Electronic microscopy evidence for mitochondria as targets for Cd/Se/Te-based quantum dot 705 toxicity in vivo

Kaohsiung Journal of Medical Sciences

Volumn 28, Issue 7 SUPPL., 2012, Pages

  Lin, Chia Hua ^a   Chang, Louis W ^a   Wei, Yau Huei ^b   Wu, Shi Bei ^b   Yang, Chung Shi ^a   Chang, Wan Hsuan ^a   Chen, Yu Ching ^a   Lin, Pin Pin ^a  

^a NATIONAL HEALTH RESEARCH INSTITUTES   (Taiwan)

^b NATIONAL YANG MING UNIVERSITY   (Taiwan)

Author keywords

Cadmium; Kidney; Mitochondria; Quantum Dot 705; Toxicity assessment

Indexed keywords

CADMIUM; QTRACKER 705; QUANTUM DOT; QUANTUM DOT 705; SELENIUM; TELLURIUM; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; CLINICAL EVALUATION; CONFERENCE PAPER; CONTROLLED STUDY; DRUG EFFECT; DRUG SAFETY; ELECTRON MICROSCOPY; HISTOPATHOLOGY; HYPERPLASIA; HYPERTROPHY; IN VIVO STUDY; KIDNEY FUNCTION; KIDNEY PROXIMAL TUBULE; MALE; MITOCHONDRIAL VOLUME; MITOCHONDRION; MITOCHONDRION SWELLING; MOUSE; NONHUMAN; SINGLE DRUG DOSE;

ANIMALS; BLOOD UREA NITROGEN; CADMIUM; CREATININE; EPITHELIAL CELLS; FLUORESCENT DYES; KIDNEY TUBULES, PROXIMAL; MALE; MICE; MICE, INBRED ICR; MICROSCOPY, ELECTRON, TRANSMISSION; MITOCHONDRIA; MITOCHONDRIAL SIZE; QUANTUM DOTS; SELENIUM; TELLURIUM;

EID: 84864594560     PISSN: 1607551X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.kjms.2012.05.011     Document Type: Conference Paper

References (37)

1. X. Michalet, F.F. Pinaud, L.A. Bentolila, J.M. Tsay, S. Doose, and J.J. Li Quantum dots for live cells, in vivo imaging, and diagnostics Science 307 2005 538 544 (Pubitemid 40165671)
2. R. Hardman A toxicologic review of quantum dots: toxicity depends on physicochemical and environmental factors Environ Health Perspect 114 2006 165 172 (Pubitemid 43193634)
3. T.S. Hauck, R.E. Anderson, H.C. Fischer, S. Newbigging, and W.C. Chan In vivo quantum-dot toxicity assessment Small 6 2010 138 144
4. T.C. King-Heiden, P.N. Wiecinski, A.N. Mangham, K.M. Metz, D. Nesbit, and J.A. Pedersen Quantum dot nanotoxicity assessment using the zebrafish embryo Environ Sci Technol 43 2009 1605 1611
5. C.H. Lin, M.H. Yang, L.W. Chang, C.S. Yang, H. Chang, and W.H. Chang Cd/Se/Te-based quantum dot 705 modulated redox homeostasis with hepatotoxicity in mice Nanotoxicology 5 2011 650 663
6. C.H. Lin, L.W. Chang, H. Chang, M.H. Yang, C.S. Yang, and W.H. Lai The chemical fate of the Cd/Se/Te-based quantum dot 705 in the biological system: toxicity implications Nanotechnology 20 2009 215101
7. P. Lin, J.W. Chen, W.H. Chang, J.P. Wu, L. Redding, and H. Chang Computational and structural toxicology of a nanoparticle, quantum dot 705, in mice Environ Sci Technol 42 2008 6264 6270
8. R.S. Yang, L.W. Chang, J.P. Wu, M.H. Tsai, H.J. Wang, and Y.C. Kuo Persistent tissue kinetics and redistribution of nanoparticles, quantum dot 705, in mice: ICP-MS quantitative assessment Environ Health Perspect 115 2007 1339 1343 (Pubitemid 47471259)
9. P. Lin, J.W. Chen, L.W. Chang, J.P. Wu, L. Redding, and H. Chang Computational and ultrastructural toxicology of a nanoparticle, Quantum Dot 705, in mice Environ Sci Technol 42 2008 6264 6270
10. K.B. Male, B. Lachance, S. Hrapovic, G. Sunahara, and J.H. Luong Assessment of cytotoxicity of quantum dots and gold nanoparticles using cell-based impedance spectroscopy Anal Chem 80 2008 5487 5493
11. G. Oberdorster, E. Oberdorster, and J. Oberdorster Nanotoxicology: an emerging discipline evolving from studies of ultrafine particles Environ Health Perspect 113 2005 823 839 (Pubitemid 40984181)
12. A.O. Choi, S.J. Cho, J. Desbarats, J. Lovric, and D. Maysinger Quantum dot-induced cell death involves Fas upregulation and lipid peroxidation in human neuroblastoma cells J Nanobiotechnology 5 2007 1
13. J. Lovric, S.J. Cho, F.M. Winnik, and D. Maysinger Unmodified cadmium telluride quantum dots induce reactive oxygen species formation leading to multiple organelle damage and cell death Chem Biol 12 2005 1227 1234 (Pubitemid 41628258)
14. S.J. Cho, D. Maysinger, M. Jain, B. Roder, S. Hackbarth, and F.M. Winnik Long-term exposure to CdTe quantum dots causes functional impairments in live cells Langmuir 23 2007 1974 1980 (Pubitemid 46406150)
15. W.H. Chan, N.H. Shiao, and P.Z. Lu CdSe quantum dots induce apoptosis in human neuroblastoma cells via mitochondrial-dependent pathways and inhibition of survival signals Toxicol Lett 167 2006 191 200
16. F. Thevenod Nephrotoxicity and the proximal tubule. Insights from cadmium Nephron Physiol 93 2003 87 93
17. A. Kukner, N. Colakoglu, H. Kara, H. Oner, C. Ozogul, and E. Ozan Ultrastructural changes in the kidney of rats with acute exposure to cadmium and effects of exogenous metallothionein Biol Trace Elem Res 119 2007 137 146 (Pubitemid 47585003)
18. K. Matsuura, M. Takasugi, Y. Kunifuji, A. Horie, and A. Kuroiwa Morphological effects of cadmium on proximal tubular cells in rats Biol Trace Elem Res 31 1991 171 182
19. J. Casademont, and O. Miro Electron transport chain defects in heart failure Heart Fail Rev 7 2002 131 139 (Pubitemid 34624801)
20. I. Nishino, O. Kobayashi, Y. Goto, M. Kurihara, K. Kumagai, and T. Fujita A new congenital muscular dystrophy with mitochondrial structural abnormalities Muscle Nerve 21 1998 40 47 (Pubitemid 28041679)
21. G. Siciliano, M. Mancuso, L. Pasquali, M.L. Manca, A. Tessa, and A. Iudice Abnormal levels of human mitochondrial transcription factor A in skeletal muscle in mitochondrial encephalomyopathies Neurol Sci 21 2000 S985 S987
22. H.C. Lee, P.H. Yin, C.Y. Lu, C.W. Chi, and Y.H. Wei Increase of mitochondria and mitochondrial DNA in response to oxidative stress in human cells Biochem J 348 Pt 2 2000 425 432
23. H.C. Lee, and Y.H. Wei Mitochondrial biogenesis and mitochondrial DNA maintenance of mammalian cells under oxidative stress Int J Biochem Cell Biol 37 2005 822 834
24. A. Nel, T. Xia, L. Madler, and N. Li Toxic potential of materials at the nanolevel Science 311 2006 622 627 (Pubitemid 43191298)
25. J.M. Tsay, and X. Michalet New light on quantum dot cytotoxicity Chem Biol 12 2005 1159 1161 (Pubitemid 41628250)
26. S. Bai, and Z. Xu Effects of cadmium on mitochondrion structure and energy metabolism of Palteobagrus fulvidraco gill Ying Yong Sheng Tai Xue Bao 17 2006 1213 1217 (Pubitemid 44637440)
27. W.Y. Chan, and O.M. Rennert Cadmium nephropathy Ann Clin Lab Sci 11 1981 229 238 (Pubitemid 11102773)
28. H. Savolainen Cadmium-associated renal disease Ren Fail 17 1995 483 487
29. R.C. Srivastava, R. Srivastava, T.N. Srivastava, and S.P. Jain Effect of organo-tellurium compounds on the enzymatic alterations in rats Toxicol Lett 16 1983 311 316 (Pubitemid 13121336)
30. A. Taylor Biochemistry of tellurium Biol Trace Elem Res 55 1996 231 239 (Pubitemid 27152807)
31. F.C. Meotti, V.C. Borges, G. Zeni, J.B. Rocha, and C.W. Nogueira Potential renal and hepatic toxicity of diphenyl diselenide, diphenyl ditelluride and Ebselen for rats and mice Toxicol Lett 143 2003 9 16 (Pubitemid 36412167)
32. E.A. Belyaeva, D. Dymkowska, M.R. Wieckowski, and L. Wojtczak Mitochondria as an important target in heavy metal toxicity in rat hepatoma AS-30D cells Toxicol Appl Pharmacol 231 2008 34 42
33. X.P. Huang, P.J. O'Brien, and D.M. Templeton Mitochondrial involvement in genetically determined transition metal toxicity I. Iron toxicity Chem Biol Interact 163 2006 68 76 (Pubitemid 44572215)
34. R. Mehta, D.M. Templeton, and P.J. O'Brien Mitochondrial involvement in genetically determined transition metal toxicity II. Copper toxicity Chem Biol Interact 163 2006 77 85 (Pubitemid 44572217)
35. V. Kumar, A. Bal, and K.D. Gill Susceptibility of mitochondrial superoxide dismutase to aluminium induced oxidative damage Toxicology 255 2009 117 123
36. M.A. Peraza, D.W. Cromey, B. Carolus, D.E. Carter, and A.J. Gandolfi Morphological and functional alterations in human proximal tubular cell line induced by low level inorganic arsenic: evidence for targeting of mitochondria and initiated apoptosis J Appl Toxicol 26 2006 356 367 (Pubitemid 44064935)
37. G. Krumschnabel, C. Manzl, C. Berger, and B. Hofer Oxidative stress, mitochondrial permeability transition, and cell death in Cu-exposed trout hepatocytes Toxicol Appl Pharmacol 209 2005 62 73 (Pubitemid 41547218)