Mutant TDP-43 and FUS cause age-dependent paralysis and neurodegeneration in C. elegans

PLoS ONE

Volumn 7, Issue 2, 2012, Pages

  Vaccaro, Alexandra ^a,b,c   Tauffenberger, Arnaud ^a,b,c   Aggad, Dina ^a,b,c   Rouleau, Guy ^a,b,c   Drapeau, Pierre ^b,c   Parker, J Alex ^a,b,c  

^a CENTRE HOSPITALIER DE L UNIVERSITÉ DE MONTRÉAL   (Canada)

^b UNIVERSITY OF MONTREAL   (Canada)

^c UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID CARRIER; BINDING PROTEIN; PROTEIN FUS; TAR DNA BINDING PROTEIN; UNCLASSIFIED DRUG; 4 AMINOBUTYRIC ACID; DNA BINDING PROTEIN; MUTANT PROTEIN; PROTEIN TDP-43; RNA BINDING PROTEIN;

AGE; AMYOTROPHIC LATERAL SCLEROSIS; ARTICLE; CAENORHABDITIS ELEGANS; CONTROLLED STUDY; FRONTOTEMPORAL DEMENTIA; GABAERGIC SYSTEM; GABAERGIC TRANSMISSION; MOTONEURON; MUSCLE CELL; NERVE DEGENERATION; NONHUMAN; PARALYSIS; PHENOTYPE; PROTEIN EXPRESSION; PROTEIN FOLDING; TRANSGENICS; ULTRAVIOLET IRRADIATION; AGING; ANIMAL; CHEMISTRY; GENETICS; HUMAN; LONGEVITY; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; PROTEIN QUATERNARY STRUCTURE; SOLUBILITY; STAINING; SYNAPTIC TRANSMISSION; TRANSGENE; TRANSGENIC ANIMAL;

AGING; ANIMALS; ANIMALS, GENETICALLY MODIFIED; CAENORHABDITIS ELEGANS; DNA-BINDING PROTEINS; GAMMA-AMINOBUTYRIC ACID; HUMANS; LONGEVITY; MOTOR NEURONS; MUTANT PROTEINS; NERVE DEGENERATION; PARALYSIS; PHENOTYPE; PROTEIN STRUCTURE, QUATERNARY; RNA-BINDING PROTEIN FUS; SOLUBILITY; STAINING AND LABELING; SYNAPTIC TRANSMISSION; TRANSGENES;

EID: 84857410364     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0031321     Document Type: Article

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