A cytotoxic type III secretion effector of vibrio parahaemolyticus targets vacuolar H+-ATPase subunit C and ruptures host cell lysosomes

PLoS Pathogens

Volumn 8, Issue 7, 2012, Pages 27-

  Matsuda, Shigeaki ^a   Okada, Natsumi ^a,b   Kodama, Toshio ^a   Honda, Takeshi ^a   Iida, Tetsuya ^a  

^a OSAKA UNIVERSITY   (Japan)

^b KYOTO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE; BACTERIAL PROTEIN; CATHEPSIN D; UNCLASSIFIED DRUG; VEPA PROTEIN; ATP6V0C PROTEIN, HUMAN; CUP5 PROTEIN, S CEREVISIAE; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE; SACCHAROMYCES CEREVISIAE PROTEIN; SMALL INTERFERING RNA; VIRULENCE FACTOR;

ARTICLE; CELL DEATH; CYTOLYSIS; CYTOSOL; CYTOTOXICITY; FEMALE; FUNGAL GENE; FUNGUS GROWTH; GENE SILENCING; GENETIC ANALYSIS; GENETIC TRANSFECTION; GROWTH INHIBITION; HELA CELL; HUMAN; HUMAN CELL; LYSOSOME; NONHUMAN; SACCHAROMYCES CEREVISIAE; TYPE III SECRETION SYSTEM; VIBRIO PARAHAEMOLYTICUS; APOPTOSIS; BACTERIAL SECRETION SYSTEM; BIOSYNTHESIS; GENETICS; MACROPHAGE; METABOLISM; PATHOGENICITY; RNA INTERFERENCE; SECRETION (PROCESS); TUMOR CELL LINE;

BACTERIA (MICROORGANISMS); MAMMALIA; SACCHAROMYCES CEREVISIAE; VIBRIO PARAHAEMOLYTICUS;

APOPTOSIS; BACTERIAL PROTEINS; BACTERIAL SECRETION SYSTEMS; CATHEPSIN D; CELL LINE, TUMOR; HELA CELLS; HUMANS; LYSOSOMES; MACROPHAGES; RNA INTERFERENCE; RNA, SMALL INTERFERING; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; VACUOLAR PROTON-TRANSLOCATING ATPASES; VIBRIO PARAHAEMOLYTICUS; VIRULENCE FACTORS;

EID: 84864582924     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1002803     Document Type: Article

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