-
1
-
-
0023872949
-
Pancreatic cancer: The greatest oncological challenge
-
Williamson RC: Pancreatic cancer: the greatest oncological challenge. Br Med J 13: 445-446, 1988.
-
(1988)
Br Med J
, vol.13
, pp. 445-446
-
-
Williamson, R.C.1
-
2
-
-
0021633807
-
Epidemiology of pancreatic cancer
-
Gordis L and Gold EB: Epidemiology of pancreatic cancer. World J Surg 8: 808-821, 1984.
-
(1984)
World J Surg
, vol.8
, pp. 808-821
-
-
Gordis, L.1
Gold, E.B.2
-
3
-
-
0030049697
-
Phase II study of gemcitabine in patients with advanced pancreatic cancer
-
Carmichael J, Fink U, Russell RC, Spittle MF, Harris AL, Spiessi G and Blatter J: Phase II study of gemcitabine in patients with advanced pancreatic cancer. Br J Cancer 73: 1-5, 1996.
-
(1996)
Br J Cancer
, vol.73
, pp. 1-5
-
-
Carmichael, J.1
Fink, U.2
Russell, R.C.3
Spittle, M.F.4
Harris, A.L.5
Spiessi, G.6
Blatter, J.7
-
4
-
-
69249144061
-
A proteomic profiling of gemcitabine resistance in pancreatic cancer cell lines
-
Mori-Iwamoto S, Kuramitsu Y, Ryozawa S, Taba K, Fujimoto M, Okita K, Nakamura K and Sakaida I: A proteomic profiling of gemcitabine resistance in pancreatic cancer cell lines. Mol Med Rep 1: 429-434, 2008.
-
(2008)
Mol Med Rep
, vol.1
, pp. 429-434
-
-
Mori-Iwamoto, S.1
Kuramitsu, Y.2
Ryozawa, S.3
Taba, K.4
Fujimoto, M.5
Okita, K.6
Nakamura, K.7
Sakaida, I.8
-
5
-
-
77958581453
-
Identification of up- and down-regulated proteins in gemcitabine- resistant pancreatic cancer cells using two-dimensional gel electrophoresis and mass spectrometry
-
Kuramitsu Y, Taba K, Ryozawa S, Yoshida K, Tanaka T, Zhang X, Maehara S, Maehara Y, Sakaida I and Nakamura K: Identification of up- and down-regulated proteins in gemcitabine-resistant pancreatic cancer cells using two-dimensional gel electrophoresis and mass spectrometry. Anticancer Res 30: 3367-3372, 2010.
-
(2010)
Anticancer Res
, vol.30
, pp. 3367-3372
-
-
Kuramitsu, Y.1
Taba, K.2
Ryozawa, S.3
Yoshida, K.4
Tanaka, T.5
Zhang, X.6
Maehara, S.7
Maehara, Y.8
Sakaida, I.9
Nakamura, K.10
-
6
-
-
65349170081
-
Interferon-γ down-regulates HSP27 of pancreatic cancer cells, and helps the cytotoxic effect of gemcitabine
-
Mori-Iwamoto S, Taba K, Kuramitsu Y, Ryozawa S, Tanaka T, Maehara S, Maehara Y, Okita K, Nakamura K and Sakaida I: Interferon-γ down-regulates HSP27 of pancreatic cancer cells, and helps the cytotoxic effect of gemcitabine. Pancreas 38: 224-226, 2009.
-
(2009)
Pancreas
, vol.38
, pp. 224-226
-
-
Mori-Iwamoto, S.1
Taba, K.2
Kuramitsu, Y.3
Ryozawa, S.4
Tanaka, T.5
Maehara, S.6
Maehara, Y.7
Okita, K.8
Nakamura, K.9
Sakaida, I.10
-
7
-
-
78649515098
-
KNK-437 down-regulates HSP27 of pancreatic cancer cells, and helps the cytotoxic effect of gemcitabine
-
Taba K, Kuramitsu Y, Ryozawa S, Yoshida K, Tanaka T, Mori-Iwamoto S, Maehara S, Maehara Y, Sakaida I and Nakamura K: KNK-437 down-regulates HSP27 of pancreatic cancer cells, and helps the cytotoxic effect of gemcitabine. Chemotherapy 57: 12-16, 2011.
-
(2011)
Chemotherapy
, vol.57
, pp. 12-16
-
-
Taba, K.1
Kuramitsu, Y.2
Ryozawa, S.3
Yoshida, K.4
Tanaka, T.5
Mori-Iwamoto, S.6
Maehara, S.7
Maehara, Y.8
Sakaida, I.9
Nakamura, K.10
-
8
-
-
77955832992
-
Heat-shock protein 27 is phosphorylated in gemcitabine-resistant pancreatic cancer cells
-
Taba K, Kuramitsu Y, Ryozawa S, Yoshida K, Tanaka T, Maehara S, Maehara Y, Sakaida I and Nakamura K: Heat-shock protein 27 is phosphorylated in gemcitabine-resistant pancreatic cancer cells. Anticancer Res 30: 2539-2543, 2010.
-
(2010)
Anticancer Res
, vol.30
, pp. 2539-2543
-
-
Taba, K.1
Kuramitsu, Y.2
Ryozawa, S.3
Yoshida, K.4
Tanaka, T.5
Maehara, S.6
Maehara, Y.7
Sakaida, I.8
Nakamura, K.9
-
9
-
-
0032722324
-
HSP27 inhibits cytochrome c-dependent activation of procaspase-9
-
Garrido C, Bruey JM, Fromentin A, Hammann A, Arrigo AP and Solary E: HSP27 inhibits cytochrome c-dependent activation of procaspase-9. FASEB J 13: 2061-2070, 1999.
-
(1999)
FASEB J
, vol.13
, pp. 2061-2070
-
-
Garrido, C.1
Bruey, J.M.2
Fromentin, A.3
Hammann, A.4
Arrigo, A.P.5
Solary, E.6
-
10
-
-
0032747966
-
HSP27 overexpression inhibits doxorubicin-induced apoptosis in human breast cancer cells
-
Hansen RK, Parra I, Lemieux P, Oesterreich S, Hilsenbeck SG and Fuqua SA: HSP27 overexpression inhibits doxorubicin-induced apoptosis in human breast cancer cells. Breast Cancer Res Treat 56: 187-196, 1999.
-
(1999)
Breast Cancer Res Treat
, vol.56
, pp. 187-196
-
-
Hansen, R.K.1
Parra, I.2
Lemieux, P.3
Oesterreich, S.4
Hilsenbeck, S.G.5
Fuqua, S.A.6
-
11
-
-
0029882949
-
Effect of overexpression of the small heat-shock protein HSP27 on the heat and drug sensitivities of human testis tumor cells
-
Richards EH, Hickey E, Weber L and Master JR: Effect of overexpression of the small heat-shock protein HSP27 on the heat and drug sensitivities of human testis tumor cells. Cancer Res 56: 2446-2451, 1996.
-
(1996)
Cancer Res
, vol.56
, pp. 2446-2451
-
-
Richards, E.H.1
Hickey, E.2
Weber, L.3
Master, J.R.4
-
13
-
-
34248176724
-
Heat-shock genes-integrating cell survival and death
-
Arya R, Mallik M and Lakhotia SC: Heat-shock genes-integrating cell survival and death. J Biosci 32: 595-610, 2007.
-
(2007)
J Biosci
, vol.32
, pp. 595-610
-
-
Arya, R.1
Mallik, M.2
Lakhotia, S.C.3
-
14
-
-
78649669332
-
Hsp27 protects adenocarcinoma cells from UV-induced apoptosis by Akt and p21-dependent pathways of survival
-
Kanagasabai R, Karthikeyan K, Vedam K, Qien W, Zhu Q and Ilangovan G: Hsp27 protects adenocarcinoma cells from UV-induced apoptosis by Akt and p21-dependent pathways of survival. Mol Cancer Res 8: 1399-1412, 2010.
-
(2010)
Mol Cancer Res
, vol.8
, pp. 1399-1412
-
-
Kanagasabai, R.1
Karthikeyan, K.2
Vedam, K.3
Qien, W.4
Zhu, Q.5
Ilangovan, G.6
-
15
-
-
33845232858
-
TNF-α decreases HSP27 in human blood mononuclear cells: Involvement of protein kinase c
-
Niwa M, Hotta K, Hara A, Hirade K, Ito H, Kato K and Kozawa O: TNF-α decreases HSP27 in human blood mononuclear cells: involvement of protein kinase c. Life Sci 80: 181-186, 2006.
-
(2006)
Life Sci
, vol.80
, pp. 181-186
-
-
Niwa, M.1
Hotta, K.2
Hara, A.3
Hirade, K.4
Ito, H.5
Kato, K.6
Kozawa, O.7
-
16
-
-
0038297011
-
Interferon-γ down-regulates Hsp27 expression and suppresses the negative regulation of cell death in oral squamous cell carcinoma lines
-
Yonekura N, Yokota S, Yonekura K, Dehari H, Arata S, Kohama G and Fujii N: Interferon-γ down-regulates Hsp27 expression and suppresses the negative regulation of cell death in oral squamous cell carcinoma lines. Cell Death Differ 10: 313-322, 2003.
-
(2003)
Cell Death Differ
, vol.10
, pp. 313-322
-
-
Yonekura, N.1
Yokota, S.2
Yonekura, K.3
Dehari, H.4
Arata, S.5
Kohama, G.6
Fujii, N.7
-
17
-
-
0036890112
-
Quercetin, apoptosis, heat shock
-
Jakubowicz-Gil J, Rzymowska J and Gawron A: Quercetin, apoptosis, heat shock. Biochem Pharmacol 64: 1591-1595, 2002.
-
(2002)
Biochem Pharmacol
, vol.64
, pp. 1591-1595
-
-
Jakubowicz-Gil, J.1
Rzymowska, J.2
Gawron, A.3
-
18
-
-
77649169304
-
Functional proteomic and structural insights into molecular targets related to the growth inhibitory effect of tanshinone IIA on HeLa cells
-
Pan TL, Hung YC, Wang PW, Chen ST, Hsu TK, Sintupisut N, Cheng CS and Lyu PC: Functional proteomic and structural insights into molecular targets related to the growth inhibitory effect of tanshinone IIA on HeLa cells. Proteomics 10: 914-929, 2010.
-
(2010)
Proteomics
, vol.10
, pp. 914-929
-
-
Pan, T.L.1
Hung, Y.C.2
Wang, P.W.3
Chen, S.T.4
Hsu, T.K.5
Sintupisut, N.6
Cheng, C.S.7
Lyu, P.C.8
-
19
-
-
33646900838
-
Triptolide, an inhibitor of the human heat-shock response that enhances stress-induced cell death
-
Westerheide SD, Kawahara TL, Orton K and Morimoto RI: Triptolide, an inhibitor of the human heat-shock response that enhances stress-induced cell death. J Biol Chem 281: 9616-9622, 2006.
-
(2006)
J Biol Chem
, vol.281
, pp. 9616-9622
-
-
Westerheide, S.D.1
Kawahara, T.L.2
Orton, K.3
Morimoto, R.I.4
-
20
-
-
29244479188
-
Blocking tumor cell migration and invasion with biphenyl isoxazole derivative KRIBB3, a synthetic molecule that inhibits Hsp27 phosphorylation
-
Shin KD, Lee MY, Shin DS, Lee S, Son KH, Koh S, Paik YK, Kwon BM and Han DC: Blocking tumor cell migration and invasion with biphenyl isoxazole derivative KRIBB3, a synthetic molecule that inhibits Hsp27 phosphorylation. J Biol Chem 280: 41439-41448, 2005.
-
(2005)
J Biol Chem
, vol.280
, pp. 41439-41448
-
-
Shin, K.D.1
Lee, M.Y.2
Shin, D.S.3
Lee, S.4
Son, K.H.5
Koh, S.6
Paik, Y.K.7
Kwon, B.M.8
Han, D.C.9
-
21
-
-
76649143731
-
Heat shock protein 27 is overexpressed in tumor tissues and increased in sera of patients with gastric adenocarcinoma
-
Huang Q, Ye J, Huang Q, Chen W, Wang L, Lin W, Lin J and Lin X: Heat shock protein 27 is overexpressed in tumor tissues and increased in sera of patients with gastric adenocarcinoma. Clin Chem Lab Med 48: 263-269, 2010.
-
(2010)
Clin Chem Lab Med
, vol.48
, pp. 263-269
-
-
Huang, Q.1
Ye, J.2
Huang, Q.3
Chen, W.4
Wang, L.5
Lin, W.6
Lin, J.7
Lin, X.8
-
22
-
-
77953454825
-
Identification of potential therapeutic targets in human head and neck squamous cell carcinoma
-
Han J, Kioi M, Chu WS, Kasperbauer JL, Strome SE and Puri RK: Identification of potential therapeutic targets in human head and neck squamous cell carcinoma. Head Neck Oncol 1: 27-35, 2009.
-
(2009)
Head Neck Oncol
, vol.1
, pp. 27-35
-
-
Han, J.1
Kioi, M.2
Chu, W.S.3
Kasperbauer, J.L.4
Strome, S.E.5
Puri, R.K.6
-
23
-
-
70049090562
-
Expression of potential molecular markers in renal cell carcinoma: Impact on clinicopathological outcomes in patients undergoing radical nephrectomy
-
Sakai I, Miyake H, Takenawa A and Fujisawa M: Expression of potential molecular markers in renal cell carcinoma: impact on clinicopathological outcomes in patients undergoing radical nephrectomy. BJU Int 104: 942-946, 2009.
-
(2009)
BJU Int
, vol.104
, pp. 942-946
-
-
Sakai, I.1
Miyake, H.2
Takenawa, A.3
Fujisawa, M.4
-
24
-
-
53749093700
-
Heat-shock proteins 27, 60 and 70 as prognostic markers of prostate cancer
-
Glaessgen A, Jonmarker S, Lindberg A, Nilsson B, Lewensohn R, Ekman P, Valdman A and Egevad L: Heat-shock proteins 27, 60 and 70 as prognostic markers of prostate cancer. APMIS 116: 888-895, 2008.
-
(2008)
APMIS
, vol.116
, pp. 888-895
-
-
Glaessgen, A.1
Jonmarker, S.2
Lindberg, A.3
Nilsson, B.4
Lewensohn, R.5
Ekman, P.6
Valdman, A.7
Egevad, L.8
-
25
-
-
28644438067
-
Proteomic analysis on metastasis-associated proteins of human hepatocellular carcinoma tissues
-
Song HY, Liu YK, Feng JT, Cui JF, Dai Z, Zhang LJ, Feng JX, Shen HL and Tang ZY: Proteomic analysis on metastasis-associated proteins of human hepatocellular carcinoma tissues. J Cancer Res Clin Oncol 132: 92-98, 2006.
-
(2006)
J Cancer Res Clin Oncol
, vol.132
, pp. 92-98
-
-
Song, H.Y.1
Liu, Y.K.2
Feng, J.T.3
Cui, J.F.4
Dai, Z.5
Zhang, L.J.6
Feng, J.X.7
Shen, H.L.8
Tang, Z.Y.9
-
26
-
-
0036556698
-
Overexpression of HSP27 affects the metastatic phenotype of human melanoma cells in vitro
-
Aldrian S, Trautinger F, Fröhlich I, Berger W, Micksche M and Kindas-Mügge I: Overexpression of HSP27 affects the metastatic phenotype of human melanoma cells in vitro. Cell Stress Chaperones 7: 177-185, 2002.
-
(2002)
Cell Stress Chaperones
, vol.7
, pp. 177-185
-
-
Aldrian, S.1
Trautinger, F.2
Fröhlich, I.3
Berger, W.4
Micksche, M.5
Kindas-Mügge, I.6
-
27
-
-
33646859435
-
MAPKAPK2 and HSP27 are downstream effectors of p38 MAP kinase-mediated matrix metalloproteinase type 2 activation and cell invasion in human prostate cancer
-
Xu L, Chen S and Bergan RC: MAPKAPK2 and HSP27 are downstream effectors of p38 MAP kinase-mediated matrix metalloproteinase type 2 activation and cell invasion in human prostate cancer. Oncogene 25: 2987-2998, 2006.
-
(2006)
Oncogene
, vol.25
, pp. 2987-2998
-
-
Xu, L.1
Chen, S.2
Bergan, R.C.3
-
28
-
-
4644237335
-
Heat shock protein 27 increases after androgen ablation and plays a cytoprotective role in hormone-refractory prostate cancer
-
Rocchi P, So A, Kojima S, Signaevsky M, Beraldi E, Fazli L, Hurtado-Coll A, Yamanaka K and Gleave M: Heat shock protein 27 increases after androgen ablation and plays a cytoprotective role in hormone-refractory prostate cancer. Cancer Res 64: 6595-6602, 2004.
-
(2004)
Cancer Res
, vol.64
, pp. 6595-6602
-
-
Rocchi, P.1
So, A.2
Kojima, S.3
Signaevsky, M.4
Beraldi, E.5
Fazli, L.6
Hurtado-Coll, A.7
Yamanaka, K.8
Gleave, M.9
-
29
-
-
80054814409
-
Hsp27 participates in the maintenance of breast cancer stem cells through regulation of epithelial-mesenchymal transition and nuclear factor-κB
-
Wei L, Liu TT, Wang HH, Hong HM, Yu AL, Feng HP and Chang WW: Hsp27 participates in the maintenance of breast cancer stem cells through regulation of epithelial-mesenchymal transition and nuclear factor-κB. Breast Cancer Res 13: R101, 2011.
-
(2011)
Breast Cancer Res
, vol.13
-
-
Wei, L.1
Liu, T.T.2
Wang, H.H.3
Hong, H.M.4
Yu, A.L.5
Feng, H.P.6
Chang, W.W.7
|