., Godin I. and Pessac B. (1999) Microglia derive from progeni-tors, originating from the yolk sac, and which proliferate in the brain. Brain Research Development Brain Research 117, 145-152.
3. Biber K., Neumann H., Inoue K. and Boddeke H.W. (2007) Neuronal 'On' and 'Off' signals control microglia. Trends in Neurosciences 30, 596-602.
4. Bilbo S.D., Barrientos R.M., Eads A.S., Northcutt A., Watkins L.R., Rudy J.W. et al. (2008) Early-life infection leads to altered BDNF and IL-1beta mRNA expression in rat hippocampus followinglearning in adulthood. Brain Behavior Immunity 22, 451-455.
5. Bilbo S.D., Biedenkapp J.C., Der-Avakian A., Watkins L.R., Rudy J.W. and Maier S.F. (2005) Neonatal infection-induced memory impair-ment after lipopolysaccharide in adulthood is prevented via caspase-1 inhibition. Journal of Neuroscience 25, 8000-8009.
6. Bilbo S.D., Rudy J.W., Watkins L.R. and Maier S.F. (2006) A behavi oural characterization of neonatal infection-facilitated memory impairment in adult rats. Behavioural Brain Research 169, 39-47.
7. Block M.L., Zecca L. and Hong J.-S. (2007) Microglia-mediated neuro-toxicity: uncovering the molecular mechanisms. Nature Reviews Neuroscience 8, 57-69.
8. Broderick C., Duncan L., Taylor N. and Dick A.D. (2000) IFN and LPS mediatedIL-10-dependent suppression ofretinal microglial activation. Investigative Ophthalmolgy and Visual Science 41, 2613-2622.
9. Brown A.S. and Derkits E.J. (2010) Prenatal infection and schizophrenia: a review of epidemiologic and translational studies. American Journal ofPsychiatry 167, 261-280.
10. Buehler M.R. (2011) A proposed mechanism for autism: an aberrant neu-roimmune response manifested as a psychiatric disorder. Medical Hypotheses 76, 863-870.
11. Chan W.Y., Kohsaka S. and Rezaie P. (2007) The origin and cell lineage of microglia: new concepts. Brain Research Reviews 53, 344-354.
12. Chang Y.P., Fang K.M., Lee T.I. and Tzeng S.F.J. (2006) Regulation of microglial activities by glial cell line derived neurotrophic factor. Cell Biochemistry 97, 501-511.
13. Chen S.-K., Tvrdik P., Peden E., Cho S., Wu S., Spangrude G. et al. (2010) Hematopoietic origin of pathological grooming in Hoxb8 mutant mice. Cell 141, 775-785.
14. Ciaranello A.-L. and Ciaranello R.D. (1995) The neurobiology ofinfan-tile autism. Annual Review of Neuroscience 18, 101-128.
15. Cruz-Martin A., Crespo M. and Portera-Cailliau C. (2010) Delayed stabilization of dendritic spines in fragile X mice. Journal of Neuroscience 30, 7793-7803.
16. Cuadros M.A., Martin C., Coltey P., Almendros A. and Navascués J. (1993) First appearance, distribution, and origin of macrophages in the early development of the avian central nervous system. Journal ofComparative Neurology 330, 113-129.
17. Dalmau I., Finsen B., Zimmer J., González B. and Castellano B. (1998) Development of microglia in the postnatal rat hippocampus. Hippocampus 8, 458-474.
18. Davalos D., Grutzendler J., Yang G., Kim J.V., Zuo Y., Jung S. et al. (2005) ATP mediates rapid microglial response to local brain injury in vivo. Nature Neuroscience 8, 752-758.
19. Del Rio-Hortega P. (1932) Microglia. In Penfield W. (ed.) Cytology and Cellular Pathology of the Nervous System. Hoeber, New York. pp. 481-534.
20. Gilmore J.H. and Jarskog L.F. (1997) Exposure to infection and brain development: cytokines in the pathogenesis of schizophrenia. Schizophrenia Research 24, 365-367.
21. Ginhoux F., Greter M., Leboeuf M., Nandi S., See P., Gokhan S. et al. (2010) Fate mapping analysis reveals that adult microglia derive from primitive macrophages. Science 330, 841-845.
22. Graeber M.B. (2010) Changing face of microglia. Science 330, 783-788.
23. Hanisch U.-K. and Kettenmann H. (2007) Microglia: active sensor and versatile effector cells in the normal and pathologic brain. Nature Neuroscience 10, 1387-1394.
24. Herbomel P., Thisse B. and Thisse C. (2001) Zebrafish early macro-phages colonize cephalic mesenchyme and developing brain, retina, and epidermis through a M-CSF receptor-dependent invasive process. Devlopmental Biology 238, 274-288.
25. Hristova M., Cuthill D., Zbarsky V., Acosta-Saltos A., Wallace A., Blight K. et al. (2010) Activation and deactivation of periventricular white matter phagocytes during postnatal mouse development. Glia 58, 11-28.
26. Jung S., Aliberti J., Graemmel P., Sunshine M.J., Kreutzberg G.W., Sher A. et al. (2000) Analysis offractalkine receptor CX(3)CR1 func-tion by targeted deletion and green flourescent protein reporter gene insertion. Molecular Cellular Biology 20, 4106-4114.
27. Kitamura Y., Takata K., Inden M., Tsuchiya D., Yanagisawa D., Nakata J. et al. (2004) Intracerebroventricular injection of microglia protects against focal brain ischemia. Journal of Pharmacological Sciences. 94, 203-206.
28. Koenigsknecht-Talboo J. and Landreth G.E. (2005) Microglial phagocy-tosis induced by fibrillar beta-amyloid and IgGs are differentially regu-lated by proinflammatory cytokines. Journal of Neuroscience 25, 8240-8249.
29. Krabbe G., Matyash V., Pannasch U., Mamer L., Boddeke H.W. and Kettenmann H. (2012) Activation of serotonin receptors promotes microglial injury-induced motility but attenuates phagocytic activity. Brain Behavior and Immunity 26, 419-428.
30. Lawson L.J., Perry V.H., Dri P. and Gordon S. (1990) Heterogeneity in the distribution and morphology of microglia in the normal adult mouse brain. Neuroscience 39, 151-170.
31. Lee T.I., Yang C.S., Fang K.M. and Tzeng S.F. (2009) Role of ciliary neurotrophic factor in microglial phagocytosis. Neurochemical Research 34, 109-117.
32. Ling E.A., Kaur C., Yick T.Y. and Wong W.C. (1990) Immunocytochemical localization of CR3 complement receptors with OX-42 in amoeboid microglia in postnatal rats. Anatomy and Embryology 182, 481-486.
33. Linnartz B., Kopatz J., Tenner A.J. and Neumann H. (2012) Sialic acid on the neuronal glycocalyx prevents complement c1 binding and complement receptor-3-mediated removal by microglia. Journal of Neuroscience 32, 946-952.
34. Lyck L., Santamaria I.D., Pakkenberg B., Chemnitz J., Schrøder H.D., Finsen B. et al. (2009) An empirical analysis of the precision of esti-mating the numbers of neurons and glia in human neocortex using a fractionator-design with sub-sampling. Journal of Neuroscience Methods 182, 143-156.
35. Mallat M., Maríin-Teva J.L. and Chéret C. (2005) Phagocytosis in the developing CNS: more than clearing the corpses. Current Opinion in Neurobiology 15, 101-107.
36. Maríin-Teva J.L., Dusart I., Colin C., Gervais A., van Rooijen N. and Mallat M. (2004) Microglia promote the death of developing Purkinje cells. Neuron 41, 535-547.
37. McAlonan G.M., Li Q. and Cheung C. (2010) The timing and specificity of prenatal immune risk factors for autism modeled in the mouse and relevance to schizophrenia. Neurosignals 18, 129-139.
38. Meyer U., Feldon J. and Dammann O. (2011) Schizophrenia and autism: both shared and disorder-specific pathogenesis via perinatal inflam-mation? Pediatric Research 69, 26R-33R.
39. Meyer U., Feldon J. and Fatemi S.H. (2009) In-vivo rodent models for the experimental investigation of prenatal immune activation effects in neurodevelopmental brain disorders. Neuroscience and Biobehavioral Reviews 33, 1061-1079.
40. Meyer U., Murray P.J., Urwyler A., Yee B.K., Schedlowski M. and Feldon J. (2008) Adult behavioral and pharmacological dysfunctions following disruption of the fetal brain balance between pro inflammatory and IL-10-mediated anti-inflammatory signaling. Molecular Psychiatry 13, 208-221.
41. Meyer U., Nyffeler M., Engler A., Urwyler A., Schedlowski M., Knuesel I. et al. (2006) The time ofprenatal immune challenge determines the specificity of inflammation-mediated brain and behavioral pathology. Journal of Neuroscience 26, 4752-4762.
42. Ming G.L. and Song H. (2011) Adult neurogenesis in the mammalian brain: significant answers and significant questions. Neuron 70, 687-702.
43. Mitrasinovic O.M., Vincent V.A., Simsek D. and Murphy G.M. Jr (2003) Macrophage colony stimulating factor promotes phagocytosis by murine microglia. Neuroscience Letters 344, 185-188.
44. Mody M., Cao Y., Cui Z., Tay K.-Y., Shyong A., Shimizu E. et al. (2001) Genome-wide gene expression profiles of the developing mouse hippocampus. Proceedings of the National Academy ofSciences of the U.S.A. 98, 8862-8867.
45. Monje M.L., Toda H. and Palmer T.D. (2003) Inflammatory blockade restores adult hippocampal neurogenesis. Science 302, 1760-1765.
46. Mount M.P., Lira A., Grimes D., Smith P.D., Faucher S., Slack R. et al. (2007) Involvement of interferon-gamma in microglial-mediated loss ofdopaminergic neurons. Journal of Neuroscience. 27, 3328-3337.
47. Nagano T., Kimura S.H. and Takemura M. (2010) Prostaglandin E2 reduces amyloid beta-induced phagocytosis in cultured rat microglia. Brain Research 1323, 11-17.
48. Nimmerjahn A., Kirchhoff F. and Helmchen F. (2005) Resting micro-glial cells are highly dynamic surveillants of brain parenchyma in vivo. Science 308, 1314-1318.
49. Pan X.D., Zhu Y.G., Lin N., Zhang J., Ye Q.Y., Huang H.P. et al. (2011) Microglial phagocytosis induced by fibrillar ß-amyloid is attenuated by oligomeric ß-amyloid: implications for Alzheimer's disease. Molecular Neurodegeneration 6, 45.
50. Paolicelli R.C., Bolasco G., Pagani F., Maggi L., Scianni M., Panzanelli P. et al. (2011) Synaptic pruning by microglia is necessary for normal brain development. Science 233, 1456-1458.
51. Patterson P.H. (2011) Maternal infection and immune involvement in autism. Trends in Molecular Medicine 17, 389-394.
52. Peri F. and Nüsslein-Volhard C. (2008) Live imaging ofneuronal degra-dation by microglia reveals a role for v0-ATPase a1 in phagosomal fusion in vivo. Cell 133, 916-927.
53. Pont-Lezica L., Béchade C., Belarif-Cantaut Y., Pascual O. and Bessis A. (2011) Physiological roles of microglia during development. Journal of Neurochemistry 119, 901-908.
54. Ransohoff R.M. and Cardona A.E. (2010) The myeloid cells of the central nervous system parenchyma. Nature 468, 253-262.
55. Saijo K. and Glass C.K. (2011) Microglial cell origin and phenotypes in health and disease. Nature Reviews Immunology 11, 775-787.
56. Santos A.M., Calvente R., Tassi M., Carrasco M.-C., Martín-Oliva D., Martín-Teva J.L. et al. (2008) Embryonic and postnatal development of microglial cells in the mouse retina. Journal of Comparative Neurology 506, 224-239.
57. Schafer D.P. and Stevens B. (2010) Synapse elimination during develop-ment and disease: immune molecules take centre stage. Biochemical Society Transactions 38, 476-481.
58. Sierra A., Encinas J.M., Deudero J.J.P., Chancey J.H., Enikolopov G., Overstreet-Wadiche L.S. et al. (2010) Microglia shape adult hippo-campal neurogenesis through apoptosis-coupled phagocytosis. Cell Stem Cell 7, 483-495.
59. Smith S.E., Li J., Garbett K., Mirnics K. and Patterson P.H. (2007) Maternal immune activation alters fetal brain development through interleukin-6. Journal of Neuroscience 27, 10695-10702.
60. Stevens B., Allen N.J., Vazquez L.E., Howell G.R., Christopherson K.S., Nouri N. et al. (2007) The classical complement cascade mediates CNS synapse elimination. Cell 131, 1164-1178.
61. Thomas A., Gasque P., Vaudry D., Gonzalez B. and Fontaine M. (2000) Expression of a complete and functional complement system by human neuronal cells in vitro. International Immunology 12, 1015-1023.
62. Tremblay M.-E., Lowery R.L. and Majewska A.K. (2010) Microglial interactions with synapses are modulated by visual experience. PLoS Biology 8, e1000527.
63. Verney C., Monier A., Fallet-Bianco C. and Gressens P. (2010) Early microglial colonization of the human forebrain and possible involve-ment in periventricular white-matter injury of preterm infants. Journal of Anatomy 217, 436-448.
64. Vuillermot S., Joodmardi E., Perlmann T., Ove Ogren S., Feldon J. and Meyer U. (2012) Prenatal immune activation interacts with genetic nurr1 deficiency in the development of attentional impairments. Journal of Neuroscience 32, 436-451.
65. Wake H., Moorhouse A.J., Jinno S., Kohsaka S. and Nabekura J. (2009) Resting microglia directly monitor the functional state of synapses in vivo and determine the fate of ischemic terminals. Journal of Neuroscience 29, 3974-3980.
66. Wakselman S., Béchade C., Roumier A., Bernard D., Triller A. and Bessis A. (2008) Developmental neuronal death in hippocampus requires the microglial CD11b integrin and DAP12 immunoreceptor. Journal of Neuroscience 28, 8138-8143.
67. Walker D.G., Kim S.U. and McGeer P.L. (1995) Complement and cyto-kine gene expression in cultured microglial derived from postmortem human brains. Journal of Neuroscience Research 40, 478-493.