Heat shock protein 27 is over-expressed in tumor tissues and increased in sera of patients with gastric adenocarcinoma

Clinical Chemistry and Laboratory Medicine

Volumn 48, Issue 2, 2010, Pages 263-269

  Huang, Qiaojia ^a   Ye, Jianxin ^a   Huang, Qingling ^a   Chen, Wannan ^a   Wang, Lin ^a   Lin, Wansong ^a   Lin, Jianyin ^a   Lin, Xu ^a  

^a FUJIAN MEDICAL UNIVERSITY   (China)

Author keywords

ELISA; Gastric adenocarcinomas; Heat shock protein 27; Immunohistochemistry; Western blot

Indexed keywords

HEAT SHOCK PROTEIN 27; IMMUNOGLOBULIN G;

ADULT; AGED; ARTICLE; CANCER PATIENT; CANCER STAGING; CLINICAL ARTICLE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GENE OVEREXPRESSION; HELICOBACTER PYLORI; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MALE; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; SERUM; STOMACH ADENOCARCINOMA; STOMACH MUCOSA; STOMACH TUMOR; WESTERN BLOTTING;

ADENOCARCINOMA; ADULT; AGED; AGED, 80 AND OVER; BLOTTING, WESTERN; CASE-CONTROL STUDIES; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; HSP27 HEAT-SHOCK PROTEINS; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE AGED; STOMACH NEOPLASMS; TUMOR MARKERS, BIOLOGICAL; UP-REGULATION;

HELICOBACTER PYLORI;

EID: 76649143731     PISSN: 14346621     EISSN: 14374331     Source Type: Journal    
DOI: 10.1515/CCLM.2010.043     Document Type: Article

References (38)

1. Lindquist S, Craig EA. The heat-shock proteins. Annu Rev Genet 1988;22:631-677
2. Gething MJ, Sambrook J. Protein folding in the cell. Nature 1992;355:33-45.
3. Graner MW, Cumming RI, Bigner DD. The heat shock response and chaperones/heat shock proteins in brain tumors: surface expression, release, and possible immune consequences. J Neurosci 2007;27:11214-11227
4. Wu W, Welsh MJ. Expression of the 25-kDa heat-shock protein (HSP27) correlates with resistance to the toxicity of cadmium chloride, mercuric chloride, cis-platinum(II)-diammine dichloride, or sodium arsenite in mouse embryonic stem cells transfected with sense or antisense HSP27 cDNA. Toxicol Appl Pharmacol 1996;141:330-339
5. Ferns G, Shams S, Shafi S. Heat shock protein 27: its potential role in vascular disease. Int J Exp Pathol 2006;87:253-274
6. Garrido C, Brunet M, Didelot C, Zermati Y, Schmitt E, Kroemer G. Heat shock proteins 27 and 70: anti-apoptotic proteins with tumorigenic properties. Cell Cycle 2006;5:2592-2601
7. Vargas-Roig LM, Fanelli MA, Lopez LA, Gago FE, Tello O, Aznar JC, et al. Heat shock proteins and cell proliferation in human breast cancer biopsy samples. Cancer Detect Prev 1997; 21:441-451
8. Ciocca DR, Calderwood SK. Heat shock proteins in cancer: diagnostic, prognostic, predictive, and treatment implications. Cell Stress Chaperones 2005;10:86-103.
9. Melle C, Ernst G, Escher N, Hartmann D, Schimmel B, Bleul A, et al. Protein profiling of microdissected pancreas carcinoma and identification of HSP27 as a potential serum marker. Clin Chem 2007;53:629-637
10. Fanelli MA, Montt-Guevara M, Diblasi AM, Gago FE, Tello O, Cuello-Carrión FD, et al. P-Cadherin and beta-catenin are useful prognostic markers in breast cancer patients; beta-catenin interacts with heat shock protein Hsp27. Cell Stress Chaperones 2008;13:207-220
11. Huang QJ, Huang QL, Chen WN, Wang L, Lin WS, Lin JY, et al. Identification of transgelin as a potential novel biomarker for gastric adenocarcinoma based on proteomics technology. J Cancer Res Clin Oncol 2008;134:1219-1227
12. Long M, Luo J, Li Y, Zeng FY, Li M. Detection and evaluation of antibodies against neutrophil-activating protein of Helicobacter pylori in patients with gastric cancer. World J Gastroenterol 2009;15:2381-2388
13. Kalebi A, Rana F, Mwanda W, Lule G, Hale M. Histopathological profile of gastritis in adult patients seen at a referral hospital in Kenya. World J Gastroenterol 2007;13:4117-4121
14. Edinger AL. Growth factors regulate cell survival by controlling nutrient transporter expression. Biochem Soc Trans 2005; 33:225-227
15. Griguer CE, Oliva CR, Gillespie GY. Glucose metabolism heterogeneity in human and mouse malignant glioma cell lines. J Neurooncol 2005;74:123-133
16. Harguindey S, Orive G, Luis Pedraz J, Paradiso A, Reshkin SJ. The role of pH dynamics and the Na+/H+antiporter in the etiopathogenesis and treatment of cancer. Two faces of the same coin - one single nature. Biochim Biophys Acta 2005;1756: 1-24.
17. Downs CA, Jones LR, Heckathorn SA. Evidence for a novel set of small heat-shock proteins that associates with the mitochondria of murine PC12 cells and protects NADH: ubiquinone oxidoreductase from heat and oxidative stress. Arch Biochem Biophys 1999:365:344-350
18. Dunlop ME, Muggli EE. Small heat shock protein alteration provides a mechanism to reduce mesangial cell contractility in diabetes and oxidative stress. Kidney Int 2000;57:464-475
19. Rust W, Kingsley K, Petnicki T, Padmanabhan S, Carper SW, Plopper GE. Heat shock protein 27 plays two distinct roles in controlling human breast cancer cell migration on laminin-5. Mol Cell Biol Res Commun 1999;1:196-202.
20. Erkizan O, Kirkali G, Yörükoǧlu K, Kirkali Z. Significance of heat shock protein-27 expression in patients with renal cell carcinoma. Urology 2004;64:474-478
21. Choi DH, Ha JS, Lee WH, Song JK, Kim GY, Park JH, et al. Heat shock protein 27 is associated with irinotecan resistance in human colorectal cancer cells. FEBS Lett 2007;581:1649-1656
22. Zanini C, Pulerà F, Carta F, Giribaldi G, Mandili G, Maule MM, et al. Proteomic identification of heat shock protein 27 as a differentiation and prognostic marker in neuroblastoma but not in Ewing's sarcoma. Virchows Arch 2008;452:157-167
23. Oesterreich S, Weng CN, Qiu M, Hilsenbeck SG, Osborne CK, Fuqua SA. The small heat shock protein hsp27 is correlated with growth and drug resistance in human breast cancer cell lines. Cancer Res 1993;53:4443-4448
24. Martín B, Aragüés R, Sanz R, Oliva B, Boluda S, Martínez A, et al. Biological pathways contributing to organ-specific phenotype of brain metastatic cells. J Proteome Res 2008;7: 908-920
25. Ryu JW, Kim HJ, Lee YS, Myong NH, Hwang CH, Lee GS, et al. The proteomics approach to find biomarkers in gastric cancer. J Korean Med Sci 2003;18:505-509
26. Chen J, Kähne T, Röcken C, Götze T, Yu J, Sung JJ, et al. Proteome analysis of gastric cancer metastasis by two-dimensional gel electrophoresis and matrix assisted laser desorption/ ionization-mass spectrometry for identification of metastasisrelated proteins. J Proteome Res 2004;3:1009-1106
27. Takeno S, Noguchi T, Kikuchi R, Sato T, Uchida Y, Yokoyama S. Analysis of the survival period in resectable stage IV gastric cancer. Ann Surg Oncol 2001;8:215-221
28. Kapranos N, Kominea A, Konstantinopoulos PA, Savva S, Artelaris S, Vandoros G, et al. Expression of the 27-kDa heat shock protein (HSP27) in gastric carcinomas and adjacent normal, metaplastic, and dysplastic gastric mucosa, and its prognostic significance. J Cancer Res Clin Oncol 2002;128:426-432
29. Giaginis C, Daskalopoulou SS, Vgenopoulou S, Sfiniadakis I, Kouraklis G, Theocharis SE. Heat shock protein-27, -60 and -90 expression in gastric cancer: association with clinicopathological variables and patient survival. BMC Gastroenterology 2009;9:1-10.
30. Oh TY, Yeo M, Han SU, Cho YK, Kim YB, Chung MH, et al. Synergism of Helicobacter pylori infection and stress on the augmentation of gastric mucosal damage and its prevention with alpha-tocopherol. Free Radic Biol Med 2005;38:1447-1457
31. Nardone G, Rippa E, Martin G, Rocco A, Siciliano RA, Fiengo A, et al. Gastrokine 1 expression in patients with and without Helicobacter pylori infection. Dig Liver Dis 2007;39:122-129
32. Kim CG, Choi IJ, Lee JY, Cho SJ, Nam BH, Kook MC, et al. Biopsy site for detecting Helicobacter pylori infection in patients with gastric cancer. J Gastroenterol Hepatol 2009;24: 469-474
33. Marruchella G, Di Leonardo M, Di Guardo G, Romanucci M, Marà M, Tiscar PG, et al. Heat shock proteins (HSPs) 27, 72 and 73 in normal and pre-ulcerative mucosa of the gastric pars oesophagea in swine. J Comp Pathol 2004;131:10-17
34. Ebert MP, Schäfer C, Chen J, Hoffmann J, Gu P, Kubisch C. Protective role of heat shock protein 27 in gastric mucosal injury. J Pathol 2005;207:177-184
35. Yeo M, Kim DK, Cho SW, Hong HD. Ginseng, the root of Panax ginseng C.A. Meyer, protects ethanol-induced gastric damages in rat through the induction of cytoprotective heatshock protein 27. Dig Dis Sci 2008;53:606-613
36. Cornford PA, Dodson AR, Parsons KF, Desmond AD, Woolfenden A, Fordham M, et al. Heat shock protein expression independently predicts clinical outcome in prostate cancer. Cancer Res 2000;60:7099-7105
37. Storm FK, Mahvi DM, Gilchrist KW. HSP-27 has no diagnostic or prognostic significance in prostate or bladder cancers. Adult Urol 1993:42:379-382
38. Jin HS, Yoshino T, Jin Z, Oka T, Kobayashi K, Yamasaki R, et al. Expression of heat shock protein 60 in normal and neoplastic human lymphoid tissues. J Clin Exp Hematopathol 2002;42:25-32.