-
1
-
-
33846649116
-
Efficacy and safety of anticoagulant treatment in acute cardioembolic stroke: A meta-analysis of randomized controlled trials
-
M. Paciaroni, G. Agnelli, S. Micheli, and V. Caso Efficacy and safety of anticoagulant treatment in acute cardioembolic stroke: a meta-analysis of randomized controlled trials Stroke 38 2007 423 430
-
(2007)
Stroke
, vol.38
, pp. 423-430
-
-
Paciaroni, M.1
Agnelli, G.2
Micheli, S.3
Caso, V.4
-
2
-
-
42349095894
-
Thrombolytic toxicity: Blood brain barrier disruption in human ischemic stroke
-
C.S. Kidwell, L. Latour, J.L. Saver, J.R. Alger, S. Starkman, and G. Duckwiler Thrombolytic toxicity: blood brain barrier disruption in human ischemic stroke Cerebrovasc Dis 25 2008 338 343
-
(2008)
Cerebrovasc Dis
, vol.25
, pp. 338-343
-
-
Kidwell, C.S.1
Latour, L.2
Saver, J.L.3
Alger, J.R.4
Starkman, S.5
Duckwiler, G.6
-
3
-
-
77953648503
-
A critical assessment of edaravone acute ischemic stroke efficacy trials: Is edaravone an effective neuroprotective therapy?
-
P.A. Lapchak A critical assessment of edaravone acute ischemic stroke efficacy trials: is edaravone an effective neuroprotective therapy? Expert Opin Pharmacother 11 2010 1753 1763
-
(2010)
Expert Opin Pharmacother
, vol.11
, pp. 1753-1763
-
-
Lapchak, P.A.1
-
4
-
-
79952113397
-
Citicoline for acute ischemic stroke in Mexican hospitals: A retrospective postmarketing analysis
-
C. Leon-Jimenez, E. Chiquete, C. Cantu, M.J. Miramontes-Saldana, M.A. Andrade-Ramos, and J.L. Ruiz-Sandoval Citicoline for acute ischemic stroke in Mexican hospitals: a retrospective postmarketing analysis Methods Find Exp Clin Pharmacol 32 2010 325 330
-
(2010)
Methods Find Exp Clin Pharmacol
, vol.32
, pp. 325-330
-
-
Leon-Jimenez, C.1
Chiquete, E.2
Cantu, C.3
Miramontes-Saldana, M.J.4
Andrade-Ramos, M.A.5
Ruiz-Sandoval, J.L.6
-
5
-
-
33747185837
-
Prior use of antithrombotic agents and neurological functional outcome at discharge in patients with ischemic stroke
-
M. Paciaroni, G. Agnelli, V. Caso, M. Venti, A. Alberti, and P. Milia Prior use of antithrombotic agents and neurological functional outcome at discharge in patients with ischemic stroke J Thromb Haemost 4 2006 1957 1961
-
(2006)
J Thromb Haemost
, vol.4
, pp. 1957-1961
-
-
Paciaroni, M.1
Agnelli, G.2
Caso, V.3
Venti, M.4
Alberti, A.5
Milia, P.6
-
6
-
-
0034648757
-
Thrombin signalling and protease-activated receptors
-
S.R. Coughlin Thrombin signalling and protease-activated receptors Nature 407 2000 258 264
-
(2000)
Nature
, vol.407
, pp. 258-264
-
-
Coughlin, S.R.1
-
7
-
-
67650809043
-
Irreversible platelet activation requires protease-activated receptor 1-mediated signaling to phosphatidylinositol phosphates
-
M. Holinstat, A.M. Preininger, S.B. Milne, W.J. Hudson, H.A. Brown, and H.E. Hamm Irreversible platelet activation requires protease-activated receptor 1-mediated signaling to phosphatidylinositol phosphates Mol Pharmacol 76 2009 301 313
-
(2009)
Mol Pharmacol
, vol.76
, pp. 301-313
-
-
Holinstat, M.1
Preininger, A.M.2
Milne, S.B.3
Hudson, W.J.4
Brown, H.A.5
Hamm, H.E.6
-
8
-
-
0033613269
-
Protease-activated receptor 1 is the primary mediator of thrombin-stimulated platelet procoagulant activity
-
H. Andersen, D.L. Greenberg, K. Fujikawa, W. Xu, D.W. Chung, and E.W. Davie Protease-activated receptor 1 is the primary mediator of thrombin-stimulated platelet procoagulant activity Proc Natl Acad Sci U S A 96 1999 11189 11193
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 11189-11193
-
-
Andersen, H.1
Greenberg, D.L.2
Fujikawa, K.3
Xu, W.4
Chung, D.W.5
Davie, E.W.6
-
9
-
-
0036285822
-
Four different types of protease-activated receptors are widely expressed in the brain and are up-regulated in hippocampus by severe ischemia
-
F. Striggow, M. Riek-Burchardt, A. Kiesel, W. Schmidt, P. Henrich-Noack, and J. Breder Four different types of protease-activated receptors are widely expressed in the brain and are up-regulated in hippocampus by severe ischemia Eur J Neurosci 14 2001 595 608
-
(2001)
Eur J Neurosci
, vol.14
, pp. 595-608
-
-
Striggow, F.1
Riek-Burchardt, M.2
Kiesel, A.3
Schmidt, W.4
Henrich-Noack, P.5
Breder, J.6
-
10
-
-
0032100686
-
2 +]i-inducing protease-activated receptors (par-1 and par-2) in rat astrocytes and c6 glioma cells
-
2 +]i-inducing protease-activated receptors (par-1 and par-2) in rat astrocytes and c6 glioma cells Neuroscience 86 1998 597 609
-
(1998)
Neuroscience
, vol.86
, pp. 597-609
-
-
Ubl, J.J.1
Vohringer, C.2
Reiser, G.3
-
11
-
-
54949143163
-
Prothrombin/thrombin and the thrombin receptors par-1 and par-4 in the brain: Localization, expression and participation in neurodegenerative diseases
-
E. Sokolova, and G. Reiser Prothrombin/thrombin and the thrombin receptors par-1 and par-4 in the brain: localization, expression and participation in neurodegenerative diseases Thromb Haemost 100 2008 576 581
-
(2008)
Thromb Haemost
, vol.100
, pp. 576-581
-
-
Sokolova, E.1
Reiser, G.2
-
12
-
-
9144238400
-
Protease-activated receptors in neuronal development, neurodegeneration, and neuroprotection: Thrombin as signaling molecule in the brain
-
T. Rohatgi, F. Sedehizade, K.G. Reymann, and G. Reiser Protease-activated receptors in neuronal development, neurodegeneration, and neuroprotection: thrombin as signaling molecule in the brain Neuroscientist 10 2004 501 512
-
(2004)
Neuroscientist
, vol.10
, pp. 501-512
-
-
Rohatgi, T.1
Sedehizade, F.2
Reymann, K.G.3
Reiser, G.4
-
13
-
-
0242363128
-
The contribution of protease-activated receptor 1 to neuronal damage caused by transient focal cerebral ischemia
-
C.E. Junge, T. Sugawara, G. Mannaioni, S. Alagarsamy, P.J. Conn, and D.J. Brat The contribution of protease-activated receptor 1 to neuronal damage caused by transient focal cerebral ischemia Proc Natl Acad Sci U S A 100 2003 13019 13024
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 13019-13024
-
-
Junge, C.E.1
Sugawara, T.2
Mannaioni, G.3
Alagarsamy, S.4
Conn, P.J.5
Brat, D.J.6
-
14
-
-
2942608168
-
Protease-activated receptor-1 in human brain: Localization and functional expression in astrocytes
-
C.E. Junge, C.J. Lee, K.B. Hubbard, Z. Zhang, J.J. Olson, and J.R. Hepler Protease-activated receptor-1 in human brain: localization and functional expression in astrocytes Exp Neurol 188 2004 94 103
-
(2004)
Exp Neurol
, vol.188
, pp. 94-103
-
-
Junge, C.E.1
Lee, C.J.2
Hubbard, K.B.3
Zhang, Z.4
Olson, J.J.5
Hepler, J.R.6
-
15
-
-
64249152749
-
Protease-activated receptor 1-dependent neuronal damage involves NMDA receptor function
-
C.E. Hamill, G. Mannaioni, P. Lyuboslavsky, A.A. Sastre, and S.F. Traynelis Protease-activated receptor 1-dependent neuronal damage involves NMDA receptor function Exp Neurol 217 2009 136 146
-
(2009)
Exp Neurol
, vol.217
, pp. 136-146
-
-
Hamill, C.E.1
Mannaioni, G.2
Lyuboslavsky, P.3
Sastre, A.A.4
Traynelis, S.F.5
-
16
-
-
4544359022
-
Par-1 deficiency protects against neuronal damage and neurologic deficits after unilateral cerebral hypoxia/ischemia
-
E.E. Olson, P. Lyuboslavsky, S.F. Traynelis, and R.J. McKeon Par-1 deficiency protects against neuronal damage and neurologic deficits after unilateral cerebral hypoxia/ischemia J Cereb Blood Flow Metab 24 2004 964 971
-
(2004)
J Cereb Blood Flow Metab
, vol.24
, pp. 964-971
-
-
Olson, E.E.1
Lyuboslavsky, P.2
Traynelis, S.F.3
McKeon, R.J.4
-
17
-
-
14644393684
-
Perspective: Machines for RNAi
-
Y. Tomari, and P.D. Zamore Perspective: machines for RNAi Genes Dev 19 2005 517 529
-
(2005)
Genes Dev
, vol.19
, pp. 517-529
-
-
Tomari, Y.1
Zamore, P.D.2
-
18
-
-
48249088866
-
Molecular biology. RNA interference in the nucleus
-
G. Meister Molecular biology. RNA interference in the nucleus Science 321 2008 496 497
-
(2008)
Science
, vol.321
, pp. 496-497
-
-
Meister, G.1
-
19
-
-
0035905766
-
Role for a bidentate ribonuclease in the initiation step of RNA interference
-
E. Bernstein, A.A. Candy, S.M. Hammond, and G.J. Hannon Role for a bidentate ribonuclease in the initiation step of RNA interference Nature 409 2001 363 366
-
(2001)
Nature
, vol.409
, pp. 363-366
-
-
Bernstein, E.1
Candy, A.A.2
Hammond, S.M.3
Hannon, G.J.4
-
20
-
-
0347988235
-
Nuclear export of microRNA precursors
-
E. Lund, S. Gottingen, A. Calando, J.E. Dahlberg, and U. Katy Nuclear export of microRNA precursors Science 303 2004 95 98
-
(2004)
Science
, vol.303
, pp. 95-98
-
-
Lund, E.1
Gottingen, S.2
Calando, A.3
Dahlberg, J.E.4
Katy, U.5
-
21
-
-
0141843656
-
The nuclear RNase III Drosha initiates microRNA processing
-
Y. Lee, C. Ahn, J. Han, H. Choi, J. Kim, and J. Yim The nuclear RNase III Drosha initiates microRNA processing Nature 425 2003 415 419
-
(2003)
Nature
, vol.425
, pp. 415-419
-
-
Lee, Y.1
Ahn, C.2
Han, J.3
Choi, H.4
Kim, J.5
Yim, J.6
-
22
-
-
0035800521
-
A cellular function for the RNA-interference enzyme dicer in the maturation of the let-7 small temporal RNA
-
G. Hutvagner, J. McLachlan, A.E. Pasquinelli, E. Balint, T. Tuschl, and P.D. Zamore A cellular function for the RNA-interference enzyme dicer in the maturation of the let-7 small temporal RNA Science 293 2001 834 838
-
(2001)
Science
, vol.293
, pp. 834-838
-
-
Hutvagner, G.1
McLachlan, J.2
Pasquinelli, A.E.3
Balint, E.4
Tuschl, T.5
Zamore, P.D.6
-
23
-
-
33746556993
-
A brief history of RNAi: The silence of the genes
-
G.L. Sen, and H.M. Blau A brief history of RNAi: the silence of the genes FASEB J 20 2006 1293 1299
-
(2006)
FASEB J
, vol.20
, pp. 1293-1299
-
-
Sen, G.L.1
Blau, H.M.2
-
24
-
-
0035942736
-
Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
-
S.M. Elbashir, J. Harborth, W. Lendeckel, A. Yalcin, K. Weber, and T. Tuschl Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells Nature 411 2001 494 498
-
(2001)
Nature
, vol.411
, pp. 494-498
-
-
Elbashir, S.M.1
Harborth, J.2
Lendeckel, W.3
Yalcin, A.4
Weber, K.5
Tuschl, T.6
-
25
-
-
1842816517
-
Distinct roles for drosophila dicer-1 and dicer-2 in the siRNA/miRNA silencing pathways
-
Y.S. Lee, K. Nakahara, J.W. Pham, K. Kim, Z. He, and E.J. Sontheimer Distinct roles for drosophila dicer-1 and dicer-2 in the siRNA/miRNA silencing pathways Cell 117 2004 69 81
-
(2004)
Cell
, vol.117
, pp. 69-81
-
-
Lee, Y.S.1
Nakahara, K.2
Pham, J.W.3
Kim, K.4
He, Z.5
Sontheimer, E.J.6
-
28
-
-
77956621869
-
Advances in synthetic siRNA delivery
-
N. Manjunath, and D.M. Dykxhoorn Advances in synthetic siRNA delivery Discov Med 9 2010 418 430
-
(2010)
Discov Med
, vol.9
, pp. 418-430
-
-
Manjunath, N.1
Dykxhoorn, D.M.2
-
29
-
-
51349151108
-
Effects of repetitive transcranial magnetic stimulation on adenosine triphosphate content and microtubule associated protein-2 expression after cerebral ischemia-reperfusion injury in rat brain
-
H.L. Feng, L. Yan, and L.Y. Cui Effects of repetitive transcranial magnetic stimulation on adenosine triphosphate content and microtubule associated protein-2 expression after cerebral ischemia-reperfusion injury in rat brain Chin Med J (Engl) 121 2008 1307 1312
-
(2008)
Chin Med J (Engl)
, vol.121
, pp. 1307-1312
-
-
Feng, H.L.1
Yan, L.2
Cui, L.Y.3
-
30
-
-
48849109369
-
Regulation of apoptotic and inflammatory cell signaling in cerebral ischemia: The complex roles of heat shock protein 70
-
R.G. Giffard, R.Q. Han, J.F. Emery, M. Duan, and J.F. Pittet Regulation of apoptotic and inflammatory cell signaling in cerebral ischemia: the complex roles of heat shock protein 70 Anesthesiology 109 2008 339 348
-
(2008)
Anesthesiology
, vol.109
, pp. 339-348
-
-
Giffard, R.G.1
Han, R.Q.2
Emery, J.F.3
Duan, M.4
Pittet, J.F.5
-
31
-
-
0031692291
-
Neuronal damage and plasticity identified by microtubule-associated protein 2, growth-associated protein 43, and cyclin d1 immunoreactivity after focal cerebral ischemia in rats
-
[discussion 1980-1971]
-
Y. Li, N. Jiang, C. Powers, and M. Chopp Neuronal damage and plasticity identified by microtubule-associated protein 2, growth-associated protein 43, and cyclin d1 immunoreactivity after focal cerebral ischemia in rats Stroke 29 1998 1972 1980 [discussion 1980-1971]
-
(1998)
Stroke
, vol.29
, pp. 1972-1980
-
-
Li, Y.1
Jiang, N.2
Powers, C.3
Chopp, M.4
-
32
-
-
33645108875
-
Thrombin/thrombin receptor (par-1)-mediated induction of il-8 and VEGF expression in prostate cancer cells
-
J. Liu, P. Schuff-Werner, and M. Steiner Thrombin/thrombin receptor (par-1)-mediated induction of il-8 and VEGF expression in prostate cancer cells Biochem Biophys Res Commun 343 2006 183 189
-
(2006)
Biochem Biophys Res Commun
, vol.343
, pp. 183-189
-
-
Liu, J.1
Schuff-Werner, P.2
Steiner, M.3
-
33
-
-
70349584089
-
Downregulation of protease activated receptor expression and cytokine production in p815 cells by RNA interference
-
L. Qiao, H. Zhang, S. Wu, and S. He Downregulation of protease activated receptor expression and cytokine production in p815 cells by RNA interference BMC Cell Biol 10 2009 62
-
(2009)
BMC Cell Biol
, vol.10
, pp. 62
-
-
Qiao, L.1
Zhang, H.2
Wu, S.3
He, S.4
-
34
-
-
55349098455
-
Targeting melanoma growth and metastasis with systemic delivery of liposome-incorporated protease-activated receptor-1 small interfering RNA
-
G.J. Villares, M. Zigler, H. Wang, V.O. Melnikova, H. Wu, and R. Friedman Targeting melanoma growth and metastasis with systemic delivery of liposome-incorporated protease-activated receptor-1 small interfering RNA Cancer Res 68 2008 9078 9086
-
(2008)
Cancer Res
, vol.68
, pp. 9078-9086
-
-
Villares, G.J.1
Zigler, M.2
Wang, H.3
Melnikova, V.O.4
Wu, H.5
Friedman, R.6
-
35
-
-
70350398248
-
Crosstalk between protease-activated receptor 1 and platelet-activating factor receptor regulates melanoma cell adhesion molecule (mcam/muc18) expression and melanoma metastasis
-
V.O. Melnikova, K. Balasubramanian, G.J. Villares, A.S. Dobroff, M. Zigler, and H. Wang Crosstalk between protease-activated receptor 1 and platelet-activating factor receptor regulates melanoma cell adhesion molecule (mcam/muc18) expression and melanoma metastasis J Biol Chem 284 2009 28845 28855
-
(2009)
J Biol Chem
, vol.284
, pp. 28845-28855
-
-
Melnikova, V.O.1
Balasubramanian, K.2
Villares, G.J.3
Dobroff, A.S.4
Zigler, M.5
Wang, H.6
-
36
-
-
7544240162
-
Double transfection improves small interfering RNA-induced thrombin receptor (par-1) gene silencing in du 145 prostate cancer cells
-
J. Liu, P. Schuff-Werner, and M. Steiner Double transfection improves small interfering RNA-induced thrombin receptor (par-1) gene silencing in du 145 prostate cancer cells FEBS Lett 577 2004 175 180
-
(2004)
FEBS Lett
, vol.577
, pp. 175-180
-
-
Liu, J.1
Schuff-Werner, P.2
Steiner, M.3
-
37
-
-
0004270170
-
-
Greene Pub. Associates; J. Wiley Brooklyn, N.Y. Media, Pa order fulfillment
-
Roger Brent, REK, J.G. Seidman, Kevin Struhl, Frederick M. Ausubel, and Virginia Benson Chanda Current protocols in molecular biology 2003 Greene Pub. Associates; J. Wiley Brooklyn, N.Y. Media, Pa order fulfillment
-
(2003)
Current Protocols in Molecular Biology
-
-
Brent, R.1
Rek2
Seidman, J.G.3
Struhl, K.4
Ausubel, F.M.5
Chanda, V.B.6
-
39
-
-
43849106645
-
SiRNAs with high specificity to the target: A systematic design by CRM algorithm
-
T. Alsheddi, L. Vasin, R. Meduri, M. Randhawa, G. Glazko, and A. Baranova siRNAs with high specificity to the target: a systematic design by CRM algorithm Mol Biol (Mosk) 42 2008 163 171
-
(2008)
Mol Biol (Mosk)
, vol.42
, pp. 163-171
-
-
Alsheddi, T.1
Vasin, L.2
Meduri, R.3
Randhawa, M.4
Glazko, G.5
Baranova, A.6
-
40
-
-
38449100230
-
A protocol for designing siRNAs with high functionality and specificity
-
A. Birmingham, E. Anderson, K. Sullivan, A. Reynolds, Q. Boese, and D. Leake A protocol for designing siRNAs with high functionality and specificity Nat Protoc 2 2007 2068 2078
-
(2007)
Nat Protoc
, vol.2
, pp. 2068-2078
-
-
Birmingham, A.1
Anderson, E.2
Sullivan, K.3
Reynolds, A.4
Boese, Q.5
Leake, D.6
-
41
-
-
33747799289
-
Enhancing and confirming the specificity of RNAi experiments
-
B.R. Cullen Enhancing and confirming the specificity of RNAi experiments Nat Methods 3 2006 677 681
-
(2006)
Nat Methods
, vol.3
, pp. 677-681
-
-
Cullen, B.R.1
-
42
-
-
44449149276
-
Analysis of siRNA specificity on targets with double-nucleotide mismatches
-
C. Dahlgren, H.Y. Zhang, Q. Du, M. Grain, G. Norstedt, and C. Wahlestedt Analysis of siRNA specificity on targets with double-nucleotide mismatches Nucleic Acids Res 36 2008 e53
-
(2008)
Nucleic Acids Res
, vol.36
, pp. 53
-
-
Dahlgren, C.1
Zhang, H.Y.2
Du, Q.3
Grain, M.4
Norstedt, G.5
Wahlestedt, C.6
-
43
-
-
3242889236
-
Sidirect: Highly effective, target-specific siRNA design software for mammalian RNA interference
-
Y. Naito, T. Yamada, K. Ui-Tei, S. Morishita, and K. Saigo Sidirect: highly effective, target-specific siRNA design software for mammalian RNA interference Nucleic Acids Res 32 2004 W124 W129
-
(2004)
Nucleic Acids Res
, vol.32
-
-
Naito, Y.1
Yamada, T.2
Ui-Tei, K.3
Morishita, S.4
Saigo, K.5
|