Role of ciliary neurotrophic factor in microglial phagocytosis

Neurochemical Research

Volumn 34, Issue 1, 2009, Pages 109-117

  Lee, Tsung I ^a   Yang, Chung Shi ^b,c   Fang, Kuan Ming ^a   Tzeng, Shun Fen ^a  

^a NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^b NATIONAL HEALTH RESEARCH INSTITUTES   (Taiwan)

^c NATIONAL CHI NAN UNIVERSITY   (Taiwan)

Author keywords

v Integrin; Calcium; CNTF; Microglia; Phagocytosis

Indexed keywords

CALCIUM ION; CD51 ANTIGEN; CHELATING AGENT; CILIARY NEUROTROPHIC FACTOR; ETHYLENE GLYCOL 1,2 BIS(2 AMINOPHENYL) ETHER N,N,N',N' TETRAACETIC ACID; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; INTEGRIN; SCAVENGER;

ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CALCIUM SIGNALING; CELL LINE; CENTRAL NERVOUS SYSTEM; GLIA CELL; IMAGING; MACROPHAGE; MICROGLIA; NERVE CELL MEMBRANE; NONHUMAN; PHAGOCYTOSIS; PRIORITY JOURNAL; RAT; UPREGULATION;

ANIMALS; CALCIUM; CELL LINE; CELLS, CULTURED; CILIARY NEUROTROPHIC FACTOR; INTEGRIN ALPHAV; INTERLEUKIN-1BETA; MICE; MICROGLIA; PHAGOCYTOSIS; RATS; TUMOR NECROSIS FACTOR-ALPHA; UP-REGULATION;

RATTUS;

EID: 58149469087     PISSN: 03643190     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11064-008-9682-0     Document Type: Article

References (39)

1. UK Hanisch H Kettenmann 2007 Microglia: active sensor and versatile effector cells in the normal and pathologic brain Nat Neurosci 10 1387 1394
2. GW Kreutzberg 1996 Microglia: a sensor for pathological events in the CNS Trends Neurosci 19 312 318
3. GA Garden T Moller 2006 Microglia biology in health and disease J Neuroimmune Pharmacol 1 127 137
4. S Elkabes EM DiCicco-Bloom IB Black 1996 Brain microglia/macrophages express neurotrophins that selectively regulate microglial proliferation and function J Neurosci 16 2508 2521
5. W Cammer H Zhang 1996 Carbonic anhydrase II in microglia in forebrains of neonatal rats J Neuroimmunol 67 131 136
6. A Bessis C Bechade D Bernard A Roumier 2007 Microglial control of neuronal death and synaptic properties Glia 55 233 238
7. M Schwartz 2003 Macrophages and microglia in central nervous system injury: are they helpful or harmful? J Cereb Blood Flow Metab 23 385 394
8. B Liu JS Hong 2003 Role of microglia in inflammation-mediated neurodegenerative diseases: mechanisms and strategies for therapeutic intervention J Pharmacol Exp Ther 304 1 7
9. D Giulian M Corpuz 1993 Microglial secretion products and their impact on the nervous system Adv Neurol 59 315 320
10. S David C Bouchard O Tsatas N Giftochristos 1990 Macrophages can modify the nonpermissive nature of the adult mammalian central nervous system Neuron 5 463 469
11. LF Lin D Mismer JD Lile LG Armes ET Butler 3rd JL Vannice F Collins 1989 Purification, cloning, and expression of ciliary neurotrophic factor (CNTF) Science 246 1023 1025
12. R Adler KB Landa M Manthorpe S Varon 1979 Cholinergic neuronotrophic factors: intraocular distribution of trophic activity for ciliary neurons Science 204 1434 1436
13. PM Richardson 1994 Ciliary neurotrophic factor: a review Pharmacol Ther 63 187 198
14. B Stankoff MS Aigrot F Noel A Wattilliaux B Zalc C Lubetzki 2002 Ciliary neurotrophic factor (CNTF) enhances myelin formation: a novel role for CNTF and CNTF-related molecules J Neurosci 22 9221 9227
15. V Mittoux JM Joseph F Conde S Palfi C Dautry T Poyot J Bloch N Deglon S Ouary EA Nimchinsky E Brouillet PR Hof M Peschanski P Aebischer P Hantraye 2000 Restoration of cognitive and motor functions by ciliary neurotrophic factor in a primate model of Huntington's disease Hum Gene Ther 11 1177 1187
16. C Escartin K Pierre A Colin E Brouillet T Delzescaux M Guillermier M Dhenain N Deglon P Hantraye L Pellerin G Bonvento 2007 Activation of astrocytes by CNTF induces metabolic plasticity and increases resistance to metabolic insults J Neurosci 27 7094 7104
17. MA Kahn JA Ellison GJ Speight J de Vellis 1995 CNTF regulation of astrogliosis and the activation of microglia in the developing rat central nervous system Brain Res 685 55 67
18. Krady JK, Lin HW, Liberto CM, Basu A, Kremlev SG, Levison SW (2008) Ciliary neurotrophic factor and interleukin-6 differentially activate microglia. J Neurosci Res
19. I Jutras M Desjardins 2005 Phagocytosis: at the crossroads of innate and adaptive immunity Annu Rev Cell Dev Biol 21 511 527
20. A Witting P Muller A Herrmann H Kettenmann C Nolte 2000 Phagocytic clearance of apoptotic neurons by Microglia/Brain macrophages in vitro: involvement of lectin-, integrin-, and phosphatidylserine-mediated recognition J Neurochem 75 1060 1070
21. E Blasi R Barluzzi V Bocchini R Mazzolla F Bistoni 1990 Immortalization of murine microglial cells by a v-raf/v-myc carrying retrovirus J Neuroimmunol 27 229 237
22. SF Tzeng HY Huang TI Lee JK Jwo 2005 Inhibition of lipopolysaccharide- induced microglial activation by preexposure to neurotrophin-3 J Neurosci Res 81 666 676
23. SF Tzeng JL Lee JS Kuo CS Yang P Murugan L Ai Tai K Chu Hwang 2002 Effects of malonate C60 derivatives on activated microglia Brain Res 940 61 68
24. KD McCarthy J de Vellis 1980 Preparation of separate astroglial and oligodendroglial cell cultures from rat cerebral tissue J Cell Biol 85 890 902
25. YP Chang KM Fang TI Lee SF Tzeng 2006 Regulation of microglial activities by glial cell line derived neurotrophic factor J Cell Biochem 97 501 511
26. S Koizumi Y Shigemoto-Mogami K Nasu-Tada Y Shinozaki K Ohsawa M Tsuda BV Joshi KA Jacobson S Kohsaka K Inoue 2007 UDP acting at P2Y6 receptors is a mediator of microglial phagocytosis Nature 446 1091 1095
27. DM Schrijvers W Martinet GR De Meyer L Andries AG Herman MM Kockx 2004 Flow cytometric evaluation of a model for phagocytosis of cells undergoing apoptosis J Immunol Methods 287 101 108
28. HY Hsiao OT Mak CS Yang YP Liu KM Fang SF Tzeng 2007 TNF-alpha/IFN-gamma- induced iNOS expression increased by prostaglandin E2 in rat primary astrocytes via EP2-evoked cAMP/PKA and intracellular calcium signaling Glia 55 214 223
29. MS Boran MA Baltrons A Garcia 2008 The ANP-cGMP-protein kinase G pathway induces a phagocytic phenotype but decreases inflammatory gene expression in microglial cells Glia 56 394 411
30. V Bocchini JC Artault G Rebel H Dreyfus R Massarelli 1988 Phagocytosis of polystyrene latex beads by rat brain microglia cell cultures is increased by treatment with gangliosides Dev Neurosci 10 270 276
31. P Dersch RR Isberg 2000 An immunoglobulin superfamily-like domain unique to the Yersinia pseudotuberculosis invasin protein is required for stimulation of bacterial uptake via integrin receptors Infect Immun 68 2930 2938
32. RR Isberg Z Hamburger P Dersch 2000 Signaling and invasin-promoted uptake via integrin receptors Microbes Infect 2 793 801
33. ML Albert JI Kim RB Birge 2000 Alphavbeta5 integrin recruits the CrkII-Dock180-rac1 complex for phagocytosis of apoptotic cells Nat Cell Biol 2 899 905
34. B Leitinger A McDowall P Stanley N Hogg 2000 The regulation of integrin function by Ca(2+) Biochim Biophys Acta 1498 91 98
35. ME Jaconi DP Lew JL Carpentier KE Magnusson M Sjogren O Stendahl 1990 Cytosolic free calcium elevation mediates the phagosome-lysosome fusion during phagocytosis in human neutrophils J Cell Biol 110 1555 1564
36. J Bloch AC Bachoud-Levi N Deglon JP Lefaucheur L Winkel S Palfi JP Nguyen C Bourdet V Gaura P Remy P Brugieres MF Boisse S Baudic P Cesaro P Hantraye P Aebischer M Peschanski 2004 Neuroprotective gene therapy for Huntington's disease, using polymer-encapsulated cells engineered to secrete human ciliary neurotrophic factor: results of a phase I study Hum Gene Ther 15 968 975
37. M Hashimoto A Nitta H Fukumitsu H Nomoto L Shen S Furukawa 2005 Involvement of glial cell line-derived neurotrophic factor in activation processes of rodent macrophages J Neurosci Res 79 476 487
38. K McPhillips WJ Janssen M Ghosh A Byrne S Gardai L Remigio DL Bratton JL Kang P Henson 2007 TNF-alpha inhibits macrophage clearance of apoptotic cells via cytosolic phospholipase A2 and oxidant-dependent mechanisms J Immunol 178 8117 8126
39. J Koenigsknecht G Landreth 2004 Microglial phagocytosis of fibrillar beta-amyloid through a beta1 integrin-dependent mechanism J Neurosci 24 9838 9846