Mechanism of intermolecular interactions of microsomal cytochrome P450s CYP17 and CYP21 involved in steroid hormone biosynthesis

Biochemistry (Moscow)

Volumn 77, Issue 6, 2012, Pages 585-592

  Sushko, T A ^a   Gilep, A A ^a   Usanov, S A ^a  

^a INSTITUTE OF BIOORGANIC CHEMISTRY   (Belarus)

Author keywords

CYP17; CYP21; Cytochrome P450; Protein protein interaction; Steroid hormone biosynthesis

Indexed keywords

CORTICOSTEROID; CYTOCHROME P450; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE FERRIHEMOPROTEIN REDUCTASE; STEROID 17ALPHA MONOOXYGENASE; STEROID 21 MONOOXYGENASE;

ADRENAL CORTEX; ARTICLE; BIOSYNTHESIS; CULTURE TECHNIQUE; ENDOPLASMIC RETICULUM; ENZYME SPECIFICITY; ENZYMOLOGY; ESCHERICHIA COLI; HUMAN; METABOLISM; OXIDATION REDUCTION REACTION; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN CONFORMATION;

ADRENAL CORTEX; ADRENAL CORTEX HORMONES; CELL CULTURE TECHNIQUES; CYTOCHROME P-450 ENZYME SYSTEM; ENDOPLASMIC RETICULUM; ESCHERICHIA COLI; HUMANS; NADPH-FERRIHEMOPROTEIN REDUCTASE; OXIDATION-REDUCTION; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN INTERACTION MAPPING; STEROID 17-ALPHA-HYDROXYLASE; STEROID 21-HYDROXYLASE; SUBSTRATE SPECIFICITY;

EID: 84864572315     PISSN: 00062979     EISSN: 16083040     Source Type: Journal    
DOI: 10.1134/S0006297912060041     Document Type: Article

References (37)

1. Forest, M. G. (2004) Hum. Reprod. Update, 10, 469-485.
2. Yanase, T. (1995) J. Steroid Biochem. Mol. Biol., 53, 153-157.
3. Hall, P. F. (1991) J. Steroid Biochem. Mol. Biol., 40, 527-532.
4. Kominami, S., Ochi, H., Kobayashi, Y., and Takemori, S. (1980) J. Biol. Chem., 255, 3386-3394.
5. Dufau, M. L., Minegishi, T., Buczko, E., Kitamura, M., Delgado, C., and Namiki, M. (1989) Ann. N. Y. Acad. Sci., 564, 57-76.
6. Zhang, L. H., Rodriguez, H., Ohno, S., and Miller, W. L. (1995) Proc. Natl. Acad. Sci. USA, 92, 10619-10623.
7. Miller, W. L. (2005) Endocrinology, 146, 2544-2550.
8. Miwa, G. T., West, S. B., Huang, M. T., and Lu, A. Y. (1979) J. Biol. Chem., 254, 5695-5700.
9. Estabrook, R. W., Franklin, M. R., Cohen, B., Shigamatzu, A., and Hildebrandt, A. G. (1971) Metabolism, 20, 187-199.
10. Yanagibashi, K., and Hall, P. F. (1986) J. Biol. Chem., 261, 8429-8433.
11. Onoda, M., and Hall, P. F. (1982) Biochem. Biophys. Res. Commun., 108, 454-460.
12. Hlavica, P., Schulze, J., and Lewis, D. F. (2003) J. Inorg. Biochem., 96, 279-297.
13. Ogishima, T., Kinoshita, J. Y., Mitani, F., Suematsu, M., and Ito, A. (2003) J. Biol. Chem., 278, 21204-21211.
14. Min, L., Strushkevich, N. V., Harnastai, I. N., Iwamoto, H., Gilep, A. A., Takemori, H., Usanov, S. A., Nonaka, Y., Hori, H., Vinson, G. P., and Okamoto, M. (2005) FEBS J., 272, 5832-5843.
15. Conley, A. J., and Bird, I. M. (1997) Biol. Reprod., 56, 789-799.
16. Nishihara, K., Kanemori, M., Kitagawa, M., Yanagi, H., and Yura, T. (1998) Appl. Environ. Microbiol., 64, 1694-1699.
17. Harnastai, I. N., Gilep, A. A., and Usanov, S. A. (2006) Protein Expr. Purif., 46, 47-55.
18. Gilep, A. A., Guryev, O. L., Usanov, S. A., and Estabrook, R. W. (2001) Biochem. Biophys. Res. Commun., 284, 937-941.
19. Omura, T., and Sato, R. (1964) J. Biol. Chem., 239, 2370-2378.
20. Porter, T. D., Wilson, T. E., and Kasper, C. B. (1987) Arch. Biochem. Biophys., 254, 353-367.
21. Rehman, K. S., Carr, B. R., and Rainey, W. E. (2003) J. Soc. Gynecol. Investig., 10, 372-380.
22. Pechurskaya, T. A., Lukashevich, O. P., Gilep, A. A., and Usanov, S. A. (2008) Biochemistry (Moscow), 73, 806-811.
23. Shimada, T., Misono, K. S., and Guengerich, F. P. (1986) J. Biol. Chem., 261, 909-921.
24. Gardiner, S. J., and Begg, E. J. (2006) Pharmacol. Rev., 58, 521-590.
25. Backes, W. L., and Kelley, R. W. (2003) Pharmacol. Ther., 98, 221-233.
26. Backes, W. L., Batie, C. J., and Cawley, G. F. (1998) Biochemistry, 37, 12852-12859.
27. Hazai, E., and Kupfer, D. (2005) Drug metab. Dispos., 33, 157-164.
28. Tan, Y., Patten, C. J., Smith, T., and Yang, C. S. (1997) Arch. Biochem. Biophys., 342, 82-91.
29. Kelley, R. W., Cheng, D., and Backes, W. L. (2006) Biochemistry, 45, 15807-15816.
30. Yamazaki, H., Gillam, E. M., Dong, M. S., Johnson, W. W., Guengerich, F. P., and Shimada, T. (1997) Arch. Biochem. Biophys., 342, 329-337.
31. Subramanian, M., Low, M., Locuson, C. W., and Tracy, T. S. (2009) Drug Metab. Dispos., 37, 1682-1689.
32. Zhao, B., Lei, L., Kagawa, N., Sundaramoorthy, M., Banerjee, S., Nagy, L. D., Guengerich, F. P., and Waterman, M. R. (2012) J. Biol. Chem., 287, 10613-10622.
33. Nikfarjam, L., Izumi, S., Yamazak, T., and Kominam, S. (2006) Biochim. Biophys. Acta, 1764, 1126-1131.
34. Auchus, R. J., and Miller, W. L. (1999) Mol. Endocrinol., 13, 1169-1182.
35. Im, S. C., and Waskell, L. (2011) Arch. Biochem. Biophys., 507, 144-153.
36. Robins, T., Carlsson, J., Sunnerhagen, M., Wedell A., and Persson, B. (2006) Mol. Endocrinol., 20, 2946-2964.
37. Miller, W. L., Auchus, R. J., and Geller, D. H. (1997) Steroids, 62, 133-142.