Targeted deletion of Kcne2 impairs HCN channel function in mouse thalamocortical circuits

PLoS ONE

Volumn 7, Issue 8, 2012, Pages

  Ying, Shui Wang ^a   Kanda, Vikram A ^a   Hu, Zhaoyang ^b   Purtell, Kerry ^a   King, Elizabeth C ^a   Abbott, Geoffrey W ^b   Goldstein, Peter A ^a  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOPYRIDINE; CYCLIC NUCLEOTIDE GATED CHANNEL; HYPERPOLARIZATION ACTIVATED CYCLIC NUCLEOTIDE GATED CHANNEL; HYPERPOLARIZATION ACTIVATED CYCLIC NUCLEOTIDE GATED CHANNEL 1; HYPERPOLARIZATION ACTIVATED CYCLIC NUCLEOTIDE GATED CHANNEL 2; HYPERPOLARIZATION ACTIVATED CYCLIC NUCLEOTIDE GATED CHANNEL 4; POTASSIUM CHANNEL KCNE2; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BRAIN SLICE; CHANNEL GATING; CONTROLLED STUDY; EXCITATORY POSTSYNAPTIC POTENTIAL; FEMALE; GENE DELETION; HYPERPOLARIZATION; KCNE2 GENE; MALE; MOUSE; NERVE CELL EXCITABILITY; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PYRAMIDAL NERVE CELL; TEMPORAL SUMMATION; THALAMOCORTICAL TRACT; THALAMUS;

4-AMINOPYRIDINE; ANIMALS; CEREBRAL CORTEX; CYCLIC NUCLEOTIDE-GATED CATION CHANNELS; DOWN-REGULATION; FEMALE; GENE DELETION; GENE TARGETING; GLUTAMATES; ION CHANNEL GATING; ION CHANNELS; MALE; MICE; MICE, INBRED C57BL; NERVE NET; NEURONS; POTASSIUM CHANNELS; POTASSIUM CHANNELS, VOLTAGE-GATED; PYRAMIDAL CELLS; PYRIMIDINES; SOMATOSENSORY CORTEX; THALAMUS;

MUS;

EID: 84864557388     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0042756     Document Type: Article

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