Prior use of antithrombotic agents and neurological functional outcome at discharge in patients with ischemic stroke

Journal of Thrombosis and Haemostasis

Volumn 4, Issue 9, 2006, Pages 1957-1961

  Paciaroni, Maurizio ^a   Agnelli, G ^a   Caso, V ^a   Venti, M ^a   Alberti, A ^a   Milia, P ^a   Silvestrelli, G ^a   Biagini, S ^a  

^a UNIVERSITY OF PERUGIA   (Italy)

Author keywords

Anticoagulants; Antiplatelet agents; Aspirin; Stroke

Indexed keywords

ACETYLSALICYLIC ACID; ANTICOAGULANT AGENT; ANTITHROMBOCYTIC AGENT; ANTIVITAMIN K; CLOPIDOGREL; HEPARIN; HEPARIN CALCIUM; LOW MOLECULAR WEIGHT HEPARIN; NADROPARIN; PLACEBO; TICLOPIDINE;

ADULT; AGED; ANTICOAGULANT THERAPY; ARTICLE; CEREBROVASCULAR ACCIDENT; CLINICAL TRIAL; CORRELATION ANALYSIS; DISEASE REGISTRY; DISEASE SEVERITY; DRUG DOSE REGIMEN; DRUG EFFECT; DRUG USE; DYSLIPIDEMIA; FEMALE; GENDER; HOSPITAL DISCHARGE; HUMAN; ITALY; MAJOR CLINICAL STUDY; MALE; META ANALYSIS; MORTALITY; NERVOUS SYSTEM FUNCTION; NEUROLOGIC EXAMINATION; OUTCOME ASSESSMENT; PRIORITY JOURNAL; RANKIN SCALE; SYSTEMATIC REVIEW;

AGED; AGED, 80 AND OVER; ANTICOAGULANTS; BRAIN ISCHEMIA; CEREBROVASCULAR ACCIDENT; FEMALE; FIBRINOLYTIC AGENTS; HUMANS; MALE; MIDDLE AGED; NERVOUS SYSTEM DISEASES; PLATELET AGGREGATION INHIBITORS; PREMEDICATION; STROKE; TREATMENT OUTCOME;

EID: 33747185837     PISSN: 15387933     EISSN: 15387836     Source Type: Journal    
DOI: 10.1111/j.1538-7836.2006.02095.x     Document Type: Article

References (34)

1. Lampl Y, Boaz M, Sadeh M. The significance of prestroke aspirin dosage in fatal outcome of acute stroke. Clin Neuropharmacol 2005; 28: 55-9.
2. Carolei A, Prencipe M, Fiorelli M, Fieschi C. Severity of stroke and aspirin. Neurology 1986; 36: 1010-1.
3. Grotta JC, Lemak NA, Gary H, Fields WS. Does platelet antiaggregant therapy lessen the severity of stroke ? Neurology 1985; 35: 632-6.
4. Kalra L, Perez I, Smithard DG, Sulch D. Does prior use of aspirin affect outcome in ischemic stroke ? Am J Med 2000; 108: 205-9.
5. Wilterdink JL, Bendixen B, Adams HP, Woolson RF, Clarke WR, Hansen MD. for the TOAST Investigators. Effect of prior aspirin use on stroke severity in the Trial of Org 10172 in Acute Stroke Treatment (TOAST). Stroke 2001; 32: 2836-40.
6. Hylek EM, Go AS, Chang Y, Jensvold NG, Henault LE, Selby JV, Singer DE. Effect of intensity of oral anticoagulation on stroke severity and mortality in atrial fibrillation. N Engl J Med 2003; 349: 1019-26.
7. De Keyser J, Harroelen L, De Klippel N. Early outcome in acute ischemic stroke is not influenced by the prophylactic use of low-dose aspirin. J Neurol Sci 1997; 145: 93-6.
8. Karepov V, Bornstein NM, Hass Y, Korczyn AD. Does daily aspirin diminish severity of first-ever stroke ? Arch Neurol 1997; 54: 1369-71.
9. Paciaroni M, Silvestrelli G, Caso V, Corea F, Venti M, Milia P, Tambasco N, Parnetti L, Gallai V. Neurovascular territories involved in different etiological subtype of ischemic stroke in the Perugia Stroke Registry. Eur J Neurol 2003; 10: 361-5.
10. Silvestrelli G, Corea F, Paciaroni M, Milia P, Palmerini F, Parnetti L, Gallai V. The Perugia hospital-based Stroke Registry: Report of the 2nd year. Clin Exp Hypertens 2002; 24: 485-91.
11. Adams HP, Bendixen BH, Kappelle LJ, Biller J, Love BB, Gordon DL, Marsh III EE. Classification of subtype of acute ischemic stroke: Definitions for use in a multicenter clinical trial. Stroke 1993; 24: 35-41.
12. De Haan R, Limburg M, Bossuyt P, Vander Maulen J, Aaronson N. The clinical meaning of Rankin 'handicap' grades after stroke. Stroke 1995; 26: 2027-30.
13. Der Simonian R, Laird N. Meta-analysis in clinical trials. Control Clin Trials 1986; 7: 177-88.
14. The Canadian Cooperative Study Group. A randomized trial of aspirin and sulfinpyrazone in threatened stroke. N Engl J Med 1978; 299: 53-9.
15. Sorensen PS, Pedersen H, Marquardsen J, Petersson H, Heltberg A, Simonsen N, Munck O, Andersen LA. Acetyl-salicylic acid in the prevention of stroke in patients with reversible cerebral ischemic attacks: A Danish cooperative study. Stroke 1983; 14: 15-22.
16. Joseph R, Han E, Tsering C, Grunfeld S, Welch KM. Platelet activity and stroke severity. J Neurol Sci 1992; 108: 1-6.
17. Kumar S, Savitz S, Schlaug G, Caplan L, Selim M. Antiplatelets, ACE inhibitors, and statins combination reduces stroke severity and tissue at risk. Neurology 2006; 66: 1153-8.
18. Greisenegger S, Tentschert S, Weber M, Ferrari J, Lang W, Lalouschek W. Prior theraphy with antiplatelets agents is not associated with outcome in patients with acute ischemic stroke/TIA. J Neurol 2006; 253: 648-52.
19. High-dose acetylsalicylic acid after cerebral infarction. A Swedish Cooperative Study. Stroke 1987; 18: 325-34.
20. Joseph R, D'Andrea G, Oster SB, Welch KMA. Whole blood platelet function in acute ischemic stroke: Importance of dense body secretion and effects of antithrombotic agents. Stroke 1989; 20: 38-44.
21. Chamorro A, Cervera A, Castillo J, Davalos A, Aponte JJ, Planas AM. Unfractionated heparin is associated with a lower rise of serum vascular cell adhesion molecule-1 in acute ischemic stroke patients. Neurosci Lett 2002; 328: 229-32.
22. Cervera A, Justicia C, Reverter JC, Planas AM, Chamorro A. Steady plasma concentration of unfractionated heparin reduces infarcts volume and prevents inflammatory damage after transient focal cerebral ischemia in the rat. J Neurosci Res 2004; 77: 565-72.
23. Grilli M, Pizzi M, Memo M, Spano PF. Neuroprotection by aspirin and sodium salicylate through blockade of NF- κ B activation. Science 1996; 274: 1383-5.
24. Riepe M, Phys D, Kasischke K, Raupach A. Acetylsalicylic acid increases the tolerance against hypoxic and chemical hypoxia. Stroke 1997; 28: 2006-11.
25. Hallenbeck JM, Furlow TW. Prostaglandins I2 and indomethacin prevent impairment of post-ischemic brain reperfusion in the dog. Stroke 1979; 10: 629-37.
26. Rosenblum WI, El-Sabban F. Platelet aggregation in the cerebral microcirculation; effect of aspirin and other agents. Circ Res 1977; 40: 320-8.
27. Kuhn W, Muller T, Buttner T, Gerlach M. Aspirin as a free radical scavenger: Consequences for therapy of cerebrovascular ischemia. Stroke 1995; 28: 1959-60.
28. Collet JP, Montalescot G, Blanchet B, Tanguy ML, Golmard JL, Choussat R, Beygui F, Payot L, Vignolles N, Metzger JP, Thomas D. Impact of prior or recent withdrawal of oral antiplatelet agents on acute coronary syndromes. Circulation 2004; 110: 2361-7.
29. Indredavik B, Rohweder G, Lydersen S. Frequency and effect of optimal anticoagulation before onset of ischemic stroke in patients with known atrial fibrillation. J Intern Med 2005; 258: 133-44.
30. Paciaroni M, Agnelli G, Caso V, Venti M, Milia P, Silvestrelli G, Parnetti L, Biagini S. Atrial fibrillation in patients with first-ever stroke: Frequency, antithrombotic treatment before the event and effect on clinical outcome. J Thromb Haemost 2005; 3: 1-6.
31. Hankey GJ, Eikelboom JM. Aspirin resistance. Lancet 2006; 367: 606-17.
32. Patrono C. Aspirin resistance: Definition, mechanism and clinical read-outs. J Thromb Haemost 2003; 1: 1710-3.
33. De Haan R, Horn J, Limburg M, Van Der Meulen J, Bossuyt P. A comparison of five stroke scales with measures of disability, handicap, and quality of life. Stroke 1993; 24: 1178-81.
34. Young FB, Lees KR, Weir CJ. Strengthening acute stroke trials through optimal use of disability end points. Stroke 2003; 34: 2676-80.