Structural insights into triple-helical collagen cleavage by matrix metalloproteinase 1

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 31, 2012, Pages 12461-12466

  Manka, Szymon W ^a   Carafoli, Federico ^b   Visse, Robert ^a   Bihan, Dominique ^c   Raynal, Nicolas ^c   Farndale, Richard W ^c   Murphy, Gillian ^c   Enghild, Jan J ^d   Hohenester, Erhard ^b   Nagase, Hideaki ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b IMPERIAL COLLEGE LONDON   (United Kingdom)

^c UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^d AARHUS UNIVERSITY   (Denmark)

Author keywords

Extracellular matrix; Protease; X ray crystallography

Indexed keywords

COLLAGEN; HEMOPEXIN; INTERSTITIAL COLLAGENASE;

ARTICLE; CARBOXY TERMINAL SEQUENCE; COLLAGEN DEGRADATION; CRYSTAL STRUCTURE; DEUTERIUM HYDROGEN EXCHANGE; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME BINDING; HYDROLYSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN INTERACTION; TEMPERATURE DEPENDENCE;

AMINO ACID SUBSTITUTION; COLLAGEN; HUMANS; MATRIX METALLOPROTEINASE 1; MODELS, MOLECULAR; MUTATION, MISSENSE; PEPTIDE LIBRARY; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, TERTIARY; PROTEOLYSIS;

EID: 84864526140     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1204991109     Document Type: Article

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